| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christoph U Correll, Marco Solmi, Giovanni Croatto, Lynne Kolton Schneider, S Christy Rohani-Montez, Leanne Fairley, Nathalie Smith, István Bitter, Philip Gorwood, Heidi Taipale, Jari Tiihone. Mortality in people with schizophrenia: a systematic review and meta-analysis of relative risk and aggravating or attenuating factors. World psychiatry : official journal of the World Psychiatric Association (WPA). vol 21. issue 2. 2022-05-07. PMID:35524619. |
across 135 studies spanning from 1957 to 2021 (schizophrenia: n=4,536,447; general population controls: n=1,115,600,059; other psychiatric illness controls: n=3,827,955), all-cause mortality was increased in people with schizophrenia versus any non-schizophrenia control group (rr=2.52, 95% ci: 2.38-2.68, n=79), with the largest risk in first-episode (rr=7.43, 95% ci: 4.02-13.75, n=2) and incident (i.e., earlier-phase) schizophrenia (rr=3.52, 95% ci: 3.09-4.00, n=7) versus the general population. |
2022-05-07 |
2023-08-13 |
Not clear |
| Aniqa B Alam, Pamela L Lutsey, Lin Y Chen, Richard F MacLehose, Iris Y Shao, Alvaro Alons. Risk Factors for Dementia in Patients With Atrial Fibrillation. The American journal of cardiology. 2022-04-27. PMID:35473779. |
the strongest predictors of dementia were frailty (hazard ratio [hr] 1.43, 95% confidence interval [ci] 1.40 to 1.45, per 1-sd increase in the score), cognitive impairment (hr 1.50, 95% ci 1.36 to 1.65), mood disorders (hr 1.49, 95% ci 1.32 to 1.70), schizophrenia (hr 1.86, 95% ci 1.75 to 1.98), and substance abuse (hr 1.58, 95% ci 1.39 to 1.80). |
2022-04-27 |
2023-08-13 |
Not clear |
| Ying-Jay Liou, Shih-Jen Tsai, Ya-Mei Bai, Tzeng-Ji Chen, Mu-Hong Che. Dementia risk in middle-aged patients with schizophrenia, bipolar disorder, and major depressive disorder: a cohort study of 84,824 subjects. European archives of psychiatry and clinical neuroscience. 2022-04-26. PMID:35469078. |
alzheimer disease was more likely in patients with bipolar disorder (hazard ratio [hr]: 10.37, 95% confidence interval [ci]: 6.93-15.52) and major depression (hr: 8.92, 95% ci: 5.93-13.41) than in those with schizophrenia (hr: 4.50, 95% ci: 2.84-7.13) and in controls. |
2022-04-26 |
2023-08-13 |
human |
| Ying-Jay Liou, Shih-Jen Tsai, Ya-Mei Bai, Tzeng-Ji Chen, Mu-Hong Che. Dementia risk in middle-aged patients with schizophrenia, bipolar disorder, and major depressive disorder: a cohort study of 84,824 subjects. European archives of psychiatry and clinical neuroscience. 2022-04-26. PMID:35469078. |
the likelihood of developing vascular dementia during the follow-up period was greater in patients with schizophrenia (hr: 4.55, 95% ci: 3.14-6.59) and bipolar disorder (hr: 4.45, 95% ci: 3.13-6.31) than in those with major depression (hr: 3.18, 95% ci: 2.21-4.58) and in controls. |
2022-04-26 |
2023-08-13 |
human |
| Amal Adnan Ashour, Mohammed Khalil Fahmi, Roshan Noor Mohamed, Sakeenabi Basha, Nada Binmadi, Enas Tawfik Enan, Alaa Basalim, Abeer Al Qahatan. Association between gastric reflux, obesity and erosive tooth wear among psychiatric patients. Medicine. vol 101. issue 7. 2022-04-01. PMID:35363217. |
