Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
D S Roberts, Y H Raol, S Bandyopadhyay, I V Lund, E C Budreck, M A Passini, M J Passini, J H Wolfe, A R Brooks-Kayal, S J Russe. Egr3 stimulation of GABRA4 promoter activity as a mechanism for seizure-induced up-regulation of GABA(A) receptor alpha4 subunit expression. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 33. 2005-10-25. PMID:16091474. |
given that egr3 knockout mice display approximately 50% less gabra4 mrnas in the hippocampus and that increases in alpha4 and egr3 mrnas in response to pilocarpine-induced status epilepticus are accompanied by increased binding of egr3 to gabra4 in dentate granule cells, our findings support a role for egr3 as a major regulator of gabra4 in developing neurons and in epilepsy. |
2005-10-25 |
2023-08-12 |
mouse |
H B Laurén, F R Lopez-Picon, E R Korpi, I E Holopaine. Kainic acid-induced status epilepticus alters GABA receptor subunit mRNA and protein expression in the developing rat hippocampus. Journal of neurochemistry. vol 94. issue 5. 2005-09-22. PMID:15992369. |
kainic acid-induced status epilepticus alters gaba receptor subunit mrna and protein expression in the developing rat hippocampus. |
2005-09-22 |
2023-08-12 |
rat |
H B Laurén, F R Lopez-Picon, E R Korpi, I E Holopaine. Kainic acid-induced status epilepticus alters GABA receptor subunit mRNA and protein expression in the developing rat hippocampus. Journal of neurochemistry. vol 94. issue 5. 2005-09-22. PMID:15992369. |
kainic acid-induced status epilepticus leads to structural and functional changes in inhibitory gabaa receptors in the adult rat hippocampus, but whether similar changes occur in the developing rat is not known. |
2005-09-22 |
2023-08-12 |
rat |
H B Laurén, F R Lopez-Picon, E R Korpi, I E Holopaine. Kainic acid-induced status epilepticus alters GABA receptor subunit mRNA and protein expression in the developing rat hippocampus. Journal of neurochemistry. vol 94. issue 5. 2005-09-22. PMID:15992369. |
our results show that status epilepticus disturbs the normal developmental expression pattern of gabaa receptor subunit in the rat hippocampus during the sensitive postnatal period of brain development. |
2005-09-22 |
2023-08-12 |
rat |
Maria Thom, Jiemin Zhou, Lillian Martinian, Sanjay Sisodiy. Quantitative post-mortem study of the hippocampus in chronic epilepsy: seizures do not inevitably cause neuronal loss. Brain : a journal of neurology. vol 128. issue Pt 6. 2005-09-13. PMID:15758032. |
early febrile seizures, episodes of status epilepticus as well as repetitive brief seizures may all contribute to the evolution of hippocampal sclerosis. |
2005-09-13 |
2023-08-12 |
human |
Maria Thom, Jiemin Zhou, Lillian Martinian, Sanjay Sisodiy. Quantitative post-mortem study of the hippocampus in chronic epilepsy: seizures do not inevitably cause neuronal loss. Brain : a journal of neurology. vol 128. issue Pt 6. 2005-09-13. PMID:15758032. |
post-mortem stereological analysis of 28 patients with poorly controlled seizures has confirmed a subgroup with absence of significant hippocampal neuronal loss despite decades of generalized seizures, including status epilepticus. |
2005-09-13 |
2023-08-12 |
human |
Xiaoying Lu, Andrey Mazarati, Pietro Sanna, Steve Shinmei, Tamas Bartfa. Distribution and differential regulation of galanin receptor subtypes in rat brain: effects of seizure activity. Neuropeptides. vol 39. issue 3. 2005-09-13. PMID:15944003. |
status epilepticus (se), known to deplete galanin from axonal projections of locus coeruleus and septum/diagonal band neurons in the hippocampus and to induce galanin expression in a subset of hippocampal cells, down regulates galr2 receptor mrna and proteins by 30% without altering the galr1 receptors. |
2005-09-13 |
2023-08-12 |
rat |
Andrey Mazarati, Xiaoying L. Regulation of limbic status epilepticus by hippocampal galanin type 1 and type 2 receptors. Neuropeptides. vol 39. issue 3. 2005-09-13. PMID:15944022. |
regulation of limbic status epilepticus by hippocampal galanin type 1 and type 2 receptors. |
2005-09-13 |
2023-08-12 |
mouse |
Teresa Ravizza, Massimo Rizzi, Carlo Perego, Cristina Richichi, Jana Velísková, Solomon L Moshé, M Grazia De Simoni, Annamaria Vezzan. Inflammatory response and glia activation in developing rat hippocampus after status epilepticus. Epilepsia. vol 46 Suppl 5. 2005-07-28. PMID:15987264. |
inflammatory response and glia activation in developing rat hippocampus after status epilepticus. |
2005-07-28 |
2023-08-12 |
rat |
Teresa Ravizza, Massimo Rizzi, Carlo Perego, Cristina Richichi, Jana Velísková, Solomon L Moshé, M Grazia De Simoni, Annamaria Vezzan. Inflammatory response and glia activation in developing rat hippocampus after status epilepticus. Epilepsia. vol 46 Suppl 5. 2005-07-28. PMID:15987264. |
