| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kenji Rowel Q Lim, Chantal Yoon, Toshifumi Yokot. Applications of CRISPR/Cas9 for the Treatment of Duchenne Muscular Dystrophy. Journal of personalized medicine. vol 8. issue 4. 2020-10-01. PMID:30477208. |
duchenne muscular dystrophy (dmd) is a fatal x-linked recessive neuromuscular disease prevalent in 1 in 3500 to 5000 males worldwide. |
2020-10-01 |
2023-08-13 |
Not clear |
| Kristy Iskandar, Sunartini, Andika Priamas Nugrahanto, Nissya Ilma, Alvin Santoso Kalim, Guritno Adistyawan, Siswanto, Roni Nanin. Use of air stacking to improve pulmonary function in Indonesian Duchenne muscular dystrophy patients: bridging the standard of care gap in low middle income country setting. BMC proceedings. vol 13. issue Suppl 11. 2020-10-01. PMID:31890014. |
duchenne muscular dystrophy (dmd) is a fatal x-linked recessive neuromuscular disease, characterized by progressive loss of muscle strength. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yanmin Song, Shuai Yao, Yunhai Liu, Lili Long, Huan Yang, Qiuxiang Li, Jinghui Liang, Xinxin Li, Yuling Lu, Haoran Zhu, Ning Zhan. Expression levels of TGF-β1 and CTGF are associated with the severity of Duchenne muscular dystrophy. Experimental and therapeutic medicine. vol 13. issue 4. 2020-09-30. PMID:28413459. |
a total of 18 cases of dmd, which were confirmed by routine pathological diagnosis were recruited into the present study, along with 8 subjects who suffered from acute trauma but did not present any neuromuscular diseases and were enrolled as the healthy controls. |
2020-09-30 |
2023-08-13 |
human |
| Anne Forand, Antoine Muchir, Nathalie Mougenot, Caroline Sevoz-Couche, Cécile Peccate, Mégane Lemaitre, Charlotte Izabelle, Matthew Wood, Stéphanie Lorain, France Piétri-Rouxe. Combined Treatment with Peptide-Conjugated Phosphorodiamidate Morpholino Oligomer-PPMO and AAV-U7 Rescues the Severe DMD Phenotype in Mice. Molecular therapy. Methods & clinical development. vol 17. 2020-09-28. PMID:32346547. |
duchenne muscular dystrophy (dmd) is a devastating neuromuscular disease caused by an absence of the dystrophin protein, which is essential for muscle fiber integrity. |
2020-09-28 |
2023-08-13 |
mouse |
| Virginie Mariot, Caroline Le Guiner, Inès Barthélémy, Marie Montus, Stéphane Blot, Silvia Torelli, Jennifer Morgan, Francesco Muntoni, Thomas Voit, Julie Dumonceau. Myostatin Is a Quantifiable Biomarker for Monitoring Pharmaco-gene Therapy in Duchenne Muscular Dystrophy. Molecular therapy. Methods & clinical development. vol 18. 2020-09-28. PMID:32695843. |
we previously described how the myostatin (mstn) level is naturally downregulated in several neuromuscular diseases, including duchenne muscular dystrophy (dmd). |
2020-09-28 |
2023-08-13 |
dog |
| Eli F Kelley, Troy J Cross, Eric M Snyder, Craig M McDonald, Eric P Hoffman, Luca Bell. Influence of β Respiratory research. vol 20. issue 1. 2020-03-30. PMID:31619245. |
influence of β duchenne muscular dystrophy (dmd) is a progressive neuromuscular disease resulting in severe respiratory derangements. |
2020-03-30 |
2023-08-13 |
Not clear |
| Kristy Iskandar, Ery Kus Dwianingsih, Linda Pratiwi, Alvin Santoso Kalim, Hasna Mardhiah, Alifiani H Putranti, Dian K Nurputra, Agung Triono, Elisabeth S Herini, Rusdy G Malueka, Gunadi, Poh San Lai, Sunartin. The analysis of DMD gene deletions by multiplex PCR in Indonesian DMD/BMD patients: the era of personalized medicine. BMC research notes. vol 12. issue 1. 2020-03-25. PMID:31661024. |