regression analysis showed a strong association between erosive tooth wear and chronic vomiting or bulimia (adjusted odds ratio = 2.11; 95% confidence interval [ci] = 1.98-5.07, p < .001), gastric reflux (adjusted odds ratio = 2.13; 95% ci = 1.34-6.23, p < .001), consumption of soft drinks (adjusted odds ratio = 2.14; 95% ci = 1.03-6.08, p < .001), and schizophrenia and delusional disorders (adjusted odds ratio = 2.07; 95% ci = 1.98-5.08, p < .001).this study demonstrates a significant association between erosive tooth wear prevalence and chronic vomiting or bulimia, consumption of soft drinks, and gastric reflux among resident patients at psychiatric hospital. |
2022-04-01 |
2023-08-13 |
Not clear |
| Claire A Wilson, James Newham, Judith Rankin, Khalida Ismail, Emily Simonoff, Rebecca M Reynolds, Nkasi Stoll, Louise M Howar. Systematic review and meta-analysis of risk of gestational diabetes in women with preconception mental disorders. Journal of psychiatric research. vol 149. 2022-03-23. PMID:35320739. |
there was evidence for an increased risk of gdm in women with schizophrenia (pooled or 2.44; 95% ci 1.17,5.1; 5 studies) and a reduced risk of gdm in women with anorexia nervosa (pooled or 0.63; 95% ci 0.49,0.80; 5 studies). |
2022-03-23 |
2023-08-13 |
Not clear |
| Suhailah Ali, Damian Santomauro, Alize J Ferrari, Fiona Charlso. Excess mortality in severe mental disorders: A systematic review and meta-regression. Journal of psychiatric research. vol 149. 2022-03-08. PMID:35259666. |
the adjusted rr for all-cause mortality in schizophrenia was 2.89 (95% ci 2.50 to 3.34) and 2.51 (95%ci 2.10 to 3.00) for bipolar disorder. |
2022-03-08 |
2023-08-13 |
Not clear |
| Marie Reeberg Sass, Tobias Søgaard Juul, Robert Skov, Kasper Iversen, Lene Holm Harritshøj, Erik Sørensen, Sisse Rye Ostrowski, Ove Andersen, Claus Thorn Ekstrøm, Henrik Ullum, Jimmi Nielsen, Ida Hageman, Anders Fink-Jense. SARS-CoV-2 seroprevalence among patients with severe mental illness: A cross-sectional study. PloS one. vol 17. issue 3. 2022-03-01. PMID:35231037. |
no significant differences in seroprevalences between schizophrenia and bipolar disease were found (rr = 1.12; 95% ci 0.67-1.87; p = .667). |
2022-03-01 |
2023-08-13 |
human |
| Sara Guillen-Aguinaga, Antonio Brugos-Larumbe, Laura Guillen-Aguinaga, Felipe Ortuño, Francisco Guillen-Grima, Luis Forga, Ines Aguinaga-Ontos. Schizophrenia and Hospital Admissions for Cardiovascular Events in a Large Population: The APNA Study. Journal of cardiovascular development and disease. vol 9. issue 1. 2022-01-20. PMID:35050235. |
in non-adherent to antipsychotic treatment schizophrenia patients, the hr was 2.232 (95% ci 1.267-3.933). |
2022-01-20 |
2023-08-13 |
Not clear |
| Chunyu Li, Tianmi Yang, Ruwei Ou, Huifang Shan. Overlapping Genetic Architecture Between Schizophrenia and Neurodegenerative Disorders. Frontiers in cell and developmental biology. vol 9. 2022-01-10. PMID:35004692. |
we identified positive and significant correlation between schizophrenia and als at genetic (correlation 0.22; 95% ci: 0.16-0.28; |
2022-01-10 |
2023-08-13 |
Not clear |
| Augusto Castagnini, Leslie Foldager, Ernesto Caffo, German E Berrio. The predictive validity and outcome of ICD-10 and DSM-5 short-lived psychotic disorders: a review and meta-analysis. European archives of psychiatry and clinical neuroscience. 2022-01-06. PMID:34988647. |
