| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthew A Albrecht, James A Waltz, James F Cavanagh, Michael J Frank, James M Gol. Reduction of Pavlovian Bias in Schizophrenia: Enhanced Effects in Clozapine-Administered Patients. PloS one. vol 11. issue 4. 2016-08-12. PMID:27044008. |
forty-five patients with schizophrenia and 30 demographically-matched controls completed a four-stimulus reinforcement learning task that crossed action ("go" or "nogo") and the valence of the optimal outcome (reward or punishment-avoidance), such that all combinations of action and outcome valence were tested. |
2016-08-12 |
2023-08-13 |
Not clear |
| James M Gold, James A Waltz, Michael J Fran. Effort cost computation in schizophrenia: a commentary on the recent literature. Biological psychiatry. vol 78. issue 11. 2016-08-11. PMID:26049208. |
there is a clear preponderance of evidence suggesting that people with schizophrenia demonstrate altered effort allocation by failing to make high-effort response choices to maximize reward. |
2016-08-11 |
2023-08-13 |
Not clear |
| Anja Richter, Aleksandra Petrovic, Esther K Diekhof, Sarah Trost, Sarah Wolter, Oliver Grube. Hyperresponsivity and impaired prefrontal control of the mesolimbic reward system in schizophrenia. Journal of psychiatric research. vol 71. 2016-08-10. PMID:26522867. |
hyperresponsivity and impaired prefrontal control of the mesolimbic reward system in schizophrenia. |
2016-08-10 |
2023-08-13 |
human |
| Anja Richter, Aleksandra Petrovic, Esther K Diekhof, Sarah Trost, Sarah Wolter, Oliver Grube. Hyperresponsivity and impaired prefrontal control of the mesolimbic reward system in schizophrenia. Journal of psychiatric research. vol 71. 2016-08-10. PMID:26522867. |
schizophrenia is characterized by substantial dysfunctions of reward processing, leading to detrimental consequences for decision-making. |
2016-08-10 |
2023-08-13 |
human |
| Anja Richter, Aleksandra Petrovic, Esther K Diekhof, Sarah Trost, Sarah Wolter, Oliver Grube. Hyperresponsivity and impaired prefrontal control of the mesolimbic reward system in schizophrenia. Journal of psychiatric research. vol 71. 2016-08-10. PMID:26522867. |
these findings provide evidence for an increased ventral striatal activation to reward stimuli and an impaired top-down control of reward signals by prefrontal brain regions in schizophrenia. |
2016-08-10 |
2023-08-13 |
human |
| R W Morris, T D Purves-Tyson, C Shannon Weickert, D Rothmond, R Lenroot, T W Weicker. Testosterone and reward prediction-errors in healthy men and men with schizophrenia. Schizophrenia research. vol 168. issue 3. 2016-08-03. PMID:26232868. |
testosterone and reward prediction-errors in healthy men and men with schizophrenia. |
2016-08-03 |
2023-08-13 |
human |
| R W Morris, T D Purves-Tyson, C Shannon Weickert, D Rothmond, R Lenroot, T W Weicker. Testosterone and reward prediction-errors in healthy men and men with schizophrenia. Schizophrenia research. vol 168. issue 3. 2016-08-03. PMID:26232868. |
sex hormones impact reward processing, which is dysfunctional in schizophrenia; however, the degree to which testosterone levels relate to reward-related brain activity in healthy men and the extent to which this relationship may be altered in men with schizophrenia has not been determined. |
2016-08-03 |
2023-08-13 |
human |
| Jared W Young, Mary E Kamenski, Kerin K Higa, Gregory A Light, Mark A Geyer, Xianjin Zho. GlyT-1 Inhibition Attenuates Attentional But Not Learning or Motivational Deficits of the Sp4 Hypomorphic Mouse Model Relevant to Psychiatric Disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 12. 2016-08-02. PMID:25907107. |
these deficits may stem from affected anticipatory reward, analogous to anhedonia in patients with schizophrenia and other psychiatric disorders. |
2016-08-02 |
2023-08-13 |
mouse |
| Joe J Simon, Sheila A Cordeiro, Marc-André Weber, Hans-Christoph Friederich, Robert C Wolf, Matthias Weisbrod, Stefan Kaise. Reward System Dysfunction as a Neural Substrate of Symptom Expression Across the General Population and Patients With Schizophrenia. Schizophrenia bulletin. vol 41. issue 6. 2016-07-20. PMID:26006262. |
reward system dysfunction as a neural substrate of symptom expression across the general population and patients with schizophrenia. |
2016-07-20 |
2023-08-13 |
human |
| Joe J Simon, Sheila A Cordeiro, Marc-André Weber, Hans-Christoph Friederich, Robert C Wolf, Matthias Weisbrod, Stefan Kaise. Reward System Dysfunction as a Neural Substrate of Symptom Expression Across the General Population and Patients With Schizophrenia. Schizophrenia bulletin. vol 41. issue 6. 2016-07-20. PMID:26006262. |
dysfunctional patterns of activation in brain reward networks have been suggested as a core element in the pathophysiology of schizophrenia. |
