| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C-C Tzeng, L-P Tsai, Y-K Chang, Y-J Hung, Y-Y Chang, Y-P Su, J-J Jiang, H-M Lian. A 15-year-long Southern blotting analysis of FMR1 to detect female carriers and for prenatal diagnosis of fragile X syndrome in Taiwan. Clinical genetics. vol 92. issue 2. 2018-04-18. PMID:28139839. |
a 15-year-long southern blotting analysis of fmr1 to detect female carriers and for prenatal diagnosis of fragile x syndrome in taiwan. |
2018-04-18 |
2023-08-13 |
Not clear |
| Indhu-Shree Rajan-Babu, Mulias Lian, Felicia S H Cheah, Min Chen, Arnold S C Tan, Ethiraj B Prasath, Seong Feei Loh, Samuel S Chon. FMR1 CGG repeat expansion mutation detection and linked haplotype analysis for reliable and accurate preimplantation genetic diagnosis of fragile X syndrome. Expert reviews in molecular medicine. vol 19. 2018-04-06. PMID:28720156. |
fmr1 cgg repeat expansion mutation detection and linked haplotype analysis for reliable and accurate preimplantation genetic diagnosis of fragile x syndrome. |
2018-04-06 |
2023-08-13 |
Not clear |
| Indhu-Shree Rajan-Babu, Mulias Lian, Felicia S H Cheah, Min Chen, Arnold S C Tan, Ethiraj B Prasath, Seong Feei Loh, Samuel S Chon. FMR1 CGG repeat expansion mutation detection and linked haplotype analysis for reliable and accurate preimplantation genetic diagnosis of fragile X syndrome. Expert reviews in molecular medicine. vol 19. 2018-04-06. PMID:28720156. |
fragile x mental retardation 1 (fmr1) full-mutation expansion causes fragile x syndrome. |
2018-04-06 |
2023-08-13 |
Not clear |
| Akira Nagaoka, Hiroaki Takehara, Akiko Hayashi-Takagi, Jun Noguchi, Kazuhiko Ishii, Fukutoshi Shirai, Sho Yagishita, Takanori Akagi, Takanori Ichiki, Haruo Kasa. Abnormal intrinsic dynamics of dendritic spines in a fragile X syndrome mouse model in vivo. Scientific reports. vol 6. 2018-04-02. PMID:27221801. |
this was achieved using a microfluidic brain interface and open-dura surgery, with the goal of abolishing neuronal ca(2+) signaling in the visual cortex of wild-type mice and rodent models of fragile x syndrome (fmr1 knockout [ko]). |
2018-04-02 |
2023-08-13 |
mouse |
| Rustam Esanov, Nadja S Andrade, Sarah Bennison, Claes Wahlestedt, Zane Zeie. The FMR1 promoter is selectively hydroxymethylated in primary neurons of fragile X syndrome patients. Human molecular genetics. vol 25. issue 22. 2018-02-13. PMID:28173181. |
the fmr1 promoter is selectively hydroxymethylated in primary neurons of fragile x syndrome patients. |
2018-02-13 |
2023-08-13 |
Not clear |
| Rustam Esanov, Nadja S Andrade, Sarah Bennison, Claes Wahlestedt, Zane Zeie. The FMR1 promoter is selectively hydroxymethylated in primary neurons of fragile X syndrome patients. Human molecular genetics. vol 25. issue 22. 2018-02-13. PMID:28173181. |
fragile x syndrome (fxs) results from a repeat expansion mutation near the fmr1 gene promoter and is the most common form of heritable intellectual disability and autism. |
2018-02-13 |
2023-08-13 |
Not clear |
| Konrad Juczewski, Helen von Richthofen, Claudia Bagni, Tansu Celikel, Gilberto Fisone, Patrik Kriege. Somatosensory map expansion and altered processing of tactile inputs in a mouse model of fragile X syndrome. Neurobiology of disease. vol 96. 2018-02-09. PMID:27616423. |
fragile x syndrome (fxs) is a common inherited form of intellectual disability caused by the absence or reduction of the fragile x mental retardation protein (fmrp) encoded by the fmr1 gene. |
