| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jennifer L Whitwell, Stephen D Weigand, Bradley F Boeve, Matthew L Senjem, Jeffrey L Gunter, Mariely DeJesus-Hernandez, Nicola J Rutherford, Matthew Baker, David S Knopman, Zbigniew K Wszolek, Joseph E Parisi, Dennis W Dickson, Ronald C Petersen, Rosa Rademakers, Clifford R Jack, Keith A Joseph. Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics. Brain : a journal of neurology. vol 135. issue Pt 3. 2012-04-09. PMID:22366795. |
we aimed to determine the regional pattern of brain atrophy associated with the c9orf72 gene mutation, and to determine which regions best differentiate c9orf72 from subjects with mutations in tau and progranulin, and from sporadic frontotemporal dementia. |
2012-04-09 |
2023-08-12 |
human |
| Jennifer L Whitwell, Stephen D Weigand, Bradley F Boeve, Matthew L Senjem, Jeffrey L Gunter, Mariely DeJesus-Hernandez, Nicola J Rutherford, Matthew Baker, David S Knopman, Zbigniew K Wszolek, Joseph E Parisi, Dennis W Dickson, Ronald C Petersen, Rosa Rademakers, Clifford R Jack, Keith A Joseph. Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics. Brain : a journal of neurology. vol 135. issue Pt 3. 2012-04-09. PMID:22366795. |
a total of 76 subjects, including 56 with a clinical diagnosis of behavioural variant frontotemporal dementia and a mutation in one of these genes (19 with c9orf72 mutations, 25 with tau mutations and 12 with progranulin mutations) and 20 sporadic subjects with behavioural variant frontotemporal dementia (including 50% with amyotrophic lateral sclerosis), with magnetic resonance imaging were included in this study. |
2012-04-09 |
2023-08-12 |
human |
| Jennifer L Whitwell, Stephen D Weigand, Bradley F Boeve, Matthew L Senjem, Jeffrey L Gunter, Mariely DeJesus-Hernandez, Nicola J Rutherford, Matthew Baker, David S Knopman, Zbigniew K Wszolek, Joseph E Parisi, Dennis W Dickson, Ronald C Petersen, Rosa Rademakers, Clifford R Jack, Keith A Joseph. Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics. Brain : a journal of neurology. vol 135. issue Pt 3. 2012-04-09. PMID:22366795. |
patterns of atrophy therefore differed across subjects with c9orf72, tau and progranulin mutations and sporadic frontotemporal dementia. |
2012-04-09 |
2023-08-12 |
human |
| Heather Woo. A hexanucleotide repeat expansion in C9ORF72 links amyotrophic lateral sclerosis and frontotemporal dementia. Nature reviews. Neurology. vol 7. issue 11. 2012-02-21. PMID:22009283. |
a hexanucleotide repeat expansion in c9orf72 links amyotrophic lateral sclerosis and frontotemporal dementia. |
2012-02-21 |
2023-08-12 |
Not clear |