| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chia-Ho Pan, Shihjen Tsa. Early intervention with psychostimulants or antidepressants to increase methyl-CpG-binding protein 2 (MeCP2) expressions: a potential therapy for Rett syndrome. Medical science monitor : international medical journal of experimental and clinical research. vol 18. issue 1. 2012-04-23. PMID:22207122. |
early intervention with psychostimulants or antidepressants to increase methyl-cpg-binding protein 2 (mecp2) expressions: a potential therapy for rett syndrome. |
2012-04-23 |
2023-08-12 |
Not clear |
| Elisa S Na, Erika D Nelson, Megumi Adachi, Anita E Autry, Melissa A Mahgoub, Ege T Kavalali, Lisa M Monteggi. A mouse model for MeCP2 duplication syndrome: MeCP2 overexpression impairs learning and memory and synaptic transmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 9. 2012-04-20. PMID:22378884. |
rett syndrome and mecp2 duplication syndrome are neurodevelopmental disorders that arise from loss-of-function and gain-of-function alterations in methyl-cpg binding protein 2 (mecp2) expression, respectively. |
2012-04-20 |
2023-08-12 |
mouse |
| Eri Kawasaki, Yasunori Mishima, Takahiko Ito, Asuka Ito, Hikari Takaseya, Naomitsu Kameyama, Hisato Fukugasako, Kazuo Ushijim. [Anesthetic management of a patient with Rett syndrome associated with trismus and apnea attacks]. Masui. The Japanese journal of anesthesiology. vol 61. issue 1. 2012-04-17. PMID:22338870. |
rett syndrome (rtt) is a congenital neurological disorder associated with mutations in the gene encoding mecp2 on the x chromosome. |
2012-04-17 |
2023-08-12 |
Not clear |
| Mark D McCauley, Tiannan Wang, Elise Mike, Jose Herrera, David L Beavers, Teng-Wei Huang, Christopher S Ward, Steven Skinner, Alan K Percy, Daniel G Glaze, Xander H T Wehrens, Jeffrey L Neu. Pathogenesis of lethal cardiac arrhythmias in Mecp2 mutant mice: implication for therapy in Rett syndrome. Science translational medicine. vol 3. issue 113. 2012-04-16. PMID:22174313. |
pathogenesis of lethal cardiac arrhythmias in mecp2 mutant mice: implication for therapy in rett syndrome. |
2012-04-16 |
2023-08-12 |
mouse |
| Mark D McCauley, Tiannan Wang, Elise Mike, Jose Herrera, David L Beavers, Teng-Wei Huang, Christopher S Ward, Steven Skinner, Alan K Percy, Daniel G Glaze, Xander H T Wehrens, Jeffrey L Neu. Pathogenesis of lethal cardiac arrhythmias in Mecp2 mutant mice: implication for therapy in Rett syndrome. Science translational medicine. vol 3. issue 113. 2012-04-16. PMID:22174313. |
rett syndrome is a neurodevelopmental disorder typically caused by mutations in methyl-cpg-binding protein 2 (mecp2) in which 26% of deaths are sudden and of unknown cause. |
2012-04-16 |
2023-08-12 |
mouse |
| Mark D McCauley, Tiannan Wang, Elise Mike, Jose Herrera, David L Beavers, Teng-Wei Huang, Christopher S Ward, Steven Skinner, Alan K Percy, Daniel G Glaze, Xander H T Wehrens, Jeffrey L Neu. Pathogenesis of lethal cardiac arrhythmias in Mecp2 mutant mice: implication for therapy in Rett syndrome. Science translational medicine. vol 3. issue 113. 2012-04-16. PMID:22174313. |
genetic deletion of mecp2 function in only the nervous system was sufficient to cause long qtc and ventricular tachycardia, implicating neuronally mediated changes to cardiac electrical conduction as a potential cause of ventricular tachycardia in rett syndrome. |
2012-04-16 |
2023-08-12 |
mouse |
