| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yinghua Jiang, Ning Liu, Qingzhi Wang, Zhanyang Yu, Li Lin, Jing Yuan, Shuzhen Guo, Bum Ju Ahn, Xiao-Jie Wang, Xiaokun Li, Eng H Lo, Xiaochuan Sun, Xiaoying Wan. Endocrine Regulator rFGF21 (Recombinant Human Fibroblast Growth Factor 21) Improves Neurological Outcomes Following Focal Ischemic Stroke of Type 2 Diabetes Mellitus Male Mice. Stroke. vol 49. issue 12. 2019-10-07. PMID:30571410. |
methods- type 2 diabetes mellitus db/db and nondiabetic genetic control db/+ mice were subjected into permanent focal ischemia of distal middle cerebral artery occlusion, we examined the effects of poststroke administration with rfgf21 in systemic metabolic disorders, inflammatory gatekeeper pparγ (peroxisome proliferator-activated receptor γ) activity at 3 days, mrna expression of inflammatory cytokines and microglia/macrophage activation at 7 days in the perilesion cortex, and last neurological function deficits, ischemic brain infarction, and white matter integrity up to 14 days after stroke of db/db mice. |
2019-10-07 |
2023-08-13 |
mouse |
| Timal S Kannangara, Anthony Carter, Yingben Xue, Jagroop S Dhaliwal, Jean-Claude Béïque, Diane C Lagac. Excitable Adult-Generated GABAergic Neurons Acquire Functional Innervation in the Cortex after Stroke. Stem cell reports. vol 11. issue 6. 2019-09-20. PMID:30416050. |
excitable adult-generated gabaergic neurons acquire functional innervation in the cortex after stroke. |
2019-09-20 |
2023-08-13 |
mouse |
| Timal S Kannangara, Anthony Carter, Yingben Xue, Jagroop S Dhaliwal, Jean-Claude Béïque, Diane C Lagac. Excitable Adult-Generated GABAergic Neurons Acquire Functional Innervation in the Cortex after Stroke. Stem cell reports. vol 11. issue 6. 2019-09-20. PMID:30416050. |
studies have correlated precursor cell proliferation and subsequent adult neurogenesis with enhanced stroke recovery, yet it remains unclear whether stroke can generate new neurons capable of functional integration into the injured cortex. |
2019-09-20 |
2023-08-13 |
mouse |
| Timal S Kannangara, Anthony Carter, Yingben Xue, Jagroop S Dhaliwal, Jean-Claude Béïque, Diane C Lagac. Excitable Adult-Generated GABAergic Neurons Acquire Functional Innervation in the Cortex after Stroke. Stem cell reports. vol 11. issue 6. 2019-09-20. PMID:30416050. |
collectively, these findings reveal that gabaergic neurons arising from the lateral ventricle have the capacity to integrate into the stroke-injured cortex, although their limited number and exiguous synaptic integration may limit their ability to participate in stroke recovery. |
2019-09-20 |
2023-08-13 |
mouse |
| Bojana Kokinovic, Paolo Medin. Loss of GABA The Journal of physiology. vol 596. issue 10. 2019-09-09. PMID:29508394. |
in a focal model of stroke in mouse somatosensory cortex, we found that the recovery of sensory responsiveness occurs at the level of synaptic inputs, without gross changes of the intrinsic electrical excitability of neurons, and also that recovered responses had longer than normal latencies. |
2019-09-09 |
2023-08-13 |
mouse |
| Michael K Schuhmann, Guido Stoll, Arne Bohr, Jens Volkmann, Felix Flur. Electrical Stimulation of the Mesencephalic Locomotor Region Attenuates Neuronal Loss and Cytokine Expression in the Perifocal Region of Photothrombotic Stroke in Rats. International journal of molecular sciences. vol 20. issue 9. 2019-09-03. PMID:31083528. |
rats underwent photothrombotic stroke of the right sensorimotor cortex and the implantation of a microelectrode into the ipsilesional mlr. |
2019-09-03 |
2023-08-13 |
rat |
| Minying Li, Lin Wang, Nenggui Xu, Xiaorong Tang, Mindong Xu, Jianhua Liu, Jianpeng Huang, Judith M Schlaege. Effect of electro-acupuncture on lateralization of the human swallowing motor cortex excitability in healthy subjects: study protocol for a single-blind, randomized controlled trial. Trials. vol 20. issue 1. 2019-08-05. PMID:30898173. |
