| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Peng Liu, Xinmiao Xue, Chi Zhang, Hanwen Zhou, Zhiwei Ding, Li Wang, Yuke Jiang, Zhixin Zhang, Weidong Shen, Shiming Yang, Fangyuan Wan. Mid-Infrared Photons Alleviate Tinnitus by Activating the KCNQ2 Channel in the Auditory Cortex. Research (Washington, D.C.). vol 7. 2024-09-19. PMID:39296986. |
dysfunction of kcnq2 and kcnq3 channels-voltage-dependent potassium ion channels-in the cochlear nucleus can cause tinnitus. |
2024-09-19 |
2024-09-21 |
Not clear |
| Xinmiao Xue, Peng Liu, Chi Zhang, Zhiwei Ding, Li Wang, Yuke Jiang, Wei-Dong Shen, Shiming Yang, Fangyuan Wan. Transcriptional profile changes caused by noise-induced tinnitus in the cochlear nucleus and inferior colliculus of the rat. Annals of medicine. vol 56. issue 1. 2024-09-13. PMID:39268590. |
transcriptional profile changes caused by noise-induced tinnitus in the cochlear nucleus and inferior colliculus of the rat. |
2024-09-13 |
2024-09-18 |
rat |
| Johann Gross, Marlies Knipper, Birgit Mazure. Candidate Key Proteins in Tinnitus-A Bioinformatic Study of Synaptic Transmission in the Cochlear Nucleus. Biomedicines. vol 12. issue 7. 2024-07-27. PMID:39062188. |
a gene list was compiled from the genecards database using the keywords "synaptic transmission" and "tinnitus" and "cochlear nucleus" (tin). |
2024-07-27 |
2024-07-29 |
Not clear |
| Ch Kuhlmann, W Scheidemann, M Bachmann, G F Schusse. [Brainstem auditory evoked responses in horses with hearing loss and during general anesthesia]. Schweizer Archiv fur Tierheilkunde. vol 166. issue 7. 2024-07-08. PMID:38975650. |
horses with right sided external otitis: right moderate to severe conductive hearing loss (significantly prolonged latencies of i, iii, v and interpeak latencies i-iii, i-v, iii-v; thresholds of hearing levels 60 to 80 db right); horses with left sided external otitis: left severe conductive hearing loss (no correct identification of baer peaks, latencies not measurable, 80 db); horse with left sided head trauma: severe left sided conductive hearing loss (blood in the left external ear canal, no visible tympanic membrane, no correct identification of baer peaks, latencies not measurable, 80 db); horses with head shaking: mild sensorineural hearing loss on both sides (on both sides osseous parts ii/iii with keratin scales of the junction, visible tympanic membranes, significantly prolonged v, i-iii, i-v, 40 db); moderate to severe skittish horses with chronic eye disease (mostly left sided equine recurrent uveitis): moderate sensorineural hearing loss on both sides (normal otoscopical findings, significantly prolonged latencies and interpeak latencies left; i-v, iii-v right, 60 db, pathological involvement in the auditory pathway of the brainstem between the cochlear nucleus and colliculus caudalis); horse with a tinnitus on both sides: mild sensorineural hearing loss on both sides (normal otoscopical findings, prolonged v, i-iii, i-v, iii-v, 40 db, pathology of auditory nerve, cochlear nucleus and above the level of this nucleus); american paint horses: sensorineurale deafness on both sides (normal otoscopical findings, absent baer peaks, isoelectric lines and 80 db on both sides). |
2024-07-08 |
2024-07-11 |
Not clear |
| Mark P Pressler, Brian Brenner, Lynn R Kohan, Andrew M Mendelso. New-Onset Tinnitus After Dorsal Root Ganglion Stimulator Implantation: A Case Report. A&A practice. vol 18. issue 3. 2024-02-28. PMID:38416112. |
tinnitus can be modulated by secondary somatosensory inputs to the cochlear nucleus from the dcscs. |
2024-02-28 |
2024-03-01 |
Not clear |
| Vishweshwara Bhat, Emmanuel Shan Onaivi, Venkatanarayanan Sharm. Endocannabinoid system components as potential neuroimmune therapeutic targets in tinnitus. Frontiers in neurology. vol 14. 2023-06-12. PMID:37305742. |
