| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maureen A Mealy, Dean M Wingerchuk, Benjamin M Greenberg, Michael Lev. Epidemiology of neuromyelitis optica in the United States: a multicenter analysis. Archives of neurology. vol 69. issue 9. 2012-12-12. PMID:22733096. |
neuromyelitis optica (nmo) and nmo spectrum disorders (nmosds) are uncommon neuroinflammatory syndromes that are distinct from multiple sclerosis and associated with nmo-igg, a serologic antibody against aquaporin 4. |
2012-12-12 |
2023-08-12 |
Not clear |
| Honghao Wang, Kai Wang, Xiaonan Zhong, Yongqiang Dai, Wei Qiu, Aimin Wu, Xueqiang H. Notable increased cerebrospinal fluid levels of soluble interleukin-6 receptors in neuromyelitis optica. Neuroimmunomodulation. vol 19. issue 5. 2012-12-12. PMID:22777162. |
cerebrospinal fluid (csf) il-6 has shown to be increased in neuromyelitis optica (nmo). |
2012-12-12 |
2023-08-12 |
Not clear |
| Yan Xu, Yao Zhang, Jing Ye, Bin Peng, Jian-Ming Wang, Li-Ying Cu. Successful treatment of a woman with relapsing neuromyelitis optica by interferon beta. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 33. issue 4. 2012-12-07. PMID:22120187. |
neuromyelitis optica (nmo) is an antibody-mediated disease with the target antigen being the water channel aquaporin-4 (aqp4). |
2012-12-07 |
2023-08-12 |
Not clear |
| Yoon-Joo Kim, Seung-Won Jung, Yonggoo Kim, Yeon-Joon Park, Kyungja Han, Eun-Jee O. Detection of anti-aquaporin-4 antibodies in neuromyelitis optica: comparison of tissue-based and cell-based indirect immunofluorescence assays and ELISA. Journal of clinical laboratory analysis. vol 26. issue 3. 2012-12-07. PMID:22628234. |
nmo-igg against aquaporin-4 (aqp4) is a specific marker for neuromyelitis optica (nmo). |
2012-12-07 |
2023-08-12 |
mouse |
| Joanna Kitley, Mark Woodhall, Patrick Waters, M Isabel Leite, Emma Devenney, John Craig, Jacqueline Palace, Angela Vincen. Myelin-oligodendrocyte glycoprotein antibodies in adults with a neuromyelitis optica phenotype. Neurology. vol 79. issue 12. 2012-12-04. PMID:22914827. |
to report an association of myelin-oligodendrocyte glycoprotein (mog) antibodies with aquaporin-4 (aqp4) antibody-seronegative neuromyelitis optica (nmo) and neuromyelitis optica spectrum disorder (nmosd) in adults. |
2012-12-04 |
2023-08-12 |
Not clear |
| Douglas Sato, Dagoberto Callegaro, Marco Aurélio Lana-Peixoto, Kazuo Fujihar. Treatment of neuromyelitis optica: an evidence based review. Arquivos de neuro-psiquiatria. vol 70. issue 1. 2012-11-30. PMID:22218475. |
neuromyelitis optica (nmo) is an inflammatory disease of the central nervous system characterized by severe optic neuritis and transverse myelitis, usually with a relapsing course. |
2012-11-30 |
2023-08-12 |
Not clear |
| Julien Ratelade, A S Verkma. Neuromyelitis optica: aquaporin-4 based pathogenesis mechanisms and new therapies. The international journal of biochemistry & cell biology. vol 44. issue 9. 2012-11-29. PMID:22713791. |
neuromyelitis optica (nmo) is an autoimmune 'aquaporinopathy' of the central nervous system that causes inflammatory demyelinating lesions primarily in spinal cord and optic nerve, leading to paralysis and blindness. |
2012-11-29 |
2023-08-12 |
Not clear |
| S Jarius, F Paul, D Franciotta, J de Seze, C Münch, M Salvetti, K Ruprecht, M Liebetrau, K P Wandinger, G Akman-Demir, A Melms, W Kristoferitsch, B Wildeman. Neuromyelitis optica spectrum disorders in patients with myasthenia gravis: ten new aquaporin-4 antibody positive cases and a review of the literature. Multiple sclerosis (Houndmills, Basingstoke, England). vol 18. issue 8. 2012-11-27. PMID:22183934. |
neuromyelitis optica (nmo, devic syndrome) and myasthenia gravis (mg) are rare antibody-mediated autoimmune disorders. |
2012-11-27 |
2023-08-12 |
Not clear |
| Marina Papais Alvarenga, Regina Maria Papais Alvarenga, Marcos Papais Alvarenga, Adriano Miranda Santos, Luiz Claudio Santos Thule. Anti-AQP(4) antibody in idiopathic acute transverse myelitis with recurrent clinical course: frequency of positivity and influence in prognosis. The journal of spinal cord medicine. vol 35. issue 4. 2012-11-27. PMID:22925751. |
the anti-aquaporin4 (anti-aqp4) antibody is specific for neuromyelitis optica (nmo), but is also found in limited forms. |
2012-11-27 |
2023-08-12 |
Not clear |
| S Jarius, B Wildeman. The case of the Marquis de Causan (1804): an early account of visual loss associated with spinal cord inflammation. Journal of neurology. vol 259. issue 7. 2012-11-26. PMID:22237820. |
the recent discovery of disease specific and pathogenic autoantibodies in neuromyelitis optica (nmo, devic's disease) has revived the interest in this intriguing yet often devastating condition. |
2012-11-26 |
2023-08-12 |
Not clear |
| T F Runia, E D van Pelt-Gravesteijn, R Q Hintze. Recent gains in clinical multiple sclerosis research. CNS & neurological disorders drug targets. vol 11. issue 5. 2012-11-19. PMID:22583434. |
