| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alan S Verkman, Julien Ratelade, Andrea Rossi, Hua Zhang, Lukmanee Tradtranti. Aquaporin-4: orthogonal array assembly, CNS functions, and role in neuromyelitis optica. Acta pharmacologica Sinica. vol 32. issue 6. 2011-09-30. PMID:21552296. |
aqp4 is also involved in the neuroinflammatory demyelinating disease neuromyelitis optica (nmo), where autoantibodies (nmo-igg) targeting aqp4 produce astrocyte damage and inflammation. |
2011-09-30 |
2023-08-12 |
mouse |
| Russell C Dale, Esther Tantsis, Vera Merheb, Fabienne Brilo. Cerebrospinal fluid B-cell expansion in longitudinally extensive transverse myelitis associated with neuromyelitis optica immunoglobulin G. Developmental medicine and child neurology. vol 53. issue 9. 2011-09-30. PMID:21679355. |
cerebrospinal fluid b-cell expansion in longitudinally extensive transverse myelitis associated with neuromyelitis optica immunoglobulin g. a first episode of central nervous system (cns) demyelination may represent heterogeneous entities such as acute disseminated encephalomyelitis, clinically isolated syndrome, neuromyelitis optica (nmo), or multiple sclerosis. |
2011-09-30 |
2023-08-12 |
Not clear |
| Joaquín A Peña, María Elena Ravelo, Eduardo Mora-La Cruz, Cecilia Montiel-Nav. NMO in pediatric patients: brain involvement and clinical expression. Arquivos de neuro-psiquiatria. vol 69. issue 1. 2011-09-21. PMID:21359420. |
to analyze the clinical, neuroimaging characteristics and positivity of the acquaporin water channel (nmo-igg) in pediatric patients with neuromyelitis optica (nmo). |
2011-09-21 |
2023-08-12 |
Not clear |
| b' Egemen Idiman, Serkan Ozakba\\xc5\\x9. The limited demyelinating diseases: the voyage of optic neuritis and transverse myelitis to multiple sclerosis and neuromyelitis. Expert review of neurotherapeutics. vol 11. issue 3. 2011-09-20. PMID:21375450.' |
neuromyelitis optica (nmo) and the nmo spectrum disorders have a predilection for the optic nerves and spinal cord. |
2011-09-20 |
2023-08-12 |
Not clear |
| Kai-Chen Wang, Chao-Lin Lee, Shao-Yuan Chen, Kuan-Hsiang Lin, Ching-Piao Tsa. Glatiramer acetate could be a hypothetical therapeutic agent for neuromyelitis optica. Medical hypotheses. vol 76. issue 6. 2011-09-15. PMID:21398045. |
neuromyelitis optica (nmo) is characterized by concurrence of optic neuritis and transverse myelitis, which is typically associated with a spinal cord lesion extending three or more vertebral segments. |
2011-09-15 |
2023-08-12 |
mouse |
| Jonathan M Crane, Andrea Rossi, Tripta Gupta, Jeffrey L Bennett, A S Verkma. Orthogonal array formation by human aquaporin-4: examination of neuromyelitis optica-associated aquaporin-4 polymorphisms. Journal of neuroimmunology. vol 236. issue 1-2. 2011-09-13. PMID:21621278. |
pathogenic autoantibodies target aquaporin-4 (aqp4) water channels in individuals with neuromyelitis optica (nmo). |
2011-09-13 |
2023-08-12 |
human |
| Xiaoli Yu, Miyoko Green, Don Gilden, Chiwah Lam, Katherine Bautista, Jeffrey L Bennet. Identification of peptide targets in neuromyelitis optica. Journal of neuroimmunology. vol 236. issue 1-2. 2011-09-13. PMID:21621279. |
neuromyelitis optica (nmo) is an inflammatory demyelinating disease that predominantly affects the optic nerves and spinal cord. |