tinnitus is believed to be a form of sensory epilepsy, spawning neuronal hyperactivity from the cochlear nucleus and inferior colliculus of the auditory brainstem region. |
2023-06-12 |
2023-08-14 |
Not clear |
| Min Chen, Shiyao Min, Chen Zhang, Xuerui Hu, Shufeng L. Using Extracochlear Multichannel Electrical Stimulation to Relieve Tinnitus and Reverse Tinnitus-Related Auditory-Somatosensory Plasticity in the Cochlear Nucleus. Neuromodulation : journal of the International Neuromodulation Society. 2021-08-04. PMID:34346133. |
using extracochlear multichannel electrical stimulation to relieve tinnitus and reverse tinnitus-related auditory-somatosensory plasticity in the cochlear nucleus. |
2021-08-04 |
2023-08-13 |
Not clear |
| Min Chen, Shiyao Min, Chen Zhang, Xuerui Hu, Shufeng L. Using Extracochlear Multichannel Electrical Stimulation to Relieve Tinnitus and Reverse Tinnitus-Related Auditory-Somatosensory Plasticity in the Cochlear Nucleus. Neuromodulation : journal of the International Neuromodulation Society. 2021-08-04. PMID:34346133. |
this study was to investigate whether a novel extracochlear electrical stimulation (ees) strategy could relieve tinnitus of guinea pigs without hearing impairment, and the roles of auditory-somatosensory plasticity in the cochlear nucleus in the tinnitus relief. |
2021-08-04 |
2023-08-13 |
Not clear |
| Peethambaran Arun, Franco Rossetti, Donna M Wilder, Ying Wang, Irene D Gist, Joseph B Lon. Blast Exposure Causes Long-Term Degeneration of Neuronal Cytoskeletal Elements in the Cochlear Nucleus: A Potential Mechanism for Chronic Auditory Dysfunctions. Frontiers in neurology. vol 12. 2021-04-13. PMID:33841318. |
the localized degeneration of neuronal cytoskeletal elements in the cochlear nucleus suggests that the damage could be caused by transmission of blast shockwaves/noise through the ear canal and that use of suitable ear protection devices can protect against acute and chronic central auditory signal processing defects including tinnitus after blast exposure. |
2021-04-13 |
2023-08-13 |
rat |
| Michelle R Kapolowicz, Lucien T Thompso. Plasticity in Limbic Regions at Early Time Points in Experimental Models of Tinnitus. Frontiers in systems neuroscience. vol 13. 2021-03-20. PMID:32038184. |
the pathology of tinnitus has been mechanistically linked to induction of harmful neural plasticity stemming from traumatic noise exposure, exposure to ototoxic medications, input deprivation from age-related hearing loss, and in response to injuries or disorders damaging the conductive apparatus of the ears, the cochlear hair cells, the ganglionic cells of the viiith cranial nerve, or neurons of the classical auditory pathway which link the cochlear nuclei through the inferior colliculi and medial geniculate nuclei to auditory cortices. |
2021-03-20 |
2023-08-13 |
human |
| Manli Yin, Chenchen Xia, Cong Wu, Yonghua Ji, You Zho. Aberrant expression of Nav1.6 in the cochlear nucleus correlates with salicylate-induced tinnitus in rats. Biochemical and biophysical research communications. vol 526. issue 3. 2020-12-17. PMID:32268959. |
aberrant expression of nav1.6 in the cochlear nucleus correlates with salicylate-induced tinnitus in rats. |
2020-12-17 |
2023-08-13 |
rat |
| Tang-Chuan Wang, Ta-Yuan Chang, Richard Tyler, Ying-Ju Lin, Wen-Miin Liang, Yio-Wha Shau, Wei-Yong Lin, Yi-Wen Chen, Chia-Der Lin, Ming-Hsui Tsa. Noise Induced Hearing Loss and Tinnitus-New Research Developments and Remaining Gaps in Disease Assessment, Treatment, and Prevention. Brain sciences. vol 10. issue 10. 2020-11-03. PMID:33066210. |
