All Relations between Schizophrenia and pde10a
| Publication | Sentence | Publish Date | Extraction Date | Species |
|---|---|---|---|---|
| Frank S Menniti, Thomas A Chappie, John M Humphrey, Christopher J Schmid. Phosphodiesterase 10A inhibitors: a novel approach to the treatment of the symptoms of schizophrenia. Current opinion in investigational drugs (London, England : 2000). vol 8. issue 1. 2007-05-08. PMID:17263185. | in addition, by enhancing corticostriatal signaling, pde10a inhibitors have the potential to improve some of the cognitive symptoms of schizophrenia. | 2007-05-08 | 2023-08-12 | Not clear |
| Joshua S Rodefer, Emily R Murphy, Mark G Baxte. PDE10A inhibition reverses subchronic PCP-induced deficits in attentional set-shifting in rats. The European journal of neuroscience. vol 21. issue 4. 2005-05-16. PMID:15787711. | these data suggest that subchronic pcp administration may model effectively some of the cognitive deficits that are observed in schizophrenia, and that pde10a inhibition may be an effective therapeutic route to improve executive function deficits associated with schizophrenia. | 2005-05-16 | 2023-08-12 | rat |