| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gianna C Riccitelli, Deborah Pacifico, Mauro Manconi, Davide Sparasci, Rosaria Sacco, Claudio Gobbi, Chiara Zecc. Relationship between cognitive disturbances and sleep disorders in multiple sclerosis is modulated by psychiatric symptoms. Multiple sclerosis and related disorders. vol 64. 2022-06-19. PMID:35717899. |
multiple sclerosis (ms) patients with cognitive impairment (ci) frequently suffer from sleep disturbances and emotional symptoms. |
2022-06-19 |
2023-08-14 |
Not clear |
| Wan Yu Hsu, Yael Goverover, Riley M Bov. Capturing cognitive changes in multiple sclerosis by performance-based functional and virtual reality assessments. Annals of physical and rehabilitation medicine. 2022-06-06. PMID:35667625. |
cognitive impairment (ci) has been recognized as one of the core multiple sclerosis (ms) symptoms that profoundly impact lives of people with ms (pwms). |
2022-06-06 |
2023-08-14 |
Not clear |
| Emilio Portaccio, Angelo Bellinvia, Lorenzo Razzolini, Luisa Pastò, Benedetta Goretti, Claudia Niccolai, Mattia Fonderico, Mauro Zaffaroni, Lorena Pippolo, Lucia Moiola, Monica Falautano, Claudia Celico, Rossella Viterbo, Francesco Patti, Clara Chisari, Paolo Gallo, Alice Riccardi, Martina Borghi, Antonio Bertolotto, Marta Simone, Carlo Pozzilli, Valentina Bianchi, Marco Roscio, Vittorio Martinelli, Giancarlo Comi, Massimo Filippi, Maria Trojano, Angelo Ghezzi, Maria Pia Amat. Long-term Cognitive Outcomes and Socioprofessional Attainment in People With Multiple Sclerosis With Childhood Onset. Neurology. vol 98. issue 16. 2022-04-19. PMID:35437271. |
patients with pediatric-onset multiple sclerosis (ms) can be especially vulnerable to cognitive impairment (ci) due to the onset of ms during a critical period for cns development and maturation. |
2022-04-19 |
2023-08-13 |
Not clear |
| Yen-Hui Liao, Chien-Tai Hong, Tsai-Wei Huan. Botulinum Toxin for Essential Tremor and Hands Tremor in the Neurological Diseases: A Meta-Analysis of Randomized Controlled Trials. Toxins. vol 14. issue 3. 2022-03-24. PMID:35324700. |
bont significantly attenuated hand tremor severity in patients with either essential tremor (et), parkinson's disease or multiple sclerosis (standardized mean difference [smd] = -0.59, 95% confidence interval [ci], -0.95 to -0.24, |
2022-03-24 |
2023-08-13 |
Not clear |
| Hengameh Shams, Xiaorong Shao, Adam Santaniello, Gina Kirkish, Adil Harroud, Qin Ma, Noriko Isobe, Catherine Schaefer, Jacob L McCauley, Bruce A C Cree, Alessandro Didonna, Sergio E Baranzini, Nikolaos A Patsopoulos, Stephen L Hauser, Lisa F Barcellos, Roland G Henry, Jorge R Oksenber. Polygenic risk score association with multiple sclerosis susceptibility and phenotype in Europeans. Brain : a journal of neurology. 2022-03-07. PMID:35253861. |
the largest genome-wide association dataset for multiple sclerosis to date (n = 41,505) was leveraged to generate prs scores, serving as an informative susceptibility marker, tested in two independent datasets, uk biobank [ukbb, area under the curve (auc) = 0.73, 95% ci: 0.72-0.74, p = 6.41e-146] and kaiser permanente in northern california (kpnc, auc = 0.8, 95% ci: 0.76-0.82, p = 1.5e-53). |
2022-03-07 |
2023-08-13 |
Not clear |
| Eleonora Virgilio, Domizia Vecchio, Ilaria Crespi, Chiara Puricelli, Paolo Barbero, Giulia Galli, Roberto Cantello, Umberto Dianzani, Cristoforo Com. Cerebrospinal fluid biomarkers and cognitive functions at multiple sclerosis diagnosis. Journal of neurology. 2022-01-28. PMID:35088141. |
cognitive impairment (ci) is a frequent and disabling symptom in multiple sclerosis (ms). |
2022-01-28 |
2023-08-13 |
Not clear |
| Haoxin Peng, Xiangrong Wu, Yaokai Wen, Jinsheng Lin, Wenhui Gua. Myocardial infarction and stroke risks in multiple sclerosis patients: A two-sample Mendelian randomization study. Multiple sclerosis and related disorders. vol 58. 2022-01-23. PMID:35066269. |
