| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yasmin Alkhlaif, Deniz Bagdas, Asti Jackson, Abigail J Park, Imad M Dama. Assessment of nicotine withdrawal-induced changes in sucrose preference in mice. Pharmacology, biochemistry, and behavior. vol 161. 2018-06-04. PMID:28919072. |
a sucrose preference time course was performed and the results were compared to another well-established affective sign of nicotine withdrawal, the reduction in time spent in light side, using the light dark box test. |
2018-06-04 |
2023-08-13 |
mouse |
| Yasmin Alkhlaif, Deniz Bagdas, Asti Jackson, Abigail J Park, Imad M Dama. Assessment of nicotine withdrawal-induced changes in sucrose preference in mice. Pharmacology, biochemistry, and behavior. vol 161. 2018-06-04. PMID:28919072. |
subsequently, our results demonstrated a time-dependent and dose-related reduction in sucrose preference in nicotine withdrawn male c57bl/6j mice, indicative of a decrease in responding for positive affective stimuli. |
2018-06-04 |
2023-08-13 |
mouse |
| Yasmin Alkhlaif, Deniz Bagdas, Asti Jackson, Abigail J Park, Imad M Dama. Assessment of nicotine withdrawal-induced changes in sucrose preference in mice. Pharmacology, biochemistry, and behavior. vol 161. 2018-06-04. PMID:28919072. |
we also found the reduction for positive affective stimuli and time spent in the light side was not present in nicotine withdrawn β2 and α6 ko mice, suggesting that these nicotinic subunits are involved in the affective signs of nicotine withdrawal. |
2018-06-04 |
2023-08-13 |
mouse |
| Yasmin Alkhlaif, Deniz Bagdas, Asti Jackson, Abigail J Park, Imad M Dama. Assessment of nicotine withdrawal-induced changes in sucrose preference in mice. Pharmacology, biochemistry, and behavior. vol 161. 2018-06-04. PMID:28919072. |
thus, this report highlights the potential utility of the sucrose preference test as a useful measure of the decrease in responding for positive affective stimuli during spontaneous nicotine withdrawal. |
2018-06-04 |
2023-08-13 |
mouse |
| Steven J Simmons, Taylor A Gentile, Lili Mo, Fionya H Tran, Sisi Ma, John W Muscham. Nicotinic receptor blockade decreases fos immunoreactivity within orexin/hypocretin-expressing neurons of nicotine-exposed rats. Behavioural brain research. vol 314. 2018-01-18. PMID:27491589. |
nicotine withdrawal is characterized by negative affective and cognitive symptoms that enhance relapse susceptibility, and suppressed dopaminergic transmission from ventral tegmental area (vta) to target structures underlies behavioral symptoms of nicotine withdrawal. |
2018-01-18 |
2023-08-13 |
rat |
| Jason D Robinson, Francesco Versace, Jeffery M Engelmann, Yong Cui, David G Gilbert, Andrew J Waters, Ellen R Gritz, Paul M Cinciripin. Attentional bias to smoking and other motivationally relevant cues is affected by nicotine exposure and dose expectancy. Journal of psychopharmacology (Oxford, England). vol 30. issue 7. 2017-12-27. PMID:27097731. |
we investigated the effects of acute nicotine dose and expected dose on attentional bias (ab) to smoking and affective cues in overnight nicotine-deprived smokers (n=51; 24 women) using a balanced placebo design, which counterbalanced given nicotine dose (given-nic vs. given-denic) with instructed nicotine dose expectancy (told-nic vs. told-denic). |
2017-12-27 |
2023-08-13 |
Not clear |
| Joseph A Pipkin, Bryan Cruz, Rodolfo J Flores, Cecilia A Hinojosa, Luis M Carcoba, Melissa Ibarra, Wendy Francis, Arbi Nazarian, Laura E O'Del. Both nicotine reward and withdrawal are enhanced in a rodent model of diabetes. Psychopharmacology. vol 234. issue 9-10. 2017-12-13. PMID:28342091. |
it is presently unclear whether diabetic rats experience greater rewarding effects of nicotine and/or negative affective states produced by nicotine withdrawal. |
2017-12-13 |
2023-08-13 |
rat |
| Jeremy C Borniger, Reuben F Don, Ning Zhang, R Thomas Boyd, Randy J Nelso. Enduring effects of perinatal nicotine exposure on murine sleep in adulthood. American journal of physiology. Regulatory, integrative and comparative physiology. vol 313. issue 3. 2017-09-25. PMID:28637659. |
to this end, we investigated potential enduring effects of perinatal nicotine exposure on murine sleep and affective behaviors in adulthood (~13-15 wk of age) in c57bl6j mice. |
2017-09-25 |
2023-08-13 |
mouse |
| b' A Simonnet, E Zamberletti, M Cador, T Rubino, S Caill\\xc3\\xa. Chronic FAAH inhibition during nicotine abstinence alters habenular CB1 receptor activity and precipitates depressive-like behaviors. Neuropharmacology. vol 113. issue Pt A. 2017-07-11. PMID:27737788.' |
acute inhibition of anandamide (aea) degradation efficiently reduces nicotine withdrawal-induced affective symptoms in rats and fatty acid amide hydrolase (faah), the degradation enzyme of aea, has been proposed as a possible treatment against nicotine addiction. |
2017-07-11 |
2023-08-13 |
rat |
| b' A Simonnet, E Zamberletti, M Cador, T Rubino, S Caill\\xc3\\xa. Chronic FAAH inhibition during nicotine abstinence alters habenular CB1 receptor activity and precipitates depressive-like behaviors. Neuropharmacology. vol 113. issue Pt A. 2017-07-11. PMID:27737788.' |
