| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ridhima Vij, Hosu Kim, Hyeonggeun Park, Thanh Cheng, Djamchid Lotfi, Donna Chan. Functional recovery of a 41-year-old quadriplegic spinal cord injury patient following multiple intravenous infusions of autologous adipose-derived mesenchymal stem cells: a case report. Frontiers in transplantation. vol 2. 2024-07-12. PMID:38993875. |
spinal cord injury (sci) is a debilitating disease with clinical manifestations ranging from incomplete neurological deficits affecting sensory and motor functions to complete paralysis. |
2024-07-12 |
2024-07-14 |
Not clear |
| Venkataramanan Srinivasan, Victoria Homer, Darren Barton, Abigail Clutterbuck-James, Siân Jenkins, Claire Potter, Kristian Brock, Ann Logan, Donna Smith, Lars Bruce, Zsuzsanna Nagy, Simon P Bac. A low molecular weight dextran sulphate, ILB®, for the treatment of amyotrophic lateral sclerosis (ALS): An open-label, single-arm, single-centre, phase II trial. PloS one. vol 19. issue 7. 2024-07-11. PMID:38990927. |
it is a fatal disease with specific loss of motor neurons in the spinal cord, brain stem, and motor cortex leading to progressive paralysis and usually death within five years of diagnosis. |
2024-07-11 |
2024-07-14 |
Not clear |
| Ermanna Turano, Federica Virla, Ilaria Scambi, Sylwia Dabrowska, Oluwamolakun Bankole, Raffaella Mariott. Adipose mesenchymal stem cells-derived extracellular vesicles exert their preferential action in damaged central sites of SOD1 mice rather than peripherally. European journal of histochemistry : EJH. vol 68. issue 3. 2024-07-04. PMID:38963135. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disorder involving motor neuron (mn) loss in the motor cortex, brainstem and spinal cord leading to progressive paralysis and death. |
2024-07-04 |
2024-07-10 |
mouse |
| D Leonardo Garcia-Ramirez, Jenna R McGrath, Ngoc T Ha, Jaimena H Wheel, Sebastian J Atoche, Lihua Yao, Nicholas J Stachowski, Simon F Giszter, Kimberly J Doughert. Covert actions of epidural stimulation on spinal locomotor circuits. bioRxiv : the preprint server for biology. 2024-07-01. PMID:38948733. |
spinal cord injury (sci) disrupts descending controls of the spinal cord, producing paralysis. |
2024-07-01 |
2024-07-03 |
mouse |
| Evaristus C Mbanefo, Allison Seifert, Manoj Kumar Yadav, Cheng-Rong Yu, Vijayaraj Nagarajan, Ashutosh Parihar, Sunanda Singh, Charles E Egwuag. A Camelid-Derived STAT-Specific Nanobody Inhibits Neuroinflammation and Ameliorates Experimental Autoimmune Encephalomyelitis (EAE). Cells. vol 13. issue 12. 2024-06-26. PMID:38920670. |
proinflammatory t-lymphocytes recruited into the brain and spinal cord mediate multiple sclerosis (ms) and currently there is no cure for ms. ifn-γ-producing th1 cells induce ascending paralysis in the spinal cord while il-17-producing th17 cells mediate cerebellar ataxia. |
2024-06-26 |
2024-06-29 |
mouse |
| Junming Fan, Xiaotong Du, Mengfan Chen, Yun Xu, Jinyu Xu, Leilei Lu, Shaoyan Zhou, Xiaoxia Kong, Ke Xu, Hongyu Zhan. Critical role of checkpoint kinase 1 in spinal cord injury-induced motor dysfunction in mice. International immunopharmacology. vol 138. 2024-06-25. PMID:38917519. |
spinal cord injury (sci) is a devastating neurotraumatic condition characterized by severe motor dysfunction and paralysis. |
2024-06-25 |
2024-06-29 |
mouse |
