Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Jung Suk Lee, Suwon Jung, Il Ho Park, Jae-Jin Ki. Neural Basis of Anhedonia and Amotivation in Patients with Schizophrenia: The Role of Reward System. Current neuropharmacology. vol 13. issue 6. 2016-09-09. PMID:26630955. |
neural basis of anhedonia and amotivation in patients with schizophrenia: the role of reward system. |
2016-09-09 |
2023-08-13 |
Not clear |
Jung Suk Lee, Suwon Jung, Il Ho Park, Jae-Jin Ki. Neural Basis of Anhedonia and Amotivation in Patients with Schizophrenia: The Role of Reward System. Current neuropharmacology. vol 13. issue 6. 2016-09-09. PMID:26630955. |
a further analysis into the neuroimaging findings of schizophrenia shows that the neural correlates overlap in the reward network including the ventral striatum, anterior cingulate cortex and orbitofrontal cortex. |
2016-09-09 |
2023-08-13 |
Not clear |
Matthew A Albrecht, James A Waltz, James F Cavanagh, Michael J Frank, James M Gol. Reduction of Pavlovian Bias in Schizophrenia: Enhanced Effects in Clozapine-Administered Patients. PloS one. vol 11. issue 4. 2016-08-12. PMID:27044008. |
the negative symptoms of schizophrenia (sz) are associated with a pattern of reinforcement learning (rl) deficits likely related to degraded representations of reward values. |
2016-08-12 |
2023-08-13 |
Not clear |
Matthew A Albrecht, James A Waltz, James F Cavanagh, Michael J Frank, James M Gol. Reduction of Pavlovian Bias in Schizophrenia: Enhanced Effects in Clozapine-Administered Patients. PloS one. vol 11. issue 4. 2016-08-12. PMID:27044008. |
forty-five patients with schizophrenia and 30 demographically-matched controls completed a four-stimulus reinforcement learning task that crossed action ("go" or "nogo") and the valence of the optimal outcome (reward or punishment-avoidance), such that all combinations of action and outcome valence were tested. |
2016-08-12 |
2023-08-13 |
Not clear |
James M Gold, James A Waltz, Michael J Fran. Effort cost computation in schizophrenia: a commentary on the recent literature. Biological psychiatry. vol 78. issue 11. 2016-08-11. PMID:26049208. |
there is a clear preponderance of evidence suggesting that people with schizophrenia demonstrate altered effort allocation by failing to make high-effort response choices to maximize reward. |
2016-08-11 |
2023-08-13 |
Not clear |
Anja Richter, Aleksandra Petrovic, Esther K Diekhof, Sarah Trost, Sarah Wolter, Oliver Grube. Hyperresponsivity and impaired prefrontal control of the mesolimbic reward system in schizophrenia. Journal of psychiatric research. vol 71. 2016-08-10. PMID:26522867. |
hyperresponsivity and impaired prefrontal control of the mesolimbic reward system in schizophrenia. |
2016-08-10 |
2023-08-13 |
human |
Anja Richter, Aleksandra Petrovic, Esther K Diekhof, Sarah Trost, Sarah Wolter, Oliver Grube. Hyperresponsivity and impaired prefrontal control of the mesolimbic reward system in schizophrenia. Journal of psychiatric research. vol 71. 2016-08-10. PMID:26522867. |
schizophrenia is characterized by substantial dysfunctions of reward processing, leading to detrimental consequences for decision-making. |
2016-08-10 |
2023-08-13 |
human |
Anja Richter, Aleksandra Petrovic, Esther K Diekhof, Sarah Trost, Sarah Wolter, Oliver Grube. Hyperresponsivity and impaired prefrontal control of the mesolimbic reward system in schizophrenia. Journal of psychiatric research. vol 71. 2016-08-10. PMID:26522867. |
these findings provide evidence for an increased ventral striatal activation to reward stimuli and an impaired top-down control of reward signals by prefrontal brain regions in schizophrenia. |
2016-08-10 |
2023-08-13 |
human |
R W Morris, T D Purves-Tyson, C Shannon Weickert, D Rothmond, R Lenroot, T W Weicker. Testosterone and reward prediction-errors in healthy men and men with schizophrenia. Schizophrenia research. vol 168. issue 3. 2016-08-03. PMID:26232868. |
testosterone and reward prediction-errors in healthy men and men with schizophrenia. |
2016-08-03 |
2023-08-13 |
human |
R W Morris, T D Purves-Tyson, C Shannon Weickert, D Rothmond, R Lenroot, T W Weicker. Testosterone and reward prediction-errors in healthy men and men with schizophrenia. Schizophrenia research. vol 168. issue 3. 2016-08-03. PMID:26232868. |
sex hormones impact reward processing, which is dysfunctional in schizophrenia; however, the degree to which testosterone levels relate to reward-related brain activity in healthy men and the extent to which this relationship may be altered in men with schizophrenia has not been determined. |
2016-08-03 |
2023-08-13 |
human |
