| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dag H Yasui, Sailaja Peddada, Mark C Bieda, Roxanne O Vallero, Amber Hogart, Raman P Nagarajan, Karen N Thatcher, Peggy J Farnham, Janine M Lasall. Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 49. 2008-01-18. PMID:18042715. |
mutations in mecp2 cause the autism-spectrum disorder rett syndrome. |
2008-01-18 |
2023-08-12 |
Not clear |
| Karen N Thatcher, Janine M LaSall. Dynamic changes in Histone H3 lysine 9 acetylation localization patterns during neuronal maturation require MeCP2. Epigenetics. vol 1. issue 1. 2008-01-16. PMID:17464364. |
mutations within the gene encoding methyl cpg binding protein 2 (mecp2) cause the autism-spectrum neurodevelopmental disorder rett syndrome (rtt). |
2008-01-16 |
2023-08-12 |
mouse |
| Raman P Nagarajan, Amber R Hogart, Ynnez Gwye, Michelle R Martin, Janine M LaSall. Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylation. Epigenetics. vol 1. issue 4. 2008-01-16. PMID:17486179. |
mutations in mecp2, encoding methyl cpg binding protein 2 (mecp2), cause most cases of rett syndrome (rtt), an x-linked neurodevelopmental disorder. |
2008-01-16 |
2023-08-12 |
Not clear |
| Janine M LaSall. The Odyssey of MeCP2 and parental imprinting. Epigenetics. vol 2. issue 1. 2008-01-16. PMID:17965611. |
methyl cpg binding protein 2 (mecp2) selectively binds to methylated dna and mutations in the mecp2 cause the autism-spectrum neurodevelopmental disorder rett syndrome. |
2008-01-16 |
2023-08-12 |
Not clear |
| Rocio G Urdinguio, Irene Pino, Santiago Ropero, Mario F Fraga, Manel Estelle. Histone H3 and H4 modification profiles in a Rett syndrome mouse model. Epigenetics. vol 2. issue 1. 2008-01-16. PMID:17965622. |
rett syndrome (rtt) is a complex neurodevelopmental disorder that has been associated with mutations of methyl-cpg binding protein 2 (mecp2). |
2008-01-16 |
2023-08-12 |
mouse |
| Xinyu Zhao, ChangHui Pak, Richard D Smrt, Peng Ji. Epigenetics and Neural developmental disorders: Washington DC, September 18 and 19, 2006. Epigenetics. vol 2. issue 2. 2008-01-16. PMID:17965627. |
rett syndrome, the most common form of mental retardation in young girls, is due to l mutation of mecp2, encoding a methylated dna binding protein that translates dna methylation into gene repression. |
2008-01-16 |
2023-08-12 |
Not clear |
| Elisa Scala, Ilaria Longo, Federica Ottimo, Caterina Speciale, Katia Sampieri, Eleni Katzaki, Rosangela Artuso, Maria Antonietta Mencarelli, Tatiana D'Ambrogio, Giuseppina Vonella, Michele Zappella, Giuseppe Hayek, Agatino Battaglia, Francesca Mari, Alessandra Renieri, Francesca Arian. MECP2 deletions and genotype-phenotype correlation in Rett syndrome. American journal of medical genetics. Part A. vol 143A. issue 23. 2008-01-16. PMID:17968969. |
mecp2 deletions and genotype-phenotype correlation in rett syndrome. |
2008-01-16 |
2023-08-12 |
Not clear |
| Schahram Akbarian, Yan Jiang, Genevieve Lafore. The molecular pathology of Rett syndrome: synopsis and update. Neuromolecular medicine. vol 8. issue 4. 2008-01-11. PMID:17028371. |
genetic mutations of the x-linked gene mecp2, encoding methyl-cpg-binding protein 2, cause rett syndrome (rtt) and other neurological disorders. |
2008-01-11 |
2023-08-12 |
mouse |
| A Djarmati, V Dobricić, M Kecmanović, P Marsh, J Jancić-Stefanović, C Klein, M Djurić, S Roma. MECP2 mutations in Serbian Rett syndrome patients. Acta neurologica Scandinavica. vol 116. issue 6. 2008-01-11. PMID:17986102. |
mecp2 mutations in serbian rett syndrome patients. |
2008-01-11 |
2023-08-12 |
Not clear |
| A Djarmati, V Dobricić, M Kecmanović, P Marsh, J Jancić-Stefanović, C Klein, M Djurić, S Roma. MECP2 mutations in Serbian Rett syndrome patients. Acta neurologica Scandinavica. vol 116. issue 6. 2008-01-11. PMID:17986102. |
eight years ago, the mecp2 gene was associated with the devastating clinical features observed in rett syndrome patients. |
2008-01-11 |
2023-08-12 |
Not clear |
| Maria Chahrour, Huda Y Zoghb. The story of Rett syndrome: from clinic to neurobiology. Neuron. vol 56. issue 3. 2008-01-08. PMID:17988628. |
