All Relations between Hyperprolactinemia and dopamine
Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
G Nicholson, G H Greeley, J Humm, W W Youngblood, J S Kize. Prolactin in cerebrospinal fluid: a probable site of prolactin autoregulation. Brain research. vol 190. issue 2. 1980-07-28. PMID:6102886. |
in the median eminence, but not the medial preoptic area, parallel increases in the activity of tyrosine hydroxylase and the turnover of dopamine (but not norepinephrine) occurred following hyperprolactinemia. |
1980-07-28 |
2023-08-12 |
rat |
W S Evans, A D Rogol, R M MacLeod, M O Thorne. Dopaminergic mechanisms and luteinizing hormone secretion. I. Acute administration of the dopamine agonist bromocriptine does not inhibit luteinizing hormone release in hyperprolactinemic women. The Journal of clinical endocrinology and metabolism. vol 50. issue 1. 1980-02-26. PMID:7188612. |
since hyperprolactinemia is associated with increased hypothalamic dopamine turnover (which may reflect increased dopaminergic activity), inhibition of gnrh by dopamine in this situation would be maximal. |
1980-02-26 |
2023-08-12 |
Not clear |
S A Fine, L A Frohma. Loss of central nervous system component of dopaminergic inhibition of prolactin secretion in patients with prolactin-secreting pituitary tumors. The Journal of clinical investigation. vol 61. issue 4. 1978-08-14. PMID:659585. |
the administration of l-dopa suppresses prolactin (prl) secretion in normal subjects and in patients with hyperprolactinemia, although it is not known whether this effect, which requires the conversion of dopa to dopamine, is mediated peripherally or through the central nervous system. |
1978-08-14 |
2023-08-11 |
human |
H Leblanc, G C Lachelin, S Abu-Fadil, S S Ye. Effects of dopamine infusion on pituitary hormone secretion in humans. The Journal of clinical endocrinology and metabolism. vol 43. issue 3. 1976-11-01. PMID:956350. |
dopamine, infused at a rate of 4 mug/kg/min for 3-4 h unaccompanied by any significant changes in cardiovascular dynamics, induced a prompt and sustained suppression of circulating prolactin (prl) levels in normal men and women as well as in patients with hyperprolactinemia. |
1976-11-01 |
2023-08-11 |
human |