meta-analysis of 25 studies (13,507 cases) revealed that 55% (95% ci 49-62) do not change diagnosis, 25% (95% ci 20-31) converted into schizophrenia and related disorders, and 12% (95% ci 7-16) into affective disorders on average over 6.3 years. |
2022-01-06 |
2023-08-13 |
Not clear |
| Anthony W Zoghbi, Ryan S Dhindsa, Terry E Goldberg, Aydan Mehralizade, Joshua E Motelow, Xinchen Wang, Anna Alkelai, Matthew B Harms, Jeffrey A Lieberman, Sander Markx, David B Goldstei. High-impact rare genetic variants in severe schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 51. 2021-12-14. PMID:34903660. |
individuals with severe, extremely treatment-resistant schizophrenia had a high burden of rare loss-of-function (odds ratio, 1.91; 95% ci, 1.39 to 2.63; |
2021-12-14 |
2023-08-13 |
Not clear |
| Dariusz Juchnowicz, Michał Dzikowski, Joanna Rog, Napoleon Waszkiewicz, Anna Zalewska, Mateusz Maciejczyk, Hanna Karakuła-Juchnowic. Oxidative Stress Biomarkers as a Predictor of Stage Illness and Clinical Course of Schizophrenia. Frontiers in psychiatry. vol 12. 2021-12-07. PMID:34867519. |
in the regression model adjusted for cofounders, catalase: or = 0.81 (95%ci: 0.74-0.88); glutathione peroxidase: or = 1.06 (95%ci: 1.02-1.10); total antioxidant capacity: or = 0.85 (95%ci: 0.75-0.98); oxidative stress index: or = 1.25 (95%ci: 1.03-1.52); ferric reducing ability of plasma: or = 0.79 (95%ci: 0.69-0.89); advanced glycation end products: or = 1.03 (95%ci: 1.01-1.04); and advanced oxidation protein products (aopp): or = 1.05 (95%ci: 1.03-1.07) turned out to be significant predictors of schizophrenia. |
2021-12-07 |
2023-08-13 |
cat |
| Emanuele F Osimo, Mark Sweeney, Antonio de Marvao, Alaine Berry, Ben Statton, Benjamin I Perry, Toby Pillinger, Thomas Whitehurst, Stuart A Cook, Declan P O'Regan, E Louise Thomas, Oliver D Howe. Adipose tissue dysfunction, inflammation, and insulin resistance: alternative pathways to cardiac remodelling in schizophrenia. A multimodal, case-control study. Translational psychiatry. vol 11. issue 1. 2021-12-07. PMID:34873143. |
participants with schizophrenia showed increases in cardiac concentricity (d = 0.71, 95% ci: 0.12, 1.30; p = 0.01), indicative of ccr, but showed no differences in overall content or regional distribution of adipose tissue compared to hcs. |
2021-12-07 |
2023-08-13 |
human |
| Emanuele F Osimo, Mark Sweeney, Antonio de Marvao, Alaine Berry, Ben Statton, Benjamin I Perry, Toby Pillinger, Thomas Whitehurst, Stuart A Cook, Declan P O'Regan, E Louise Thomas, Oliver D Howe. Adipose tissue dysfunction, inflammation, and insulin resistance: alternative pathways to cardiac remodelling in schizophrenia. A multimodal, case-control study. Translational psychiatry. vol 11. issue 1. 2021-12-07. PMID:34873143. |
despite the cardiac changes, participants with schizophrenia did not demonstrate activation of the hypertensive ccr pathway; however, they showed evidence of adipose dysfunction: adiponectin was reduced (d = -0.69, 95% ci: -1.28, -0.10; p = 0.02), with evidence of activation of downstream pathways, including hypertriglyceridemia, elevated c-reactive protein, fasting glucose, and alkaline phosphatase. |
