| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Benedikt Hofmeier, Stephan Wolpert, Ebrahim Saad Aldamer, Moritz Walter, John Thiericke, Christoph Braun, Dennis Zelle, Lukas Rüttiger, Uwe Klose, Marlies Knippe. Reduced sound-evoked and resting-state BOLD fMRI connectivity in tinnitus. NeuroImage. Clinical. vol 20. 2019-01-18. PMID:30202725. |
the finding went hand-in-hand with the emotional (amygdala, anterior insula) and temporofrontal/stress-regulating regions (prefrontal cortex, inferior frontal gyrus) that were no longer positively connected with auditory cortex regions in the tinnitus group but were instead positively connected to lower-level auditory brainstem regions. |
2019-01-18 |
2023-08-13 |
human |
| Timothy Olsen, Alberto Capurro, Nadia Pilati, Charles H Large, Martine Haman. Kv3 K Neuropharmacology. vol 133. 2018-11-05. PMID:29421326. |
kv3 k exposure to loud sound increases burst-firing of dorsal cochlear nucleus (dcn) fusiform cells in the auditory brainstem, which has been suggested to be an electrophysiological correlate of tinnitus. |
2018-11-05 |
2023-08-13 |
Not clear |
| Bo Gyung Kim, Takeshi Fujita, Konstantina M Stankovic, D Bradley Welling, In Seok Moon, Jae Young Choi, Jieun Yun, Jong Soon Kang, Jong Dae Le. Sulforaphane, a natural component of broccoli, inhibits vestibular schwannoma growth in vitro and in vivo. Scientific reports. vol 6. 2018-05-22. PMID:27805058. |
vestibular schwannoma (vs) is an intracranial tumor that causes significant morbidity, including hearing loss, tinnitus, dizziness, and possibly even death from brainstem compression. |
2018-05-22 |
2023-08-13 |
human |
| Jinsheng Zhang, Hao Luo, Edward Pace, Liang Li, Bin Li. Psychophysical and neural correlates of noised-induced tinnitus in animals: Intra- and inter-auditory and non-auditory brain structure studies. Hearing research. vol 334. 2018-01-08. PMID:26299842. |
the manner in which fli appeared suggests that lower brainstem structures may be involved in acute tinnitus whereas the midbrain and cortex are involved in more chronic tinnitus. |
2018-01-08 |
2023-08-13 |
rat |
| Jeremy G Turner, Deb Larse. Effects of noise exposure on development of tinnitus and hyperacusis: Prevalence rates 12 months after exposure in middle-aged rats. Hearing research. vol 334. 2018-01-08. PMID:26584761. |
12-mo after noise exposure the middle-aged rats were then tested again for tinnitus and hyperacusis before collecting auditory brainstem response (abr) thresholds. |
2018-01-08 |
2023-08-13 |
rat |
| Hyun Joon Shim, Yong-Hwi An, Dong Hyun Kim, Ji Eun Yoon, Ji Hyang Yoo. Comparisons of auditory brainstem response and sound level tolerance in tinnitus ears and non-tinnitus ears in unilateral tinnitus patients with normal audiograms. PloS one. vol 12. issue 12. 2018-01-08. PMID:29253030. |
comparisons of auditory brainstem response and sound level tolerance in tinnitus ears and non-tinnitus ears in unilateral tinnitus patients with normal audiograms. |
2018-01-08 |
2023-08-13 |
human |
| Hyun Joon Shim, Yong-Hwi An, Dong Hyun Kim, Ji Eun Yoon, Ji Hyang Yoo. Comparisons of auditory brainstem response and sound level tolerance in tinnitus ears and non-tinnitus ears in unilateral tinnitus patients with normal audiograms. PloS one. vol 12. issue 12. 2018-01-08. PMID:29253030. |
several studies have demonstrated that subjects with tinnitus and normal audiograms show significantly reduced auditory brainstem response (abr) wave i amplitudes compared with control subjects, but normal wave v amplitudes, suggesting increased central auditory gain. |
2018-01-08 |
2023-08-13 |
human |
| Sherifa A Hame. The auditory and vestibular toxicities induced by antiepileptic drugs. Expert opinion on drug safety. vol 16. issue 11. 2017-10-23. PMID:28838247. |