we investigated the activation of microglia and astrocytes, induction of cytokines, and hippocampal neuronal damage, 4 and 24 h after kainic acid-induced status epilepticus (se) in postnatal day (pn) 9, 15, and 21 rats. |
2005-07-28 |
2023-08-12 |
rat |
Feng Ru Tang, Shwn Chin Chia, Si Zhang, Peng Min Chen, Hong Gao, Chun Ping Liu, Sanjay Khanna, Wei Ling Le. Glutamate receptor 1-immunopositive neurons in the gliotic CA1 area of the mouse hippocampus after pilocarpine-induced status epilepticus. The European journal of neuroscience. vol 21. issue 9. 2005-07-14. PMID:15932595. |
glutamate receptor 1-immunopositive neurons in the gliotic ca1 area of the mouse hippocampus after pilocarpine-induced status epilepticus. |
2005-07-14 |
2023-08-12 |
mouse |
Inês M Araújo, Sara Xapelli, Joana M A C Gil, Paul Mohapel, Asa Petersén, Paulo S Pinheiro, João O Malva, Ben A Bahr, Patrik Brundin, Caetana M Carvalh. Proteolysis of NR2B by calpain in the hippocampus of epileptic rats. Neuroreport. vol 16. issue 4. 2005-06-13. PMID:15729144. |
our results show that cleaved forms of nr2b subunits are formed after status epilepticus, in the same areas of the hippocampus where calpain activation was detected by immunohistochemical staining of calpain-specific spectrin breakdown products. |
2005-06-13 |
2023-08-12 |
rat |
Alexandre Valotta da Silva, Maria Cristina Regondi, Barbara Cipelletti, Carolina Frassoni, Esper Abrão Cavalheiro, Roberto Spreafic. Neocortical and hippocampal changes after multiple pilocarpine-induced status epilepticus in rats. Epilepsia. vol 46. issue 5. 2005-06-01. PMID:15857427. |
neocortical and hippocampal changes after multiple pilocarpine-induced status epilepticus in rats. |
2005-06-01 |
2023-08-12 |
rat |
M Niimura, R Moussa, N Bissoon, C Ikeda-Douglas, N W Milgram, J W Gur. Changes in phosphorylation of the NMDA receptor in the rat hippocampus induced by status epilepticus. Journal of neurochemistry. vol 92. issue 6. 2005-04-22. PMID:15748156. |
changes in phosphorylation of the nmda receptor in the rat hippocampus induced by status epilepticus. |
2005-04-22 |
2023-08-12 |
rat |
Rivelilson M Freitas, Silvânia M M Vasconcelos, Francisca C F Souza, Glauce S B Viana, Marta M F Fontele. Oxidative stress in the hippocampus after pilocarpine-induced status epilepticus in Wistar rats. The FEBS journal. vol 272. issue 6. 2005-04-18. PMID:15752349. |
oxidative stress in the hippocampus after pilocarpine-induced status epilepticus in wistar rats. |
2005-04-18 |
2023-08-12 |
rat |
Rivelilson M Freitas, Silvânia M M Vasconcelos, Francisca C F Souza, Glauce S B Viana, Marta M F Fontele. Oxidative stress in the hippocampus after pilocarpine-induced status epilepticus in Wistar rats. The FEBS journal. vol 272. issue 6. 2005-04-18. PMID:15752349. |
the role of oxidative stress in pilocarpine-induced status epilepticus was investigated by measuring lipid peroxidation level, nitrite content, gsh concentration, and superoxide dismutase and catalase activities in the hippocampus of wistar rats. |
2005-04-18 |
2023-08-12 |
rat |
Rivelilson M Freitas, Silvânia M M Vasconcelos, Francisca C F Souza, Glauce S B Viana, Marta M F Fontele. Oxidative stress in the hippocampus after pilocarpine-induced status epilepticus in Wistar rats. The FEBS journal. vol 272. issue 6. 2005-04-18. PMID:15752349. |
gsh and catalase activity are involved in mechanisms responsible for eliminating oxygen free radicals during the establishment of status epilepticus in the hippocampus. |
2005-04-18 |
2023-08-12 |
rat |
Rivelilson M Freitas, Silvânia M M Vasconcelos, Francisca C F Souza, Glauce S B Viana, Marta M F Fontele. Oxidative stress in the hippocampus after pilocarpine-induced status epilepticus in Wistar rats. The FEBS journal. vol 272. issue 6. 2005-04-18. PMID:15752349. |
our results suggest that gsh and catalase activity play an antioxidant role in the hippocampus during status epilepticus. |
2005-04-18 |
2023-08-12 |
rat |
Robert S Slovite. The neurobiology of temporal lobe epilepsy: too much information, not enough knowledge. Comptes rendus biologies. vol 328. issue 2. 2005-04-14. PMID:15771000. |
recent observations suggest that significant disparities exist between the features of human tle with hippocampal sclerosis and those of animal models that involve prolonged status epilepticus to initiate the epileptogenic process. |
2005-04-14 |
2023-08-12 |
human |
Robert S Slovite. The neurobiology of temporal lobe epilepsy: too much information, not enough knowledge. Comptes rendus biologies. vol 328. issue 2. 2005-04-14. PMID:15771000. |
in addition, although many tle patients exhibit an atrophic hippocampus that may, or may not, be a source of spontaneous seizures, hippocampal damage in animals subjected to status epilepticus is an inconsistent and often minor part of a much greater constellation of damage to other brain structures. |
2005-04-14 |
2023-08-12 |
human |