| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kendall H Lee, Frederick L Hitti, Su-Youne Chang, Dongchul C Lee, David W Roberts, Cameron C McIntyre, James C Leite. High frequency stimulation abolishes thalamic network oscillations: an electrophysiological and computational analysis. Journal of neural engineering. vol 8. issue 4. 2011-11-23. PMID:21623007. |
deep brain stimulation (dbs) of the thalamus has been demonstrated to be effective for the treatment of epilepsy. |
2011-11-23 |
2023-08-12 |
Not clear |
| Paul R Gigante, Robert R Goodma. Alternative surgical approaches in epilepsy. Current neurology and neuroscience reports. vol 11. issue 4. 2011-10-24. PMID:21584657. |
recently published results from the sante (stimulation of the anterior nuclei of thalamus for epilepsy) trial-the first large-scale, randomized, double-blind trial of bilateral anterior thalamus dbs for mre-demonstrate a significant reduction in seizure frequency with programmed stimulation. |
2011-10-24 |
2023-08-12 |
Not clear |
| Xiao-Ling Zhong, Jin-Tai Yu, Qun Zhang, Nai-Dong Wang, Lan Ta. Deep brain stimulation for epilepsy in clinical practice and in animal models. Brain research bulletin. vol 85. issue 3-4. 2011-09-30. PMID:21457763. |
recently, a large and multicenter trial (sante: stimulation of the anterior nucleus of the thalamus for epilepsy) was conducted and subsequently with encouraging results, making ant the most well-established target for dbs in the treatment of epilepsy to date. |
2011-09-30 |
2023-08-12 |
Not clear |
| Zhiqiang Zhang, Guangming Lu, Yuan Zhong, Qifu Tan, Huafu Chen, Wei Liao, Lei Tian, Zhihao Li, Jixin Shi, Yijun Li. fMRI study of mesial temporal lobe epilepsy using amplitude of low-frequency fluctuation analysis. Human brain mapping. vol 31. issue 12. 2011-09-26. PMID:20225278. |
in the patients, the regions showing increased alff were consistently distributed in the mesial temporal lobe, thalamus, and a few of other cortical and subcortical structures composing a mesial temporal epilepsy network proposed previously, while the regions showing decreased alff were mostly located in the areas of so-called default-mode network. |
2011-09-26 |
2023-08-12 |
human |
| Ming Song, Hanjian Du, Nan Wu, Bing Hou, Guocai Wu, Jian Wang, Hua Feng, Tianzi Jian. Impaired resting-state functional integrations within default mode network of generalized tonic-clonic seizures epilepsy. PloS one. vol 6. issue 2. 2011-09-01. PMID:21364890. |
many recent studies have found that the ictal alterations in brain activity of the gtcs epilepsy patients are focally involved in some brain regions, including thalamus, upper brainstem, medial prefrontal cortex, posterior midbrain regions, and lateral parietal cortex. |
2011-09-01 |
2023-08-12 |
human |
| Carmen Rubio, Verónica Custodio, Edith González, Socorro Retana-Márquez, Marisol López, Carlos Pa. Effects of kainic acid lesions of the cerebellar interpositus and dentate nuclei on amygdaloid kindling in rats. Brain research bulletin. vol 85. issue 1-2. 2011-08-15. PMID:21335069. |
we hypothesize that the cerebellar effect on epilepsy drives skeletal motor responses, mainly in generalized seizures when the thalamus and neocortex are affected. |
2011-08-15 |
2023-08-12 |
rat |
| Naoki Akamatsu, Sadatoshi Tsuj. [Deep brain stimulation for epilepsy]. Brain and nerve = Shinkei kenkyu no shinpo. vol 63. issue 4. 2011-08-04. PMID:21441639. |
currently, the thalamus, subthalamic nucleus, hippocampus, cerebellar nuclei, and cortical seizure foci are stimulated for treating epilepsy. |
2011-08-04 |
2023-08-12 |
Not clear |
| Naoki Akamatsu, Sadatoshi Tsuj. [Deep brain stimulation for epilepsy]. Brain and nerve = Shinkei kenkyu no shinpo. vol 63. issue 4. 2011-08-04. PMID:21441639. |