using two-sample mendelian randomization (mr) analysis with genetic data from large-scale genome-wide association studies (international multiple sclerosis genetics consortium containing 14,498 ms cases, coronary artery disease genome wide replication and meta-analysis plus the coronary artery disease genetics consortium containing 43,676 mi cases and 40,585 stroke cases), we found that ms was causally associated with an increased risk of mi (or = 1.03; 95%ci 1.00-1.06; p = 0.0243), directionally consistent in the weighted median, mr-egger, and the mr-presso methods. |
2022-01-23 |
2023-08-13 |
Not clear |
| Wan-Yu Hsu, William Rowles, Joaquin A Anguera, Annika Anderson, Jessica W Younger, Samuel Friedman, Adam Gazzaley, Riley Bov. Assessing Cognitive Function in Multiple Sclerosis With Digital Tools: Observational Study. Journal of medical Internet research. vol 23. issue 12. 2021-12-30. PMID:34967751. |
cognitive impairment (ci) is one of the most prevalent symptoms of multiple sclerosis (ms). |
2021-12-30 |
2023-08-13 |
Not clear |
| Oksana O Kopchak, Tetiana A Odintsova, Oleksandr R Puly. COGNITIVE FUNCTIONS IN MULTIPLE SCLEROSIS PATIENTS DEPENDING ON THE DIFFERENT RISK FACTORS PRESENCE. Wiadomosci lekarskie (Warsaw, Poland : 1960). vol 74. issue 10 pt 1. 2021-12-13. PMID:34897002. |
the aim: to clarify the influence of different risk factors on cognitive impairment (ci) in general and in separate domains and their association with mri findings in patients with relapsing-remitting (rrms) and progressive forms of multiple sclerosis (spms and ppms). |
2021-12-13 |
2023-08-13 |
Not clear |
| Ruth Schneider, Britta Matusche, Erhan Genç, Ralf Gold, Barbara Bellenberg, Carsten Luka. Microstructural White Matter Alterations in Cognitively Impaired Patients at Early Stages of Multiple Sclerosis. Clinical neuroradiology. vol 31. issue 4. 2021-12-11. PMID:33787958. |
as conventional quantitative magnetic resonance imaging (mri) parameters are weakly associated with cognitive impairment (ci) in early multiple sclerosis (ms), we explored microstructural white matter alterations in early ms or clinically isolated syndrome (cis) comparing patients with or without ci. |
2021-12-11 |
2023-08-13 |
Not clear |
| Massimiliano Di Filippo, Andrea Mancini, Laura Bellingacci, Lorenzo Gaetani, Petra Mazzocchetti, Teresa Zelante, Livia La Barbera, Antonella De Luca, Michela Tantucci, Alessandro Tozzi, Valentina Durante, Miriam Sciaccaluga, Alfredo Megaro, Davide Chiasserini, Nicola Salvadori, Viviana Lisetti, Emilio Portaccio, Cinzia Costa, Paola Sarchielli, Maria Pia Amato, Lucilla Parnetti, Maria Teresa Viscomi, Luigina Romani, Paolo Calabres. Interleukin-17 affects synaptic plasticity and cognition in an experimental model of multiple sclerosis. Cell reports. vol 37. issue 10. 2021-12-08. PMID:34879272. |
cognitive impairment (ci) is a disabling concomitant of multiple sclerosis (ms) with a complex and controversial pathogenesis. |
2021-12-08 |
2023-08-13 |
mouse |
| Virginia Meca-Lallana, Francisco Gascón-Giménez, Ricardo C Ginestal-López, Yolanda Higueras, Nieves Téllez-Lara, Joan Carreres-Polo, Sara Eichau-Madueño, Jesús Romero-Imbroda, Ángela Vidal-Jordana, Francisco Pérez-Miralle. Cognitive impairment in multiple sclerosis: diagnosis and monitoring. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 42. issue 12. 2021-12-06. PMID:33796947. |
cognitive impairment (ci) has a prevalence of 45-70% in people with multiple sclerosis (ms), producing a negative impact on their quality of life, personal life, and work. |
2021-12-06 |
2023-08-13 |
Not clear |
| Elisabet Lopez-Soley, Eloy Martinez-Heras, Magi Andorra, Aleix Solanes, Joaquim Radua, Carmen Montejo, Salut Alba-Arbalat, Nuria Sola-Valls, Irene Pulido-Valdeolivas, Maria Sepulveda, Lucia Romero-Pinel, Elvira Munteis, Jose E Martínez-Rodríguez, Yolanda Blanco, Elena H Martinez-Lapiscina, Pablo Villoslada, Albert Saiz, Elisabeth Solana, Sara Llufri. Dynamics and Predictors of Cognitive Impairment along the Disease Course in Multiple Sclerosis. Journal of personalized medicine. vol 11. issue 11. 2021-11-30. PMID:34834459. |
