| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Narttaya Chaiwiang, Teera Poyomti. Microbial dysbiosis and microbiota-gut-retina axis: The lesson from brain neurodegenerative diseases to primary open-angle glaucoma pathogenesis of autoimmunity. Acta microbiologica et immunologica Hungarica. vol 66. issue 4. 2020-04-14. PMID:31786943. |
however, primary open-angle glaucoma (poag), known as a complex neurodegenerative disease resulting from retinal ganglion cell death and optic nerve damage, can cause irreversible blindness and visual field loss. |
2020-04-14 |
2023-08-13 |
Not clear |
| Claudia Rossi, Ilaria Cicalini, Maria Concetta Cufaro, Luca Agnifili, Leonardo Mastropasqua, Paola Lanuti, Marco Marchisio, Vincenzo De Laurenzi, Piero Del Boccio, Damiana Pieragostin. Multi-Omics Approach for Studying Tears in Treatment-Naïve Glaucoma Patients. International journal of molecular sciences. vol 20. issue 16. 2020-01-09. PMID:31426571. |
primary open-angle glaucoma (poag) represents the leading cause of irreversible blindness worldwide and is a multifactorial, chronic neurodegenerative disease characterized by retinal ganglion cell and visual field loss. |
2020-01-09 |
2023-08-13 |
human |
| Zai-Long Chi, Avner Adini, Amy E Birsner, Lauren Bazinet, James D Akula, Robert J D'Amat. PR1P ameliorates neurodegeneration through activation of VEGF signaling pathway and remodeling of the extracellular environment. Neuropharmacology. vol 148. 2019-12-27. PMID:30594697. |
optic neuropathies are the most commonly occurring neurodegenerative diseases, characterized by progressive retinal ganglion cell (rgc) degeneration. |
2019-12-27 |
2023-08-13 |
rat |
| Jia-Jian Wang, Kun Shan, Bai-Hui Liu, Chang Liu, Rong-Mei Zhou, Xiu-Miao Li, Rui Dong, Shu-Jie Zhang, Sheng-Hai Zhang, Ji-Hong Wu, Biao Ya. Targeting circular RNA-ZRANB1 for therapeutic intervention in retinal neurodegeneration. Cell death & disease. vol 9. issue 5. 2019-11-07. PMID:29748605. |
glaucoma is a neurodegenerative disease characterized by retinal ganglion cell (rgc) loss, optic disc excavation, and progressive visual field loss. |
2019-11-07 |
2023-08-13 |
Not clear |
| Fabian Anders, Aiwei Liu, Carolina Mann, Julia Teister, Jasmin Lauzi, Solon Thanos, Franz H Grus, Norbert Pfeiffer, Verena Prokosc. The Small Heat Shock Protein α-Crystallin B Shows Neuroprotective Properties in a Glaucoma Animal Model. International journal of molecular sciences. vol 18. issue 11. 2018-06-22. PMID:29135941. |
glaucoma is a neurodegenerative disease that leads to irreversible retinal ganglion cell (rgc) loss and is one of the main causes of blindness worldwide. |
2018-06-22 |
2023-08-13 |
Not clear |
| Shiama I Balendra, Parth Arvind Shah, Mishank Jain, Andrzej Grzybowski, Maria F Cordeir. Glaucoma: Hot Topics in Pharmacology. Current pharmaceutical design. vol 23. issue 4. 2017-12-22. PMID:27897119. |
glaucoma comprises a group of neurodegenerative diseases resulting in retinal ganglion cell death within the optic nerve head. |
2017-12-22 |
2023-08-13 |
Not clear |
| Jeffrey M Gidday, Lihong Zhang, Chia-Wen Chiang, Yanli Zh. Enhanced Retinal Ganglion Cell Survival in Glaucoma by Hypoxic Postconditioning After Disease Onset. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 12. issue 2. 2016-03-30. PMID:25549850. |
recently, in a mouse model of glaucoma, we demonstrated retinal ganglion cell (rgc) protection by repetitively "preconditioning" with hypoxia prior to disease onset, indicating an epigenetic approach may also yield benefits in chronic neurodegenerative disease. |
2016-03-30 |
2023-08-13 |
mouse |
| Dorota Skowronska-Krawczyk, Ling Zhao, Jie Zhu, Robert N Weinreb, Guiqun Cao, Jing Luo, Ken Flagg, Sherrina Patel, Cindy Wen, Martin Krupa, Hongrong Luo, Hong Ouyang, Danni Lin, Wenqiu Wang, Gen Li, Yanxin Xu, Oulan Li, Christopher Chung, Emily Yeh, Maryam Jafari, Michael Ai, Zheng Zhong, William Shi, Lianghong Zheng, Michal Krawczyk, Daniel Chen, Catherine Shi, Carolyn Zin, Jin Zhu, Pamela L Mellon, Weiwei Gao, Ruben Abagyan, Liangfang Zhang, Xiaodong Sun, Sheng Zhong, Yehong Zhuo, Michael G Rosenfeld, Yizhi Liu, Kang Zhan. P16INK4a Upregulation Mediated by SIX6 Defines Retinal Ganglion Cell Pathogenesis in Glaucoma. Molecular cell. vol 59. issue 6. 2015-12-21. PMID:26365380. |
glaucoma, a blinding neurodegenerative disease, whose risk factors include elevated intraocular pressure (iop), age, and genetics, is characterized by accelerated and progressive retinal ganglion cell (rgc) death. |
2015-12-21 |
2023-08-13 |
mouse |
| Kolko . Present and New Treatment Strategies in the Management of Glaucoma. The open ophthalmology journal. vol 9. 2015-06-13. PMID:26069521. |