this report documents a clinical trial involving stimulation of the anterior nucleus of the thalamus for epilepsy (sante). |
2011-08-04 |
2023-08-12 |
Not clear |
| Xiang-Qing Wang, Sen-Yang Lang, L U Hong, M A Lin, M A O Yan-Ling, Fei Yan. Changes in extrafrontal integrity and cognition in frontal lobe epilepsy: a diffusion tensor imaging study. Epilepsy & behavior : E&B. vol 20. issue 3. 2011-07-15. PMID:21296621. |
patients with fle also had decreased fa in the right frontal lobe that correlated with patient age at seizure onset and increased md in the left thalamus that correlated with duration of epilepsy. |
2011-07-15 |
2023-08-12 |
Not clear |
| Xiang-Qing Wang, Sen-Yang Lang, L U Hong, M A Lin, M A O Yan-Ling, Fei Yan. Changes in extrafrontal integrity and cognition in frontal lobe epilepsy: a diffusion tensor imaging study. Epilepsy & behavior : E&B. vol 20. issue 3. 2011-07-15. PMID:21296621. |
our results suggest that the thalamus might be an important extrafrontal structure involved in fle and that a longer duration of epilepsy might result in more abnormalities in the thalamus. |
2011-07-15 |
2023-08-12 |
Not clear |
| Jerzy P Szaflarski, Mark DiFrancesco, Thomas Hirschauer, Christi Banks, Michael D Privitera, Jean Gotman, Scott K Hollan. Cortical and subcortical contributions to absence seizure onset examined with EEG/fMRI. Epilepsy & behavior : E&B. vol 18. issue 4. 2010-12-02. PMID:20580319. |
the results of this study support our original hypothesis and indicate that in the patients with r-ige studied, absence seizures may be initiated by widespread cortical (frontal and parietal) areas and sustained in subcortical (thalamic) regions, suggesting that the examined patients have cortical onset epilepsy with propagation to thalamus. |
2010-12-02 |
2023-08-12 |
human |
| Simone Bittencourt, Francisco P Dubiela, Claudio Queiroz, Luciene Covolan, Danielle Andrade, Andres Lozano, Luiz E Mello, Clement Haman. Microinjection of GABAergic agents into the anterior nucleus of the thalamus modulates pilocarpine-induced seizures and status epilepticus. Seizure. vol 19. issue 4. 2010-07-09. PMID:20347349. |
the anterior nucleus of the thalamus (an) has been suggested as a potential target for seizure modulation in animal models and patients with refractory epilepsy. |
2010-07-09 |
2023-08-12 |
rat |
| Robert Fisher, Vicenta Salanova, Thomas Witt, Robert Worth, Thomas Henry, Robert Gross, Kalarickal Oommen, Ivan Osorio, Jules Nazzaro, Douglas Labar, Michael Kaplitt, Michael Sperling, Evan Sandok, John Neal, Adrian Handforth, John Stern, Antonio DeSalles, Steve Chung, Andrew Shetter, Donna Bergen, Roy Bakay, Jaimie Henderson, Jacqueline French, Gordon Baltuch, William Rosenfeld, Andrew Youkilis, William Marks, Paul Garcia, Nicolas Barbaro, Nathan Fountain, Carl Bazil, Robert Goodman, Guy McKhann, K Babu Krishnamurthy, Steven Papavassiliou, Charles Epstein, John Pollard, Lisa Tonder, Joan Grebin, Robert Coffey, Nina Grave. Electrical stimulation of the anterior nucleus of thalamus for treatment of refractory epilepsy. Epilepsia. vol 51. issue 5. 2010-06-29. PMID:20331461. |
we report a multicenter, double-blind, randomized trial of bilateral stimulation of the anterior nuclei of the thalamus for localization-related epilepsy. |
2010-06-29 |
2023-08-12 |
Not clear |
| D Battaglia, P Veggiotti, D Lettori, G Tamburrini, T Tartaglione, A Graziano, C Veredice, A Sacco, D Chieffo, A Pecoraro, C Colosimo, C Di Rocco, Ch Dravet, F Guzzett. Functional hemispherectomy in children with epilepsy and CSWS due to unilateral early brain injury including thalamus: sudden recovery of CSWS. Epilepsy research. vol 87. issue 2-3. 2010-02-18. PMID:19879110. |