duchenne/becker muscular dystrophy (dmd/bmd) is the most common genetic neuromuscular disease in children, resulting from a defect in the dmd gene located on xp21.2. |
2020-03-25 |
2023-08-13 |
Not clear |
| Claudia R Senesac, Donovan J Lott, Rebecca J Willcocks, Tina Duong, Barbara K Smit. Lower Extremity Functional Outcome Measures in Duchenne Muscular Dystrophy-A Delphi Survey. Journal of neuromuscular diseases. vol 6. issue 1. 2020-01-02. PMID:30562905. |
duchenne muscular dystrophy (dmd) is a progressive neuromuscular disease characterized by progressive muscle weakness, multiple system involvement and premature mortality. |
2020-01-02 |
2023-08-13 |
Not clear |
| Maria K Tsoumpra, Seiji Fukumoto, Toshio Matsumoto, Shin'ichi Takeda, Matthew J A Wood, Yoshitsugu Aok. Peptide-conjugate antisense based splice-correction for Duchenne muscular dystrophy and other neuromuscular diseases. EBioMedicine. vol 45. 2019-12-17. PMID:31257147. |
herein we summarize the main pathophysiological features of dmd and the emergence of ppmos as promising exon skipping agents aiming to rescue defective gene expression in dmd and other neuromuscular diseases. |
2019-12-17 |
2023-08-13 |
Not clear |
| Maricela Rodríguez-Cruz, Oriana Del Rocío Cruz-Guzmán, Tomás Almeida-Becerril, Alan Donovan Solís-Serna, Salvador Atilano-Miguel, Juan Raúl Sánchez-González, Lourdes Barbosa-Cortés, Eugenia Dolores Ruíz-Cruz, Juan Carlos Huicochea, Alan Cárdenas-Conejo, Rosa Elena Escobar-Cedillo, Carlos Alberto Yam-Ontiveros, Edgar F Ricárdez-Marcia. Potential therapeutic impact of omega-3 long chain-polyunsaturated fatty acids on inflammation markers in Duchenne muscular dystrophy: A double-blind, controlled randomized trial. Clinical nutrition (Edinburgh, Scotland). vol 37. issue 6 Pt A. 2019-12-02. PMID:28987470. |
dmd is a neuromuscular disease and its clinical course comprises chronic inflammation and gradual muscle weakness. |
2019-12-02 |
2023-08-13 |
Not clear |
| Aziza Sbiti, Fatiha El Kerch, Abdelaziz Sefian. Analysis of Dystrophin Gene Deletions by Multiplex PCR in Moroccan Patients. Journal of biomedicine & biotechnology. vol 2. issue 3. 2019-11-20. PMID:12488581. |
dmd is the most frequent neuromuscular disease in humans (1/3500 male newborn). |
2019-11-20 |
2023-08-12 |
Not clear |
| C Ribstein, D Courteix, N Rabiau, C Bommelaer, Y Bourdeau, B Pereira, Catherine Sarre. Secondary Bone Defect in Neuromuscular Diseases in Childhood: A Longitudinal "Muscle-Bone Unit" Analysis. Neuropediatrics. vol 49. issue 6. 2019-10-22. PMID:29980148. |
to evaluate the potential bone defect in neuromuscular diseases, we conducted a longitudinal study including three groups of patients: 14 duchenne muscular dystrophies (dmd) and 2 limb-girdle muscular dystrophies (lgmd); 3 becker muscular dystrophies (bemd) and 7 spinal muscular atrophies (sma). |
2019-10-22 |
2023-08-13 |
Not clear |
| Taeyoung Koo, Ngoc B Lu-Nguyen, Alberto Malerba, Eunji Kim, Daesik Kim, Ornella Cappellari, Hee-Yeon Cho, George Dickson, Linda Popplewell, Jin-Soo Ki. Functional Rescue of Dystrophin Deficiency in Mice Caused by Frameshift Mutations Using Campylobacter jejuni Cas9. Molecular therapy : the journal of the American Society of Gene Therapy. vol 26. issue 6. 2019-06-11. PMID:29730196. |
this work suggests that in vivo dmd frame correction, mediated by cjcas9, has great potential for the treatment of dmd and other neuromuscular diseases. |