carbamazepine, phenytoin, valproate, lamotrigine, gabapentin, vigabatrin and oxcarbazepine] (even in therapeutic drug doses) may result in tinnitus, phonophobia, sensorineural hearing loss, dizziness, ataxia, disequilibrium, imbalance, nystagmus, abnormalities in saccadic and pursuit eye movements and delayed conduction within the cochlea, auditory nerve and brainstem auditory pathways evidenced by abnormalities in brainstem auditory evoked potentials and nystagmography recordings indicating auditory and central and/or peripheral vestibular dysfunctions. |
2017-10-23 |
2023-08-13 |
Not clear |
| Juen-Haur Hwang, Yin-Ching Cha. Expression of Dopamine Receptor 1A and Cannabinoid Receptor 1 Genes in the Cochlea and Brain after Salicylate-Induced Tinnitus. ORL; journal for oto-rhino-laryngology and its related specialties. vol 78. issue 5. 2017-10-18. PMID:27658122. |
the results showed that 4-day salicylate treatment (unlike 4-day saline treatment) caused a significant increase in the tinnitus score and in mrna expression of the dr1a gene in the cochlea, the brainstem and inferior colliculus, the hippocampus and parahippocampus, and the temporal lobe, but not the frontal lobe. |
2017-10-18 |
2023-08-13 |
mouse |
| Daniel S Roberts, Steve Otto, Brian Chen, Kevin A Peng, Marc S Schwartz, Derald E Brackmann, John W Hous. Tinnitus Suppression After Auditory Brainstem Implantation in Patients With Neurofibromatosis Type-2. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. vol 38. issue 1. 2017-09-08. PMID:27755361. |
tinnitus suppression after auditory brainstem implantation in patients with neurofibromatosis type-2. |
2017-09-08 |
2023-08-13 |
Not clear |
| Daniel S Roberts, Steve Otto, Brian Chen, Kevin A Peng, Marc S Schwartz, Derald E Brackmann, John W Hous. Tinnitus Suppression After Auditory Brainstem Implantation in Patients With Neurofibromatosis Type-2. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. vol 38. issue 1. 2017-09-08. PMID:27755361. |
to evaluate whether an auditory brainstem implant (abi) can impact levels of tinnitus in neurofibromatosis type-2 (nf2) patients who have undergone translabyrinthine craniotomy for vestibular schwannoma (vs) removal and to evaluate the burden of tinnitus in these patients. |
2017-09-08 |
2023-08-13 |
Not clear |
| Thomas Tagoe, Daniel Deeping, Martine Haman. Saturation of long-term potentiation in the dorsal cochlear nucleus and its pharmacological reversal in an experimental model of tinnitus. Experimental neurology. vol 292. 2017-07-28. PMID:28214516. |
animal models have demonstrated that tinnitus is a pathology of dysfunctional excitability in the central auditory system, in particular in the dorsal cochlear nucleus (dcn) of the brainstem. |
2017-07-28 |
2023-08-13 |
Not clear |
| Thomas Tagoe, Daniel Deeping, Martine Haman. Saturation of long-term potentiation in the dorsal cochlear nucleus and its pharmacological reversal in an experimental model of tinnitus. Experimental neurology. vol 292. 2017-07-28. PMID:28214516. |
shifts in hearing threshold were quantified by auditory brainstem recordings, and gap-induced prepulse inhibition of the acoustic startle reflex was used as an index for tinnitus. |
2017-07-28 |
2023-08-13 |
Not clear |
| Tomomi Okamura, Takafumi Nishizaki, Norio Ikeda, Shigeki Nakano, Takanori Sakakura, Natsumi Fujii, Takeshi Okud. [Diagnosis of Cochleovestibular Neurovascular Compression Syndrome:A Scoring System Based on Five Clinical Characteristics]. No shinkei geka. Neurological surgery. vol 45. issue 2. 2017-06-22. PMID:28202828. |
