| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gabriella E Parrilla, Akanksha Salkar, Roshana Vander Wall, Vivek Gupta, Stuart L Graham, Yuyi Yo. Glaucoma, More than Meets the Eye: Patterns of Demyelination Revealed in Human Postmortem Glaucomatous Optic Nerve. Aging and disease. 2024-09-03. PMID:39226160. |
glaucoma is a neurodegenerative disease affecting millions worldwide, characterised by retinal ganglion cell (rgc) degeneration which leads to blindness in more advanced cases. |
2024-09-03 |
2024-09-06 |
human |
| Gabriella E Parrilla, Akanksha Salkar, Roshana Vander Wall, Vivek Gupta, Stuart L Graham, Yuyi Yo. Glaucoma, More than Meets the Eye: Patterns of Demyelination Revealed in Human Postmortem Glaucomatous Optic Nerve. Aging and disease. vol 15. issue 5. 2024-08-27. PMID:39191397. |
glaucoma is a neurodegenerative disease affecting millions worldwide, characterised by retinal ganglion cell (rgc) degeneration which leads to blindness in more advanced cases. |
2024-08-27 |
2024-08-30 |
human |
| Gloria Cimaglia, James R Tribble, Marcela Votruba, Pete A Williams, James E Morga. Oral nicotinamide provides robust, dose-dependent structural and metabolic neuroprotection of retinal ganglion cells in experimental glaucoma. Acta neuropathologica communications. vol 12. issue 1. 2024-08-24. PMID:39180087. |
advances in our understanding of retinal ganglion cell metabolic profiles shed light on the energetic shift that triggers early neuronal changes in neurodegenerative diseases. |
2024-08-24 |
2024-08-27 |
human |
| Wenbing Jiang, Dongchang Xiao, Cheng Wu, Jiaqi Yang, Xinghua Peng, Linfeng Chen, Jiamin Zhang, Gaofeng Zha, Wei Li, Rong Ju, Mengqing Xiang, Zhi Xi. Circular RNA-based therapy provides sustained and robust neuroprotection for retinal ganglion cells. Molecular therapy. Nucleic acids. vol 35. issue 3. 2024-07-24. PMID:39045516. |
ocular neurodegenerative diseases like glaucoma lead to progressive retinal ganglion cell (rgc) loss, causing irreversible vision impairment. |
2024-07-24 |
2024-07-26 |
mouse |
| Won-Kyu Ju, Yonju Ha, Seunghwan Choi, Keun-Young Kim, Tonking Bastola, Jungsu Kim, Robert N Weinreb, Wenbo Zhang, Yury I Miller, Soo-Ho Cho. Restoring AIBP deficiency in the retina provides neuroprotection in glaucoma. bioRxiv : the preprint server for biology. 2023-10-31. PMID:37905114. |
glaucoma is a neurodegenerative disease manifested in retinal ganglion cell (rgc) death and irreversible blindness. |
2023-10-31 |
2023-11-08 |
mouse |
| Jingling Zou, Jia Yang, Biyue Chen, Jikuan Jiang, Jingyuan Liu, Cong Wang, Juan Yu, Qinghua Peng, Jun Zeng, Lusi Zhang, Bing Jian. Melatonin protects against NMDA-induced retinal ganglion cell injury by regulating the microglia-TNFα-RGC p38 MAPK pathway. International immunopharmacology. vol 118. 2023-04-26. PMID:37098655. |
glaucoma, one of the most common ocular neurodegenerative diseases worldwide, is characterized by retinal ganglion cell (rgc) loss. |
2023-04-26 |
2023-08-14 |
Not clear |
| Zhou Zeng, Mengling You, Cong Fan, Rong Rong, Haibo Li, Xiaobo Xi. Pathologically high intraocular pressure induces mitochondrial dysfunction through Drp1 and leads to retinal ganglion cell PANoptosis in glaucoma. Redox biology. vol 62. 2023-03-29. PMID:36989574. |
glaucoma is a common neurodegenerative disease characterized by progressive retinal ganglion cell (rgc) loss and visual field defects. |
2023-03-29 |
2023-08-14 |
Not clear |
| Devaraj Basavarajappa, Vivek Gupta, Roshana Vander Wall, Veer Gupta, Nitin Chitranshi, Seyed Shahab Oddin Mirshahvaladi, Viswanthram Palanivel, Yuyi You, Mehdi Mirzaei, Alexander Klistorner, Stuart L Graha. S1PR1 signaling attenuates apoptosis of retinal ganglion cells via modulation of cJun/Bim cascade and Bad phosphorylation in a mouse model of glaucoma. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 37. issue 1. 2022-12-15. PMID:36520045. |
glaucoma is a complex neurodegenerative disease characterized by optic nerve damage and apoptotic retinal ganglion cell (rgc) death, and is the leading cause of irreversible blindness worldwide. |
2022-12-15 |
2023-08-14 |
mouse |
| Rupali Vohra, Berta Sanz-Morello, Anna Luna Mølgaard Tams, Zaynab Ahmad Mouhammad, Kristine Karla Freude, Jens Hannibal, Blanca Irene Aldana, Linda Hildegaard Bergersen, Miriam Kolk. Prevention of Cell Death by Activation of Hydroxycarboxylic Acid Receptor 1 (GPR81) in Retinal Explants. Cells. vol 11. issue 13. 2022-07-09. PMID:35805182. |
progressive retinal ganglion cell (rgc) dysfunction and death are common characteristics of retinal neurodegenerative diseases. |
2022-07-09 |
2023-08-14 |
Not clear |
| Xuejin Zhang, Rong Zhang, Jihong W. Inhibition of the NR2B-PSD95 interaction exerts neuroprotective effects on retinal ischemia-reperfusion injury. Neuroscience. 2022-03-08. PMID:35257794. |