2011-09-13 |
2023-08-12 |
Not clear |
| Takafumi Hosokawa, Hideto Nakajima, Yoshimitsu Doi, Masakazu Sugino, Fumiharu Kimura, Toshiaki Hanafusa, Toshiyuki Takahash. Increased serum matrix metalloproteinase-9 in neuromyelitis optica: implication of disruption of blood-brain barrier. Journal of neuroimmunology. vol 236. issue 1-2. 2011-09-13. PMID:21621856. |
to investigate the pathogenicity of mmp-9 in neuromyelitis optica (nmo), serum and csf mmp-9 concentrations were measured in 13 nmo and 15 multiple sclerosis (ms) patients and 14 healthy controls, and correlated with clinical and laboratorial parameters. |
2011-09-13 |
2023-08-12 |
Not clear |
| Akiyuki Uzawa, Masahiro Mori, Saeko Masuda, Satoshi Kuwabar. Markedly elevated soluble intercellular adhesion molecule 1, soluble vascular cell adhesion molecule 1 levels, and blood-brain barrier breakdown in neuromyelitis optica. Archives of neurology. vol 68. issue 7. 2011-09-09. PMID:21747031. |
to evaluate the degree of blood-brain barrier disruption in patients with neuromyelitis optica (nmo) and to clarify whether the levels of soluble intercellular adhesion molecule 1 (sicam-1) and soluble vascular cell adhesion molecule 1 (svcam-1) in patients with nmo can be useful biomarkers for blood-brain barrier breakdown. |
2011-09-09 |
2023-08-12 |
Not clear |
| Nicolas Collongues, Philippe Cabre, Romain Marignier, Hèléne Zéphir, Caroline Papeix, Bertrand Audoin, Christine Lebrun-Frenay, Jean Pelletier, Bertrand Fontaine, Patrick Vermersch, Christian Confavreux, Jérôme de Sez. A benign form of neuromyelitis optica: does it exist? Archives of neurology. vol 68. issue 7. 2011-09-09. PMID:21747032. |
few data exist on a possible benign form of neuromyelitis optica (nmo). |
2011-09-09 |
2023-08-12 |
Not clear |
| Ken Ikeda, Hirono Ito, Takanobu Hidaka, Takanori Takazawa, Tokinori Sekine, Yasuhiro Yoshii, Takehisa Hirayama, Kiyokazu Kawabe, Osamu Kano, Yasuo Iwasak. Repeated non-enhancing tumefactive lesions in a patient with a neuromyelitis optica spectrum disorder. Internal medicine (Tokyo, Japan). vol 50. issue 9. 2011-08-30. PMID:21532234. |
neuromyelitis optica (nmo)-igg was seropositive. |
2011-08-30 |
2023-08-12 |
Not clear |
| Robert C Axtell, Chander Raman, Lawrence Steinma. Interferon-β exacerbates Th17-mediated inflammatory disease. Trends in immunology. vol 32. issue 6. 2011-08-22. PMID:21530402. |
in some cases, ifn-β exacerbates ms, and it consistently worsens neuromyelitis optica (nmo). |
2011-08-22 |
2023-08-12 |
human |
| Chihiro Fujii, Takahiko Tokuda, Noriko Ishigami, Toshiki Mizuno, Masanori Nakagaw. Usefulness of serum S100B as a marker for the acute phase of aquaporin-4 autoimmune syndrome. Neuroscience letters. vol 494. issue 1. 2011-08-15. PMID:21371524. |
the aquaporin-4 (aqp4) water channel antibody is used in the diagnosis of neuromyelitis optica (nmo) due to its high sensitivity and high specificity. |
2011-08-15 |
2023-08-12 |
Not clear |
| Samira Saadoun, Patrick Waters, Claire Macdonald, Leslie R Bridges, B Anthony Bell, Angela Vincent, A S Verkman, Marios C Papadopoulo. T cell deficiency does not reduce lesions in mice produced by intracerebral injection of NMO-IgG and complement. Journal of neuroimmunology. vol 235. issue 1-2. 2011-08-08. PMID:21492943. |