the purpose of this study is to investigate whether lateralization of the human swallowing motor cortex excitability in healthy subjects will be influenced by electro-acupuncture to lianquan (cv 23) and fengfu (gv 16), which may provide insight into the pathological mechanisms of dysphagia after stroke. |
2019-08-05 |
2023-08-13 |
human |
| Kahlilia C Morris-Blanco, TaeHee Kim, Mario J Bertogliat, Suresh L Mehta, Anil K Chokkalla, Raghu Vemugant. Inhibition of the Epigenetic Regulator REST Ameliorates Ischemic Brain Injury. Molecular neurobiology. vol 56. issue 4. 2019-08-02. PMID:30039336. |
these results demonstrate that direct inhibition of the epigenetic remodeler rest prevents secondary brain damage in the cortex and improves functional outcome potentially via de-repression of plasticity-related genes after stroke. |
2019-08-02 |
2023-08-13 |
rat |
| Erik van Tilborg, Caren M van Kammen, Caroline G M de Theije, Maurits P A van Meer, Rick M Dijkhuizen, Cora H Nijboe. A quantitative method for microstructural analysis of myelinated axons in the injured rodent brain. Scientific reports. vol 7. issue 1. 2019-07-12. PMID:29184182. |
to validate these methods, we carefully analyzed the organization of myelinated axons running from the external capsule towards the outer layers of the cortex in three rodent models of neonatal brain injury and in an adult stroke model, that have all been associated with myelination impairments. |
2019-07-12 |
2023-08-13 |
Not clear |
| Hiroshi Nagahama, Masahito Nakazaki, Masanori Sasaki, Yuko Kataoka-Sasaki, Takahiro Namioka, Ai Namioka, Shinichi Oka, Rie Onodera, Junpei Suzuki, Yuichi Sasaki, Jeffery D Kocsis, Osamu Honmo. Preservation of interhemispheric cortical connections through corpus callosum following intravenous infusion of mesenchymal stem cells in a rat model of cerebral infarction. Brain research. vol 1695. 2019-07-11. PMID:29802840. |
this anatomical preservation of the motor cortex in the contralateral hemisphere may contribute to functional improvements following msc therapy for cerebral stroke. |
2019-07-11 |
2023-08-13 |
rat |
| Huifang Xiang, Jing Sun, Xiang Tang, Kebin Zeng, Xiushu W. The effect and optimal parameters of repetitive transcranial magnetic stimulation on motor recovery in stroke patients: a systematic review and meta-analysis of randomized controlled trials. Clinical rehabilitation. vol 33. issue 5. 2019-07-10. PMID:30773896. |
the primary aim of this meta-analysis was to evaluate the effects of repetitive transcranial magnetic stimulation (rtms) on limb movement recovery post-stroke and cortex excitability, to explore the optimal parameters of rtms and suitable stroke population. |
2019-07-10 |
2023-08-13 |
Not clear |
| Jennifer K Ferris, Sue Peters, Katlyn E Brown, Katherine Tourigny, Lara A Boy. Type-2 diabetes mellitus reduces cortical thickness and decreases oxidative metabolism in sensorimotor regions after stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 38. issue 5. 2019-05-21. PMID:28401788. |
here, we considered how type-2 diabetes impacted the structural and metabolic function of the sensorimotor cortex after stroke using volumetric magnetic resonance imaging (mri) and magnetic resonance spectroscopy (mrs). |
2019-05-21 |
2023-08-13 |
Not clear |
| Jennifer K Ferris, Sue Peters, Katlyn E Brown, Katherine Tourigny, Lara A Boy. Type-2 diabetes mellitus reduces cortical thickness and decreases oxidative metabolism in sensorimotor regions after stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 38. issue 5. 2019-05-21. PMID:28401788. |
