| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T A Bayer, M Schramm, N Feldmann, M B Knable, P Falka. Antidepressant drug exposure is associated with mRNA levels of tyrosine receptor kinase B in major depressive disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 24. issue 6. 2001-02-08. PMID:11041531. |
using a quantitative rt-pcr approach trk b mrna levels were determined in brain material from cerebellum, temporal cortex, and frontal cortex of control specimen and patients with major depressive disorder, schizophrenia and bipolar disorder (15 subjects each). |
2001-02-08 |
2023-08-12 |
human |
| L L Sears, N C Andreasen, D S O'Lear. Cerebellar functional abnormalities in schizophrenia are suggested by classical eyeblink conditioning. Biological psychiatry. vol 48. issue 3. 2000-09-21. PMID:10924663. |
cerebellar functional abnormalities in schizophrenia are suggested by classical eyeblink conditioning. |
2000-09-21 |
2023-08-12 |
Not clear |
| L L Sears, N C Andreasen, D S O'Lear. Cerebellar functional abnormalities in schizophrenia are suggested by classical eyeblink conditioning. Biological psychiatry. vol 48. issue 3. 2000-09-21. PMID:10924663. |
to further evaluate the cerebellar contribution to this disrupted circuitry, medication-free patients with schizophrenia completed classical eyeblink conditioning, a cerebellar-mediated learning task. |
2000-09-21 |
2023-08-12 |
Not clear |
| E V Sullivan, A Deshmukh, J E Desmond, D H Mathalon, M J Rosenbloom, K O Lim, A Pfefferbau. Contribution of alcohol abuse to cerebellar volume deficits in men with schizophrenia. Archives of general psychiatry. vol 57. issue 9. 2000-09-21. PMID:10986553. |
contribution of alcohol abuse to cerebellar volume deficits in men with schizophrenia. |
2000-09-21 |
2023-08-12 |
Not clear |
| E V Sullivan, A Deshmukh, J E Desmond, D H Mathalon, M J Rosenbloom, K O Lim, A Pfefferbau. Contribution of alcohol abuse to cerebellar volume deficits in men with schizophrenia. Archives of general psychiatry. vol 57. issue 9. 2000-09-21. PMID:10986553. |
it is controversial whether cerebellar tissue volume deficits occur in schizophrenia and, if so, what regions and tissue types are affected. |
2000-09-21 |
2023-08-12 |
Not clear |
| E V Sullivan, A Deshmukh, J E Desmond, D H Mathalon, M J Rosenbloom, K O Lim, A Pfefferbau. Contribution of alcohol abuse to cerebellar volume deficits in men with schizophrenia. Archives of general psychiatry. vol 57. issue 9. 2000-09-21. PMID:10986553. |
complicating such investigations is the high incidence of alcoholism comorbidity in patients with schizophrenia that itself can contribute to cerebellar abnormalities. |
2000-09-21 |
2023-08-12 |
Not clear |
| A G Alia. Schizotypy and leadership: a contrasting model for deficit symptoms, and a possible therapeutic role for sex hormones. Medical hypotheses. vol 54. issue 4. 2000-07-10. PMID:10859637. |
andreasen et al postulate that a disruption in the circuitry among nodes located in the prefrontal regions, the thalamic nuclei, and the cerebellum produces 'cognitive dysmetria', meaning difficulty in prioritizing, coordinating, and responding to information, and that it can account for the broad diversity of symptoms of schizophrenia. |
2000-07-10 |
2023-08-12 |
Not clear |
| T Supprian, G Ulmar, M Bauer, M Schüler, K Püschel, P Retz-Junginger, H P Schmitt, H Heinse. Cerebellar vermis area in schizophrenic patients - a post-mortem study. Schizophrenia research. vol 42. issue 1. 2000-05-10. PMID:10706982. |
neuroimaging studies of cerebellar atrophy in schizophrenia have yielded contradictory results. |
2000-05-10 |
2023-08-12 |
human |
| D S Melchitzky, D A Lewi. Tyrosine hydroxylase- and dopamine transporter-immunoreactive axons in the primate cerebellum. Evidence for a lobular- and laminar-specific dopamine innervation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 22. issue 5. 2000-05-09. PMID:10731621. |
the cerebellum seems to play a critical role in many motor and cognitive functions, including those that are disturbed in schizophrenia. |
2000-05-09 |
2023-08-12 |
monkey |
| J J Kim, S Mohamed, N C Andreasen, D S O'Leary, G L Watkins, L L Boles Ponto, R D Hichw. Regional neural dysfunctions in chronic schizophrenia studied with positron emission tomography. The American journal of psychiatry. vol 157. issue 4. 2000-04-20. PMID:10739412. |
the authors previously compared healthy volunteers with neuroleptic-naive patients experiencing their first episode of schizophrenia and reported that abnormalities in blood flow, including lower flow in prefrontal regions and higher flow in the thalamus and cerebellum, are present at the early stage of schizophrenic illness. |
