| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Natalia Areiza Mazo, Valentina Echeverria, Ricardo Cabezas, Marco Avila-Rodriguez, Vadim V Tarasov, Nagendra S Yarla, Gjumrakch Aliev, George E Barret. Medicinal Plants as Protective Strategies Against Parkinson's Disease. Current pharmaceutical design. vol 23. issue 28. 2018-07-05. PMID:28302024. |
parkinson's disease is a neurodegenerative disease caused by the loss of dopaminergic neurons in the substantia nigra pars compacta region. |
2018-07-05 |
2023-08-13 |
Not clear |
| Itzia Jimenez-Ferrer, Michael Jewett, Ashmita Tontanahal, Marina Romero-Ramos, Maria Swanber. Allelic difference in Mhc2ta confers altered microglial activation and susceptibility to α-synuclein-induced dopaminergic neurodegeneration. Neurobiology of disease. vol 106. 2018-05-15. PMID:28736195. |
parkinson's disease (pd) is a complex and heterogeneous neurodegenerative disease characterized by a progressive loss of dopaminergic neurons in the substantia nigra pars compacta and pathological intracellular accumulation of alpha-synuclein (α-syn). |
2018-05-15 |
2023-08-13 |
human |
| Kamal Awad, Abdelrahman Ibrahim Abushouk, Ahmed Helal AbdelKarim, Maged Mohammed, Ahmed Negida, Ali S Shalas. Bee venom for the treatment of Parkinson's disease: How far is it possible? Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 91. 2018-03-26. PMID:28477460. |
parkinson's disease (pd) is the second most common neurodegenerative disease, characterized by progressive loss of dopaminergic neurons in the substantia nigra pars compacta leading to depletion of striatal dopamine and motor symptoms as bradykinesia, resting tremors, rigidity, and postural instability. |
2018-03-26 |
2023-08-13 |
bee |
| Siamak Afshin-Majd, Keyhan Bashiri, Zahra Kiasalari, Tourandokht Baluchnejadmojarad, Reza Sedaghat, Mehrdad Roghan. Acetyl-l-carnitine protects dopaminergic nigrostriatal pathway in 6-hydroxydopamine-induced model of Parkinson's disease in the rat. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 89. 2018-02-27. PMID:28199883. |
parkinson's disease (pd) is a movement disorder and the second most common neurodegenerative disease worldwide in which nigrostriatal dopaminergic neurons within substantia nigra pars compacta (snc) are lost, with clinical motor and non-motor symptoms including bradykinesia, resting tremor, rigidity, stooping posture and cognitive deficits. |
2018-02-27 |
2023-08-13 |
rat |
| Joseph R Phillips, Abeer M Eissa, Doaa H Hewedi, Marjan Jahanshahi, Mohamed El-Gamal, Szabolcs Keri, Ahmed A Moustaf. Neural substrates and potential treatments for levodopa-induced dyskinesias in Parkinson's disease. Reviews in the neurosciences. vol 27. issue 7. 2018-01-02. PMID:27362959. |
pd is a neurodegenerative disease, with dopaminergic neuronal loss occurring in the substantia nigra pars compacta, thus disrupting basal ganglia functions. |
2018-01-02 |
2023-08-13 |
Not clear |
| Zhange Yu, Shuai Zhang, Dongdong Wang, Meng Fan, Fuqiang Gao, Wei Sun, Zirong Li, Shiliang L. The significance of uric acid in the diagnosis and treatment of Parkinson disease: An updated systemic review. Medicine. vol 96. issue 45. 2017-12-04. PMID:29137045. |
parkinson disease (pd) is a neurodegenerative disease characterized by chronic and progressive loss of dopaminergic neurons in substansia nigra pars compacta. |
2017-12-04 |
2023-08-13 |
Not clear |
| Yeomoon Sim, Gunhyuk Park, Hyeyoon Eo, Eugene Huh, Pil Sung Gu, Seon-Pyo Hong, Youngmi Kim Pak, Myung Sook O. Protective effects of a herbal extract combination of Bupleurum falcatum, Paeonia suffruticosa, and Angelica dahurica against MPTP-induced neurotoxicity via regulation of nuclear receptor-related 1 protein. Neuroscience. vol 340. 2017-11-06. PMID:27771535. |
