| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shigemi Kimura, Noriko Miyake, Shiro Ozasa, Hiroe Ueno, Yoshinobu Ohtani, Yutaka Takaoka, Ichizo Nishin. Increase in cathepsin K gene expression in Duchenne muscular dystrophy skeletal muscle. Neuropathology : official journal of the Japanese Society of Neuropathology. 2024-07-17. PMID:39014877. |
here, we encountered a rare case of a 10-year-old patient with asymptomatic dystrophinopathy with no dystrophin expression and investigated the reason for the absence of muscle weakness to obtain therapeutic insights for dmd. |
2024-07-17 |
2024-07-19 |
Not clear |
| Maria Siemionow, Katarzyna Bocian, Katarzyna T Bozyk, Anna Ziemiecka, Krzysztof Siemiono. Chimeric Cell Therapy Transfers Healthy Donor Mitochondria in Duchenne Muscular Dystrophy. Stem cell reviews and reports. 2024-07-17. PMID:39017908. |
duchenne muscular dystrophy (dmd) is a severe x-linked disorder characterized by dystrophin gene mutations and mitochondrial dysfunction, leading to progressive muscle weakness and premature death of dmd patients. |
2024-07-17 |
2024-07-19 |
mouse |
| Dylan Moutachi, Janek Hyzewicz, Pauline Roy, Mégane Lemaitre, Damien Bachasson, Helge Amthor, Olli Ritvos, Zhenlin Li, Denis Furling, Onnik Agbulut, Arnaud Ferr. Treadmill running and mechanical overloading improved the strength of the plantaris muscle in the dystrophin-desmin double knockout (DKO) mouse. The Journal of physiology. 2024-07-09. PMID:38980963. |
in dko mice lacking both dystrophin and desmin, characterized by severe lower leg muscle weakness, atrophy and fragility in comparison to the less severe dmd mdx model, we found that enforced treadmill running improved absolute maximal force of the plantaris muscle, while that of tibialis anterior muscle remained unaffected by both enforced treadmill and voluntary wheel running. |
2024-07-09 |
2024-07-12 |
mouse |
| Jae-Sung You, Kate Karaman, Adriana Reyes-Ordoñez, Soohyun Lee, Yongdeok Kim, Rashid Bashir, Jie Che. Leucyl-tRNA Synthetase Contributes to Muscle Weakness through Mammalian Target of Rapamycin Complex 1 Activation and Autophagy Suppression in a Mouse Model of Duchenne Muscular Dystrophy. The American journal of pathology. 2024-05-25. PMID:38762116. |
duchenne muscular dystrophy (dmd), caused by loss-of-function mutations in the dystrophin gene, results in progressive muscle weakness and early fatality. |
2024-05-25 |
2024-05-27 |
mouse |
| Jae-Sung You, Kate Karaman, Adriana Reyes-Ordoñez, Soohyun Lee, Yongdeok Kim, Rashid Bashir, Jie Che. Leucyl-tRNA Synthetase Contributes to Muscle Weakness through Mammalian Target of Rapamycin Complex 1 Activation and Autophagy Suppression in a Mouse Model of Duchenne Muscular Dystrophy. The American journal of pathology. 2024-05-25. PMID:38762116. |
mammalian target of rapamycin complex 1 (mtorc1) is found to be hyperactive in the dmd muscles, accompanying muscle weakness and autophagy impairment. |
2024-05-25 |
2024-05-27 |
mouse |
| Angela L Roger, Debolina D Biswas, Meredith L Huston, Davina Le, Aidan M Bailey, Logan A Pucci, Yihan Shi, Jacqueline Robinson-Hamm, Charles A Gersbach, Mai K ElMalla. Respiratory Characterization of a Humanized Duchenne Muscular Dystrophy Mouse Model. Respiratory physiology & neurobiology. 2024-05-23. PMID:38782084. |
boys with dmd have progressive muscle weakness within the diaphragm that results in respiratory failure in the 2 |
2024-05-23 |
2024-05-27 |
mouse |
| Alessia De Masi, Nadège Zanou, Keno Strotjohann, Dohyun Lee, Tanes I Lima, Xiaoxu Li, Jongsu Jeon, Nicolas Place, Hoe-Yune Jung, Johan Auwer. Cyclo His-Pro Attenuates Muscle Degeneration in Murine Myopathy Models. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2024-05-10. PMID:38728626. |
although characterized by different pathological mechanisms, dmd and sarcopenia share the development of progressive muscle weakness and tissue inflammation. |
2024-05-10 |
2024-05-27 |
mouse |
