| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Moran, A Sanz-Rodriguez, A Jimenez-Pacheco, J Martinez-Villareal, R C McKiernan, E M Jimenez-Mateos, C Mooney, I Woods, J H M Prehn, D C Henshall, T Enge. Bmf upregulation through the AMP-activated protein kinase pathway may protect the brain from seizure-induced cell death. Cell death & disease. vol 4. 2013-10-23. PMID:23618904. |
prolonged seizures (status epilepticus, se) can cause neuronal death within brain regions such as the hippocampus. |
2013-10-23 |
2023-08-12 |
mouse |
| C Moran, A Sanz-Rodriguez, A Jimenez-Pacheco, J Martinez-Villareal, R C McKiernan, E M Jimenez-Mateos, C Mooney, I Woods, J H M Prehn, D C Henshall, T Enge. Bmf upregulation through the AMP-activated protein kinase pathway may protect the brain from seizure-induced cell death. Cell death & disease. vol 4. 2013-10-23. PMID:23618904. |
indeed, mice lacking certain members of the potently proapoptotic bh3-only subfamily of bcl-2 proteins are protected against hippocampal damage caused by status epilepticus. |
2013-10-23 |
2023-08-12 |
mouse |
| Zuzanna Michalak, Takanori Sano, Tobias Engel, Suzanne F C Miller-Delaney, Mireille Lerner-Natoli, David C Henshal. Spatio-temporally restricted blood-brain barrier disruption after intra-amygdala kainic acid-induced status epilepticus in mice. Epilepsy research. vol 103. issue 2-3. 2013-10-22. PMID:23182415. |
triggering status epilepticus in mice by intra-amygdala microinjection of kainic acid produces damage mainly within the ca3 subfield of the ipsilateral hippocampus, and recurrent spontaneous seizures emerge during the following week. |
2013-10-22 |
2023-08-12 |
mouse |
| Zuzanna Michalak, Takanori Sano, Tobias Engel, Suzanne F C Miller-Delaney, Mireille Lerner-Natoli, David C Henshal. Spatio-temporally restricted blood-brain barrier disruption after intra-amygdala kainic acid-induced status epilepticus in mice. Epilepsy research. vol 103. issue 2-3. 2013-10-22. PMID:23182415. |
to investigate whether bbb impairment is a feature of this model, we characterized endothelial tight cell junction proteins and igg and albumin in the hippocampus up to three weeks after status epilepticus. |
2013-10-22 |
2023-08-12 |
mouse |
| Zuzanna Michalak, Takanori Sano, Tobias Engel, Suzanne F C Miller-Delaney, Mireille Lerner-Natoli, David C Henshal. Spatio-temporally restricted blood-brain barrier disruption after intra-amygdala kainic acid-induced status epilepticus in mice. Epilepsy research. vol 103. issue 2-3. 2013-10-22. PMID:23182415. |
hippocampal microvessels displayed a reduction in continuous staining for zonula occludens 1 (zo-1), the main tight junction protein, after status epilepticus and in epileptic mice, although western blotting found zo-1 protein levels in the hippocampal subfields were not different from controls at any time. |
2013-10-22 |
2023-08-12 |
mouse |
| Zuzanna Michalak, Takanori Sano, Tobias Engel, Suzanne F C Miller-Delaney, Mireille Lerner-Natoli, David C Henshal. Spatio-temporally restricted blood-brain barrier disruption after intra-amygdala kainic acid-induced status epilepticus in mice. Epilepsy research. vol 103. issue 2-3. 2013-10-22. PMID:23182415. |
increased igg and albumin were detected in damaged and non-damaged ipsilateral hippocampal subfields, mainly 4-24h after status epilepticus, although increased serum protein extravasation was also found in the ca3 subfield in epileptic mice. |
2013-10-22 |
2023-08-12 |
mouse |