clinics of childhood-onset ms versus adult-onset are explained, as are diagnostics, differential diagnoses and therapeutic options for children with ms. also another demyelinating disease of the cns, neuromyelitis optica (nmo) is highlighted. |
2012-11-19 |
2023-08-12 |
Not clear |
| Shaista A Siddiqi, Mubashira Hashmi, Zeeshan Azmat, Shahid Mustafa, Khurram A Siddiqu. Pulmonary tuberculosis with neuromyelitis optica: an uncommon association of a common disease. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP. vol 22. issue 8. 2012-11-13. PMID:22868021. |
neuromyelitis optica (nmo) is a well known neurological entity which has been described in association with several systemic disorders like systemic lupus erythematosis, diabetes mellitus, hypothyroidism, exposure to insecticides etc. |
2012-11-13 |
2023-08-12 |
Not clear |
| Yaou Liu, Yunyun Duan, Yong He, Chunshui Yu, Jun Wang, Jing Huang, Jing Ye, Helmut Butzkueven, Kuncheng Li, Ni Sh. A tract-based diffusion study of cerebral white matter in neuromyelitis optica reveals widespread pathological alterations. Multiple sclerosis (Houndmills, Basingstoke, England). vol 18. issue 7. 2012-11-12. PMID:22183932. |
it remains uncertain whether neuromyelitis optica (nmo) exhibits diffuse cerebral abnormalities or whether the pathology is truly restricted to optic nerves and spinal cord in the majority of cases. |
2012-11-12 |
2023-08-12 |
Not clear |
| Benjamin M Greenberg, Donna Graves, Gina Remington, Paula Hardeman, Martha Mann, Nitin Karandikar, Olaf Stuve, Nancy Monson, Elliot Frohma. Rituximab dosing and monitoring strategies in neuromyelitis optica patients: creating strategies for therapeutic success. Multiple sclerosis (Houndmills, Basingstoke, England). vol 18. issue 7. 2012-11-12. PMID:22261118. |
neuromyelitis optica (nmo) is an autoimmune condition that predominantly causes severe optic neuritis and transverse myelitis. |
2012-11-12 |
2023-08-12 |
Not clear |
| Danilo B Fernandes, Renata de Iracema P Ramos, Carolina Falcochio, Samira Apóstolos-Pereira, Dagoberto Callegaro, Mário Luiz Ribeiro Monteir. Comparison of visual acuity and automated perimetry findings in patients with neuromyelitis optica or multiple sclerosis after single or multiple attacks of optic neuritis. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. vol 32. issue 2. 2012-11-06. PMID:22157535. |
to review the clinical characteristics of patients with neuromyelitis optica (nmo) and to compare their visual outcome with those of patients with optic neuritis (on) and multiple sclerosis (ms). |
2012-11-06 |
2023-08-12 |
Not clear |
| Takeshi Kezuka, Yoshihiko Usui, Naoyuki Yamakawa, Yoshimichi Matsunaga, Ryusaku Matsuda, Masayuki Masuda, Hiroya Utsumi, Keiko Tanaka, Hiroshi Got. Relationship between NMO-antibody and anti-MOG antibody in optic neuritis. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. vol 32. issue 2. 2012-11-06. PMID:22157536. |
damage to astrocytes by anti-aquaporin-4 antibody (aqp4-ab), also known as nmo antibody, has been implicated as the cause of neuromyelitis optica. |
2012-11-06 |
2023-08-12 |
Not clear |
| Mark J Morrow, Dean Wingerchu. Neuromyelitis optica. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. vol 32. issue 2. 2012-11-06. PMID:22617743. |
neuromyelitis optica (nmo) is a disabling inflammatory condition that targets astrocytes in the optic nerves and spinal cord. |
2012-11-06 |
2023-08-12 |
Not clear |
| Sung-Min Kim, Min Jin Go, Jung-Joon Sung, Kyung Seok Park, Kwang-Woo Le. Painful tonic spasm in neuromyelitis optica: incidence, diagnostic utility, and clinical characteristics. Archives of neurology. vol 69. issue 8. 2012-10-30. PMID:22473770. |
to evaluate the diagnostic utility and clinical characteristics of painful tonic spasm (pts) in neuromyelitis optica (nmo). |
2012-10-30 |
2023-08-12 |
Not clear |
| Michel Varrin-Doyer, Collin M Spencer, Ulf Schulze-Topphoff, Patricia A Nelson, Robert M Stroud, Bruce A C Cree, Scott S Zamvi. Aquaporin 4-specific T cells in neuromyelitis optica exhibit a Th17 bias and recognize Clostridium ABC transporter. Annals of neurology. vol 72. issue 1. 2012-10-24. PMID:22807325. |
aquaporin 4 (aqp4)-specific autoantibodies in neuromyelitis optica (nmo) are immunoglobulin (ig)g1, a t cell-dependent ig subclass, indicating that aqp4-specific t cells participate in nmo pathogenesis. |
2012-10-24 |
2023-08-12 |
Not clear |
| John W Prineas, John D E Parrat. Oligodendrocytes and the early multiple sclerosis lesion. Annals of neurology. vol 72. issue 1. 2012-10-24. PMID:22829266. |
one feature of ms that is not understood is the extraordinarily close resemblance the disease shows pathologically to neuromyelitis optica (nmo), including that demyelination in both is secondary to a loss of caspase 3-positive apoptotic oligodendrocytes. |
2012-10-24 |
2023-08-12 |
Not clear |