(1) background: the evolution and predictors of cognitive impairment (ci) in multiple sclerosis (ms) are poorly understood. |
2021-11-30 |
2023-08-13 |
Not clear |
| M S Kozin, I S Kiselev, N M Baulina, G V Pavlova, A N Boyko, O G Kulakova, O O Favorov. [Risk of Multiple Sclerosis: Analysis of Interactions Between Variants of Nuclear and Mitochondrial Genomes]. Molekuliarnaia biologiia. vol 55. issue 6. 2021-11-30. PMID:34837699. |
two mitonuclear combinations associated with multiple sclerosis were identified: the ucp2 (rs660339)*a + mt-atp6 (rs193303045)*g combination was characterized by p-value = 0.015 and or= 1.39 [95% ci 1.05-1.87], and the pvt1 (rs2114358)*g + mt-nd1 (rs1599988)*С combination - by p-value = 0.012 and or = 1.77 [95% ci 1.10-2.84]. |
2021-11-30 |
2023-08-13 |
human |
| M S Kozin, I S Kiselev, N M Baulina, G V Pavlova, A N Boyko, O G Kulakova, O O Favorov. [Risk of Multiple Sclerosis: Analysis of Interactions Between Variants of Nuclear and Mitochondrial Genomes]. Molekuliarnaia biologiia. vol 55. issue 6. 2021-11-30. PMID:34837699. |
only one of the individual components of these combinations, allele rs660339*a of the nuclear gene ucp2 encoding uncoupling protein 2 of the mitochondrial anion carrier family, was independently associated with multiple sclerosis (p = 0.028; or = 1.36 [95% ci 1.01-1.84]). |
2021-11-30 |
2023-08-13 |
human |
| S M Gomez-Moreno, M L Cuadrado, I Cruz-Orduña, E M Martínez-Acebes, R Gordo-Mañas, C Fernández-Pérez, R García-Ramo. Validation of the Spanish-language version of the Montreal Cognitive Assessment as a screening test for cognitive impairment in multiple sclerosis. Neurologia (Barcelona, Spain). 2021-11-27. PMID:34836843. |
the neuropsychological batteries traditionally used for the assessment of cognitive impairment (ci) in patients with multiple sclerosis are complex tests requiring a long time to administer. |
2021-11-27 |
2023-08-13 |
Not clear |
| F Nelson, J Steinber. Feasibility and Findings from a Novel Working Memory fMRI Paradigm in Multiple Sclerosis. Journal of neurological disorders & stroke. vol 1. issue 2. 2021-10-21. PMID:24772453. |
functional mri (fmri) basic cognitive paradigms such as the n-back have been shown to detect cognitive impairment (ci) in multiple sclerosis (ms). |
2021-10-21 |
2023-08-13 |
Not clear |
| Marta Altieri, Mariangela Fratino, Ilaria Maestrini, Claudia Dionisi, Rosanna Annecca, Edoardo Vicenzini, Vittorio Di Pier. Cognitive Performance in Relapsing-Remitting Multiple Sclerosis: At Risk or Impaired? Dementia and geriatric cognitive disorders. vol 49. issue 6. 2021-10-20. PMID:33735893. |
since cognitive impairment (ci) occurs on average in 45% of multiple sclerosis (ms) patients, the early detection of patients "at risk" of ci is important in order to promptly apply preventive strategies. |
2021-10-20 |
2023-08-13 |
Not clear |
| Marta Altieri, Mariangela Fratino, Ilaria Maestrini, Claudia Dionisi, Rosanna Annecca, Edoardo Vicenzini, Vittorio Di Pier. Cognitive Performance in Relapsing-Remitting Multiple Sclerosis: At Risk or Impaired? Dementia and geriatric cognitive disorders. vol 49. issue 6. 2021-10-20. PMID:33735893. |
the aim of the present study was to investigate the prevalence and risk factors for ci in ms patients using the brief international cognitive assessment for multiple sclerosis (bicams) as a screening test. |
2021-10-20 |
2023-08-13 |
Not clear |
| Nuala McNicholas, Niall Tubridy, Michael Hutchinson, Chris McGuiga. Perceived and objective cognitive impairment in newly diagnosed versus established multiple sclerosis: impact of disease duration. Irish journal of medical science. vol 190. issue 3. 2021-10-04. PMID:33108620. |
cognitive impairment (ci) is common in multiple sclerosis (ms), including newly diagnosed ms, where it is particularly underrecognised. |
2021-10-04 |
2023-08-13 |
Not clear |