| Yu-Wen Hung, Ming-Tsong Lai, Yi-Jhan Tseng, Chien-Chen Chou, Yung-Yang Li. Monocyte chemoattractant protein-1 affects migration of hippocampal neural progenitors following status epilepticus in rats. Journal of neuroinflammation. vol 10. 2013-10-22. PMID:23339567. |
monocyte chemoattractant protein-1 affects migration of hippocampal neural progenitors following status epilepticus in rats. |
2013-10-22 |
2023-08-12 |
rat |
| Yu-Wen Hung, Ming-Tsong Lai, Yi-Jhan Tseng, Chien-Chen Chou, Yung-Yang Li. Monocyte chemoattractant protein-1 affects migration of hippocampal neural progenitors following status epilepticus in rats. Journal of neuroinflammation. vol 10. 2013-10-22. PMID:23339567. |
in the present study, we investigated the involvement of monocyte chemoattractant protein-1 (mcp-1) in aberrant migration of hippocampal progenitors in rats after the insult of status epilepticus (se). |
2013-10-22 |
2023-08-12 |
rat |
| Yasser A Khadrawy, Heba S Aboulezz, Nawal A Ahmed, Haitham S Mohamme. The anticonvulant effect of cooling in comparison to α-lipoic acid: a neurochemical study. Neurochemical research. vol 38. issue 5. 2013-10-22. PMID:23389664. |
the aim of the present study is to evaluate the anticonvulsant effect of brain cooling on the oxidative stress and changes in na(+), k(+)-atpase and acetylcholinesterase (ache) activities during status epilepticus induced by pilocarpine in the hippocampus of adult male rat in comparison with α-lipoic acid. |
2013-10-22 |
2023-08-12 |
rat |
| Young Se Kwon, Eduardo Pineda, Stéphane Auvin, Don Shin, Andrey Mazarati, Raman Sanka. Neuroprotective and antiepileptogenic effects of combination of anti-inflammatory drugs in the immature brain. Journal of neuroinflammation. vol 10. 2013-10-22. PMID:23442201. |
in this study, developing rat pups were subjected to lithium-pilocarpine status epilepticus (se) at 2 and 3 weeks of age to study the effect of anti-inflammatory drugs (aid) on se-induced hippocampal injury and the development of spontaneous seizures. |
2013-10-22 |
2023-08-12 |
rat |
| Premysl Jiruska, Anan B Y Shtaya, David M S Bodansky, Wei-Chih Chang, William P Gray, John G R Jeffery. Dentate gyrus progenitor cell proliferation after the onset of spontaneous seizures in the tetanus toxin model of temporal lobe epilepsy. Neurobiology of disease. vol 54. 2013-10-21. PMID:23439313. |
we conclude that repeated spontaneous brief temporal lobe seizures are sufficient to promote increased hippocampal neurogenesis in the absence of status epilepticus. |
2013-10-21 |
2023-08-12 |
rat |
| Markus Marx, Carola A Haas, Ute Häussle. Differential vulnerability of interneurons in the epileptic hippocampus. Frontiers in cellular neuroscience. vol 7. 2013-10-07. PMID:24098270. |
we used the intrahippocampal kainate (ka) mouse model for tle in which a focal, unilateral ka injection induces status epilepticus (se) followed by development of granule cell dispersion (gcd) and hippocampal sclerosis surrounding the injection site but not in the intermediate and temporal hippocampus. |
2013-10-07 |
2023-08-12 |
mouse |
| Gabriele Baj, Domenico Del Turco, Jessica Schlaudraff, Lucio Torelli, Thomas Deller, Enrico Tongiorg. Regulation of the spatial code for BDNF mRNA isoforms in the rat hippocampus following pilocarpine-treatment: a systematic analysis using laser microdissection and quantitative real-time PCR. Hippocampus. vol 23. issue 5. 2013-09-30. PMID:23436435. |
in this study, using laser microdissection of hippocampal laminae and reverse transcription-quantitative real-time pcr (rt-qpcr), we analyzed all known bdnf mrna variants at resting conditions or following 3 h pilocarpine-induced status epilepticus. |