glaucoma is a neurodegenerative disease characterized by retinal ganglion cell (rgc) death and axonal loss. |
2015-06-13 |
2023-08-13 |
human |
| Jiahua Fang, Fagang Jiang, Jingbo Li, Yanhua Zh. Rationale for the use of multifunctional drugs as neuroprotective agents for glaucoma. Neural regeneration research. vol 7. issue 4. 2015-03-25. PMID:25806075. |
glaucoma, the leading cause globally of irreversible blindness, is a neurodegenerative disease characterized by progressive retinal ganglion cell death. |
2015-03-25 |
2023-08-13 |
Not clear |
| Margo S Clark. Regional pathology in glaucoma--an overlooked link to neuroprotective strategies. Medical hypotheses. vol 80. issue 6. 2013-12-02. PMID:23557847. |
it is a neurodegenerative disease characterized by retinal ganglion cell loss. |
2013-12-02 |
2023-08-12 |
Not clear |
| Thomas V Johnson, Keith R Marti. Cell transplantation approaches to retinal ganglion cell neuroprotection in glaucoma. Current opinion in pharmacology. vol 13. issue 1. 2013-05-28. PMID:22939899. |
glaucoma is a complex neurodegenerative disease that involves interactions among multiple signaling pathways, ultimately leading to progressive retinal ganglion cell (rgc) death. |
2013-05-28 |
2023-08-12 |
Not clear |
| M Agudo-Barriuso, M P Villegas-Pérez, J Miralles de Imperial, M Vidal-San. Anatomical and functional damage in experimental glaucoma. Current opinion in pharmacology. vol 13. issue 1. 2013-05-28. PMID:23041078. |
glaucoma is a progressive neurodegenerative disease caused by retinal ganglion cell (rgc) loss. |
2013-05-28 |
2023-08-12 |
Not clear |
| Barbara Lorber, Alessandra Guidi, James W Fawcett, Keith R Marti. Activated retinal glia mediated axon regeneration in experimental glaucoma. Neurobiology of disease. vol 45. issue 1. 2012-07-23. PMID:21867754. |
glaucoma, a leading cause of blindness, is a neurodegenerative disease characterized by progressive loss of retinal ganglion cell axons in the optic nerve and their cell bodies in the retina. |
2012-07-23 |
2023-08-12 |
rat |
| R Scott Duncan, Hua Xin, Daryl L Goad, Kent D Chapman, Peter Koule. Protection of neurons in the retinal ganglion cell layer against excitotoxicity by the N-acylethanolamine, N-linoleoylethanolamine. Clinical ophthalmology (Auckland, N.Z.). vol 5. 2011-07-14. PMID:21573043. |
retinal ganglion cell (rgc) death is a hallmark of neurodegenerative diseases and disease processes of the eye, including glaucoma. |
2011-07-14 |
2023-08-12 |
Not clear |
| Anna Galanopoulos, Ivan Goldber. Clinical efficacy and neuroprotective effects of brimonidine in the management of glaucoma and ocular hypertension. Clinical ophthalmology (Auckland, N.Z.). vol 3. 2011-05-26. PMID:19668554. |
elevated intraocular pressure (iop) is a significant risk factor for the development and progression of glaucomatous optic neuropathy, but increasingly we appreciate that non-pressure dependent factors, are key to our understanding of the pathophysiology of these neurodegenerative diseases, that target the retinal ganglion cell. |
2011-05-26 |
2023-08-12 |
human |
| A H Dahlmann-Noor, S Vijay, G Astrid Limb, P T Kha. Strategies for optic nerve rescue and regeneration in glaucoma and other optic neuropathies. Drug discovery today. vol 15. issue 7-8. 2010-06-17. PMID:20197108. |
glaucoma is a neurodegenerative disease in which various triggers induce cascades of secondary events, which ultimately lead to apoptotic retinal ganglion cell (rgc) death. |
2010-06-17 |
2023-08-12 |
Not clear |
| Christopher L Daugherty, Hilda Curtis, Tony Realini, Judie F Charlton, Sepideh Zarepars. Primary open angle glaucoma in a Caucasian population is associated with the p53 codon 72 polymorphism. Molecular vision. vol 15. 2009-10-28. PMID:19784392. |
apoptosis has been implicated as the mechanism for retinal ganglion cell death in primary open-angle glaucoma (poag), a complex neurodegenerative disease. |
2009-10-28 |
2023-08-12 |
Not clear |
| Joel A Dietz, Yan Li, Lisa M Chung, Brian S Yandell, Cassandra L Schlamp, Robert W Nickell. Rgcs1, a dominant QTL that affects retinal ganglion cell death after optic nerve crush in mice. BMC neuroscience. vol 9. 2008-09-10. PMID:18671875. |
retinal ganglion cell death is a defining feature of the chronic and genetically complex neurodegenerative disease glaucoma. |
2008-09-10 |
2023-08-12 |
mouse |
| J García-Campos, A Villena, F Díaz, L Vidal, M Moreno, I Pérez de Varga. Morphological and functional changes in experimental ocular hypertension and role of neuroprotective drugs. Histology and histopathology. vol 22. issue 12. 2007-09-14. PMID:17701920. |
glaucoma is a neurodegenerative disease characterized by progressive loss of retinal ganglion cell axons and their cell bodies in the retina. |
2007-09-14 |
2023-08-12 |
rat |