| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Masaaki Waragai, Kazunari Sekiyama, Masayo Fujita, Takahiko Tokuda, Makoto Hashimot. Biomarkers for the diagnosis and management of Parkinson's disease. Expert opinion on medical diagnostics. vol 7. issue 1. 2014-03-17. PMID:23530844. |
parkinson's disease (pd) is the most common neurodegenerative disease leading to movement disorders, and is characterized neuropathologically by the progressive loss of dopaminergic neurons, intracellular α-synuclein deposition and the formation of lewy bodies. |
2014-03-17 |
2023-08-12 |
Not clear |
| Jaromir Budzianowsk. [Tobacco--once a medicinal plant. Does it contain substances with medicinal properties?]. Przeglad lekarski. vol 70. issue 10. 2014-02-27. PMID:24501813. |
through the effect of this compound on specific nicotinic cholinergic receptors (nachrs), which interacts with nigrostriatal dopaminergic system as well as the possibility of using nicotine for the treatment of parkinson's disease and other neurodegenerative diseases. |
2014-02-27 |
2023-08-12 |
Not clear |
| Ling Wang, Ying-Qi Zhai, Li-Li Xu, Chen Qiao, Xiu-Lan Sun, Jian-Hua Ding, Ming Lu, Gang H. Metabolic inflammation exacerbates dopaminergic neuronal degeneration in response to acute MPTP challenge in type 2 diabetes mice. Experimental neurology. vol 251. 2014-02-19. PMID:24220636. |
parkinson's disease (pd), one of the most common neurodegenerative diseases, is characterized by the loss of dopaminergic neurons in the substantia nigra. |
2014-02-19 |
2023-08-12 |
mouse |
| J Weetman, M B Wong, S Sharry, A Rcom-H'cheo-Gauthier, W P Gai, A Meedeniya, D L Pountne. Increased SUMO-1 expression in the unilateral rotenone-lesioned mouse model of Parkinson's disease. Neuroscience letters. vol 544. 2014-01-06. PMID:23583339. |
parkinson's disease (pd) is a neurodegenerative disease resulting from progressive loss of dopaminergic nigrostriatal neurons. |
2014-01-06 |
2023-08-12 |
mouse |
| Hao Deng, Kai Gao, Joseph Jankovi. The VPS35 gene and Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 28. issue 5. 2014-01-02. PMID:23536430. |
parkinson's disease (pd), the second most common age-related neurodegenerative disease, is characterized by loss of dopaminergic and nondopaminergic neurons, leading to a variety of motor and nonmotor symptoms. |
2014-01-02 |
2023-08-12 |
Not clear |
| Anamitra Ghosh, Hariharan Saminathan, Arthi Kanthasamy, Vellareddy Anantharam, Huajun Jin, Gautam Sondarva, Dilshan S Harischandra, Ziqing Qian, Ajay Rana, Anumantha G Kanthasam. The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease. The Journal of biological chemistry. vol 288. issue 30. 2013-11-04. PMID:23754278. |
parkinson disease (pd) is a chronic neurodegenerative disease characterized by a slow and progressive degeneration of dopaminergic neurons in substantia nigra. |
2013-11-04 |
2023-08-12 |
mouse |
| Jeffrey R Liddell, Daniel Obando, Joe Liu, George Ganio, Irene Volitakis, Su San Mok, Peter J Crouch, Anthony R White, Rachel Cod. Lipophilic adamantyl- or deferasirox-based conjugates of desferrioxamine B have enhanced neuroprotective capacity: implications for Parkinson disease. Free radical biology & medicine. vol 60. 2013-11-01. PMID:23391576. |
parkinson disease (pd) is a neurodegenerative disease characterized by death of dopaminergic neurons in the substantia nigra region of the brain. |
2013-11-01 |
2023-08-12 |
Not clear |
| Jesse V Veenvliet, Maria T M Alves Dos Santos, Willemieke M Kouwenhoven, Lars von Oerthel, Jamie L Lim, Annemarie J A van der Linden, Marian J A Groot Koerkamp, Frank C P Holstege, Marten P Smid. Specification of dopaminergic subsets involves interplay of En1 and Pitx3. Development (Cambridge, England). vol 140. issue 16. 2013-10-18. PMID:23863478. |
mesodiencephalic dopaminergic (mdda) neurons control locomotion and emotion and are affected in multiple psychiatric and neurodegenerative diseases, including parkinson's disease (pd). |
2013-10-18 |
2023-08-12 |
mouse |
| Gabriela Mercado, Pamela Valdés, Claudio Het. An ERcentric view of Parkinson's disease. Trends in molecular medicine. vol 19. issue 3. 2013-09-19. PMID:23352769. |
parkinson's disease (pd) is the second most common neurodegenerative disease and is characterized by the selective loss of dopaminergic neurons of the substantia nigra pars compacta and the accumulation of intracellular inclusions containing α-synuclein (αsyn). |
2013-09-19 |
2023-08-12 |
human |
| Paolo Calabresi, Anna Castrioto, Massimiliano Di Filippo, Barbara Piccon. New experimental and clinical links between the hippocampus and the dopaminergic system in Parkinson's disease. The Lancet. Neurology. vol 12. issue 8. 2013-09-19. PMID:23867199. |
parkinson's disease is a common progressive neurodegenerative disease, of which the main neuropathological hallmark is dopaminergic neuronal loss. |
2013-09-19 |
2023-08-12 |
Not clear |
