| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F M Leweke, A Giuffrida, U Wurster, H M Emrich, D Piomell. Elevated endogenous cannabinoids in schizophrenia. Neuroreport. vol 10. issue 8. 1999-11-15. PMID:10501554. |
evidence suggests that cannabinoid receptors, the pharmacologcial target of cannabis-derived drugs, and their accompanying system of endogenous activators may be dysfunctional in schizophrenia. |
1999-11-15 |
2023-08-12 |
Not clear |
| F M Leweke, A Giuffrida, U Wurster, H M Emrich, D Piomell. Elevated endogenous cannabinoids in schizophrenia. Neuroreport. vol 10. issue 8. 1999-11-15. PMID:10501554. |
endogenous cannabinoids were purified from cerebrospinal fluid of 10 patients with schizophrenia and 11 non-schizophrenic controls by high-performance liquid chromatography, and quantified by isotope dilution gas-chromatography/mass-spectrometry. |
1999-11-15 |
2023-08-12 |
Not clear |
| F M Leweke, A Giuffrida, U Wurster, H M Emrich, D Piomell. Elevated endogenous cannabinoids in schizophrenia. Neuroreport. vol 10. issue 8. 1999-11-15. PMID:10501554. |
elevated anandamide and palmitylethanolamide levels in cerebrospinal fluid of schizophrenic patients may reflect an imbalance in endogenous cannabinoid signaling, which may contribute to the pathogenesis of schizophrenia. |
1999-11-15 |
2023-08-12 |
Not clear |
| b' M Poncelet, M C Barnouin, J C Breli\\xc3\\xa8re, G Le Fur, P Soubri\\xc3\\xa. Blockade of cannabinoid (CB1) receptors by 141716 selectively antagonizes drug-induced reinstatement of exploratory behaviour in gerbils. Psychopharmacology. vol 144. issue 2. 1999-08-17. PMID:10394995.' |
a cannabinoid hypothesis of schizophrenia has been proposed according to which cognitive dysfunction could be associated with dysregulation of an endogenous cannabinoid system. |
1999-08-17 |
2023-08-12 |
Not clear |
| M A Gorriti, F Rodríguez de Fonseca, M Navarro, T Palom. Chronic (-)-delta9-tetrahydrocannabinol treatment induces sensitization to the psychomotor effects of amphetamine in rats. European journal of pharmacology. vol 365. issue 2-3. 1999-04-29. PMID:9988095. |
clinical and basic research studies have linked cannabinoid consumption to the onset of psychosis, specially schizophrenia. |
1999-04-29 |
2023-08-12 |
rat |
| H M Emrich, F M Leweke, U Schneide. Towards a cannabinoid hypothesis of schizophrenia: cognitive impairments due to dysregulation of the endogenous cannabinoid system. Pharmacology, biochemistry, and behavior. vol 56. issue 4. 1997-07-07. PMID:9130308. |
towards a cannabinoid hypothesis of schizophrenia: cognitive impairments due to dysregulation of the endogenous cannabinoid system. |
1997-07-07 |
2023-08-12 |
human |