2018-02-09 |
2023-08-13 |
mouse |
| Russell L Hutson, Rachel L Thompson, Andrew P Bantel, Charles R Tessie. Acamprosate rescues neuronal defects in the Drosophila model of Fragile X Syndrome. Life sciences. vol 195. 2018-02-08. PMID:29317220. |
several off-label studies have shown that acamprosate can provide some clinical benefits in youth with fragile x syndrome (fxs), an autism spectrum disorder caused by loss of function of the highly conserved fmr1 gene. |
2018-02-08 |
2023-08-13 |
drosophila_melanogaster |
| Yao-Ju Wu, Mao-Ting Hsu, Ming-Chong Ng, Tamara G Amstislavskaya, Maria A Tikhonova, Yi-Ling Yang, Kwok-Tung L. Fragile X Mental Retardation-1 Knockout Zebrafish Shows Precocious Development in Social Behavior. Zebrafish. vol 14. issue 5. 2018-01-18. PMID:28829283. |
fragile x syndrome (fxs) is a generally hereditary form of human mental retardation that is caused by triplet repeat expansion (cgg) mutation in fragile x mental retardation 1 (fmr1) gene promoter and that results in the absence of the fragile x mental retardation protein (fmrp) expression. |
2018-01-18 |
2023-08-13 |
human |
| Conner D Reynolds, Suzanne O Nolan, Taylor Jefferson, Joaquin N Lug. Sex-specific and genotype-specific differences in vocalization development in FMR1 knockout mice. Neuroreport. vol 27. issue 18. 2018-01-10. PMID:27824730. |
fragile x syndrome is a neurodevelopmental disorder caused by a trinucleotide (cgg) hyperexpansion in the fmr1 gene, functionally silencing transcription of the fragile x mental retardation protein (fmrp). |
2018-01-10 |
2023-08-13 |
mouse |
| Madhumita Roy Chowdhury, Sandeepa Chauhan, Anjali Dabral, B K Thelma, Neerja Gupta, Madhulika Kabr. Validation of Polymerase Chain Reaction-Based Assay to Detect Actual Number of CGG Repeats in FMR1 Gene in Indian Fragile X Syndrome Patients. Journal of child neurology. vol 32. issue 4. 2018-01-02. PMID:28193118. |
validation of polymerase chain reaction-based assay to detect actual number of cgg repeats in fmr1 gene in indian fragile x syndrome patients. |
2018-01-02 |
2023-08-13 |
Not clear |
| Valerie Lemaire-Mayo, Enejda Subashi, Nadia Henkous, Daniel Beracochea, Susanna Pietropaol. Behavioral effects of chronic stress in the Fmr1 mouse model for fragile X syndrome. Behavioural brain research. vol 320. 2017-12-26. PMID:27939692. |
behavioral effects of chronic stress in the fmr1 mouse model for fragile x syndrome. |
2017-12-26 |
2023-08-13 |
mouse |
| Valerie Lemaire-Mayo, Enejda Subashi, Nadia Henkous, Daniel Beracochea, Susanna Pietropaol. Behavioral effects of chronic stress in the Fmr1 mouse model for fragile X syndrome. Behavioural brain research. vol 320. 2017-12-26. PMID:27939692. |
fragile x syndrome (fxs) is a pervasive developmental disorder due to a mutation in the fmr1 x-linked gene. |
2017-12-26 |
2023-08-13 |
mouse |
| Marta Pardo, Eleonore Beurel, Richard S Jop. Cotinine administration improves impaired cognition in the mouse model of Fragile X syndrome. The European journal of neuroscience. vol 45. issue 4. 2017-12-22. PMID:27775852. |
we tested if acute cotinine treatment is capable of improving cognition in the mouse model of fragile x syndrome, fmr1 |
2017-12-22 |
2023-08-13 |
mouse |
