| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Raffaele Nardone, Giulio Zuccoli, Francesco Brigo, Eugen Trinka, Ryan T Fitzgeral. Seronegative neuromyelitis optica presenting with life-threatening respiratory failure. The journal of spinal cord medicine. vol 39. issue 6. 2018-01-12. PMID:26679536. |
dyspnea has rarely been reported as a presenting symptom in patients with neuromyelitis optica (nmo). |
2018-01-12 |
2023-08-13 |
Not clear |
| Romain Marignier, Alvaro Cobo Calvo, Sandra Vukusi. Neuromyelitis optica and neuromyelitis optica spectrum disorders. Current opinion in neurology. vol 30. issue 3. 2018-01-11. PMID:28306572. |
the discovery of highly specific auto-antibodies directed against the water channel aquaporin 4 was a quantum leap in the definition, classification and management of neuromyelitis optica (nmo). |
2018-01-11 |
2023-08-13 |
Not clear |
| Wenshu Qian, Koon Ho Chan, Edward S Hui, Chi Yan Lee, Yong Hu, Henry Ka-Fung Ma. Application of diffusional kurtosis imaging to detect occult brain damage in multiple sclerosis and neuromyelitis optica. NMR in biomedicine. vol 29. issue 11. 2018-01-02. PMID:27602543. |
multiple sclerosis (ms) and neuromyelitis optica (nmo) are two common types of inflammatory demyelinating disease of the central nervous system. |
2018-01-02 |
2023-08-13 |
human |
| Akiyuki Uzawa, Masahiro Mori, Hiroki Masuda, Ryohei Ohtani, Tomohiko Uchida, Setsu Sawai, Satoshi Kuwabar. Interleukin-6 analysis of 572 consecutive CSF samples from neurological disorders: A special focus on neuromyelitis optica. Clinica chimica acta; international journal of clinical chemistry. vol 469. 2018-01-01. PMID:28283439. |
our main objectives are to compare the csf il-6 levels among various neurological disorders and to evaluate the significance of csf il-6 measurements for the diagnosis of neuromyelitis optica (nmo). |
2018-01-01 |
2023-08-13 |
Not clear |
| Lan Chu, Qingqing Dai, Zhu Xu, Dian He, Hao Wang, Qingsong Wang, Yifan Zhang, Yingwu Zhu, Yuan Li, Gang Cai, Krantic Slavica, Kermode Alla. Association Between the Single Nucleotide Polymorphism and the Level of Aquaporin-4 Protein Expression in Han and Minority Chinese with Inflammatory Demyelinating Diseases of the Central Nervous System. Molecular neurobiology. vol 53. issue 5. 2017-12-22. PMID:25895050. |
polymorphisms of aqp4 exons 1-5 were determined by sequencing dna from 67 patients with central nervous system inflammatory demyelinating diseases, including neuromyelitis optica (nmo), multiple sclerosis, recurrent or simultaneous bilateral optic neuritis, and longitudinally extensive transverse myelitis. |
2017-12-22 |
2023-08-13 |
human |
| H Chen, W Qiu, Q Zhang, J Wang, Z Shi, J Liu, Z Lian, H Feng, X Miao, H Zho. Comparisons of the efficacy and tolerability of mycophenolate mofetil and azathioprine as treatments for neuromyelitis optica and neuromyelitis optica spectrum disorder. European journal of neurology. vol 24. issue 1. 2017-12-22. PMID:27783452. |
to research and compare the efficacy and tolerability of mycophenolate mofetil (mmf) and azathioprine (aza) in neuromyelitis optica (nmo) and nmo spectrum disorder (nmosd). |
2017-12-22 |
2023-08-13 |
Not clear |
| Xiaoming Yao, Alan S Verkma. Marked central nervous system pathology in CD59 knockout rats following passive transfer of Neuromyelitis optica immunoglobulin G. Acta neuropathologica communications. vol 5. issue 1. 2017-12-19. PMID:28212662. |
marked central nervous system pathology in cd59 knockout rats following passive transfer of neuromyelitis optica immunoglobulin g. neuromyelitis optica spectrum disorders (herein called nmo) is an inflammatory demyelinating disease of the central nervous system in which pathogenesis involves complement-dependent cytotoxicity (cdc) produced by immunoglobulin g autoantibodies targeting aquaporin-4 (aqp4-igg) on astrocytes. |