parkinson's disease (pd) is one of the progressive neurodegenerative diseases of whose condition is characterized by dopaminergic neuronal cell loss and dysfunction in the substantia nigra pars compacta (snpc) and the striatum. |
2017-11-06 |
2023-08-13 |
mouse |
| Xue-Yuan Niu, Hou-Ju Huang, Jin-Bao Zhang, Chan Zhang, Wei-Guang Chen, Chen-You Sun, Yu-Qiang Ding, Min Lia. Deletion of autophagy-related gene 7 in dopaminergic neurons prevents their loss induced by MPTP. Neuroscience. vol 339. 2017-10-30. PMID:27693472. |
parkinson's disease (pd) is a neurodegenerative disease caused by a gradual loss of midbrain dopaminergic (mda) neurons in the substantia nigra pars compacta (snpc) during aging. |
2017-10-30 |
2023-08-13 |
mouse |
| Jenny Sassone, GiuliaMaia Serratto, Flavia Valtorta, Vincenzo Silani, Maria Passafaro, Andrea Ciammol. The synaptic function of parkin. Brain : a journal of neurology. vol 140. issue 9. 2017-10-30. PMID:28335015. |
loss of function mutations in the gene park2, which encodes the protein parkin, cause autosomal recessive juvenile parkinsonism, a neurodegenerative disease characterized by degeneration of the dopaminergic neurons localized in the substantia nigra pars compacta. |
2017-10-30 |
2023-08-13 |
Not clear |
| Qingxi Zhang, Wanling Chen, Sheng Tan, Tongxiang Li. Stem Cells for Modeling and Therapy of Parkinson's Disease. Human gene therapy. vol 28. issue 1. 2017-08-23. PMID:27762639. |
parkinson's disease (pd) is the second most frequent neurodegenerative disease after alzheimer's disease, which is characterized by a low level of dopamine being expressing in the striatum and a deterioration of dopaminergic neurons (dan) in the substantia nigra pars compacta. |
2017-08-23 |
2023-08-13 |
human |
| Sandy Stayte, Peggy Rentsch, Anna R Tröscher, Maximilian Bamberger, Kong M Li, Bryce Visse. Activin A Inhibits MPTP and LPS-Induced Increases in Inflammatory Cell Populations and Loss of Dopamine Neurons in the Mouse Midbrain In Vivo. PloS one. vol 12. issue 1. 2017-08-10. PMID:28121982. |
parkinson's disease is a chronic neurodegenerative disease characterized by a significant loss of dopaminergic neurons within the substantia nigra pars compacta region and a subsequent loss of dopamine within the striatum. |
2017-08-10 |
2023-08-13 |
mouse |
| Christiane Mourre, Christine Manrique, Jeremy Camon, Sabrine Aidi-Knani, Thierry Deltheil, Nathalie Turle-Lorenzo, Gaelle Guiraudie-Capraz, Marianne Amalri. Changes in SK channel expression in the basal ganglia after partial nigrostriatal dopamine lesions in rats: Functional consequences. Neuropharmacology. vol 113. issue Pt A. 2017-07-11. PMID:27825825. |
parkinson's disease (pd) is a progressive neurodegenerative disease originating from the loss of dopamine (da) neurons in the substantia nigra pars compacta (snc). |
2017-07-11 |
2023-08-13 |
rat |
| Willyan Franco Hilario, Alice Laschuk Herlinger, Lorena Bianchine Areal, Lívia Silveira de Moraes, Tamara Andrea Alarcon Ferreira, Tassiane Emanuelle Servane Andrade, Cristina Martins-Silva, Rita Gomes Wanderley Pire. Cholinergic and Dopaminergic Alterations in Nigrostriatal Neurons Are Involved in Environmental Enrichment Motor Protection in a Mouse Model of Parkinson's Disease. Journal of molecular neuroscience : MN. vol 60. issue 4. 2017-03-23. PMID:27660217. |
parkinson's disease (pd) is the second most common neurodegenerative disease in the world, being characterized by dopaminergic neurodegeneration of substantia nigra pars compacta. |