| Emily Freeman, Stéphanie Langlois, Marcos F Leyba, Tarek Ammar, Zacharie Léger, Hugh J McMillan, Jean-Marc Renaud, Bernard J Jasmin, Kyle N Cowa. Pannexin 1 dysregulation in Duchenne muscular dystrophy and its exacerbation of dystrophic features in mdx mice. Skeletal muscle. vol 14. issue 1. 2024-04-27. PMID:38671506. |
duchenne muscular dystrophy (dmd) is associated with impaired muscle regeneration, progressive muscle weakness, damage, and wasting. |
2024-04-27 |
2024-04-29 |
mouse |
| Craig M Zaidman, Natalie L Goedeker, Amal A Aqul, Russell J Butterfield, Anne M Connolly, Ronald G Crystal, Kara E Godwin, Kan N Hor, Katherine D Mathews, Crystal M Proud, Elizabeth Kula Smyth, Aravindhan Veerapandiyan, Paul B Watkins, Jerry R Mendel. Management of Select Adverse Events Following Delandistrogene Moxeparvovec Gene Therapy for Patients With Duchenne Muscular Dystrophy. Journal of neuromuscular diseases. 2024-04-12. PMID:38607761. |
individuals living with dmd exhibit progressive muscle weakness resulting in loss of ambulation and limb function, respiratory insufficiency, and cardiomyopathy, with multiorgan involvement. |
2024-04-12 |
2024-04-15 |
Not clear |
| Akiko Wakisaka, Koichi Kimura, Hiroyuki Morita, Koki Nakanishi, Masao Daimon, Masanori Nojima, Hideki Itoh, Atsuhito Takeda, Ruriko Kitao, Tomihiro Imai, Tetsuhiko Ikeda, Takashi Nakajima, Chigusa Watanabe, Toshihiro Furukawa, Ichiro Ohno, Chiho Ishida, Norihiko Takeda, Kiyonobu Koma. Efficacy and Tolerability of Ivabradine for Cardiomyopathy in Patients with Duchenne Muscular Dystrophy. International heart journal. vol 65. issue 2. 2024-03-31. PMID:38556332. |
patients with dmd suffer from progressive muscle weakness, inevitable cardiomyopathy, increased heart rate (hr), and decreased blood pressure (bp). |
2024-03-31 |
2024-04-03 |
Not clear |
| Hiroyuki Awano, Yoshinori Nambu, Chieko Itoh, Akihiro Kida, Tetsushi Yamamoto, Tomoko Lee, Yasuhiro Takeshima, Kandai Nozu, Masafumi Matsu. Longitudinal data of serum creatine kinase levels and motor, pulmonary, and cardiac functions in 337 patients with Duchenne muscular dystrophy. Muscle & nerve. 2024-03-21. PMID:38511270. |
duchenne muscular dystrophy (dmd) presents with skeletal muscle weakness, followed by cardiorespiratory involvement. |
2024-03-21 |
2024-03-23 |
Not clear |
| Kadalraja Raghavan, Thanasekar Sivakumar, Koji Ichiyama, Naoki Yamamoto, Mangaleswaran Balamurugan, Vidyasagar Devaprasad Dedeepiya, Rajappa Senthilkumar, Senthilkumar Preethy, Samuel Jk Abraha. Efficacy of N-163 beta-glucan in beneficially improving biomarkers of relevance to muscle function in patients with muscular dystrophies in a pilot clinical study. Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology. vol 42. issue 4. 2024-02-26. PMID:38406382. |
muscular dystrophies other than duchenne muscular dystrophy (dmd) are genetic diseases characterized by increasing muscle weakness, loss of ambulation, and ultimately cardiac and respiratory failure. |
2024-02-26 |
2024-02-28 |
Not clear |
| Suzanne J Filius, Jaap Harlaar, Lonneke Alberts, Saskia Houwen-van Opstal, Herman van der Kooij, Mariska Mhp Jansse. Design requirements of upper extremity supports for daily use in Duchenne muscular dystrophy with severe muscle weakness. Journal of rehabilitation and assistive technologies engineering. vol 11. 2024-02-13. PMID:38344392. |
especially for severe muscle weakness (dmd ≥ brooke scale 4), the design of such arm support is challenging. |
2024-02-13 |
2024-02-15 |
Not clear |
| Monia Souidi, Jessica Resta, Haikel Dridi, Yvonne Sleiman, Steve Reiken, Karina Formoso, Sarah Colombani, Pascal Amédro, Pierre Meyer, Azzouz Charrabi, Marie Vincenti, Yang Liu, Rajesh Kumar Soni, Frank Lezoualc'h, D V M Stéphane Blot, François Rivier, Olivier Cazorla, Angelo Parini, Andrew R Marks, Jeanne Mialet-Perez, Alain Lacampagne, Albano C Mel. Ryanodine receptor dysfunction causes senescence and fibrosis in Duchenne dilated cardiomyopathy. Journal of cachexia, sarcopenia and muscle. 2024-01-14. PMID:38221511. |