2017-12-19 |
2023-08-13 |
rat |
| Xiaoming Yao, Alan S Verkma. Complement regulator CD59 prevents peripheral organ injury in rats made seropositive for neuromyelitis optica immunoglobulin G. Acta neuropathologica communications. vol 5. issue 1. 2017-12-19. PMID:28750658. |
complement regulator cd59 prevents peripheral organ injury in rats made seropositive for neuromyelitis optica immunoglobulin g. pathogenesis in aquaporin-4 immunoglobulin g (aqp4-igg) seropositive neuromyelitis optica spectrum disorders (herein called nmo) involves complement-dependent cytotoxicity initiated by aqp4-igg binding to astrocyte aqp4. |
2017-12-19 |
2023-08-13 |
rat |
| Moli Fan, Ying Fu, Lei Su, Yi Shen, Kristofer Wood, Li Yang, Yaou Liu, Fu-Dong Sh. Comparison of brain and spinal cord magnetic resonance imaging features in neuromyelitis optica spectrum disorders patients with or without aquaporin-4 antibody. Multiple sclerosis and related disorders. vol 13. 2017-12-14. PMID:28427704. |
the spinal cord and brain measurements are rarely investigated in neuromyelitis optica (nmo) patients with and without antibodies to aquaporin-4 (aqp4), directly compared to multiple sclerosis (ms) patients. |
2017-12-14 |
2023-08-13 |
Not clear |
| Lukmanee Tradtrantip, Xiaoming Yao, Tao Su, Alex J Smith, Alan S Verkma. Bystander mechanism for complement-initiated early oligodendrocyte injury in neuromyelitis optica. Acta neuropathologica. vol 134. issue 1. 2017-12-11. PMID:28567523. |
neuromyelitis optica spectrum disorder (herein called nmo) is an autoimmune inflammatory disease of the central nervous system in which immunoglobulin g antibodies against astrocyte water channel aquaporin-4 (aqp4-igg) cause demyelination and neurological deficit. |
2017-12-11 |
2023-08-13 |
rat |
| Marie-Theres Weil, Wiebke Möbius, Anne Winkler, Torben Ruhwedel, Claudia Wrzos, Elisa Romanelli, Jeffrey L Bennett, Lukas Enz, Norbert Goebels, Klaus-Armin Nave, Martin Kerschensteiner, Nicole Schaeren-Wiemers, Christine Stadelmann, Mikael Simon. Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases. Cell reports. vol 16. issue 2. 2017-12-01. PMID:27346352. |
we employed autoantibody-mediated animal models of demyelinating diseases, including a rat model of neuromyelitis optica (nmo), to target myelin and found that myelin lamellae are broken down into vesicular structures at the innermost region of the myelin sheath. |
2017-12-01 |
2023-08-13 |
rat |
| Yiting Liu, Katherine S Given, Danielle E Harlow, Adeline M Matschulat, Wendy B Macklin, Jeffrey L Bennett, Gregory P Owen. Myelin-specific multiple sclerosis antibodies cause complement-dependent oligodendrocyte loss and demyelination. Acta neuropathologica communications. vol 5. issue 1. 2017-10-25. PMID:28340598. |
demyelination, glial and neuronal viability, and complement pathway activation were assayed by immunofluorescence microscopy and compared to the effects of an aquaporin-4 water channel (aqp4)-specific rab derived from a neuromyelitis optica (nmo) patient. |
2017-10-25 |
2023-08-13 |
mouse |
| Teresa M Crout, Laura P Parks, Vikas Majithi. Neuromyelitis Optica (Devic's Syndrome): an Appraisal. Current rheumatology reports. vol 18. issue 8. 2017-10-24. PMID:27402111. |
neuromyelitis optica (nmo) and neuromyelitis optica spectrum disorders (nmosd), previously known as devic's syndrome, are a group of inflammatory disorders of the central nervous system (cns) characterized by severe, immune-mediated demyelination and axonal damage, predominantly targeting optic nerves and the spinal cord typically associated with a disease-specific serum nmo-igg antibody that selectively binds aquaporin-4 (aqp4). |
