All Relations between von Hippel-Lindau Disease and vhl

Publication Sentence Publish Date Extraction Date Species
Simon Kirste, Alexander Rühle, Stefan Zschiedrich, Wolfgang Schultze-Seemann, Cordula A Jilg, Elke Neumann-Haefelin, Simon S Lo, Anca-Ligia Grosu, Emily Ki. Stereotactic Body Radiotherapy for Renal Cell Carcinoma in Patients with Von Hippel-Lindau Disease-Results of a Prospective Trial. Cancers. vol 14. issue 20. 2022-10-27. PMID:36291853. von hippel-lindau disease (vhl) is a hereditary disorder associated with malignant tumors including clear cell renal cell carcinoma (ccrcc). 2022-10-27 2023-08-14 Not clear
Rodrigo A Toledo, Camilo Jimenez, Gustavo Armaiz-Pena, Carlota Arenillas, Jaume Capdevila, Patricia L M Dahi. Hypoxia Inducible factor 2 alpha (HIF2α) inhibitors: targeting genetically driven tumor hypoxia. Endocrine reviews. 2022-10-27. PMID:36301191. belzutifan, a highly specific and well-tolerated hif2α inhibitor, recently received fda approval for the treatment of nonmetastatic renal cell carcinomas, pancreatic neuroendocrine tumors, and central nervous system hemangioblastomas from patients with von hippel lindau disease, who carry vhl germline mutations. 2022-10-27 2023-08-14 Not clear
William G Kaeli. Von Hippel-Lindau disease: insights into oxygen sensing, protein degradation, and cancer. The Journal of clinical investigation. vol 132. issue 18. 2022-09-15. PMID:36106637. germline loss-of-function mutations of the vhl tumor suppressor gene cause von hippel-lindau disease, which is associated with an increased risk of hemangioblastomas, clear cell renal cell carcinomas (ccrccs), and paragangliomas. 2022-09-15 2023-08-14 Not clear
Elysa Bond, Beverly Yashar, Tobias Else, Jenae Osborne, Monica Marvi. Disclosure of genetic risk to dating partners among young adults with von Hippel-Lindau disease. Familial cancer. 2022-08-19. PMID:35984582. while previous studies have explored the impact of hereditary breast and ovarian cancer syndrome on dating, research investigating psychosocial implications for young adults with early-onset multi-organ tumor predisposition syndromes such as von hippel-lindau disease (vhl) is scarce. 2022-08-19 2023-08-14 human
Hiroki Natsui, Junji Kohisa, Seiichi Yoshikawa, Manabu Takeuchi, Ryoma Yagi, Masahiro Minagawa, Tatsuo Tani, Hiroyuki Usuda, Shuji Tera. Tumor-to-tumor metastasis of colon cancer metastasizing to a pancreatic neuroendocrine tumor associated with von Hippel-Lindau disease: a case report. Clinical journal of gastroenterology. 2022-08-11. PMID:35951216. von hippel-lindau disease (vhl) is frequently associated with pancreatic neuroendocrine tumors (pnets). 2022-08-11 2023-08-14 Not clear
Marie Louise M Binderup, Maja Smerdel, Line Borgwadt, Signe Sparre Beck Nielsen, Mia Gebauer Madsen, Hans Ulrik Møller, Jens Folke Kiilgaard, Lennart Friis-Hansen, Vibeke Harbud, Søren Cortnum, Hanne Owen, Steen Gimsing, Henning Anker Friis Juhl, Sune Munthe, Marianne Geilswijk, Åse Krogh Rasmussen, Ulla Møldrup, Ole Graumann, Frede Donskov, Henning Grønbæk, Brian Stausbøl-Grøn, Ove Schaffalitzky de Muckadell, Ulrich Knigge, Gitte Dam, Karin Aw Wadt, Lars Bøgeskov, Per Bagi, Lars Lund, Kirstine Stochholm, Lilian Bomme Ousager, Lone Sund. von Hippel-Lindau disease: Updated guideline for diagnosis and surveillance. European journal of medical genetics. 2022-06-16. PMID:35709961. von hippel lindau disease (vhl) is caused by a hereditary predisposition to multiple neoplasms, especially hemangioblastomas in the retina and cns, renal cell carcinomas (rcc), pheochromocytomas, neuroendocrine pancreatic tumours (pnet) and endolymphatic sac tumours. 2022-06-16 2023-08-14 Not clear