glaucoma is a neurodegenerative disease characterized by progressive retinal ganglion cell (rgc) death. |
2022-03-08 |
2023-08-13 |
rat |
| Ningzhi Zhang, Xuejun He, Yiqiao Xing, Ning Yan. Differential susceptibility of retinal ganglion cell subtypes against neurodegenerative diseases. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. 2022-01-17. PMID:35038014. |
differential susceptibility of retinal ganglion cell subtypes against neurodegenerative diseases. |
2022-01-17 |
2023-08-13 |
Not clear |
| Ning Yang, Juan Yang, Xuejun He, Wenxi Zhang, Yiqiao Xin. Construction and analysis of mRNA, lncRNA, and transcription factor regulatory networks after retinal ganglion cell injury. Experimental eye research. 2021-12-31. PMID:34971620. |
retinal ganglion cell (rgc) injury is a critical pathological feature of several optic neurodegenerative diseases. |
2021-12-31 |
2023-08-13 |
Not clear |
| Gülgün Teze. Multifactorial Pathogenic Processes of Retinal Ganglion Cell Degeneration in Glaucoma towards Multi-Target Strategies for Broader Treatment Effects. Cells. vol 10. issue 6. 2021-10-29. PMID:34199494. |
glaucoma is a chronic neurodegenerative disease characterized by apoptosis of retinal ganglion cell (rgc) somas, degeneration of axons, and loss of synapses at dendrites and axon terminals. |
2021-10-29 |
2023-08-13 |
Not clear |
| Assraa Hassan Jassim, McKay Cavanaugh, Jessica Stukel Shah, Rebecca Willits, Denise M Inma. Transcorneal Electrical Stimulation Reduces Neurodegenerative Process in a Mouse Model of Glaucoma. Annals of biomedical engineering. vol 49. issue 2. 2021-10-05. PMID:32974756. |
glaucoma is a neurodegenerative disease in which the retinal ganglion cell axons of the optic nerve degenerate concomitant with synaptic changes in the retina, leading finally to death of the retinal ganglion cells (rgcs). |
2021-10-05 |
2023-08-13 |
mouse |
| Sergio C Saccà, Stefania Vernazza, Eugenio Luigi Iorio, Sara Tirendi, Anna Maria Bassi, Stefano Gandolfi, Alberto Izzott. Molecular changes in glaucomatous trabecular meshwork. Correlations with retinal ganglion cell death and novel strategies for neuroprotection. Progress in brain research. vol 256. issue 1. 2021-07-05. PMID:32958211. |
glaucoma is a chronic neurodegenerative disease characterized by retinal ganglion cell loss. |
2021-07-05 |
2023-08-13 |
Not clear |
| Ashish Bhandari, Jennie C Smith, Yang Zhang, Aaron A Jensen, Lisa Reid, Toni Goeser, Shan Fan, Deepta Ghate, Matthew J Van Hoo. Early-Stage Ocular Hypertension Alters Retinal Ganglion Cell Synaptic Transmission in the Visual Thalamus. Frontiers in cellular neuroscience. vol 13. 2021-04-10. PMID:31607867. |
axonopathy is a hallmark of many neurodegenerative diseases including glaucoma, where elevated intraocular pressure (ocular hypertension, oht) stresses retinal ganglion cell (rgc) axons as they exit the eye and form the optic nerve. |
2021-04-10 |
2023-08-13 |
mouse |
| Masamitsu Shimazawa, Hideaki Har. [Current Status of the Pharmacological Treatment of Glaucoma and Its Prospects]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 141. issue 1. 2021-02-15. PMID:33390449. |
glaucoma, the leading cause of blindness in adults, is a progressive neurodegenerative disease characterized by retinal ganglion cell (rgc) death. |
2021-02-15 |
2023-08-13 |
Not clear |
| Sean J Lee, D'Anne S Duncan, Franklin D Echevarria, William M McLaughlin, Jeremy B Hatcher, Rebecca M Sappingto. Pressure-Induced Alterations in PEDF and PEDF-R Expression: Implications for Neuroprotective Signaling in Glaucoma. Journal of clinical & experimental ophthalmology. vol 6. issue 5. 2020-10-01. PMID:26807306. |
alterations in neuron-glia signaling are implicated in glaucoma, a neurodegenerative disease characterized by retinal ganglion cell (rgc) death. |
2020-10-01 |
2023-08-13 |
Not clear |
| Ana I Ramirez, Rosa de Hoz, Elena Salobrar-Garcia, Juan J Salazar, Blanca Rojas, Daniel Ajoy, Inés López-Cuenca, Pilar Rojas, Alberto Triviño, José M Ramíre. The Role of Microglia in Retinal Neurodegeneration: Alzheimer's Disease, Parkinson, and Glaucoma. Frontiers in aging neuroscience. vol 9. 2020-10-01. PMID:28729832. |
glaucoma is a multifactorial neurodegenerative disease of the optic nerve, characterized by retinal ganglion cell loss. |
2020-10-01 |
2023-08-13 |
Not clear |
| S Daniel, A F Clark, C M McDowel. Subtype-specific response of retinal ganglion cells to optic nerve crush. Cell death discovery. vol 4. 2020-10-01. PMID:30062056. |
glaucoma is a neurodegenerative disease with retinal ganglion cell (rgc) loss, optic nerve degeneration and subsequent vision loss. |
2020-10-01 |
2023-08-13 |
mouse |