| Vladimir Vukicevic, Maria F Rubin de Celis, Gabriela Diaz-Valencia, Stefan R Bornstein, Monika Ehrhart-Bornstei. Modulation of dopaminergic neuronal differentiation from sympathoadrenal progenitors. Journal of molecular neuroscience : MN. vol 48. issue 2. 2013-08-05. PMID:22447400. |
the capacity of sympathoadrenal progenitors from adrenal medulla to generate dopaminergic neurons in vitro makes them an attractive source for replacement therapies of neurodegenerative diseases such as parkinson's disease. |
2013-08-05 |
2023-08-12 |
Not clear |
| Yoichi Imaizumi, Yohei Okada, Wado Akamatsu, Masato Koike, Naoko Kuzumaki, Hideki Hayakawa, Tomoko Nihira, Tetsuro Kobayashi, Manabu Ohyama, Shigeto Sato, Masashi Takanashi, Manabu Funayama, Akiyoshi Hirayama, Tomoyoshi Soga, Takako Hishiki, Makoto Suematsu, Takuya Yagi, Daisuke Ito, Arifumi Kosakai, Kozo Hayashi, Masanobu Shouji, Atsushi Nakanishi, Norihiro Suzuki, Yoshikuni Mizuno, Noboru Mizushima, Masayuki Amagai, Yasuo Uchiyama, Hideki Mochizuki, Nobutaka Hattori, Hideyuki Okan. Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue. Molecular brain. vol 5. 2013-05-15. PMID:23039195. |
parkinson's disease (pd) is a neurodegenerative disease characterized by selective degeneration of dopaminergic neurons in the substantia nigra (sn). |
2013-05-15 |
2023-08-12 |
mouse |
| Russell R A Kitson, Chuan-Hsin Chang, Rui Xiong, Huw E L Williams, Adrienne L Davis, William Lewis, Donna L Dehn, David Siegel, S Mark Roe, Chrisostomos Prodromou, David Ross, Christopher J Mood. Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90. Nature chemistry. vol 5. issue 4. 2013-05-10. PMID:23511419. |
studies on hsp90 inhibition in cells demonstrated the molecular signature of hsp90 inhibitors: decreases in client proteins with compensatory increases in other heat shock proteins in both human breast cancer and dopaminergic neural cells, demonstrating their potential for use in the therapy of cancer or neurodegenerative diseases. |
2013-05-10 |
2023-08-12 |
human |
| Hendrikus J van Heesbeen, Simone Mesman, Jesse V Veenvliet, Marten P Smid. Epigenetic mechanisms in the development and maintenance of dopaminergic neurons. Development (Cambridge, England). vol 140. issue 6. 2013-05-01. PMID:23444349. |
mesodiencephalic dopaminergic (mdda) neurons are located in the ventral mesodiencephalon and are involved in psychiatric disorders and severely affected in neurodegenerative diseases such as parkinson's disease. |
2013-05-01 |
2023-08-12 |
Not clear |
| Chengyu Sheng, Xin Heng, Guannan Zhang, Ran Xiong, Hui Li, Shi Zhang, Shengdi Che. DJ-1 deficiency perturbs microtubule dynamics and impairs striatal neurite outgrowth. Neurobiology of aging. vol 34. issue 2. 2013-04-29. PMID:22609282. |
parkinson's disease (pd) is a common neurodegenerative disease characterized by the selective loss of the dopaminergic (da) neurons in substantia nigra. |
2013-04-29 |
2023-08-12 |
mouse |
| Seongsoo Lee, Yuzuru Imai, Stephan Gehrke, Song Liu, Bingwei L. The synaptic function of LRRK2. Biochemical Society transactions. vol 40. issue 5. 2013-02-26. PMID:22988863. |
mutations in lrrk2 (leucine-rich repeat kinase 2) are the most frequent genetic lesions so far found in familial as well as sporadic forms of pd (parkinson's disease), a neurodegenerative disease characterized by the dysfunction and degeneration of dopaminergic and other neuronal types. |
2013-02-26 |
2023-08-12 |
human |
| Sonia Gandhi, Annika Vaarmann, Zhi Yao, Michael R Duchen, Nicholas W Wood, Andrey Y Abramo. Dopamine induced neurodegeneration in a PINK1 model of Parkinson's disease. PloS one. vol 7. issue 5. 2012-12-13. PMID:22662171. |
parkinson's disease is a common neurodegenerative disease characterised by progressive loss of dopaminergic neurons, leading to dopamine depletion in the striatum. |
2012-12-13 |
2023-08-12 |
Not clear |
| Livia Popa, D Alexa, Alexandrina Rotar, C D Popesc. [Functional electrical stimulation effect on the motor performances in Parkinsonian patients]. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi. vol 116. issue 2. 2012-11-28. PMID:23077933. |
parkinson's disease (pd) is a neurodegenerative disease involving dopaminergic, cholinergic, glutaminergic, serotoninergic and noradrenergic neurons, having as clinical manifestations both motor and non-motor symptoms. |
2012-11-28 |
2023-08-12 |
human |
| Min Kong, Maowen Ba, Hui Liang, Lili Ma, Quntao Yu, Tianxia Yu, Ying Wan. 5'-Aza-dC sensitizes paraquat toxic effects on PC12 cell. Neuroscience letters. vol 524. issue 1. 2012-11-21. PMID:22796470. |
parkinson's disease (pd) is one of the common neurodegenerative diseases that result in the progressive damage of dopaminergic neurons. |
2012-11-21 |
2023-08-12 |
Not clear |
| Kemal Ugur Tufekci, Ralph Meuwissen, Sermin Genc, Kursad Gen. Inflammation in Parkinson's disease. Advances in protein chemistry and structural biology. vol 88. 2012-11-13. PMID:22814707. |
parkinson's disease (pd) is a common neurodegenerative disease that is characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta. |
2012-11-13 |
2023-08-12 |
Not clear |