functional hemispherectomy in children with epilepsy and csws due to unilateral early brain injury including thalamus: sudden recovery of csws. |
2010-02-18 |
2023-08-12 |
Not clear |
| D Battaglia, P Veggiotti, D Lettori, G Tamburrini, T Tartaglione, A Graziano, C Veredice, A Sacco, D Chieffo, A Pecoraro, C Colosimo, C Di Rocco, Ch Dravet, F Guzzett. Functional hemispherectomy in children with epilepsy and CSWS due to unilateral early brain injury including thalamus: sudden recovery of CSWS. Epilepsy research. vol 87. issue 2-3. 2010-02-18. PMID:19879110. |
to try to prove in patients with refractory symptomatic epilepsy due to early brain injury involving thalamus and complicated by csws the effects of the isolation of the injured hemisphere, performed with functional hemisperectomy, on epilepsy, namely on csws. |
2010-02-18 |
2023-08-12 |
Not clear |
| Juliana Lockman, Robert S Fishe. Therapeutic brain stimulation for epilepsy. Neurologic clinics. vol 27. issue 4. 2010-01-08. PMID:19853222. |
a pivotal large, double-blind controlled trial of anterior nucleus of the thalamus has recently been completed, and it showed efficacy for partial seizures with or without secondary generalization.28 a controlled trial for rns is underway.57 in addition, pilot studies of hippocampal stimulation 41,43 are expected to lead to more definitive trials of this site.brain stimulation for epilepsy holds several challenges for the future. |
2010-01-08 |
2023-08-12 |
human |
| Sandrine Saillet, Mélanie Langlois, Berend Feddersen, Lorella Minotti, Laurent Vercueil, Stephan Chabardès, Olivier David, Antoine Depaulis, Colin Deransart, Philippe Kahan. Manipulating the epileptic brain using stimulation: a review of experimental and clinical studies. Epileptic disorders : international epilepsy journal with videotape. vol 11. issue 2. 2009-09-18. PMID:19473948. |
the rationale for targeting specific areas that have thus far been considered (i.e., vagus nerve, cerebellum, anterior or centromedial thalamus, basal ganglia, cortex and temporal lobe) is addressed in the light of experimental data and clinical effectiveness in different models and forms of epilepsy. |
2009-09-18 |
2023-08-12 |
Not clear |
| Andrea Eugenio Cavanna, Francesco Monac. Brain mechanisms of altered conscious states during epileptic seizures. Nature reviews. Neurology. vol 5. issue 5. 2009-08-11. PMID:19488084. |
findings from neurophysiological and brain-imaging studies in epilepsy have now demonstrated that involvement of the bilateral thalamus and upper brainstem leads to selective impairment of frontoparietal association cortices and midline 'default mode' networks, which results in ictal loss of consciousness. |
2009-08-11 |
2023-08-12 |
Not clear |
| Michael Seidenberg, Bruce Hermann, Dalin Pulsipher, Jared Morton, Joy Parrish, Elizabeth Geary, Leslie Guidott. Thalamic atrophy and cognition in unilateral temporal lobe epilepsy. Journal of the International Neuropsychological Society : JINS. vol 14. issue 3. 2008-07-15. PMID:18419837. |
ipsilateral hippocampal volume was significantly correlated with both early neurodevelopmental features (age of seizure onset) and disease characteristics (duration of epilepsy), whereas thalamus integrity was related only to disease variables. |
2008-07-15 |
2023-08-12 |
human |
| Pavle M Joksovic, Douglas F Covey, Slobodan M Todorovi. Inhibition of T-type calcium current in the reticular thalamic nucleus by a novel neuroactive steroid. Annals of the New York Academy of Sciences. vol 1122. 2008-04-21. PMID:18077566. |
neurons of the nucleus reticularis of the thalamus (nrt) serve as an important inhibitory gate that controls trafficking of thalamocortical sensory signals and states of sleep, arousal, and epilepsy. |
2008-04-21 |
2023-08-12 |
rat |