the following five clinical features were evaluated and given a score of 1 or 0:1)a long history of recurrent vertigo, tinnitus, or hearing loss;2)neurological findings related to positional vertigo, nystagmus, tinnitus, or hearing loss;3)neuro-otological findings involving tinnitus, audiometry, or vestibular testing;4)auditory brainstem response(abr)evaluation with the detection of a low 25-75% ii wave amplitude on the contralateral side and delayed interpeak latency in the i-iii or i-v waves(usually low ii wave amplitude combined with double peaks and a wide-based form)during abr evaluation using 80 and 90db clicks;and 5)the detection of vascular contact with the eighth cranial nerve on magnetic resonance imaging-constructive interference in steady state or air computed tomography imaging. |
2017-06-22 |
2023-08-13 |
Not clear |
| Songbai Yang, Zhigang Mei, Lingjing Tan, Wenhan Ma, Dingqi Zhang, Zhaojun Wang, Tiantian Li, Kunyan Huang, Sanjin Ca. [Effects of electrical stimulation at acupoints in the distribution area of auricular vagus nerve combined with sound masking method on auditory brainstem response and neurotransmitters of inferior colliculus in rats of tinnitus]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 36. issue 5. 2016-09-22. PMID:27509615. |
[effects of electrical stimulation at acupoints in the distribution area of auricular vagus nerve combined with sound masking method on auditory brainstem response and neurotransmitters of inferior colliculus in rats of tinnitus]. |
2016-09-22 |
2023-08-13 |
rat |
| Songbai Yang, Zhigang Mei, Lingjing Tan, Wenhan Ma, Dingqi Zhang, Zhaojun Wang, Tiantian Li, Kunyan Huang, Sanjin Ca. [Effects of electrical stimulation at acupoints in the distribution area of auricular vagus nerve combined with sound masking method on auditory brainstem response and neurotransmitters of inferior colliculus in rats of tinnitus]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 36. issue 5. 2016-09-22. PMID:27509615. |
to explore the effects of electrical stimulation at acupoints in the distribution area of auricular vagus nerve combined with sound masking on auditory brainstem response (abr) and contents of neurotransmitters of γ-aminobutyric acid (γ-gaba), 5-hydroxytryptamine (5-ht) and acetyl choline (ach) in inferior colliculus of tinnitus rats. |
2016-09-22 |
2023-08-13 |
rat |
| Iman Ghodratitoostani, Yossi Zana, Alexandre C B Delbem, Siamak S Sani, Hamed Ekhtiari, Tanit G Sanche. Theoretical Tinnitus Framework: A Neurofunctional Model. Frontiers in neuroscience. vol 10. 2016-09-05. PMID:27594822. |
structurally, the neurofunctional tinnitus model includes the peripheral auditory system, the thalamus, the limbic system, brainstem, basal ganglia, striatum, and the auditory along with prefrontal cortices. |
2016-09-05 |
2023-08-13 |
Not clear |
| Calvin Wu, David T Martel, Susan E Shor. Increased Synchrony and Bursting of Dorsal Cochlear Nucleus Fusiform Cells Correlate with Tinnitus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 6. 2016-07-01. PMID:26865628. |
the presence of increased synchrony and bursting in dcn fusiform cells suggests that a neural code for phantom sounds emerges in this brainstem location and likely contributes to the formation of the tinnitus percept. |
2016-07-01 |
2023-08-13 |
Not clear |
| Edward Lobarinas, Caroline Blair, Christopher Spankovich, Colleen Le Prel. Partial to complete suppression of unilateral noise-induced tinnitus in rats after cyclobenzaprine treatment. Journal of the Association for Research in Otolaryngology : JARO. vol 16. issue 2. 2016-05-10. PMID:25526855. |
one central site that could be related to tinnitus awareness or modulation is the locus coeruleus, a brainstem structure associated with stress, arousal, and attention. |
2016-05-10 |
2023-08-13 |
rat |
| Charu Singh, Rahul Kawatra, Jaya Gupta, Vishnu Awasthi, Homnath Dungan. Therapeutic role of Vitamin B12 in patients of chronic tinnitus: A pilot study. Noise & health. vol 18. issue 81. 2016-05-05. PMID:26960786. |
true tinnitus is a phantom auditory perception arising from a source or trigger in the cochlea, brainstem, or at higher centers and has no detectable acoustic generator. |
2016-05-05 |
2023-08-13 |
Not clear |