| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dandan Jia, Beisha Tang, Yuting Shi, Junling Wang, Zhanfang Sun, Zhao Chen, Li Zhang, Kun Xia, Hong Jian. A deletion mutation of the VHL gene associated with a patient with sporadic von Hippel-Lindau disease. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 20. issue 6. 2014-01-09. PMID:23632291. |
a deletion mutation of the vhl gene associated with a patient with sporadic von hippel-lindau disease. |
2014-01-09 |
2023-08-12 |
human |
| Katarzyna Labno-Kirszniok, Teresa Nieszporek, Andrzej Wiecek, Grzegorz Helbig, Jan Lubinsk. Acute myeloid leukemia in a 38-year-old hemodialyzed patient with von Hippel-Lindau disease. Hereditary cancer in clinical practice. vol 11. issue 1. 2013-11-15. PMID:23968328. |
von hippel-lindau disease (vhl disease) is a hereditary cancer predisposition syndrome caused by mutations of the von hippel-lindau tumor suppressor gene. |
2013-11-15 |
2023-08-12 |
Not clear |
| Alexander O Vortmeyer, Eric A Falke, Sven Gläsker, Jie Li, Edward H Oldfiel. Nervous system involvement in von Hippel-Lindau disease: pathology and mechanisms. Acta neuropathologica. vol 125. issue 3. 2013-09-04. PMID:23400300. |
patients with von hippel-lindau disease carry a germline mutation of the von hippel-lindau (vhl) tumor-suppressor gene. |
2013-09-04 |
2023-08-12 |
Not clear |
| Chunzhang Yang, Kristin Huntoon, Alexander Ksendzovsky, Zhengping Zhuang, Russell R Lonse. Proteostasis modulators prolong missense VHL protein activity and halt tumor progression. Cell reports. vol 3. issue 1. 2013-07-16. PMID:23318261. |
although missense mutations of the von hippel-lindau disease (vhl) gene are the most common germline mutation underlying this heritable cancer syndrome, the mechanism of tumorigenesis is unknown. |
2013-07-16 |
2023-08-12 |
Not clear |
| E M Berge, D W Bowles, T W Flaig, E T Lam, A Jimen. Tivozanib: practical implications for renal cell carcinoma and other solid tumors. Drugs of today (Barcelona, Spain : 1998). vol 49. issue 5. 2013-07-10. PMID:23724410. |
given known relevance of vhl (von hippel-lindau disease tumor suppressor) deregulation in the clear cell variant of renal cell carcinoma, renal cell carcinoma remains an area of interest and subject of recent registration trials with this approach. |
2013-07-10 |
2023-08-12 |
human |
| Hiroshi Kanno, Jun-ichi Kuratsu, Ryo Nishikawa, Kazuhiko Mishima, Atushi Natsume, Toshihiko Wakabayashi, Kiyohiro Houkin, Shunsuke Terasaka, Taro Shui. Clinical features of patients bearing central nervous system hemangioblastoma in von Hippel-Lindau disease. Acta neurochirurgica. vol 155. issue 1. 2013-06-25. PMID:23080552. |
central nervous system (cns) hemangioblastoma (hb) is one of the most common manifestations in von hippel-lindau disease (vhl), but large-scale studies on clinical features of cns hb in vhl are scarce. |
2013-06-25 |
2023-08-12 |
Not clear |
| S R Galan, P H Kan. Genetics and molecular pathogenesis of pheochromocytoma and paraganglioma. Clinical endocrinology. vol 78. issue 2. 2013-06-06. PMID:23061808. |
at present, these are ret proto-oncogene, von hippel-lindau disease tumor suppressor gene (vhl), neurofibromatosis type 1 tumor suppressor gene (nf1), genes encoding the succinate dehydrogenase (sdh) complex subunits sdhb, sdhc, and sdhd, but also sdha, the gene encoding the enzyme responsible for the flavination of sdha (sdhaf2 or hsdh5), and the newly described tmem127 and max tumor suppressor genes. |
2013-06-06 |
2023-08-12 |
Not clear |
| Michael Adly Mikhail, Jia Ng, Joseph Mathew, Zachariah Kosh. Von Hippel Lindau disease: keep it in the family. BMJ case reports. vol 2012. 2013-06-04. PMID:23242101. |
we describe a case of von hippel-lindau disease (vhl) through three generations of the same family. |
2013-06-04 |
2023-08-12 |
Not clear |
| Sandeep G Jakhere, Bhakti Yeragi, Darshan G Jai. Von Hippel Lindau disease [VHL]: magnetic resonance imaging spectrum in a single patient. Acta medica Indonesiana. vol 44. issue 4. 2013-05-24. PMID:23314974. |
von hippel lindau disease [vhl]: magnetic resonance imaging spectrum in a single patient. |
2013-05-24 |
2023-08-12 |
Not clear |
| A B González Escobar, M J Morillo Sánchez, J M García-Campo. [Von Hippel-Lindau disease: family study]. Archivos de la Sociedad Espanola de Oftalmologia. vol 87. issue 11. 2013-03-28. PMID:23058196. |
the case of 5 members of a family who suffer from von hippel-lindau disease (vhl) is presented. |
2013-03-28 |
2023-08-12 |
Not clear |
| Robert Pilarski, Rebecca Nag. Genetic testing by cancer site: endocrine system. Cancer journal (Sudbury, Mass.). vol 18. issue 4. 2013-01-30. PMID:22846739. |