2016-07-20 |
2023-08-13 |
human |
| Matthias Kirschner, Oliver M Hager, Martin Bischof, Matthias N Hartmann-Riemer, Agne Kluge, Erich Seifritz, Philippe N Tobler, Stefan Kaise. Deficits in context-dependent adaptive coding of reward in schizophrenia. NPJ schizophrenia. vol 2. 2016-07-19. PMID:27430009. |
deficits in context-dependent adaptive coding of reward in schizophrenia. |
2016-07-19 |
2023-08-13 |
Not clear |
| Matthias Kirschner, Oliver M Hager, Martin Bischof, Matthias N Hartmann-Riemer, Agne Kluge, Erich Seifritz, Philippe N Tobler, Stefan Kaise. Deficits in context-dependent adaptive coding of reward in schizophrenia. NPJ schizophrenia. vol 2. 2016-07-19. PMID:27430009. |
however, despite the fundamental significance of coding reward adaptively, no study has elucidated whether adaptive reward processing is impaired in schizophrenia. |
2016-07-19 |
2023-08-13 |
Not clear |
| Matthias Kirschner, Oliver M Hager, Martin Bischof, Matthias N Hartmann-Riemer, Agne Kluge, Erich Seifritz, Philippe N Tobler, Stefan Kaise. Deficits in context-dependent adaptive coding of reward in schizophrenia. NPJ schizophrenia. vol 2. 2016-07-19. PMID:27430009. |
compared with healthy controls, patients with schizophrenia showed less efficient neural adaptation to the current reward context, which leads to imprecise neural representation of reward. |
2016-07-19 |
2023-08-13 |
Not clear |
| Matthias Kirschner, Oliver M Hager, Martin Bischof, Matthias N Hartmann-Riemer, Agne Kluge, Erich Seifritz, Philippe N Tobler, Stefan Kaise. Deficits in context-dependent adaptive coding of reward in schizophrenia. NPJ schizophrenia. vol 2. 2016-07-19. PMID:27430009. |
our results suggest that some of the deficits in reward processing in schizophrenia might be due to inefficient neural adaptation to the current reward context. |
2016-07-19 |
2023-08-13 |
Not clear |
| Jiao Wang, Jia Huang, Xin-Hua Yang, Simon S Y Lui, Eric F C Cheung, Raymond C K Cha. Anhedonia in schizophrenia: Deficits in both motivation and hedonic capacity. Schizophrenia research. vol 168. issue 1-2. 2016-07-06. PMID:26185892. |
as the reward magnitude and the estimated reward value increased, unlike healthy controls, schizophrenia patients with prominent negative symptoms did not increase their hard task choices. |
2016-07-06 |
2023-08-13 |
human |
| Jiao Wang, Jia Huang, Xin-Hua Yang, Simon S Y Lui, Eric F C Cheung, Raymond C K Cha. Anhedonia in schizophrenia: Deficits in both motivation and hedonic capacity. Schizophrenia research. vol 168. issue 1-2. 2016-07-06. PMID:26185892. |
the pleasure experience rating after obtaining the actual reward was positively correlated with two pleasure experience scales in schizophrenia patients. |
2016-07-06 |
2023-08-13 |
human |
| Oliver M Hager, Matthias Kirschner, Martin Bischof, Matthias N Hartmann-Riemer, Agne Kluge, Erich Seifritz, Philippe N Tobler, Stefan Kaise. Reward-dependent modulation of working memory is associated with negative symptoms in schizophrenia. Schizophrenia research. vol 168. issue 1-2. 2016-07-06. PMID:26362736. |
the negative symptoms of schizophrenia have been associated with altered neural activity during both reward processing and cognitive processing. |
2016-07-06 |
2023-08-13 |
Not clear |
| Oliver M Hager, Matthias Kirschner, Martin Bischof, Matthias N Hartmann-Riemer, Agne Kluge, Erich Seifritz, Philippe N Tobler, Stefan Kaise. Reward-dependent modulation of working memory is associated with negative symptoms in schizophrenia. Schizophrenia research. vol 168. issue 1-2. 2016-07-06. PMID:26362736. |
the interaction did not differ significantly between the patient group and a healthy control group, suggesting that patients with schizophrenia are on average able to integrate reward information and utilize this information to maximize cognitive performance. |
2016-07-06 |
2023-08-13 |
Not clear |
| Stephanie M Gorka, K Luan Phan, Stewart A Shankma. Convergence of EEG and fMRI measures of reward anticipation. Biological psychology. vol 112. 2016-06-27. PMID:26394333. |
this suggests that the two measures may similarly capture pfc functioning, which is noteworthy given the role of these regions in reward processing and the pathophysiology of disorders such as depression and schizophrenia. |
2016-06-27 |
2023-08-13 |
human |
| Mette Ø Nielsen, Egill Rostrup, Sanne Wulff, Birte Glenthøj, Bjørn H Ebdru. Striatal Reward Activity and Antipsychotic-Associated Weight Change in Patients With Schizophrenia Undergoing Initial Treatment. JAMA psychiatry. vol 73. issue 2. 2016-06-17. PMID:26747088. |
striatal reward activity and antipsychotic-associated weight change in patients with schizophrenia undergoing initial treatment. |
2016-06-17 |
2023-08-13 |
Not clear |