however, it is unclear whether chronic inhibition of aea during nicotine abstinence will have beneficial or deleterious affective side-effects. |
2017-07-11 |
2023-08-13 |
rat |
| Xueyan Pang, Liwang Liu, Jennifer Ngolab, Rubing Zhao-Shea, J Michael McIntosh, Paul D Gardner, Andrew R Tappe. Habenula cholinergic neurons regulate anxiety during nicotine withdrawal via nicotinic acetylcholine receptors. Neuropharmacology. vol 107. 2017-06-19. PMID:27020042. |
cholinergic neurons in the medial habenula (mhb) modulate anxiety during nicotine withdrawal although the molecular neuroadaptation(s) within the mhb that induce affective behaviors during nicotine cessation is largely unknown. |
2017-06-19 |
2023-08-13 |
mouse |
| F Scott Hall, Andre Der-Avakian, Thomas J Gould, Athina Markou, Mohammed Shoaib, Jared W Youn. Negative affective states and cognitive impairments in nicotine dependence. Neuroscience and biobehavioral reviews. vol 58. 2016-09-19. PMID:26054790. |
negative affective states and cognitive impairments in nicotine dependence. |
2016-09-19 |
2023-08-13 |
human |
| F Scott Hall, Andre Der-Avakian, Thomas J Gould, Athina Markou, Mohammed Shoaib, Jared W Youn. Negative affective states and cognitive impairments in nicotine dependence. Neuroscience and biobehavioral reviews. vol 58. 2016-09-19. PMID:26054790. |
although most animal models of nicotine dependence emphasize the positive reinforcing effects of nicotine as the major motivational force behind nicotine use, smokers generally report that other consequences of nicotine use, including the ability of nicotine to alleviate negative affective states or cognitive impairments, as reasons for continued smoking. |
2016-09-19 |
2023-08-13 |
human |
| F Scott Hall, Andre Der-Avakian, Thomas J Gould, Athina Markou, Mohammed Shoaib, Jared W Youn. Negative affective states and cognitive impairments in nicotine dependence. Neuroscience and biobehavioral reviews. vol 58. 2016-09-19. PMID:26054790. |
these states could result from nicotine withdrawal, but also may be associated with premorbid differences in affective and/or cognitive function. |
2016-09-19 |
2023-08-13 |
human |
| Peter Muelken, Clare E Schmidt, David Shelley, Laura Tally, Andrew C Harri. A Two-Day Continuous Nicotine Infusion Is Sufficient to Demonstrate Nicotine Withdrawal in Rats as Measured Using Intracranial Self-Stimulation. PloS one. vol 10. issue 12. 2016-06-26. PMID:26658557. |
avoidance of the negative affective (emotional) symptoms of nicotine withdrawal (e.g., anhedonia, anxiety) contributes to tobacco addiction. |
2016-06-26 |
2023-08-13 |
rat |
| Peter Muelken, Clare E Schmidt, David Shelley, Laura Tally, Andrew C Harri. A Two-Day Continuous Nicotine Infusion Is Sufficient to Demonstrate Nicotine Withdrawal in Rats as Measured Using Intracranial Self-Stimulation. PloS one. vol 10. issue 12. 2016-06-26. PMID:26658557. |
establishing the minimal nicotine exposure conditions required to demonstrate negative affective withdrawal signs in animals, as well as understanding moderators of these conditions, could inform tobacco addiction-related research, treatment, and policy. |
2016-06-26 |
2023-08-13 |
rat |
| Rebecca L Pomfrey, Tamaara A Bostwick, B Bradley Wetzell, Anthony L Rile. Adolescent nicotine exposure fails to impact cocaine reward, aversion and self-administration in adult male rats. Pharmacology, biochemistry, and behavior. vol 137. 2016-06-24. PMID:26255152. |
these studies demonstrate that adolescent nicotine pre-exposure does not have an impact on cocaine's affective properties or its self-administration at least with the specific parametric conditions under which these effects were tested. |
2016-06-24 |
2023-08-13 |
human |
| Bridgin G Lee, Agustin Anastasia, Barbara L Hempstead, Francis S Lee, Julie A Blend. Effects of the BDNF Val66Met Polymorphism on Anxiety-Like Behavior Following Nicotine Withdrawal in Mice. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 17. issue 12. 2016-06-22. PMID:25744957. |
nicotine withdrawal is characterized by both affective and cognitive symptoms. |
2016-06-22 |
2023-08-13 |
mouse |
| Kia J Jackson, Asti Jackson, F Ivy Carroll, M Imad Dama. Effects of orally-bioavailable short-acting kappa opioid receptor-selective antagonist LY2456302 on nicotine withdrawal in mice. Neuropharmacology. vol 97. 2016-05-24. PMID:26044637. |
mice were chronically treated with nicotine for 14 days and physical and affective nicotine withdrawal signs were measured using a spontaneous nicotine withdrawal model and conditioned place aversion (cpa) following pre-treatment with ly2456302, administered orally. |
2016-05-24 |
2023-08-13 |
mouse |
| Jason D Robinson, Jeffery M Engelmann, Yong Cui, Francesco Versace, Andrew J Waters, David G Gilbert, Ellen R Gritz, Paul M Cinciripin. The effects of nicotine dose expectancy and motivationally relevant distracters on vigilance. Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors. vol 28. issue 3. 2016-05-05. PMID:24841184. |
this study investigated the effects of nicotine availability on attentional bias to smoking, affective, and neutral cues in a sample of adult smokers during a vigilance task. |
2016-05-05 |
2023-08-13 |
human |