2021-12-07 |
2023-08-13 |
human |
| Vincenzo Oliva, Giuseppe Fanelli, Siegfried Kasper, Joseph Zohar, Daniel Souery, Stuart Montgomery, Diego Albani, Gianluigi Forloni, Panagiotis Ferentinos, Dan Rujescu, Julien Mendlewicz, Martien J Kas, Diana De Ronchi, Chiara Fabbri, Alessandro Serrett. Social withdrawal as a trans-diagnostic predictor of short-term remission: a meta-analysis of five clinical cohorts. International clinical psychopharmacology. 2021-12-02. PMID:34855649. |
the meta-analysis showed that higher baseline levels of social withdrawal were associated with a decreased likelihood of short-term remission (oradj = 0.67, 95% ci, 0.58-0.79, p = 5.28 × 10-7), with the strongest effect in patients with schizophrenia. |
2021-12-02 |
2023-08-13 |
Not clear |
| Joe Kwun Nam Chan, Corine Sau Man Wong, Philip Chi Fai Or, Eric Yu Hai Chen, Wing Chung Chan. Diabetes complication burden and patterns and risk of mortality in people with schizophrenia and diabetes: A population-based cohort study with 16-year follow-up. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 53. 2021-11-30. PMID:34481187. |
schizophrenia group had comparable macrovascular (adjusted or 0.99 [95% ci 0.92-1.06]) and lower microvascular (0.79 [0.73-0.86]) complication rates relative to comparison group. |
2021-11-30 |
2023-08-13 |
Not clear |
| Nicholas Chak Lam Yung, Corine Sau Man Wong, Joe Kwun Nam Chan, Eric Yu Hai Chen, Wing Chung Chan. Excess Mortality and Life-Years Lost in People With Schizophrenia and Other Non-affective Psychoses: An 11-Year Population-Based Cohort Study. Schizophrenia bulletin. vol 47. issue 2. 2021-11-22. PMID:33009566. |
results showed that schizophrenia and onap patients had higher all-cause (schizophrenia: smr: 2.49 [95% ci: 2.43-2.55]; onap: 2.00 [1.92-2.09]), natural-cause (1.80 [1.74-1.85]; 1.47 [1.40-1.54]), and unnatural-cause (6.97 [6.47-7.49]; 8.53 [7.61-9.52]) mortality rates than general population. |
2021-11-22 |
2023-08-13 |
Not clear |
| Xiao-Ni Sun, Jian-Bo Zhou, Na L. Poor Oral Health in Patients with Schizophrenia: a Meta-Analysis of Case-Control Studies. The Psychiatric quarterly. vol 92. issue 1. 2021-11-09. PMID:32483766. |
patients with schizophrenia had significantly higher scores of decayed, missing and filled teeth (smd = 0.83, 95%ci: 0.57, 1.09, p < 0.001; i |
2021-11-09 |
2023-08-13 |
Not clear |
| Kristine Engemann, Carsten Bøcker Pedersen, Esben Agerbo, Lars Arge, Anders Dupont Børglum, Christian Erikstrup, Ole Hertel, David Michael Hougaard, John J McGrath, Ole Mors, Preben Bo Mortensen, Merete Nordentoft, Clive Eric Sabel, Torben Sigsgaard, Constantinos Tsirogiannis, Bjarni Jóhann Vilhjálmsson, Thomas Werge, Jens-Christian Svenning, Henriette Thisted Horsda. Association Between Childhood Green Space, Genetic Liability, and the Incidence of Schizophrenia. Schizophrenia bulletin. vol 46. issue 6. 2021-10-25. PMID:32415773. |
the adjusted hrs show that growing up surrounded by the highest compared to the lowest decile of ndvi was associated with a 0.52-fold (95% confidence interval [ci]: 0.40 to 0.66) lower schizophrenia risk, and children with the highest polygenic risk score had a 1.24-fold (95% ci: 1.18 to 1.30) higher schizophrenia risk. |
2021-10-25 |
2023-08-13 |
Not clear |