| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thanh P Le, Michael F Green, Junghee Lee, Peter E Clayson, Amy M Jimenez, Eric A Reavis, Jonathan K Wynn, William P Hora. Aberrant reward processing to positive versus negative outcomes across psychotic disorders. Journal of psychiatric research. vol 156. 2022-10-06. PMID:36201975. |
the current findings suggest reward processing disturbances, particularly decreased sensitivity to positive outcomes, extend beyond schizophrenia to a broader spectrum of psychotic disorders and relate to important clinical outcomes. |
2022-10-06 |
2023-08-14 |
Not clear |
| Mariia Kaliuzhna, Matthias Kirschner, Philippe N Tobler, Stefan Kaise. Comparing adaptive coding of reward in bipolar I disorder and schizophrenia. Human brain mapping. 2022-09-16. PMID:36111883. |
comparing adaptive coding of reward in bipolar i disorder and schizophrenia. |
2022-09-16 |
2023-08-14 |
human |
| Mariia Kaliuzhna, Matthias Kirschner, Philippe N Tobler, Stefan Kaise. Comparing adaptive coding of reward in bipolar I disorder and schizophrenia. Human brain mapping. 2022-09-16. PMID:36111883. |
deficits in neural processing of reward have been described in both bipolar disorder (bd) and schizophrenia (sz), but it remains unclear to what extent these deficits are caused by similar mechanisms. |
2022-09-16 |
2023-08-14 |
human |
| Stephen J Kaar, Ilinca Angelescu, Matthew M Nour, Tiago Reis Marques, Alice Sharman, Anil Sajjala, John Hutchison, Philip McGuire, Charles Large, Oliver D Howe. The effects of AUT00206, a novel Kv3.1/3.2 potassium channel modulator, on task-based reward system activation: a test of mechanism in schizophrenia. Psychopharmacology. 2022-09-12. PMID:36094619. |
the effects of aut00206, a novel kv3.1/3.2 potassium channel modulator, on task-based reward system activation: a test of mechanism in schizophrenia. |
2022-09-12 |
2023-08-14 |
human |
| Stephen J Kaar, Ilinca Angelescu, Matthew M Nour, Tiago Reis Marques, Alice Sharman, Anil Sajjala, John Hutchison, Philip McGuire, Charles Large, Oliver D Howe. The effects of AUT00206, a novel Kv3.1/3.2 potassium channel modulator, on task-based reward system activation: a test of mechanism in schizophrenia. Psychopharmacology. 2022-09-12. PMID:36094619. |
the pathophysiology of schizophrenia involves abnormal reward processing, thought to be due to disrupted striatal and dopaminergic function. |
2022-09-12 |
2023-08-14 |
human |
| Felix Brandl, Franziska Knolle, Mihai Avram, Claudia Leucht, Igor Yakushev, Josef Priller, Stefan Leucht, Sibylle Ziegler, Klaus Wunderlich, Christian Sor. Negative symptoms, striatal dopamine, and model-free reward decision-making in schizophrenia. Brain : a journal of neurology. 2022-07-25. PMID:35875972. |
negative symptoms, striatal dopamine, and model-free reward decision-making in schizophrenia. |
2022-07-25 |
2023-08-14 |
human |
| Felix Brandl, Franziska Knolle, Mihai Avram, Claudia Leucht, Igor Yakushev, Josef Priller, Stefan Leucht, Sibylle Ziegler, Klaus Wunderlich, Christian Sor. Negative symptoms, striatal dopamine, and model-free reward decision-making in schizophrenia. Brain : a journal of neurology. 2022-07-25. PMID:35875972. |
we hypothesized that in patients with schizophrenia during psychotic remission, impaired influences of both model-based and model-free reward predictions on decision-making ('reward prediction influence', rpi) underlie negative symptoms. |
2022-07-25 |
2023-08-14 |
human |
| Sugai Liang, Yue Wu, Li Hanxiaoran, Andrew J Greenshaw, Tao L. Anhedonia in Depression and Schizophrenia: Brain Reward and Aversion Circuits. Neuropsychiatric disease and treatment. vol 18. 2022-07-15. PMID:35836582. |
anhedonia in depression and schizophrenia: brain reward and aversion circuits. |
2022-07-15 |
2023-08-14 |
Not clear |
| Sugai Liang, Yue Wu, Li Hanxiaoran, Andrew J Greenshaw, Tao L. Anhedonia in Depression and Schizophrenia: Brain Reward and Aversion Circuits. Neuropsychiatric disease and treatment. vol 18. 2022-07-15. PMID:35836582. |
here, we review the characteristics of anhedonia in depression and schizophrenia as well as shared or disorder-specific anhedonia-related alterations in reward and aversion pathways of the brain. |
2022-07-15 |
2023-08-14 |
Not clear |
| Lauren T Catalano, Jonathan K Wynn, Michael F Green, James M Gol. Reduced neural activity when anticipating social versus nonsocial rewards in schizophrenia: Preliminary evidence from an ERP study. Schizophrenia research. vol 246. 2022-06-13. PMID:35696860. |
diminished social motivation is a core feature of schizophrenia that might reflect disturbances in social reward processing. |
2022-06-13 |
2023-08-14 |
human |