| Suk Yu Yau, Christine Chiu, Mariana Vetrici, Brian R Christi. Chronic minocycline treatment improves social recognition memory in adult male Fmr1 knockout mice. Behavioural brain research. vol 312. 2017-12-19. PMID:27291517. |
fragile x syndrome (fxs) is caused by a mutation in the fmr1 gene that leads to silencing of the gene and a loss of its gene product, fragile x mental retardation protein (fmrp). |
2017-12-19 |
2023-08-13 |
mouse |
| Samantha L Hodges, Suzanne O Nolan, Conner D Reynolds, Joaquin N Lug. Spectral and temporal properties of calls reveal deficits in ultrasonic vocalizations of adult Fmr1 knockout mice. Behavioural brain research. vol 332. 2017-12-19. PMID:28552599. |
the fmr1 knockout (ko) mouse has commonly been used to investigate communication impairments, one of the key diagnostic symptoms observed in fragile x syndrome (fxs) and autism spectrum disorder (asd). |
2017-12-19 |
2023-08-13 |
mouse |
| Kun Zhang, Yu-Jiao Li, Yanyan Guo, Kai-Yin Zheng, Qi Yang, Le Yang, Xin-Shang Wang, Qian Song, Tao Chen, Min Zhuo, Ming-Gao Zha. Elevated progranulin contributes to synaptic and learning deficit due to loss of fragile X mental retardation protein. Brain : a journal of neurology. vol 140. issue 12. 2017-12-13. PMID:29096020. |
fragile x syndrome is an inheritable form of intellectual disability caused by loss of fragile x mental retardation protein (fmrp, encoded by the fmr1 gene). |
2017-12-13 |
2023-08-13 |
mouse |
| Min Chen, Mingjue Zhao, Caroline G Lee, Samuel S Chon. Identification of microsatellite markers <1 Mb from the FMR1 CGG repeat and development of a single-tube tetradecaplex PCR panel of highly polymorphic markers for preimplantation genetic diagnosis of fragile X syndrome. Genetics in medicine : official journal of the American College of Medical Genetics. vol 18. issue 9. 2017-12-11. PMID:26741412. |
identification of microsatellite markers <1 mb from the fmr1 cgg repeat and development of a single-tube tetradecaplex pcr panel of highly polymorphic markers for preimplantation genetic diagnosis of fragile x syndrome. |
2017-12-11 |
2023-08-13 |
Not clear |
| Risa Kashima, Sougata Roy, Manuel Ascano, Veronica Martinez-Cerdeno, Jeanelle Ariza-Torres, Sunghwan Kim, Justin Louie, Yao Lu, Patricio Leyton, Kenneth D Bloch, Thomas B Kornberg, Paul J Hagerman, Randi Hagerman, Giorgio Lagna, Akiko Hat. Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome. Science signaling. vol 9. issue 431. 2017-11-29. PMID:27273096. |
epigenetic silencing of fragile x mental retardation 1 (fmr1) causes fragile x syndrome (fxs), a common inherited form of intellectual disability and autism. |
2017-11-29 |
2023-08-13 |
mouse |
| Urszula Brykczynska, Eline Pecho-Vrieseling, Anke Thiemeyer, Jessica Klein, Isabelle Fruh, Thierry Doll, Carole Manneville, Sascha Fuchs, Mariavittoria Iazeolla, Martin Beibel, Guglielmo Roma, Ulrike Naumann, Nicholas Kelley, Edward J Oakeley, Matthias Mueller, Baltazar Gomez-Mancilla, Marc Bühler, Elisabetta Tabolacci, Pietro Chiurazzi, Giovanni Neri, Tewis Bouwmeester, Francesco Paolo Di Giorgio, Barna D Fodo. CGG Repeat-Induced FMR1 Silencing Depends on the Expansion Size in Human iPSCs and Neurons Carrying Unmethylated Full Mutations. Stem cell reports. vol 7. issue 6. 2017-11-13. PMID:27840045. |
in fragile x syndrome (fxs), cgg repeat expansion greater than 200 triplets is believed to trigger fmr1 gene silencing and disease etiology. |
2017-11-13 |
2023-08-13 |
human |