Jared W Young, Mary E Kamenski, Kerin K Higa, Gregory A Light, Mark A Geyer, Xianjin Zho. GlyT-1 Inhibition Attenuates Attentional But Not Learning or Motivational Deficits of the Sp4 Hypomorphic Mouse Model Relevant to Psychiatric Disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 12. 2016-08-02. PMID:25907107. |
these deficits may stem from affected anticipatory reward, analogous to anhedonia in patients with schizophrenia and other psychiatric disorders. |
2016-08-02 |
2023-08-13 |
mouse |
Joe J Simon, Sheila A Cordeiro, Marc-André Weber, Hans-Christoph Friederich, Robert C Wolf, Matthias Weisbrod, Stefan Kaise. Reward System Dysfunction as a Neural Substrate of Symptom Expression Across the General Population and Patients With Schizophrenia. Schizophrenia bulletin. vol 41. issue 6. 2016-07-20. PMID:26006262. |
reward system dysfunction as a neural substrate of symptom expression across the general population and patients with schizophrenia. |
2016-07-20 |
2023-08-13 |
human |
Joe J Simon, Sheila A Cordeiro, Marc-André Weber, Hans-Christoph Friederich, Robert C Wolf, Matthias Weisbrod, Stefan Kaise. Reward System Dysfunction as a Neural Substrate of Symptom Expression Across the General Population and Patients With Schizophrenia. Schizophrenia bulletin. vol 41. issue 6. 2016-07-20. PMID:26006262. |
dysfunctional patterns of activation in brain reward networks have been suggested as a core element in the pathophysiology of schizophrenia. |
2016-07-20 |
2023-08-13 |
human |
Matthias Kirschner, Oliver M Hager, Martin Bischof, Matthias N Hartmann-Riemer, Agne Kluge, Erich Seifritz, Philippe N Tobler, Stefan Kaise. Deficits in context-dependent adaptive coding of reward in schizophrenia. NPJ schizophrenia. vol 2. 2016-07-19. PMID:27430009. |
deficits in context-dependent adaptive coding of reward in schizophrenia. |
2016-07-19 |
2023-08-13 |
Not clear |
Matthias Kirschner, Oliver M Hager, Martin Bischof, Matthias N Hartmann-Riemer, Agne Kluge, Erich Seifritz, Philippe N Tobler, Stefan Kaise. Deficits in context-dependent adaptive coding of reward in schizophrenia. NPJ schizophrenia. vol 2. 2016-07-19. PMID:27430009. |
however, despite the fundamental significance of coding reward adaptively, no study has elucidated whether adaptive reward processing is impaired in schizophrenia. |
2016-07-19 |
2023-08-13 |
Not clear |
Matthias Kirschner, Oliver M Hager, Martin Bischof, Matthias N Hartmann-Riemer, Agne Kluge, Erich Seifritz, Philippe N Tobler, Stefan Kaise. Deficits in context-dependent adaptive coding of reward in schizophrenia. NPJ schizophrenia. vol 2. 2016-07-19. PMID:27430009. |
compared with healthy controls, patients with schizophrenia showed less efficient neural adaptation to the current reward context, which leads to imprecise neural representation of reward. |
2016-07-19 |
2023-08-13 |
Not clear |
Matthias Kirschner, Oliver M Hager, Martin Bischof, Matthias N Hartmann-Riemer, Agne Kluge, Erich Seifritz, Philippe N Tobler, Stefan Kaise. Deficits in context-dependent adaptive coding of reward in schizophrenia. NPJ schizophrenia. vol 2. 2016-07-19. PMID:27430009. |
our results suggest that some of the deficits in reward processing in schizophrenia might be due to inefficient neural adaptation to the current reward context. |
2016-07-19 |
2023-08-13 |
Not clear |
Jiao Wang, Jia Huang, Xin-Hua Yang, Simon S Y Lui, Eric F C Cheung, Raymond C K Cha. Anhedonia in schizophrenia: Deficits in both motivation and hedonic capacity. Schizophrenia research. vol 168. issue 1-2. 2016-07-06. PMID:26185892. |
as the reward magnitude and the estimated reward value increased, unlike healthy controls, schizophrenia patients with prominent negative symptoms did not increase their hard task choices. |
2016-07-06 |
2023-08-13 |
human |
Jiao Wang, Jia Huang, Xin-Hua Yang, Simon S Y Lui, Eric F C Cheung, Raymond C K Cha. Anhedonia in schizophrenia: Deficits in both motivation and hedonic capacity. Schizophrenia research. vol 168. issue 1-2. 2016-07-06. PMID:26185892. |
the pleasure experience rating after obtaining the actual reward was positively correlated with two pleasure experience scales in schizophrenia patients. |
2016-07-06 |
2023-08-13 |
human |
Oliver M Hager, Matthias Kirschner, Martin Bischof, Matthias N Hartmann-Riemer, Agne Kluge, Erich Seifritz, Philippe N Tobler, Stefan Kaise. Reward-dependent modulation of working memory is associated with negative symptoms in schizophrenia. Schizophrenia research. vol 168. issue 1-2. 2016-07-06. PMID:26362736. |
the negative symptoms of schizophrenia have been associated with altered neural activity during both reward processing and cognitive processing. |
2016-07-06 |
2023-08-13 |
Not clear |