the postnatal neurodevelopmental disorder rett syndrome (rtt) is caused by mutations in the gene encoding methyl-cpg binding protein 2 (mecp2), a transcriptional repressor involved in chromatin remodeling and the modulation of rna splicing. |
2008-01-08 |
2023-08-12 |
mouse |
| Lisa Helbling Chadwick, Paul A Wad. MeCP2 in Rett syndrome: transcriptional repressor or chromatin architectural protein? Current opinion in genetics & development. vol 17. issue 2. 2007-12-13. PMID:17317146. |
mecp2 in rett syndrome: transcriptional repressor or chromatin architectural protein? |
2007-12-13 |
2023-08-12 |
Not clear |
| Lisa Helbling Chadwick, Paul A Wad. MeCP2 in Rett syndrome: transcriptional repressor or chromatin architectural protein? Current opinion in genetics & development. vol 17. issue 2. 2007-12-13. PMID:17317146. |
rett syndrome is a progressive neurological disorder caused by mutations in the methyl-dna binding protein mecp2. |
2007-12-13 |
2023-08-12 |
Not clear |
| Lisa Helbling Chadwick, Paul A Wad. MeCP2 in Rett syndrome: transcriptional repressor or chromatin architectural protein? Current opinion in genetics & development. vol 17. issue 2. 2007-12-13. PMID:17317146. |
the longstanding model depicting mecp2 as a transcriptional repressor predicts that the rett syndrome phenotype probably results from misregulation of mecp2 target genes. |
2007-12-13 |
2023-08-12 |
Not clear |
| Michael Ogier, Hong Wang, Elizabeth Hong, Qifang Wang, Michael E Greenberg, David M Kat. Brain-derived neurotrophic factor expression and respiratory function improve after ampakine treatment in a mouse model of Rett syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 40. 2007-11-26. PMID:17913925. |
rett syndrome (rtt) is caused by loss-of-function mutations in the gene encoding methyl-cpg-binding protein 2 (mecp2). |
2007-11-26 |
2023-08-12 |
mouse |
| Noriko Itaba-Matsumoto, Shinji Maegawa, Hidehisa Yamagata, Ikuko Kondo, Mitsuo Oshimura, Eiji Nanb. Imprinting status of paternally imprinted DLX5 gene in Japanese patients with Rett syndrome. Brain & development. vol 29. issue 8. 2007-11-07. PMID:17363207. |
rett syndrome (rtt) is an x-linked severe neurodevelopmental disorder mostly affecting female and is mainly caused by mutations of methyl-cpg-binding protein 2 gene (mecp2). |
2007-11-07 |
2023-08-12 |
Not clear |
| Birgitt Schüle, Hong Hua Li, Claudia Fisch-Kohl, Carolin Purmann, Uta Franck. DLX5 and DLX6 expression is biallelic and not modulated by MeCP2 deficiency. American journal of human genetics. vol 81. issue 3. 2007-10-04. PMID:17701895. |
recent literature claimed that the developmental homeobox gene dlx5 is imprinted and that its imprinting status is modulated by mecp2, leading to biallelic expression in rett syndrome and twofold overexpression of dlx5 and dlx6 in mecp2-null mice. |
2007-10-04 |
2023-08-12 |
mouse |
| Birgitt Schüle, Hong Hua Li, Claudia Fisch-Kohl, Carolin Purmann, Uta Franck. DLX5 and DLX6 expression is biallelic and not modulated by MeCP2 deficiency. American journal of human genetics. vol 81. issue 3. 2007-10-04. PMID:17701895. |
the conclusion that dlx5 is a direct target of mecp2 has implications for research on the molecular bases of rett syndrome, autism, and genomic imprinting. |
2007-10-04 |
2023-08-12 |
mouse |
| Chun-Yan Xi, Hong-Wei Ma, Yao Lu, Yun-Jing Zhao, Tian-Yi Hua, Yaru Zhao, Yao-Hua J. MeCP2 gene mutation analysis in autistic boys with developmental regression. Psychiatric genetics. vol 17. issue 2. 2007-09-26. PMID:17413451. |
the rett syndrome gene was identified as mecp2 gene on xq28, a powerful transcriptional repressor. |
2007-09-26 |
2023-08-12 |
Not clear |
| Richard D Smrt, Julialea Eaves-Egenes, Basam Z Barkho, Nicholas J Santistevan, Chunmei Zhao, James B Aimone, Fred H Gage, Xinyu Zha. Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons. Neurobiology of disease. vol 27. issue 1. 2007-09-06. PMID:17532643. |
it is well known that rett syndrome, a severe postnatal childhood neurological disorder, is mostly caused by mutations in the mecp2 gene. |
2007-09-06 |
2023-08-12 |
mouse |