2000-04-20 |
2023-08-12 |
human |
| D C German, K F Manaye, D Wu, L B Hersh, R M Zwei. Mesopontine cholinergic and non-cholinergic neurons in schizophrenia. Neuroscience. vol 94. issue 1. 2000-01-14. PMID:10613494. |
mesopontine cholinergic neurons influence midbrain dopaminergic neurons, and thalamic and cerebellar structures which have been implicated in the neuroanatomy of schizophrenia. |
2000-01-14 |
2023-08-12 |
Not clear |
| S V Kyosseva, A D Elbein, W S Griffin, R E Mrak, M Lyon, C N Karso. Mitogen-activated protein kinases in schizophrenia. Biological psychiatry. vol 46. issue 5. 1999-12-29. PMID:10472421. |
our focus was on the cerebellar vermis because of evidence suggesting that schizophrenia is associated with abnormalities of structure, function, and signal transduction in this brain region. |
1999-12-29 |
2023-08-12 |
human |
| P C Nopoulos, J W Ceilley, E A Gailis, N C Andrease. An MRI study of cerebellar vermis morphology in patients with schizophrenia: evidence in support of the cognitive dysmetria concept. Biological psychiatry. vol 46. issue 5. 1999-12-29. PMID:10472423. |
an mri study of cerebellar vermis morphology in patients with schizophrenia: evidence in support of the cognitive dysmetria concept. |
1999-12-29 |
2023-08-12 |
Not clear |
| P C Nopoulos, J W Ceilley, E A Gailis, N C Andrease. An MRI study of cerebellar vermis morphology in patients with schizophrenia: evidence in support of the cognitive dysmetria concept. Biological psychiatry. vol 46. issue 5. 1999-12-29. PMID:10472423. |
cumulative evidence suggests the cerebellum is involved in cognition and may be important in the pathoetiology of schizophrenia. |
1999-12-29 |
2023-08-12 |
Not clear |
| P C Nopoulos, J W Ceilley, E A Gailis, N C Andrease. An MRI study of cerebellar vermis morphology in patients with schizophrenia: evidence in support of the cognitive dysmetria concept. Biological psychiatry. vol 46. issue 5. 1999-12-29. PMID:10472423. |
to explore the role of the cerebellum in cognitive dysfunction and schizophrenia, this study was designed to evaluate the morphology of the cerebellar vermis, its relationship to other cortical areas, and to cognitive function in patients with schizophrenia. |
1999-12-29 |
2023-08-12 |
Not clear |
| H Tashiro, S O Suzuki, T Hitotsumatsu, T Iwak. An autopsy case of spinocerebellar ataxia type 6 with mental symptoms of schizophrenia and dementia. Clinical neuropathology. vol 18. issue 4. 1999-09-09. PMID:10442462. |
a 39-year-old man who showed slowly progressive mental disorders and gait ataxia was clinically diagnosed to have cortical cerebellar atrophy (cca) and schizophrenia. |
1999-09-09 |
2023-08-12 |
Not clear |
| J J Levitt, R W McCarley, P G Nestor, C Petrescu, R Donnino, Y Hirayasu, R Kikinis, F A Jolesz, M E Shento. Quantitative volumetric MRI study of the cerebellum and vermis in schizophrenia: clinical and cognitive correlates. The American journal of psychiatry. vol 156. issue 7. 1999-07-30. PMID:10401463. |
quantitative volumetric mri study of the cerebellum and vermis in schizophrenia: clinical and cognitive correlates. |
1999-07-30 |
2023-08-12 |
Not clear |
| J J Levitt, R W McCarley, P G Nestor, C Petrescu, R Donnino, Y Hirayasu, R Kikinis, F A Jolesz, M E Shento. Quantitative volumetric MRI study of the cerebellum and vermis in schizophrenia: clinical and cognitive correlates. The American journal of psychiatry. vol 156. issue 7. 1999-07-30. PMID:10401463. |
recent evidence suggests that the cerebellum may play a role in higher cognitive functions and, therefore, may play an important role in schizophrenia. |
1999-07-30 |
2023-08-12 |
Not clear |
| C E Helmkamp, L B Bigelow, J D Paltán-Ortiz, E F Torrey, J E Kleinman, M M Herma. Evaluation of superior vermal Purkinje cell placement in mental illness. Biological psychiatry. vol 45. issue 10. 1999-07-02. PMID:10349043. |
a number of neuroimaging and neuropathological studies have reported abnormalities in the cerebellar vermis in schizophrenia and bipolar disorder. |
1999-07-02 |
2023-08-12 |
Not clear |
| R T Loeber, A R Sherwood, P F Renshaw, B M Cohen, D A Yurgelun-Tod. Differences in cerebellar blood volume in schizophrenia and bipolar disorder. Schizophrenia research. vol 37. issue 1. 1999-06-10. PMID:10227110. |
differences in cerebellar blood volume in schizophrenia and bipolar disorder. |
1999-06-10 |
2023-08-12 |
human |