| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xin Xu, Lucas Pozzo-Mille. A novel DNA-binding feature of MeCP2 contributes to Rett syndrome. Frontiers in cellular neuroscience. vol 7. 2013-05-16. PMID:23675316. |
a novel dna-binding feature of mecp2 contributes to rett syndrome. |
2013-05-16 |
2023-08-12 |
Not clear |
| Rodney C Samaco, Christopher M McGraw, Christopher S Ward, Yaling Sun, Jeffrey L Neul, Huda Y Zoghb. Female Mecp2(+/-) mice display robust behavioral deficits on two different genetic backgrounds providing a framework for pre-clinical studies. Human molecular genetics. vol 22. issue 1. 2013-05-15. PMID:23026749. |
rett syndrome (rtt) is an x-linked neurological disorder caused by mutations in the gene encoding the transcriptional modulator methyl-cpg-binding protein 2 (mecp2). |
2013-05-15 |
2023-08-12 |
mouse |
| N Farra, W-B Zhang, P Pasceri, J H Eubanks, M W Salter, J Elli. Rett syndrome induced pluripotent stem cell-derived neurons reveal novel neurophysiological alterations. Molecular psychiatry. vol 17. issue 12. 2013-05-07. PMID:22230884. |
rett syndrome (rtt) is a neurodevelopmental autism spectrum disorder caused by mutations in the methyl-cpg-binding protein 2 (mecp2) gene. |
2013-05-07 |
2023-08-12 |
mouse |
| Elisa S Na, Erika D Nelson, Ege T Kavalali, Lisa M Monteggi. The impact of MeCP2 loss- or gain-of-function on synaptic plasticity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 1. 2013-05-02. PMID:22781840. |
the neurodevelopmental disorders rett syndrome and mecp2 duplication syndrome arise from loss-of-function and gain-of-function alterations in mecp2 expression, respectively. |
2013-05-02 |
2023-08-12 |
Not clear |
| Elisa S Na, Erika D Nelson, Ege T Kavalali, Lisa M Monteggi. The impact of MeCP2 loss- or gain-of-function on synaptic plasticity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 1. 2013-05-02. PMID:22781840. |
several animal models have been developed to recapitulate the symptoms of rett syndrome and mecp2 duplication syndrome. |
2013-05-02 |
2023-08-12 |
Not clear |
| Elisa S Na, Erika D Nelson, Ege T Kavalali, Lisa M Monteggi. The impact of MeCP2 loss- or gain-of-function on synaptic plasticity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 1. 2013-05-02. PMID:22781840. |
this review highlights the functional role of mecp2 in the brain as a regulator of synaptic and neuronal plasticity as well as its etiological role in the development of rett syndrome and mecp2 duplication syndrome. |
2013-05-02 |
2023-08-12 |
Not clear |
| Jaehoon Shin, Guo-Li Ming, Hongjun Son. By hook or by crook: multifaceted DNA-binding properties of MeCP2. Cell. vol 152. issue 5. 2013-04-26. PMID:23452844. |
two new studies reveal novel dna-binding properties of mecp2, mutations of which cause rett syndrome. |
2013-04-26 |
2023-08-12 |
Not clear |
| Jaehoon Shin, Guo-Li Ming, Hongjun Son. By hook or by crook: multifaceted DNA-binding properties of MeCP2. Cell. vol 152. issue 5. 2013-04-26. PMID:23452844. |
report critical roles for the at-hook domain of mecp2 in chromatin organization and clinical features of rett syndrome. |
2013-04-26 |
2023-08-12 |
Not clear |
| Steven Andrew Baker, Lin Chen, Angela Dawn Wilkins, Peng Yu, Olivier Lichtarge, Huda Yahya Zoghb. An AT-hook domain in MeCP2 determines the clinical course of Rett syndrome and related disorders. Cell. vol 152. issue 5. 2013-04-26. PMID:23452848. |
an at-hook domain in mecp2 determines the clinical course of rett syndrome and related disorders. |
2013-04-26 |
2023-08-12 |
mouse |
| Steven Andrew Baker, Lin Chen, Angela Dawn Wilkins, Peng Yu, Olivier Lichtarge, Huda Yahya Zoghb. An AT-hook domain in MeCP2 determines the clinical course of Rett syndrome and related disorders. Cell. vol 152. issue 5. 2013-04-26. PMID:23452848. |
mutations in the x-linked mecp2 cause rett syndrome, a devastating neurological disorder typified by a period of apparently normal development followed by loss of cognitive and psychomotor skills. |
2013-04-26 |
2023-08-12 |
mouse |
| Susan A Rose, Aleksandra Djukic, Jeffery J Jankowski, Judith F Feldman, Iris Fishman, Maria Valicenti-McDermot. Rett syndrome: an eye-tracking study of attention and recognition memory. Developmental medicine and child neurology. vol 55. issue 4. 2013-04-26. PMID:23488948. |