Mariana Fuertes, Belén Elguero, David Gonilski-Pacin, Florencia Herbstein, Josefina Rosmino, Nicolas Ciancio Del Giudice, Manuel Fiz, Lara Falcucci, Eduardo Arz. Impact of RSUME Actions on Biomolecular Modifications in Physio-Pathological Processes. Frontiers in endocrinology. vol 13. 2022-05-09. PMID:35528020. furthermore, rsume suppresses ubiquitin conjugation to hypoxia-inducible factor (hif) by blocking vhl e3-ubiquitin ligase activity, contributing to the development of von hippel-lindau disease. 2022-05-09 2023-08-13 Not clear
Avgi Andreou, Bryndis Yngvadottir, Laia Bassaganyas, Graeme Clarke, Ezequiel Martin, James Whitworth, Alex J Cornish, Richard S Houlston, Philip Rich, Catherine Egan, Shirley V Hodgson, Anne Y Warren, Katie Snape, Eamonn R Mahe. Elongin C (ELOC/TCEB1) associated von Hippel-Lindau disease. Human molecular genetics. 2022-03-24. PMID:35323939. around 95% of patients with clinical features diagnostic of von hippel-lindau disease (vhl) have a detectable inactivating germline variant in vhl. 2022-03-24 2023-08-13 Not clear
Leslie E Oldfield, Jessica Grzybowski, Sylvie Grenier, Elizabeth Chao, Gregory S Downs, Kirsten M Farncombe, Tracy L Stockley, Ozgur Mete, Raymond H Ki. VHL mosaicism: the added value of multi-tissue analysis. NPJ genomic medicine. vol 7. issue 1. 2022-03-19. PMID:35304467. von hippel-lindau disease (vhl) is an autosomal dominant, inherited syndrome with variants in the vhl gene causing predisposition to multi-organ benign and malignant neoplasms. 2022-03-19 2023-08-13 Not clear
Petra Hudler, Mojca Urbanci. The Role of VHL in the Development of von Hippel-Lindau Disease and Erythrocytosis. Genes. vol 13. issue 2. 2022-02-25. PMID:35205407. the role of vhl in the development of von hippel-lindau disease and erythrocytosis. 2022-02-25 2023-08-13 Not clear
Petra Hudler, Mojca Urbanci. The Role of VHL in the Development of von Hippel-Lindau Disease and Erythrocytosis. Genes. vol 13. issue 2. 2022-02-25. PMID:35205407. von hippel-lindau disease (vhl disease or vhl syndrome) is a familial multisystem neoplastic syndrome stemming from germline disease-associated variants of the 2022-02-25 2023-08-13 Not clear
O Nabih, H Hamdani, L El Maaloum, B Allali, A El Kettan. Retinal angioma of Von hippel-lindau disease: A case report. Annals of medicine and surgery (2012). vol 74. 2022-02-11. PMID:35145668. von hippel-lindau disease (vhl), also known as von hippel-lindau syndrome, is a rare genetic disorder with multisystem involvement. 2022-02-11 2023-08-13 Not clear
João Castro-Teles, Bernardo Sousa-Pinto, Sandra Rebelo, Duarte Pignatell. Pheochromocytomas and paragangliomas in von Hippel-Lindau disease: not a needle in a haystack. Endocrine connections. vol 10. issue 11. 2021-12-03. PMID:34596579. pheochromocytomas are a hallmark feature of von hippel-lindau disease (vhl). 2021-12-03 2023-08-13 Not clear