| Mark D McCauley, Tiannan Wang, Elise Mike, Jose Herrera, David L Beavers, Teng-Wei Huang, Christopher S Ward, Steven Skinner, Alan K Percy, Daniel G Glaze, Xander H T Wehrens, Jeffrey L Neu. Pathogenesis of lethal cardiac arrhythmias in Mecp2 mutant mice: implication for therapy in Rett syndrome. Science translational medicine. vol 3. issue 113. 2012-04-16. PMID:22174313. |
the standard therapy for prolonged qtc in rett syndrome, β-adrenergic receptor blockers, did not prevent ventricular tachycardia in mecp2(null/y) mice. |
2012-04-16 |
2023-08-12 |
mouse |
| Somasish Ghosh Dastidar, Farah H Bardai, Chi Ma, Valerie Price, Varun Rawat, Pragya Verma, Vinodh Narayanan, Santosh R D'Mell. Isoform-specific toxicity of Mecp2 in postmitotic neurons: suppression of neurotoxicity by FoxG1. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 8. 2012-04-16. PMID:22357867. |
the methyl-cpg binding protein 2 (mecp2) is a widely expressed protein, the mutations of which cause rett syndrome. |
2012-04-16 |
2023-08-12 |
mouse |
| Hai-yan Zhu, Ya-li Hu, Rui-fang Zhu, Ying Yang, Xiang-yu Zhu, Wan-jun Wang, Hong-lei Dua. [Molecular genetic study of MECP2 gene for a patient with typical Rett syndrome]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. vol 28. issue 6. 2012-04-12. PMID:22161092. |
[molecular genetic study of mecp2 gene for a patient with typical rett syndrome]. |
2012-04-12 |
2023-08-12 |
Not clear |
| Hai-yan Zhu, Ya-li Hu, Rui-fang Zhu, Ying Yang, Xiang-yu Zhu, Wan-jun Wang, Hong-lei Dua. [Molecular genetic study of MECP2 gene for a patient with typical Rett syndrome]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. vol 28. issue 6. 2012-04-12. PMID:22161092. |
to provide genetic diagnosis and counseling for a 2-year-old girl with typical rett syndrome through analyzing the methyl-cpg binding protein 2 (mecp2) gene. |
2012-04-12 |
2023-08-12 |
Not clear |
| Malaika K Singleton, Michael L Gonzales, Karen N Leung, Dag H Yasui, Diane I Schroeder, Keith Dunaway, Janine M LaSall. MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation. Neurobiology of disease. vol 43. issue 1. 2012-04-09. PMID:21420494. |
mutations in mecp2, encoding methyl cpg binding protein 2, cause the neurodevelopmental disorder rett syndrome. |
2012-04-09 |
2023-08-12 |
mouse |
| K Laurence Jost, Andrea Rottach, Manuela Milden, Bianca Bertulat, Annette Becker, Patricia Wolf, Juan Sandoval, Paolo Petazzi, Dori Huertas, Manel Esteller, Elisabeth Kremmer, Heinrich Leonhardt, M Cristina Cardos. Generation and characterization of rat and mouse monoclonal antibodies specific for MeCP2 and their use in X-inactivation studies. PloS one. vol 6. issue 11. 2012-04-09. PMID:22140431. |
this is underscored by the fact that in rett syndrome, a neurological disease, 80% of patients carry a mutation in the mecp2 gene. |
2012-04-09 |
2023-08-12 |
mouse |
| Rajni Khajuria, Neerja Gupta, Savita Sapra, Sheffali Gulati, Manju Ghosh, Veena Kalra, Madhulika Kabr. Novel non-identical MECP2 mutations in Rett syndrome family: a rare presentation. Brain & development. vol 34. issue 1. 2012-03-30. PMID:21300488. |
novel non-identical mecp2 mutations in rett syndrome family: a rare presentation. |
2012-03-30 |
2023-08-12 |
Not clear |
| Rajni Khajuria, Neerja Gupta, Savita Sapra, Sheffali Gulati, Manju Ghosh, Veena Kalra, Madhulika Kabr. Novel non-identical MECP2 mutations in Rett syndrome family: a rare presentation. Brain & development. vol 34. issue 1. 2012-03-30. PMID:21300488. |