duchenne muscular dystrophy (dmd) is an x-linked disorder characterized by progressive muscle weakness due to the absence of functional dystrophin. |
2024-01-14 |
2024-01-17 |
mouse |
| Andrea Hernández-Sánchez, Lidia Parra-Sánchez, Marisol Montolio, Lola Rueda-Ruzafa, Lucía Ortiz-Comino, María Del Mar Sánchez-Joy. Family Involvement and at-Home Physical Therapy on Duchenne Muscular Dystrophy: A Randomized Controlled Trial. Pediatric neurology. vol 152. 2024-01-07. PMID:38184986. |
duchenne muscular dystrophy (dmd) is a genetic condition that causes muscle weakness and begins in early childhood. |
2024-01-07 |
2024-01-10 |
Not clear |
| Abdelbaset Mohamed Elasbali, Waleed Abu Al-Soud, Mohd Adnan, Hassan H Alhassan, Taj Mohammad, Md Imtaiyaz Hassa. Discovering Promising Biomarkers and Therapeutic Targets for Duchenne Muscular Dystrophy: a Multiomics Meta-Analysis Approach. Molecular neurobiology. 2024-01-02. PMID:38165583. |
duchenne muscular dystrophy (dmd) is a genetic disorder that causes muscle weakness and degeneration. |
2024-01-02 |
2024-01-10 |
Not clear |
| Giorgia Coratti, Marika Pane, Claudia Brogna, Adele D'Amico, Elena Pegoraro, Luca Bello, Valeria A Sansone, Emilio Albamonte, Elisabetta Ferraroli, Elena Stacy Mazzone, Lavinia Fanelli, Sonia Messina, Maria Sframeli, Michela Catteruccia, Gianpaolo Cicala, Anna Capasso, Martina Ricci, Silvia Frosini, Giacomo De Luca, Enrica Rolle, Roberto De Sanctis, Nicola Forcina, Giulia Norcia, Luigia Passamano, Marianna Scutifero, Alice Gardani, Antonella Pini, Giulia Monaco, Maria Grazia D'Angelo, Daniela Leone, Riccardo Zanin, Gian Luca Vita, Chiara Panicucci, Claudio Bruno, Tiziana Mongini, Federica Ricci, Angela Berardinelli, Roberta Battini, Riccardo Masson, Giovanni Baranello, Claudia Dosi, Enrico Bertini, Vincenzo Nigro, Luisa Politano, Eugenio Mercur. Gain and loss of upper limb abilities in Duchenne muscular dystrophy patients: A 24-month study. Neuromuscular disorders : NMD. vol 34. 2023-12-29. PMID:38157655. |
duchenne muscular dystrophy (dmd) is a neuromuscular condition characterized by muscle weakness. |
2023-12-29 |
2024-01-05 |
Not clear |
| Victoria Brown, Elizabeth Merikle, Kelly Johnston, Katherine Gooch, Ivana Audhya, Linda Lowe. A qualitative study to understand the Duchenne muscular dystrophy experience from the parent/patient perspective. Journal of patient-reported outcomes. vol 7. issue 1. 2023-12-12. PMID:38085412. |
duchenne muscular dystrophy (dmd) is a rare, severe, fatal neuromuscular disease characterized by progressive atrophy and muscle weakness, resulting in loss of ambulation, decreased upper body function, and impaired cardiorespiratory function. |
2023-12-12 |
2023-12-17 |
Not clear |
| Kuan-Wen Wu, Cheng-Hao Yu, Tse-Hua Huang, Shiuan-Huei Lu, Yu-Lin Tsai, Ting-Ming Wang, Tung-Wu L. Children with Duchenne muscular dystrophy display specific kinematic strategies during obstacle-crossing. Scientific reports. vol 13. issue 1. 2023-10-10. PMID:37816796. |
duchenne muscular dystrophy (dmd) is a genetic disease characterized by progressive muscle weakness with increased neuromechanical challenge and fall risks, especially during obstructed locomotion. |
2023-10-10 |
2023-10-15 |
Not clear |
| Kyriaki Kekou, Maria Svingou, Nikos Vogiatzakis, Evangelia Nitsa, Danai Veltra, Nikolaos M Marinakis, Faidon-Nikolaos Tilemis, Maria Tzetis, Anastasios Mitrakos, Charalambia Tsaroucha, Nicoletta Selenti, Giorgos-Konstantinos Papadimas, Constantinos Papadopoulos, Joanne Traeger-Synodinos, Hanns Lochmuller, Christalena Sofocleou. Retrospective analysis of persistent HyperCKemia with or without muscle weakness in a case series from Greece highlights vast heterogeneous DMD gene variants. Expert review of molecular diagnostics. 2023-09-27. PMID:37754746. |
retrospective analysis of persistent hyperckemia with or without muscle weakness in a case series from greece highlights vast heterogeneous dmd gene variants. |
2023-09-27 |
2023-10-07 |
Not clear |