we hypothesized that the combination of chronic stroke and type-2 diabetes would negatively impact the integrity of sensorimotor cortex as compared to individuals with chronic stroke alone. |
2019-05-21 |
2023-08-13 |
Not clear |
| Jennifer K Ferris, Sue Peters, Katlyn E Brown, Katherine Tourigny, Lara A Boy. Type-2 diabetes mellitus reduces cortical thickness and decreases oxidative metabolism in sensorimotor regions after stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 38. issue 5. 2019-05-21. PMID:28401788. |
individuals with stroke and diabetes also showed reduced creatine levels bilaterally in the sensorimotor cortex. |
2019-05-21 |
2023-08-13 |
Not clear |
| Jennifer K Ferris, Sue Peters, Katlyn E Brown, Katherine Tourigny, Lara A Boy. Type-2 diabetes mellitus reduces cortical thickness and decreases oxidative metabolism in sensorimotor regions after stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 38. issue 5. 2019-05-21. PMID:28401788. |
contralesional primary and secondary motor cortex thicknesses were negatively related to sensorimotor outcomes in the paretic upper-limb in the stroke and diabetes group such that those with thinner primary and secondary motor cortices had better motor function. |
2019-05-21 |
2023-08-13 |
Not clear |
| Jennifer K Ferris, Sue Peters, Katlyn E Brown, Katherine Tourigny, Lara A Boy. Type-2 diabetes mellitus reduces cortical thickness and decreases oxidative metabolism in sensorimotor regions after stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 38. issue 5. 2019-05-21. PMID:28401788. |
these data suggest that type-2 diabetes alters cerebral energy metabolism, and is associated with thinning of sensorimotor cortex after stroke. |
2019-05-21 |
2023-08-13 |
Not clear |
| Brenton Hordacre, Bahar Moezzi, Michael C Riddin. Neuroplasticity and network connectivity of the motor cortex following stroke: A transcranial direct current stimulation study. Human brain mapping. vol 39. issue 8. 2019-05-21. PMID:29655257. |
neuroplasticity and network connectivity of the motor cortex following stroke: a transcranial direct current stimulation study. |
2019-05-21 |
2023-08-13 |
Not clear |
| Dhakshin S Ramanathan, Ling Guo, Tanuj Gulati, Gray Davidson, April K Hishinuma, Seok-Joon Won, Robert T Knight, Edward F Chang, Raymond A Swanson, Karunesh Gangul. Low-frequency cortical activity is a neuromodulatory target that tracks recovery after stroke. Nature medicine. vol 24. issue 8. 2019-05-10. PMID:29915259. |
in rodents, we found that reach-related lfos, as measured in both the local field potential and the related spiking activity, were diminished after stroke and that spontaneous recovery was closely correlated with their restoration in the perilesional cortex. |
2019-05-10 |
2023-08-13 |
human |
| Silun Wang, Yonggang Li, Ramesh Paudyal, Byron D Ford, Xiaodong Zhan. Evaluation of neuregulin-1's neuroprotection against ischemic injury in rats using diffusion tensor imaging. Magnetic resonance imaging. vol 53. 2019-04-22. PMID:30021123. |
as a conclusion, the present dti results demonstrate that nrg-1 has significantly neuroprotective effects in both cerebral cortex and white matter including corpus callosum and fornix during acute stroke. |
2019-04-22 |
2023-08-13 |
rat |
| V V Alferova, L A Mayorova, E G Ivanova, A B Guekht, V M Shklovski. [Functional neuroimaging of the brain structures associated with language in healthy individuals and patients with post-stroke aphasia]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 117. issue 3. Vyp. 2. 2019-04-05. PMID:28665373. |
the article discusses the results of fmri studies of functional organization of the cortex of a healthy adult's brain in the processing of various voice information as well as the main types of speech reorganization after post-stroke aphasia in different stroke periods. |
2019-04-05 |
2023-08-13 |
Not clear |