All Relations between Tuberous Sclerosis and mtor

Publication Sentence Publish Date Extraction Date Species
Ariel F Castro, John F Rebhun, Geoffrey J Clark, Lawrence A Quillia. Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner. The Journal of biological chemistry. vol 278. issue 35. 2003-10-02. PMID:12842888. recently the tuberous sclerosis complex 2 (tsc2) tumor suppressor gene product has been identified as a negative regulator of protein synthesis upstream of the mtor and ribosomal s6 kinases. 2003-10-02 2023-08-12 Not clear
D J Kwiatkowsk. Tuberous sclerosis: from tubers to mTOR. Annals of human genetics. vol 67. issue Pt 1. 2003-08-01. PMID:12556239. tuberous sclerosis: from tubers to mtor. 2003-08-01 2023-08-12 drosophila_melanogaster
Andrew R Tee, Diane C Fingar, Brendan D Manning, David J Kwiatkowski, Lewis C Cantley, John Bleni. Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 21. 2002-12-04. PMID:12271141. tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mtor)-mediated downstream signaling. 2002-12-04 2023-08-12 Not clear
Heidi L Kenerson, Lauri D Aicher, Lawrence D True, Raymond S Yeun. Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors. Cancer research. vol 62. issue 20. 2002-11-29. PMID:12384518. here we demonstrate that primary tumors from tuberous sclerosis complex (tsc) patients and the eker rat model of tsc expressed elevated levels of phosphorylated mammalian target of rapamycin (mtor) and its effectors: p70s6k, s6 ribosomal protein, 4e-bp1, and eif4g. 2002-11-29 2023-08-12 rat
Anja Jaeschke, Joerg Hartkamp, Masao Saitoh, Wendy Roworth, Takahiro Nobukuni, Angela Hodges, Julian Sampson, George Thomas, Richard Lam. Tuberous sclerosis complex tumor suppressor-mediated S6 kinase inhibition by phosphatidylinositide-3-OH kinase is mTOR independent. The Journal of cell biology. vol 159. issue 2. 2002-11-22. PMID:12403809. tuberous sclerosis complex tumor suppressor-mediated s6 kinase inhibition by phosphatidylinositide-3-oh kinase is mtor independent. 2002-11-22 2023-08-12 drosophila_melanogaster