2017-10-24 |
2023-08-13 |
Not clear |
| Domenico Alberga, Daniela Trisciuzzi, Gianluca Lattanzi, Jeffrey L Bennett, Alan S Verkman, Giuseppe Felice Mangiatordi, Orazio Nicolott. Comparative molecular dynamics study of neuromyelitis optica-immunoglobulin G binding to aquaporin-4 extracellular domains. Biochimica et biophysica acta. Biomembranes. vol 1859. issue 8. 2017-10-23. PMID:28477975. |
neuromyelitis optica (nmo) is an inflammatory demyelinating disease of the central nervous system in which most patients have serum autoantibodies (called nmo-igg) that bind to astrocyte water channel aquaporin-4 (aqp4). |
2017-10-23 |
2023-08-13 |
Not clear |
| Elisa Schneider, Hanna Zimmermann, Timm Oberwahrenbrock, Falko Kaufhold, Ella Maria Kadas, Axel Petzold, Frieder Bilger, Nadja Borisow, Sven Jarius, Brigitte Wildemann, Klemens Ruprecht, Alexander U Brandt, Friedemann Pau. Optical Coherence Tomography Reveals Distinct Patterns of Retinal Damage in Neuromyelitis Optica and Multiple Sclerosis. PloS one. vol 8. issue 6. 2017-10-20. PMID:23805202. |
neuromyelitis optica (nmo) and relapsing-remitting multiple sclerosis (rrms) are difficult to differentiate solely on clinical grounds. |
2017-10-20 |
2023-08-12 |
Not clear |
| Carlos A Sánchez-Catasús, José Cabrera-Gomez, William Almaguer Melián, José Luis Giroud Benítez, Rafael Rodríguez Rojas, Jorge Bosch Bayard, Lídice Galán, Reinaldo Galvizu Sánchez, Nancy Pavón Fuentes, Pedro Valdes-Sos. Brain Tissue Volumes and Perfusion Change with the Number of Optic Neuritis Attacks in Relapsing Neuromyelitis Optica: A Voxel-Based Correlation Study. PloS one. vol 8. issue 6. 2017-10-13. PMID:23824339. |
recent neuroimaging studies show that brain abnormalities in neuromyelitis optica (nmo) are more frequent than earlier described. |
2017-10-13 |
2023-08-12 |
Not clear |
| R Marignier, A Ruiz, S Cavagna, A Nicole, C Watrin, M Touret, S Parrot, G Malleret, C Peyron, C Benetollo, N Auvergnon, S Vukusic, P Giraudo. Neuromyelitis optica study model based on chronic infusion of autoantibodies in rat cerebrospinal fluid. Journal of neuroinflammation. vol 13. issue 1. 2017-10-10. PMID:27193196. |
devic's neuromyelitis optica (nmo) is an autoimmune astrocytopathy, associated with central nervous system inflammation, demyelination, and neuronal injury. |
2017-10-10 |
2023-08-13 |
rat |
| Adi Vaknin-Dembinsky, Hanna Charbit, Livnat Brill, Oded Abramsky, Devorah Gur-Wahnon, Iddo Z Ben-Dov, Iris Lavo. Circulating microRNAs as biomarkers for rituximab therapy, in neuromyelitis optica (NMO). Journal of neuroinflammation. vol 13. issue 1. 2017-10-10. PMID:27393339. |
circulating micrornas as biomarkers for rituximab therapy, in neuromyelitis optica (nmo). |
2017-10-10 |
2023-08-13 |
Not clear |
| Adi Vaknin-Dembinsky, Hanna Charbit, Livnat Brill, Oded Abramsky, Devorah Gur-Wahnon, Iddo Z Ben-Dov, Iris Lavo. Circulating microRNAs as biomarkers for rituximab therapy, in neuromyelitis optica (NMO). Journal of neuroinflammation. vol 13. issue 1. 2017-10-10. PMID:27393339. |
neuromyelitis optica (nmo) is a chronic autoimmune disease of the central nervous system (cns). |
2017-10-10 |
2023-08-13 |
Not clear |
| Yiting Liu, Danielle E Harlow, Katherine S Given, Gregory P Owens, Wendy B Macklin, Jeffrey L Bennet. Variable sensitivity to complement-dependent cytotoxicity in murine models of neuromyelitis optica. Journal of neuroinflammation. vol 13. issue 1. 2017-10-10. PMID:27905992. |
studies of neuromyelitis optica (nmo), an autoimmune disease of the central nervous system (cns), have demonstrated that autoantibodies against the water channel aquaporin-4 (aqp4) induce astrocyte damage through complement-dependent cytotoxicity (cdc). |
2017-10-10 |
2023-08-13 |
mouse |