| Heng Zhou, Ziwei Li, Shuili Jing, Ben Wang, Zhifei Ye, Wei Xiong, Yonghao Liu, Ye Liu, Chun Xu, Tushar Kumeria, Yan He, Qingsong Y. Repair spinal cord injury with a versatile anti-oxidant and neural regenerative nanoplatform. Journal of nanobiotechnology. vol 22. issue 1. 2024-06-21. PMID:38902789. |
spinal cord injury (sci) often results in motor and sensory deficits, or even paralysis. |
2024-06-21 |
2024-06-23 |
Not clear |
| Marvin Man Ting Chung, Gabriel Ching Ngai Leung, Wing Yuk I. Surgical Reconstruction of Elbow Extension in Spinal Cord Injury and Tetraplegia: A Systematic Review. Journal of hand surgery global online. vol 6. issue 2. 2024-06-21. PMID:38903844. |
surgical reconstruction of elbow extension can help restore function in patients with tetraplegia and triceps paralysis because of spinal cord injury. |
2024-06-21 |
2024-06-23 |
Not clear |
| Sylwia Dabrowska, Ermanna Turano, Ilaria Scambi, Federica Virla, Alice Nodari, Francesco Pezzini, Mirco Galiè, Bruno Bonetti, Raffaella Mariott. A Cellular Model of Amyotrophic Lateral Sclerosis to Study the Therapeutic Effects of Extracellular Vesicles from Adipose Mesenchymal Stem Cells on Microglial Activation. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38891895. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by the progressive degeneration of upper and lower motor neurons (mns) in the brain and spinal cord, leading to progressive paralysis and death. |
2024-06-19 |
2024-06-21 |
human |
| Federico Fabris, Aram Megighian, Ornella Rossetto, Morena Simonato, Giampietro Schiavo, Marco Pirazzini, Cesare Montecucc. Local tetanus begins with a VAMP cleavage-associated neuromuscular junction paralysis around the site of tetanus neurotoxin release. The American journal of pathology. 2024-06-17. PMID:38885925. |
this paralysis follows the retrograde transport of tent inside the axons of spinal cord motoneurons and its uptake by inhibitory interneurons with cleavage of vamp, a synaptic vesicle protein required for neurotransmitter release. |
2024-06-17 |
2024-06-21 |
mouse |
| J Smith Leser, Joshua L Frost, Courtney J Wilson, Michael J Rudy, Penny Clarke, Kenneth L Tyle. VP1 is the primary determinant of neuropathogenesis in a mouse model of enterovirus D68 acute flaccid myelitis. Journal of virology. 2024-06-13. PMID:38869283. |
intramuscular (im) injection of neonatal swiss webster (sw) mice with us/il/14-18952 (il52), a clinical isolate from the 2014 ev-d68 epidemic, results in many of the pathogenic features of human afm, including viral infection of the spinal cord, death of motor neurons, and resultant progressive paralysis. |
2024-06-13 |
2024-06-15 |
mouse |
| J Smith Leser, Joshua L Frost, Courtney J Wilson, Michael J Rudy, Penny Clarke, Kenneth L Tyle. VP1 is the primary determinant of neuropathogenesis in a mouse model of enterovirus D68 acute flaccid myelitis. Journal of virology. 2024-06-13. PMID:38869283. |
in distinction, ca/14-4231 (ca4231), another clinical isolate from the 2014 ev-d68 outbreak, does not cause paralysis in mice, does not grow in the spinal cord, and does not cause motor neuron loss following im injection. |
2024-06-13 |
2024-06-15 |
mouse |
| Chenyu Wu, Yu Chen, Ximiao Chen, Yekai Zhang, Xiaoying Zhao, Yuxin Deng, Chenchao Li, Di Zhang, Xiaolei Zhang, Sheng Wan. 20-Deoxyingenol Activates Mitophagy Through TFEB and Promotes Functional Recovery After Spinal Cord Injury. Molecular neurobiology. 2024-06-12. PMID:38865079. |