Sarah D Mahan, Kristin M Riching, Marjeta Urh, Danette L Daniel. Kinetic Detection of E3:PROTAC:Target Ternary Complexes Using NanoBRET Technology in Live Cells. Methods in molecular biology (Clifton, N.J.). vol 2365. 2021-11-18. PMID:34432243. here, we present cellular assays utilizing nanobret technology for the study of ternary complexes, showing examples with two most popular protac e3 ligase components, vhl (von hippel-lindau disease tumor suppressor) and crbn (cereblon). 2021-11-18 2023-08-13 Not clear
Isabel de Rojas-P, Virginia Albiñana, Lyudmyla Taranets, Lucía Recio-Poveda, Angel M Cuesta, Nikita Popov, Thales Kronenberger, Luisa M Botell. The Endothelial Landscape and Its Role in Von Hippel-Lindau Disease. Cells. vol 10. issue 9. 2021-11-16. PMID:34571962. von hippel-lindau disease (vhl) is a rare hereditary disease characterized by the predisposal to develop different types of highly vascularized tumors. 2021-11-16 2023-08-13 Not clear
Shachar Laks, Rachel van Leeuwaarde, Dhaval Patel, Xavier M Keutgen, Pascal Hammel, Naris Nilubol, Thera P Links, Thorvardur R Halfdanarson, Anthony B Daniels, Amit Tiros. Management recommendations for pancreatic manifestations of von Hippel-Lindau disease. Cancer. 2021-11-04. PMID:34735022. von hippel-lindau disease (vhl) is a multineoplasm inherited disease manifesting with hemangioblastoma of the central nervous system and retina, adrenal pheochromocytoma, renal cell carcinoma, pancreatic neuroendocrine tumors and cysts, and neoplasms/cysts of the ear, broad ligament, and testicles. 2021-11-04 2023-08-13 Not clear
Mitsuaki Ishida, Hisanori Shiomi, Shigeyuki Naka, Tohru Tani, Hidetoshi Okab. Clear cell neuroendocrine tumor G1 of the gallbladder without von Hippel-Lindau disease. Oncology letters. vol 4. issue 6. 2021-10-21. PMID:23205114. clear cell neuroendocrine tumor (net) is a rare but distinct histopathological variant of net most often observed in patients with von hippel-lindau disease (vhl). 2021-10-21 2023-08-12 Not clear
Eric K Chin, Rupan Trikha, Lawrence S Morse, Robert J Zawadzki, John S Werner, Susanna S Par. Optical Coherence Tomography Findings of Exophytic Retinal Capillary Hemangiomas of the Posterior Pole. Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye. 2021-10-20. PMID:20337341. exophytic retinal capillary hemangiomas (rch) can be a diagnostic challenge in subjects without von hippel-lindau disease (vhl). 2021-10-20 2023-08-12 human
I Y Pita-Ortiz, J N Jaurrieta-Hinojo, I Espinosa-Soto, A Ramirez-Estudill. Primary and secondary retinal capillary haemangioma in Mexico. Archivos de la Sociedad Espanola de Oftalmologia. vol 96. issue 6. 2021-10-15. PMID:34092289. there were seven primary haemangioblastomas, and nine due to von hippel-lindau disease (vhl). 2021-10-15 2023-08-13 Not clear
Kristin Huntoon, Matthew J Shepard, Rimas V Lukas, Ian E McCutcheon, Anthony B Daniels, Ashok R Asthagir. Hemangioblastoma diagnosis and surveillance in von Hippel-Lindau disease: a consensus statement. Journal of neurosurgery. 2021-10-01. PMID:34598132. hemangioblastomas are a frequent underlying cause of neurological morbidity and death in patients with von hippel-lindau disease (vhl). 2021-10-01 2023-08-13 Not clear