2013-09-30 |
2023-08-12 |
rat |
| Gumei Liu, Bin Gu, Xiao-Ping He, Rasesh B Joshi, Harold D Wackerle, Ramona Marie Rodriguiz, William C Wetsel, James O McNamar. Transient inhibition of TrkB kinase after status epilepticus prevents development of temporal lobe epilepsy. Neuron. vol 79. issue 1. 2013-09-26. PMID:23790754. |
we investigated a mouse model in which a brief episode of status epilepticus results in chronic recurrent seizures, anxiety-like behavior, and destruction of hippocampal neurons. |
2013-09-26 |
2023-08-12 |
mouse |
| Gumei Liu, Bin Gu, Xiao-Ping He, Rasesh B Joshi, Harold D Wackerle, Ramona Marie Rodriguiz, William C Wetsel, James O McNamar. Transient inhibition of TrkB kinase after status epilepticus prevents development of temporal lobe epilepsy. Neuron. vol 79. issue 1. 2013-09-26. PMID:23790754. |
we demonstrate that inhibition of trkb commencing after status epilepticus and continued for 2 weeks prevents recurrent seizures, ameliorates anxiety-like behavior, and limits loss of hippocampal neurons when tested weeks to months later. |
2013-09-26 |
2023-08-12 |
mouse |
| Heng Yang, Ren Guo, Jiongxing Wu, Yufeng Peng, Dujie Xie, Wen Zheng, Xian Huang, Ding Liu, Wei Liu, Lihua Huang, Zhi Son. The antiepileptic effect of the glycolytic inhibitor 2-deoxy-D-glucose is mediated by upregulation of K(ATP) channel subunits Kir6.1 and Kir6.2. Neurochemical research. vol 38. issue 4. 2013-09-12. PMID:23475455. |
to explore whether 2-dg exerts an antiepileptic effect through upregulation of the k(atp) channel subunits kir6.1 and kir6.2, the expression of these subunits in hippocampus of five groups of mice with pilocarpine-induced status epilepticus (se) was evaluated. |
2013-09-12 |
2023-08-12 |
mouse |
| Robert S Sloviter, Argyle V Bumangla. Defining "epileptogenesis" and identifying "antiepileptogenic targets" in animal models of acquired temporal lobe epilepsy is not as simple as it might seem. Neuropharmacology. vol 69. 2013-09-06. PMID:22342985. |
this indicates that hippocampal injury caused by convulsive status epilepticus is immediately epileptogenic and that hippocampal epileptogenesis requires no delayed secondary mechanism. |
2013-09-06 |
2023-08-12 |
rat |
| Gary P Brennan, Eva M Jimenez-Mateos, Ross C McKiernan, Tobias Engel, Guri Tzivion, David C Henshal. Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo. PloS one. vol 8. issue 1. 2013-09-06. PMID:23359526. |
transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo. |
2013-09-06 |
2023-08-12 |
mouse |
| Thomas Licko, Natalie Seeger, Christina Zellinger, Vera Russmann, Alain Matagne, Heidrun Potschk. Lacosamide treatment following status epilepticus attenuates neuronal cell loss and alterations in hippocampal neurogenesis in a rat electrical status epilepticus model. Epilepsia. vol 54. issue 7. 2013-09-06. PMID:23614482. |
lacosamide treatment following status epilepticus attenuates neuronal cell loss and alterations in hippocampal neurogenesis in a rat electrical status epilepticus model. |
2013-09-06 |
2023-08-12 |
rat |
| Yan Deng, Minghuan Wang, Wei Wang, Chao Ma, Nongyue H. Comparison and effects of acute lamotrigine treatment on extracellular excitatory amino acids in the hippocampus of PTZ-kindled epileptic and PTZ-induced status epilepticus rats. Neurochemical research. vol 38. issue 3. 2013-08-15. PMID:23229790. |
comparison and effects of acute lamotrigine treatment on extracellular excitatory amino acids in the hippocampus of ptz-kindled epileptic and ptz-induced status epilepticus rats. |
2013-08-15 |
2023-08-12 |
rat |