spinal cord injury (sci) can lead to permanent paralysis and various motor, sensory and autonomic nervous system dysfunction. |
2024-06-12 |
2024-06-14 |
rat |
| Baoyang Hu, Yue Zhao, Chao Chen, Bin Wu, Hongbin Zhang, Bin Liu, Runquan Zheng, Fang Fan. Research hotspots and trends of microRNAs in spinal cord injury: a comprehensive bibliometric analysis. Frontiers in neurology. vol 15. 2024-06-05. PMID:38836004. |
spinal cord injury (sci) is a nervous system disease leading to motor and sensory dysfunction below the injury level, and can result in paralysis. |
2024-06-05 |
2024-06-07 |
Not clear |
| Hiroki Okayasu, Tetsuo Hayashi, Kazuya Yokota, Osamu Kawano, Hiroaki Sakai, Yuichiro Morishita, Muneaki Masuda, Kensuke Kubota, Hiroshi Ito, Takeshi Maed. Temporal dynamics of gait function in acute cervical spinal cord injury. BMC musculoskeletal disorders. vol 25. issue 1. 2024-06-04. PMID:38831297. |
following spinal cord injury (sci), gait function reaches a post-recovery plateau that depends on the paralysis severity. |
2024-06-04 |
2024-06-06 |
Not clear |
| Yanzhi Wan, Keqin Tan, Hong Zh. QL1604 combined with bevacizumab as an innovative first-line treatment for HCC patient with extensive metastasis who showed remarkable effect: a case report. Frontiers in pharmacology. vol 15. 2024-06-04. PMID:38831888. |
as the tumor invaded the spinal canal and pressed on the spinal cord, the patient experienced paralysis in the lower limbs. |
2024-06-04 |
2024-06-06 |
Not clear |
| Haimei Yang, Chaolun Liang, Junhua Luo, Xiuzhen Liu, Wanshun Wang, Kunrui Zheng, Dan Luo, Yu Hou, Da Guo, Dingkun Lin, Xiasheng Zheng, Xing L. Transplantation of Wnt5a-modified Bone Marrow Mesenchymal Stem Cells Promotes Recovery After Spinal Cord Injury via the PI3K/AKT Pathway. Molecular neurobiology. 2024-05-25. PMID:38795301. |
spinal cord injury (sci) is a severe neurological condition that can lead to paralysis or even death. |
2024-05-25 |
2024-05-27 |
rat |
| Shurui Chen, Jinpeng Gao, Sen Lin, Haosen Zha. Enhancing anti-neuroinflammation effect of X-ray-triggered RuFe-based metal-organic framework with dual enzyme-like activities. Frontiers in bioengineering and biotechnology. vol 12. 2024-05-06. PMID:38707498. |
traumatic spinal cord injury (sci), often resulting from external physical trauma, initiates a series of complex pathophysiological cascades, with severe cases leading to paralysis and presenting significant clinical challenges. |
2024-05-06 |
2024-05-08 |
Not clear |
| Haruki Mori, Gosuke Satoh, Hideki Takashima, Takashi Masuda, Tomoo Man. Combined rehabilitation therapy with botulinum toxin to the upper limbs for acute spinal cord injury: A case report. Spinal cord series and cases. vol 10. issue 1. 2024-05-04. PMID:38704389. |
patients with spinal cord injury (sci) and incomplete paralysis may experience muscle immobilization due to functional impairment of agonist and antagonist muscles. |
2024-05-04 |
2024-05-07 |
Not clear |
| Xinliang Yue, Xing Yu, Fengxian Wang, Dingyan Zhao, Yukun Ma, He Zha. Spinal cord injury without radiographic abnormality with diffuse idiopathic skeletal hyperostosis: A case report. International journal of surgery case reports. vol 119. 2024-04-28. PMID:38678990. |
spinal cord injury without fracture dislocation (sciwora) is relatively rare, and spastic paralysis for more than 2 months with diffuse diopathic skeletal hyperoseosis (dish) is even rarer. |
2024-04-28 |
2024-05-01 |
Not clear |