2019-06-11 |
2023-08-13 |
mouse |
| Masafumi Matsuo, Hiroyuki Awano, Nobuhiro Maruyama, Hisahide Nishi. Titin fragment in urine: A noninvasive biomarker of muscle degradation. Advances in clinical chemistry. vol 90. 2019-06-05. PMID:31122607. |
enzyme-linked immunosorbent assays (elisas) have shown that urinary titin is a useful noninvasive biomarker for the diagnosis and screening of not only dmd, but also of neuromuscular diseases, for predicting the outcome of cardiomyopathy and for evaluating physical activities. |
2019-06-05 |
2023-08-13 |
Not clear |
| Hannah R Spaulding, Joshua T Selsb. Is Exercise the Right Medicine for Dystrophic Muscle? Medicine and science in sports and exercise. vol 50. issue 9. 2019-05-01. PMID:29649068. |
duchenne muscular dystrophy (dmd) is a neuromuscular disease caused by a dystrophin protein deficiency. |
2019-05-01 |
2023-08-13 |
Not clear |
| Tatianna Wai Ying Wong, Ronald D Coh. Therapeutic Applications of CRISPR/Cas for Duchenne Muscular Dystrophy. Current gene therapy. vol 17. issue 4. 2019-04-09. PMID:29173172. |
duchenne muscular dystrophy (dmd) is an x-linked neuromuscular disease caused by the lack of dystrophin due to mutations in the dmd gene. |
2019-04-09 |
2023-08-13 |
Not clear |
| Jordan E Balke, Ling Zhang, Justin M Perciva. Neuronal nitric oxide synthase (nNOS) splice variant function: Insights into nitric oxide signaling from skeletal muscle. Nitric oxide : biology and chemistry. vol 82. 2019-03-12. PMID:30503614. |
defects in neuronal nitric oxide synthase (nnos) splice variant localization and signaling in skeletal muscle are a firmly established pathogenic characteristic of many neuromuscular diseases, including duchenne and becker muscular dystrophy (dmd and bmd, respectively). |
2019-03-12 |
2023-08-13 |
mouse |
| David J Birnkrant, Katharine Bushby, Carla M Bann, Susan D Apkon, Angela Blackwell, David Brumbaugh, Laura E Case, Paula R Clemens, Stasia Hadjiyannakis, Shree Pandya, Natalie Street, Jean Tomezsko, Kathryn R Wagner, Leanne M Ward, David R Webe. Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and neuromuscular, rehabilitation, endocrine, and gastrointestinal and nutritional management. The Lancet. Neurology. vol 17. issue 3. 2019-02-07. PMID:29395989. |
since the publication of the duchenne muscular dystrophy (dmd) care considerations in 2010, multidisciplinary care of this severe, progressive neuromuscular disease has evolved. |
2019-02-07 |
2023-08-13 |
Not clear |
| Nevenka Juretić, Josefina Díaz, Felipe Romero, Gustavo González, Enrique Jaimovich, Nora Rivero. Interleukin-6 and neuregulin-1 as regulators of utrophin expression via the activation of NRG-1/ErbB signaling pathway in mdx cells. Biochimica et biophysica acta. Molecular basis of disease. vol 1863. issue 3. 2018-11-26. PMID:27988307. |
duchenne muscular dystrophy (dmd) is a neuromuscular disease originated by mutations in the dystrophin gene. |
2018-11-26 |
2023-08-13 |
Not clear |
| Chantal Beekman, Anneke A Janson, Aabed Baghat, Judith C van Deutekom, Nicole A Datso. Use of capillary Western immunoassay (Wes) for quantification of dystrophin levels in skeletal muscle of healthy controls and individuals with Becker and Duchenne muscular dystrophy. PloS one. vol 13. issue 4. 2018-07-30. PMID:29641567. |
duchenne muscular dystrophy (dmd) is a neuromuscular disease characterized by progressive weakness of the skeletal and cardiac muscles. |
2018-07-30 |
2023-08-13 |
Not clear |