2017-03-23 |
2023-08-13 |
mouse |
| Ben Newland, Paul Wolff, Dezhong Zhou, Wei Wang, Hong Zhang, Anne Rosser, Wenxin Wang, Carsten Werne. Synthesis of ROS scavenging microspheres from a dopamine containing poly(β-amino ester) for applications for neurodegenerative disorders. Biomaterials science. vol 4. issue 3. 2017-02-06. PMID:26756041. |
parkinson's disease (pd) is a common neurodegenerative disease characterized by a substantial decrease of dopaminergic neurons in the substantia nigra pars compacta. |
2017-02-06 |
2023-08-13 |
rat |
| Shreesh Ojha, Hayate Javed, Sheikh Azimullah, M Emdadul Haqu. β-Caryophyllene, a phytocannabinoid attenuates oxidative stress, neuroinflammation, glial activation, and salvages dopaminergic neurons in a rat model of Parkinson disease. Molecular and cellular biochemistry. vol 418. issue 1-2. 2017-02-02. PMID:27316720. |
parkinson disease (pd) is a neurodegenerative disease characterized by progressive dopaminergic neurodegeneration in the substantia nigra pars compacta (snc) area. |
2017-02-02 |
2023-08-13 |
rat |
| Shuei Sugama, Kazunari Sekiyama, Tohru Kodama, Yoshiki Takamatsu, Takato Takenouchi, Makoto Hashimoto, Conti Bruno, Yoshihiko Kakinum. Chronic restraint stress triggers dopaminergic and noradrenergic neurodegeneration: Possible role of chronic stress in the onset of Parkinson's disease. Brain, behavior, and immunity. vol 51. 2017-01-10. PMID:26291405. |
parkinson's disease (pd) is a neurodegenerative disease characterized by the loss of dopaminergic (da) neurons in the substantia nigra pars compacta (snpc) and, to a lesser extent, in the noradrenergic neurons of the locus coeruleus (lc). |
2017-01-10 |
2023-08-13 |
rat |
| Kai Tao, Bao Wang, Dayun Feng, Wei Zhang, Fangfang Lu, Juan Lai, Lu Huang, Tiejian Nie, Qian Yan. Salidroside Protects Against 6-Hydroxydopamine-Induced Cytotoxicity by Attenuating ER Stress. Neuroscience bulletin. vol 32. issue 1. 2016-11-03. PMID:26762342. |
parkinson's disease (pd) is a neurodegenerative disease characterized by a persistent decline of dopaminergic (da) neurons in the substantia nigra pars compacta. |
2016-11-03 |
2023-08-13 |
Not clear |
| Qunli Cui, Xin Li, Hongcan Zh. Curcumin ameliorates dopaminergic neuronal oxidative damage via activation of the Akt/Nrf2 pathway. Molecular medicine reports. vol 13. issue 2. 2016-10-31. PMID:26648392. |
parkinson's disease (pd) is an age-related complex neurodegenerative disease that affects ≤ 80% of dopaminergic neurons in the substantia nigra pars compacta (snpc). |
2016-10-31 |
2023-08-13 |
rat |
| Jun Wang, Can He, Wang-Yang Wu, Feng Chen, Yang-Yang Wu, Wei-Zu Li, Han-Qing Chen, Yan-Yan Yi. Biochanin A protects dopaminergic neurons against lipopolysaccharide-induced damage and oxidative stress in a rat model of Parkinson's disease. Pharmacology, biochemistry, and behavior. vol 138. 2016-07-28. PMID:26394281. |
parkinson's disease (pd) is the second most common neurodegenerative disease, which is characterized by loss of dopaminergic neurons in the substantia nigra pars compacta (snpc). |
2016-07-28 |
2023-08-13 |
rat |
| Qingsong Hu, Guanghui Wan. Mitochondrial dysfunction in Parkinson's disease. Translational neurodegeneration. vol 5. 2016-07-25. PMID:27453777. |
parkinson's disease (pd) is the second most common neurodegenerative disease, which is characterized by loss of dopaminergic (da) neurons in the substantia nigra pars compacta and the formation of lewy bodies and lewy neurites in surviving da neurons in most cases. |
2016-07-25 |
2023-08-13 |
Not clear |