the primary syndromes (and genes) addressed here include multiple endocrine neoplasia types 1 and 2 (men1 and ret genes), cowden syndrome (pten), hereditary pheochromocytoma/paraganglioma syndromes (multiple genes), and von hippel-lindau disease (vhl). |
2013-01-30 |
2023-08-12 |
Not clear |
| Simon Turcotte, Baris Turkbey, Stephanie Barak, Steven K Libutti, H Richard Alexander, W Marston Linehan, Marybeth S Hughes, Naris Nilubol, Krisana Gesuwan, Corina Millo, Martha Quezado, Peter L Choyke, Electron Kebebew, Giao Q Pha. von Hippel-Lindau disease-associated solid microcystic serous adenomas masquerading as pancreatic neuroendocrine neoplasms. Surgery. vol 152. issue 6. 2013-01-22. PMID:23107912. |
patients with von hippel-lindau disease (vhl) commonly develop pancreatic cysts and neuroendocrine neoplasms (pnens or pnets). |
2013-01-22 |
2023-08-12 |
Not clear |
| Jin Zhang, Jia-Hua Pan, Bai-Jun Dong, Wei Xue, Dong-Ming Liu, Yi-Ran Huan. Active surveillance of renal masses in von Hippel-Lindau disease: growth rates and clinical outcome over a median follow-up period of 56 months. Familial cancer. vol 11. issue 2. 2012-11-30. PMID:22203439. |
to evaluate the natural outcome of a surveillance strategy for enhancing renal masses associated with von hippel-lindau disease (vhl). |
2012-11-30 |
2023-08-12 |
Not clear |
| Yuhao Sun, Qingfang Sun, Jiankang Shen, Huacheng Wu, Yongjing Guan, Kan Gong, Liuguan Bia. Cauda equina hemangioblastoma at L5 vertebral level related to von Hippel-Lindau disease. British journal of neurosurgery. vol 26. issue 4. 2012-11-26. PMID:22133049. |
hemangioblastoma (hb) is uncommon, with only a few cases of hemangioblastoma with von hippel-lindau disease (vhl) located in cauda equina previously reported. |
2012-11-26 |
2023-08-12 |
Not clear |
| Taro Shuin, Masahiro Yao, Nobuo Shinohara, Ichiro Yamasaki, Kenji Tamur. [Clinical status of Von Hippel-Lindau disease associated pheochromocytoma in Japan: a national epidemiologic survey]. Nihon Hinyokika Gakkai zasshi. The japanese journal of urology. vol 103. issue 3. 2012-11-13. PMID:22876661. |
to understand the current clinical status of pheochromocytoma (pheo) in patients with von hippel-lindau disease (vhl) in japan. |
2012-11-13 |
2023-08-12 |
Not clear |
| Stanley Park, Chi-Chao Cha. Von Hippel-Lindau disease (VHL): a need for a murine model with retinal hemangioblastoma. Histology and histopathology. vol 27. issue 8. 2012-11-06. PMID:22763871. |
von hippel-lindau disease (vhl): a need for a murine model with retinal hemangioblastoma. |
2012-11-06 |
2023-08-12 |
human |
| B Bausch, A Malinoc, L Maruschke, C Offergeld, S Gläsker, H C Rischke, M Brauckhoff, C C Boedeker, H P H Neuman. [Genetics of pheochromocytoma]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen. vol 83. issue 6. 2012-11-05. PMID:22481546. |
this group is composed of the entities of multiple endocrine neoplasia type 2 (men2) due to mutations in the ret gene, von hippel-lindau disease (vhl, vhl gene), the paraganglioma syndromes types 1-4 (pgl1-4) due to mutations of the genes sdhd, sdhaf2, sdhc, sdhb, neurofibromatosis type 1 (nf1) due to mutations of the nf1 gene and familial pheochromocytoma syndromes due to mutations of the sdha, tmem127 and max genes. |
2012-11-05 |
2023-08-12 |
Not clear |
| L Wiklund, M Nordling, J Wahlstrom, Y Engwall, T Martinsso. Novel germline mutations in Swedish von Hippel-Lindau disease patients. International journal of oncology. vol 11. issue 3. 2012-10-02. PMID:21528239. |
we have used a combination of different mutation detection systems in analyzing two swedish families with von hippel-lindau disease (vhl). |
2012-10-02 |
2023-08-12 |
Not clear |
| K Uzawa, H Suzuki, H Yokoe, H Tanzawa, K Sat. Mutational state of p16/cdkn2 and vhl genes in squamous-cell carcinoma of the oral cavity. International journal of oncology. vol 7. issue 4. 2012-10-02. PMID:21552920. |
two new tumor-suppressor genes, the cyclin dependent kinase 4 inhibitor gene (p16/cdkn2) and the von hippel-lindau disease gene (vhl), have been cloned and mapped on chromosomes 9p and 3p respectively, where putative tumor-suppressor genes of the oral squamous-cell carcinoma (scc) may be present. |
2012-10-02 |
2023-08-12 |
human |
| R Nakashima, T Enomoto, M Fujita, K Yoshino, H Wada, K Kondo, M Yao, Y Murat. The von-Hippel-Lindau (VHL) tumor suppressor gene is not mutated in sporadic ovarian carcinomas. Oncology reports. vol 3. issue 5. 2012-10-02. PMID:21594475. |
the von hippel-lindau (vhl) tumor suppressor gene has been shown to be mutated frequently not only in neoplasms from von hippel-lindau disease, but also in sporadic clear cell renal carcinoma. |
2012-10-02 |
2023-08-12 |
Not clear |