we discuss the mechanisms and maladaptive plasticity of nihl, neuronal aspects of tinnitus triggers, and mechanisms such as tinnitus-associated neural changes at the cochlear nucleus underlying the generation of tinnitus after noise-induced deafferentation. |
2020-11-03 |
2023-08-13 |
Not clear |
| Yonghua Ji, You Zho. Corrigendum to "Aberrant expression of Nav1.6 in the cochlear nucleus correlates with salicylate-induced tinnitus in rats" [Biochem. Biophys. Res. Commun. 526 (3) (2020) 786-792]. Biochemical and biophysical research communications. vol 527. issue 4. 2020-09-17. PMID:32456795. |
corrigendum to "aberrant expression of nav1.6 in the cochlear nucleus correlates with salicylate-induced tinnitus in rats" [biochem. |
2020-09-17 |
2023-08-13 |
rat |
| Heather Woo. Sensory systems: Bimodal cochlear nucleus stimulation alleviates tinnitus. Nature reviews. Neurology. vol 14. issue 3. 2019-08-22. PMID:29348542. |
sensory systems: bimodal cochlear nucleus stimulation alleviates tinnitus. |
2019-08-22 |
2023-08-13 |
Not clear |
| Amarins N Heeringa, Calvin Wu, Christopher Chung, Michael West, David Martel, Leslie Liberman, M Charles Liberman, Susan E Shor. Glutamatergic Projections to the Cochlear Nucleus are Redistributed in Tinnitus. Neuroscience. vol 391. 2019-02-27. PMID:30236972. |
glutamatergic projections to the cochlear nucleus are redistributed in tinnitus. |
2019-02-27 |
2023-08-13 |
Not clear |
| Thomas Brozoski, Daniel Brozoski, Kurt Wisner, Carol Baue. Chronic tinnitus and unipolar brush cell alterations in the cerebellum and dorsal cochlear nucleus. Hearing research. vol 350. 2018-04-02. PMID:28478300. |
neuron degeneration was also documented in the cochlear nucleus and pfl of exposed animals, both with and without tinnitus. |
2018-04-02 |
2023-08-13 |
rat |
| Paul F Smith, Yiwen Zhen. Cannabinoids, cannabinoid receptors and tinnitus. Hearing research. vol 332. 2016-12-13. PMID:26433054. |
one hypothesis suggests that tinnitus is a form of sensory epilepsy, arising partly from neuronal hyperactivity in auditory regions of the brain such as the cochlear nucleus and inferior colliculus. |
2016-12-13 |
2023-08-13 |
Not clear |
| Paul F Smith, Yiwen Zhen. Cannabinoids, cannabinoid receptors and tinnitus. Hearing research. vol 332. 2016-12-13. PMID:26433054. |
this review explores the question of whether cannabinoid receptor agonists are likely to be pro- or anti-epileptic in the cochlear nucleus and therefore whether cannabinoids and cannabis itself are likely to make tinnitus better or worse. |
2016-12-13 |
2023-08-13 |
Not clear |
| Yiwen Zheng, Kate McPherson, Peter Reid, Paul F Smit. The anti-inflammatory selective melanocortin receptor subtype 4 agonist, RO27-3225, fails to prevent acoustic trauma-induced tinnitus in rats. European journal of pharmacology. vol 761. 2016-05-17. PMID:25977231. |
in preliminary studies we have observed a massive microglial activation in the cochlear nucleus following acoustic trauma-induced tinnitus in rats, which suggests that inflammatory responses within the central auditory system may be involved in the development and maintenance of tinnitus. |
2016-05-17 |
2023-08-13 |
mouse |
| Jian-yu Dai, Yi-guo Chen, Xiao-qing Zhan. [The Impact of Electroacupuncture Intervention on Expression of 5-HTR 1 B/2 C Genes in Mice under Radiation Stimulation from Mobile Phone]. Zhen ci yan jiu = Acupuncture research. vol 40. issue 4. 2015-12-22. PMID:26502543. |
to observe the effect of electroacupuncture (ea) stimulation of "yifen" (te 17), "shenshu" (bl 23) on the expression of 5-hydroxytryptamine receptor 1 b (5-htr 1 b) mrna and 5-hydroxytryptamine receptor 2 c (5-htr 2 c) mrna in the cochlear nucleus tissue in mice experiencing radiation from mobile phone, so as to explore its mechanisms underlying improvement of tinnitus. |
2015-12-22 |
2023-08-13 |
mouse |