All Relations between Tuberous Sclerosis and tsc2

Publication Sentence Publish Date Extraction Date Species
J I Everitt, D C Wolf, S R Howe, T L Goldsworthy, C Walke. Rodent model of reproductive tract leiomyomata. Clinical and pathological features. The American journal of pathology. vol 146. issue 6. 1995-07-13. PMID:7778693. the tumors develop as a result of a germline mutation in the tuberous sclerosis 2 (tsc2) gene, and predisposition to tumor development is inherited in an autosomal dominant fashion. 1995-07-13 2023-08-12 human
T Kobayashi, Y Hirayama, E Kobayashi, Y Kubo, O Hin. A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer. Nature genetics. vol 9. issue 1. 1995-05-11. PMID:7704028. a germline insertion in the tuberous sclerosis (tsc2) gene gives rise to the eker rat model of dominantly inherited cancer. 1995-05-11 2023-08-12 human
T Kobayashi, Y Hirayama, E Kobayashi, Y Kubo, O Hin. A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer. Nature genetics. vol 9. issue 1. 1995-05-11. PMID:7704028. we have previously established a new conserved linkage group on rat chromosome 10q and human chromosome 16p13.3, and shown that the eker mutation is tightly linked to the tuberous sclerosis (tsc2) gene. 1995-05-11 2023-08-12 human
P T Brook-Carter, B Peral, C J Ward, P Thompson, J Hughes, M M Maheshwar, M Nellist, V Gamble, P C Harris, J R Sampso. Deletion of the TSC2 and PKD1 genes associated with severe infantile polycystic kidney disease--a contiguous gene syndrome. Nature genetics. vol 8. issue 4. 1995-04-26. PMID:7894481. major genes which cause tuberous sclerosis (tsc) and autosomal dominant polycystic kidney disease (adpkd), known as tsc2 and pkd1 respectively, lie immediately adjacent to each other on chromosome 16p. 1995-04-26 2023-08-12 Not clear
Y Kubo, F Klimek, Y Kikuchi, P Bannasch, O Hin. Early detection of Knudson's two-hits in preneoplastic renal cells of the Eker rat model by the laser microdissection procedure. Cancer research. vol 55. issue 5. 1995-03-30. PMID:7867009. we previously reported that ionizing radiation induces additional tumors (large adenomas and carcinomas) in a linear dose-response relationship and that loss of heterozygosity (loh) at chromosome 10, where the predisposing tuberous sclerosis (tsc2) gene is localized, was found in the renal cell carcinomas which developed from hybrid f1 rats carrying the eker mutation, indicating that in heterozygotes two events (one inherited, one somatic) are necessary to produce at least large adenomas and carcinomas. 1995-03-30 2023-08-12 rat
A J Green, P H Johnson, J R Yate. The tuberous sclerosis gene on chromosome 9q34 acts as a growth suppressor. Human molecular genetics. vol 3. issue 10. 1995-03-16. PMID:7849709. we have previously demonstrated allele loss in hamartomas from patients with tuberous sclerosis for markers spanning the tuberous sclerosis gene on chromosome 16q13.3 (tsc2). 1995-03-16 2023-08-12 Not clear
A J Green, P H Johnson, J R Yate. The tuberous sclerosis gene on chromosome 9q34 acts as a growth suppressor. Human molecular genetics. vol 3. issue 10. 1995-03-16. PMID:7849709. germline deletions in the tsc2 gene have been shown in 5% of patients with tuberous sclerosis (tsc). 1995-03-16 2023-08-12 Not clear
R S Yeung, G H Xiao, F Jin, W C Lee, J R Testa, A G Knudso. Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 24. 1994-12-27. PMID:7972075. predisposition to renal carcinoma in the eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (tsc2) gene. 1994-12-27 2023-08-12 human
R S Yeung, G H Xiao, F Jin, W C Lee, J R Testa, A G Knudso. Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 24. 1994-12-27. PMID:7972075. this region is syntenic with human chromosome band 16p13.3, the site of the tuberous sclerosis 2 (tsc2) gene. 1994-12-27 2023-08-12 human
O Hino, T Kobayashi, H Tsuchiya, Y Kikuchi, E Kobayashi, H Mitani, Y Hirayam. The predisposing gene of the Eker rat inherited cancer syndrome is tightly linked to the tuberous sclerosis (TSC2) gene. Biochemical and biophysical research communications. vol 203. issue 2. 1994-10-18. PMID:7916573. the predisposing gene of the eker rat inherited cancer syndrome is tightly linked to the tuberous sclerosis (tsc2) gene. 1994-10-18 2023-08-12 human
O Hino, T Kobayashi, H Tsuchiya, Y Kikuchi, E Kobayashi, H Mitani, Y Hirayam. The predisposing gene of the Eker rat inherited cancer syndrome is tightly linked to the tuberous sclerosis (TSC2) gene. Biochemical and biophysical research communications. vol 203. issue 2. 1994-10-18. PMID:7916573. in this study, using 129 backcross animals, we have established a new conserved linkage group on rat 10q and human 16p13.3 whereby the eker mutation was found to be tightly linked to the tuberous sclerosis (tsc2) gene. 1994-10-18 2023-08-12 human