| Lauren T Catalano, Jonathan K Wynn, Michael F Green, James M Gol. Reduced neural activity when anticipating social versus nonsocial rewards in schizophrenia: Preliminary evidence from an ERP study. Schizophrenia research. vol 246. 2022-06-13. PMID:35696860. |
importantly, schizophrenia participants exhibited less anticipation of social rewards relative to nonsocial rewards (spn), whereas healthy participants showed similar anticipation for both reward types. |
2022-06-13 |
2023-08-14 |
human |
| Lauren T Catalano, Jonathan K Wynn, Michael F Green, James M Gol. Reduced neural activity when anticipating social versus nonsocial rewards in schizophrenia: Preliminary evidence from an ERP study. Schizophrenia research. vol 246. 2022-06-13. PMID:35696860. |
together, these findings provide preliminary evidence for intact social reward "liking" and impaired "wanting" in schizophrenia. |
2022-06-13 |
2023-08-14 |
human |
| Alexandra Münster, Susanne Sommer, Diana Kúkeľová, Hannes Sigrist, Eliza Koros, Serena Deiana, Klaus Klinder, Tamara Baader-Pagler, Svenja Mayer-Wrangowski, Boris Ferger, Tom Bretschneider, Christopher R Pryce, Wolfgang Hauber, Moritz von Heimendah. Effects of GPR139 agonism on effort expenditure for food reward in rodent models: Evidence for pro-motivational actions. Neuropharmacology. 2022-05-13. PMID:35561791. |
apathy, deficiency of motivation including willingness to exert effort for reward, is a common symptom in many psychiatric and neurological disorders, including depression and schizophrenia. |
2022-05-13 |
2023-08-13 |
Not clear |
| Erin K Moran, Adam J Culbreth, Deanna M Barc. Anhedonia in Schizophrenia. Current topics in behavioral neurosciences. 2022-05-03. PMID:35503596. |
here we detail these mechanisms for emotional and motivational impairment in people with schizophrenia including: (1) initial response to reward; (2) reward anticipation; (3) reward learning; (4) effort-cost decision-making; (5) working memory and cognitive control. |
2022-05-03 |
2023-08-13 |
Not clear |
| Lucinda J Speers, Robert Schmidt, David K Bilke. Aberrant phase precession of lateral septal cells in a maternal immune activation model of schizophrenia risk may disrupt the integration of location with reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-04-09. PMID:35396329. |
aberrant phase precession of lateral septal cells in a maternal immune activation model of schizophrenia risk may disrupt the integration of location with reward. |
2022-04-09 |
2023-08-13 |
rat |
| Lucinda J Speers, Robert Schmidt, David K Bilke. Aberrant phase precession of lateral septal cells in a maternal immune activation model of schizophrenia risk may disrupt the integration of location with reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-04-09. PMID:35396329. |
spatial memory and reward processing are known to be disrupted in schizophrenia. |
2022-04-09 |
2023-08-13 |
rat |
| Lucinda J Speers, Robert Schmidt, David K Bilke. Aberrant phase precession of lateral septal cells in a maternal immune activation model of schizophrenia risk may disrupt the integration of location with reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-04-09. PMID:35396329. |
since the lateral septum (ls) may play an important role in the integration of location and reward, we examined the effect of maternal immune activation (mia), a known schizophrenia risk factor, on spatial representation in the rat ls. |
2022-04-09 |
2023-08-13 |
rat |
| Lucinda J Speers, Robert Schmidt, David K Bilke. Aberrant phase precession of lateral septal cells in a maternal immune activation model of schizophrenia risk may disrupt the integration of location with reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-04-09. PMID:35396329. |
these findings suggest that a schizophrenia risk factor disrupts the phase-based encoding of location-reward relationships in the ls, potentially smearing reward representations across space. |
2022-04-09 |
2023-08-13 |
rat |
| Xiaoyan Cheng, Lingling Wang, Qinyu Lv, Haisu Wu, Xinxin Huang, Jie Yuan, Xirong Sun, Xudong Zhao, Chao Yan, Zhenghui Y. Reduced learning bias towards the reward context in medication-naive first-episode schizophrenia patients. BMC psychiatry. vol 22. issue 1. 2022-02-17. PMID:35172748. |
reduced learning bias towards the reward context in medication-naive first-episode schizophrenia patients. |
2022-02-17 |
2023-08-13 |
Not clear |
| Karel Kieslich, Vincent Valton, Jonathan P Roise. Pleasure, Reward Value, Prediction Error and Anhedonia. Current topics in behavioral neurosciences. 2022-02-14. PMID:35156187. |
overall, there is reliable evidence that depression and schizophrenia are associated with disrupted reward processing. |
2022-02-14 |
2023-08-13 |
Not clear |