rett syndrome (rs), an x-linked neurodevelopmental disorder and the common cause of mental retardation in females, is caused by methyl cpg binding protein 2 (mecp2) gene mutations with a frequency of more than 95% in classical rett patients. |
2012-03-30 |
2023-08-12 |
Not clear |
| Steven W Long, Jenny Y Y Ooi, Peter M Yau, Peter L Jone. A brain-derived MeCP2 complex supports a role for MeCP2 in RNA processing. Bioscience reports. vol 31. issue 5. 2012-03-26. PMID:21070191. |
mutations in mecp2 (methyl-cpg-binding protein 2) are linked to the severe postnatal neurodevelopmental disorder rtt (rett syndrome). |
2012-03-26 |
2023-08-12 |
mouse |
| Danielle A Schmid, Tao Yang, Michael Ogier, Ian Adams, Yatin Mirakhur, Qifang Wang, Stephen M Massa, Frank M Longo, David M Kat. A TrkB small molecule partial agonist rescues TrkB phosphorylation deficits and improves respiratory function in a mouse model of Rett syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 5. 2012-03-22. PMID:22302819. |
rett syndrome (rtt) results from loss-of-function mutations in the gene encoding the methyl-cpg-binding protein 2 (mecp2) and is characterized by abnormal motor, respiratory and autonomic control, cognitive impairment, autistic-like behaviors and increased risk of seizures. |
2012-03-22 |
2023-08-12 |
mouse |
| Mouna Al Husni Al Keilani, Sophie Carlier, José Groswasser, Bernard Dan, Nicolas Deconinc. Rett syndrome associated with continuous spikes and waves during sleep. Acta neurologica Belgica. vol 111. issue 4. 2012-03-20. PMID:22368975. |
the clinical picture was consistent with rett syndrome, confirmed by mecp2 mutation r133c. |
2012-03-20 |
2023-08-12 |
Not clear |
| Darren Goffin, Megan Allen, Le Zhang, Maria Amorim, I-Ting Judy Wang, Arith-Ruth S Reyes, Amy Mercado-Berton, Caroline Ong, Sonia Cohen, Linda Hu, Julie A Blendy, Gregory C Carlson, Steve J Siegel, Michael E Greenberg, Zhaolan Zho. Rett syndrome mutation MeCP2 T158A disrupts DNA binding, protein stability and ERP responses. Nature neuroscience. vol 15. issue 2. 2012-03-19. PMID:22119903. |
rett syndrome mutation mecp2 t158a disrupts dna binding, protein stability and erp responses. |
2012-03-19 |
2023-08-12 |
mouse |
| Darren Goffin, Megan Allen, Le Zhang, Maria Amorim, I-Ting Judy Wang, Arith-Ruth S Reyes, Amy Mercado-Berton, Caroline Ong, Sonia Cohen, Linda Hu, Julie A Blendy, Gregory C Carlson, Steve J Siegel, Michael E Greenberg, Zhaolan Zho. Rett syndrome mutation MeCP2 T158A disrupts DNA binding, protein stability and ERP responses. Nature neuroscience. vol 15. issue 2. 2012-03-19. PMID:22119903. |
mutations in the mecp2 gene cause the autism spectrum disorder rett syndrome (rtt). |
2012-03-19 |
2023-08-12 |
mouse |
| Mário Campos, Cristiane Pinheiro Pestana, Adriana Vaz dos Santos, Frederique Ponchel, Sarah Churchman, Cláudia Bueno Abdalla-Carvalho, Jussara Mendonça dos Santos, Flavia Lima dos Santos, Carla Gruber Gikovate, Cíntia Barros Santos-Rebouças, Márcia Mattos Gonçalves Pimente. A MECP2 missense mutation within the MBD domain in a Brazilian male with autistic disorder. Brain & development. vol 33. issue 10. 2012-03-12. PMID:21600714. |
point mutations and genomic rearrangements in the mecp2 gene are the major cause of rett syndrome (rtt), a pervasive developmental disorder affecting almost exclusively females. |
2012-03-12 |
2023-08-12 |
Not clear |