the aim of this study was to examine attention and recognition memory for faces and patterns in rett syndrome, a severely disabling neurodevelopmental disorder caused by mutations in the x-linked mecp2 gene. |
2013-04-26 |
2023-08-12 |
Not clear |
| Bianca Bertulat, Maria Luigia De Bonis, Floriana Della Ragione, Anne Lehmkuhl, Manuela Milden, Christian Storm, K Laurence Jost, Simona Scala, Brian Hendrich, Maurizio D'Esposito, M Cristina Cardos. MeCP2 dependent heterochromatin reorganization during neural differentiation of a novel Mecp2-deficient embryonic stem cell reporter line. PloS one. vol 7. issue 10. 2013-04-23. PMID:23112857. |
the x-linked mecp2 is a known interpreter of epigenetic information and mutated in rett syndrome, a complex neurological disease. |
2013-04-23 |
2023-08-12 |
Not clear |
| J Zhang, X Bao, G Cao, S Jiang, X Zhu, H Lu, L Jia, H Pan, S Fehr, M Davis, H Leonard, D Ravine, X W. What does the nature of the MECP2 mutation tell us about parental origin and recurrence risk in Rett syndrome? Clinical genetics. vol 82. issue 6. 2013-04-12. PMID:22182064. |
what does the nature of the mecp2 mutation tell us about parental origin and recurrence risk in rett syndrome? |
2013-04-12 |
2023-08-12 |
Not clear |
| J Zhang, X Bao, G Cao, S Jiang, X Zhu, H Lu, L Jia, H Pan, S Fehr, M Davis, H Leonard, D Ravine, X W. What does the nature of the MECP2 mutation tell us about parental origin and recurrence risk in Rett syndrome? Clinical genetics. vol 82. issue 6. 2013-04-12. PMID:22182064. |
the mecp2 mutations occurring in the severe neurological disorder rett syndrome are predominantly de novo, with rare familial cases. |
2013-04-12 |
2023-08-12 |
Not clear |
| Dhanjit Kumar Das, Sarbani Raha, Daksha Sanghavi, Anurupa Maitra, Vrajesh Udan. Spectrum of MECP2 gene mutations in a cohort of Indian patients with Rett syndrome: report of two novel mutations. Gene. vol 515. issue 1. 2013-03-18. PMID:23262346. |
spectrum of mecp2 gene mutations in a cohort of indian patients with rett syndrome: report of two novel mutations. |
2013-03-18 |
2023-08-12 |
Not clear |
| Dhanjit Kumar Das, Sarbani Raha, Daksha Sanghavi, Anurupa Maitra, Vrajesh Udan. Spectrum of MECP2 gene mutations in a cohort of Indian patients with Rett syndrome: report of two novel mutations. Gene. vol 515. issue 1. 2013-03-18. PMID:23262346. |
rett syndrome is caused by mutations within methyl cpg-binding protein 2 (mecp2) gene. |
2013-03-18 |
2023-08-12 |
Not clear |
| Chloé Delépine, Juliette Nectoux, Nadia Bahi-Buisson, Jamel Chelly, Thierry Bienven. MeCP2 deficiency is associated with impaired microtubule stability. FEBS letters. vol 587. issue 2. 2013-03-07. PMID:23238081. |
rett syndrome (rtt) is a neurodevelopmental disorder caused by mecp2 mutations. |
2013-03-07 |
2023-08-12 |
Not clear |
| Tihomir Todorov, Albena Todorova, Cristina Motoescu, Petia Dimova, Daniela Iancu, Dana Craiu, Daniela Stoian, Ligia Barbarii, Veneta Bojinova, Vanyo Mite. Spontaneous recurrent mutations and a complex rearrangement in the MECP2 gene in the light of current models of mutagenesis. Mutation research. vol 734. issue 1-2. 2013-02-19. PMID:22525432. |
mutations in the methyl-cpg-binding protein 2 (mecp2) gene are associated with rett syndrome (rtt). |
2013-02-19 |
2023-08-12 |
Not clear |
| Jun Ren, Xiuqing Ding, Gregory D Funk, John J Gree. Anxiety-related mechanisms of respiratory dysfunction in a mouse model of Rett syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 48. 2013-02-19. PMID:23197715. |
rett syndrome (rtt) is a severe neurological disorder that is associated with mutations in the methyl-cpg binding protein 2 (mecp2) gene. |
2013-02-19 |
2023-08-12 |
mouse |
| Xiu Xu, Qiong Xu, Ying Zhang, Xiaodi Zhang, Tianlin Cheng, Bingbing Wu, Yanhua Ding, Ping Lu, Jingjing Zheng, Min Zhang, Zilong Qiu, Xiang Y. A case report of Chinese brothers with inherited MECP2-containing duplication: autism and intellectual disability, but not seizures or respiratory infections. BMC medical genetics. vol 13. 2013-02-01. PMID:22909152. |
one such gene is the transcription factor mecp2, whose loss of function in females results in rett syndrome, while its duplication in males results in developmental delay and autism. |
2013-02-01 |
2023-08-12 |
Not clear |