we reported recently that intracerebral administration of nmo-igg with human complement produces neuromyelitis optica (nmo) lesions in mice. |
2011-08-08 |
2023-08-12 |
mouse |
| Masami Tanaka, Hiroshi Uchizumi, Keiko Tanak. [Evaluation of blood flow and the cross-sectional area of internal jugular vein in Japanese multiple sclerosis and neuromyelitis optica patients]. Rinsho shinkeigaku = Clinical neurology. vol 51. issue 6. 2011-08-05. PMID:21735737. |
we examined the blood flow and the cross-sectional area of the internal jugular veins using doppler ultrasound (vivid 7 pro, ge health japan, tokyo) in 17 ms (8 males and 9 females; 20-58 years of age, median 38 years) and 11 neuromyelitis optica (nmo) japanese patients (1 male and 10 females; 23-60 years of age, median 44 years). |
2011-08-05 |
2023-08-12 |
Not clear |
| Sudhakar Reddy Kalluri, Veit Rothhammer, Ori Staszewski, Rajneesh Srivastava, Franziska Petermann, Marco Prinz, Bernhard Hemmer, Thomas Kor. Functional characterization of aquaporin-4 specific T cells: towards a model for neuromyelitis optica. PloS one. vol 6. issue 1. 2011-08-02. PMID:21264240. |
antibodies to the water channel protein aquaporin-4 (aqp4), which is expressed in astrocytic endfeet at the blood brain barrier, have been identified in the serum of neuromyelitis optica (nmo) patients and are believed to induce damage to astrocytes. |
2011-08-02 |
2023-08-12 |
Not clear |
| E I Kampylafka, J G Routsias, H Alexopoulos, M C Dalakas, H M Moutsopoulos, A G Tzioufa. Fine specificity of antibodies against AQP4: epitope mapping reveals intracellular epitopes. Journal of autoimmunity. vol 36. issue 3-4. 2011-08-01. PMID:21333492. |
the autoantibody to aquaporin-4 (aqp4) is a marker and a pathogenetic factor in neuromyelitis optica (nmo) (devic's syndrome). |
2011-08-01 |
2023-08-12 |
human |
| Xiao-fan You, Jing Ye, Cun-jiang Li, Zhang-yuan Liao, Hui Su. [Neuromyelitis optica IgG and related clinical features of patients with neuromyelitis optica]. Zhonghua yi xue za zhi. vol 90. issue 35. 2011-07-28. PMID:21092475. |
to investigate the differential diagnostic value of nmo-igg for neuromyelitis optica (nmo) versus multiple sclerosis (ms) and to analyze its possible clinical features related to nmo-igg. |
2011-07-28 |
2023-08-12 |
Not clear |
| N Asgari, S T Lillevang, H P B Skejoe, M Falah, E Stenager, K O Kyvi. A population-based study of neuromyelitis optica in Caucasians. Neurology. vol 76. issue 18. 2011-07-25. PMID:21536639. |
epidemiologic studies have suggested different prevalence of neuromyelitis optica (nmo) in different ethnic groups. |
2011-07-25 |
2023-08-12 |
Not clear |
| Sandrine Brunot, Sandra Vukusic, Agnès Fromont, Grégory Couvreur, Christiane Mousson, Maurice Giroud, Christian Confavreux, Thibault Morea. [Plasma exchanges in severe and acute inflammatory demyelinating attacks of the central nervous system]. Presse medicale (Paris, France : 1983). vol 40. issue 5. 2011-07-19. PMID:21353760. |
these diseases are explosive or pseudotumoral multiple sclerosis (ms), acute disseminated encephalomyelitis (adem), transverse myelitis and neuromyelitis optica (nmo). |
2011-07-19 |
2023-08-12 |
Not clear |