| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alison L Althaus, Shannon J Moore, Helen Zhang, Xi Du, Geoffrey G Murphy, Jack M Paren. Altered Synaptic Drive onto Birthdated Dentate Granule Cells in Experimental Temporal Lobe Epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 38. 2020-06-30. PMID:31270158. |
dysregulated adult hippocampal neurogenesis occurs in many temporal lobe epilepsy (tle) models. |
2020-06-30 |
2023-08-13 |
rat |
| Victor Navarrete-Modesto, Sandra Orozco-Suárez, Mario Alonso-Vanegas, Iris A Feria-Romero, Luisa Roch. REST/NRSF transcription factor is overexpressed in hippocampus of patients with drug-resistant mesial temporal lobe epilepsy. Epilepsy & behavior : E&B. vol 94. 2020-06-29. PMID:30903955. |
rest/nrsf transcription factor is overexpressed in hippocampus of patients with drug-resistant mesial temporal lobe epilepsy. |
2020-06-29 |
2023-08-13 |
human |
| Victor Navarrete-Modesto, Sandra Orozco-Suárez, Mario Alonso-Vanegas, Iris A Feria-Romero, Luisa Roch. REST/NRSF transcription factor is overexpressed in hippocampus of patients with drug-resistant mesial temporal lobe epilepsy. Epilepsy & behavior : E&B. vol 94. 2020-06-29. PMID:30903955. |
in the present study, the expression of rest/nrsf (messenger ribonucleic acid (mrna) and protein) was evaluated in the hippocampus of 28 patients with drug-resistant mesial temporal lobe epilepsy (mtle) and their correlation with clinical variables and comorbid anxiety and depression. |
2020-06-29 |
2023-08-13 |
human |
| Ahmad Marashly, Jennifer Koop, Michelle Loman, Irene Kim, Mohit Maheshwari, Sean M Le. Multiple hippocampal transections for refractory pediatric mesial temporal lobe epilepsy: seizure and neuropsychological outcomes. Journal of neurosurgery. Pediatrics. 2020-06-26. PMID:32590352. |
multiple hippocampal transections for refractory pediatric mesial temporal lobe epilepsy: seizure and neuropsychological outcomes. |
2020-06-26 |
2023-08-13 |
Not clear |
| Parul Varma, Rebecca Brulet, Ling Zhang, Jenny Hsie. Targeting Seizure-Induced Neurogenesis in a Clinically Relevant Time Period Leads to Transient But Not Persistent Seizure Reduction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 35. 2020-06-23. PMID:31308098. |
mesial temporal lobe epilepsy (mtle), the most common form of medically refractory epilepsy in adults, is usually associated with hippocampal pathophysiology. |
2020-06-23 |
2023-08-13 |
mouse |
| Bernhard J Steinhoff, Anke M Staac. Is there a place for surgical treatment of nonpharmacoresistant epilepsy? Epilepsy & behavior : E&B. vol 91. 2020-06-16. PMID:29960857. |
epilepsy surgery has been shown to be the best possible treatment in well-defined and difficult-to-treat epilepsy syndromes, such as mesial temporal lobe epilepsy with unilateral hippocampal sclerosis, even early in the course of the disease if pharmacoresistance is proven. |
2020-06-16 |
2023-08-13 |
Not clear |
| Laurence de Nijs, Kyonghwan Choe, Hellen Steinbusch, Olaf E M G Schijns, Jim Dings, Daniel L A van den Hove, Bart P F Rutten, Govert Hooglan. DNA methyltransferase isoforms expression in the temporal lobe of epilepsy patients with a history of febrile seizures. Clinical epigenetics. vol 11. issue 1. 2020-06-15. PMID:31426844. |
temporal lobe epilepsy (tle) with hippocampal sclerosis (hs) is a common pharmaco-resistant epilepsy referred for adult epilepsy surgery. |
2020-06-15 |
2023-08-13 |
Not clear |
| Travis R Stoub, Ada V Chicharro, Christopher L Grote, Andres M Kanne. Disconnection of hippocampal networks contributes to memory dysfunction in individuals with temporal lobe epilepsy. Hippocampus. vol 29. issue 5. 2020-05-28. PMID:28888031. |
disconnection of hippocampal networks contributes to memory dysfunction in individuals with temporal lobe epilepsy. |
2020-05-28 |
2023-08-13 |
Not clear |
| Travis R Stoub, Ada V Chicharro, Christopher L Grote, Andres M Kanne. Disconnection of hippocampal networks contributes to memory dysfunction in individuals with temporal lobe epilepsy. Hippocampus. vol 29. issue 5. 2020-05-28. PMID:28888031. |
the purpose of this study is to evaluate the relationship between the volume of the hippocampus, entorhinal cortex along with the surrounding parahippocampal white matter and memory performance in those with temporal lobe epilepsy. |
2020-05-28 |
2023-08-13 |
Not clear |
| Travis R Stoub, Ada V Chicharro, Christopher L Grote, Andres M Kanne. Disconnection of hippocampal networks contributes to memory dysfunction in individuals with temporal lobe epilepsy. Hippocampus. vol 29. issue 5. 2020-05-28. PMID:28888031. |
these results show that a decrease in white matter fibers projecting to the hippocampus may cause a disruption of incoming multi-modal sensory information, contributing to the memory decline seen in individuals with temporal lobe epilepsy. |
2020-05-28 |
2023-08-13 |
Not clear |
| Michael F Hammer, Ryan Sprissler, Robert W Bina, Branden Lau, Laurel Johnstone, Christina M Walter, David M Labiner, Martin E Weinan. Altered expression of signaling pathways regulating neuronal excitability in hippocampal tissue of temporal lobe epilepsy patients with low and high seizure frequency. Epilepsy research. vol 155. 2020-05-26. PMID:31195185. |
altered expression of signaling pathways regulating neuronal excitability in hippocampal tissue of temporal lobe epilepsy patients with low and high seizure frequency. |
2020-05-26 |
2023-08-13 |
Not clear |
| Jae Young Kwon, Un Ju Jung, Dong Woon Kim, Sehwan Kim, Gyeong Joon Moon, Jungwan Hong, Min-Tae Jeon, Minsang Shin, Jeong Ho Chang, Sang Ryong Ki. Beneficial Effects of Hesperetin in a Mouse Model of Temporal Lobe Epilepsy. Journal of medicinal food. vol 21. issue 12. 2020-05-12. PMID:30136878. |
abnormal reorganization of the dentate gyrus and neuroinflammation in the hippocampus represent characteristic phenotypes of patients suffering from temporal lobe epilepsy. |
2020-05-12 |
2023-08-13 |
mouse |
| Julia B Kahn, Russell G Port, Cuiyong Yue, Hajime Takano, Douglas A Coulte. Circuit-based interventions in the dentate gyrus rescue epilepsy-associated cognitive dysfunction. Brain : a journal of neurology. vol 142. issue 9. 2020-05-12. PMID:31363737. |
temporal lobe epilepsy is associated with significant structural pathology in the hippocampus. |
2020-05-12 |
2023-08-13 |
mouse |
| Eugene Chun, Argyle V Bumanglag, Sara N Burke, Robert S Slovite. Targeted hippocampal GABA neuron ablation by Stable Substance P-saporin causes hippocampal sclerosis and chronic epilepsy in rats. Epilepsia. vol 60. issue 5. 2020-04-27. PMID:30963545. |
cryptogenic temporal lobe epilepsy develops in the absence of identified brain injuries, infections, or structural malformations, and in these cases, an unidentified pre-existing abnormality may initiate febrile seizures, hippocampal sclerosis, and epilepsy. |
2020-04-27 |
2023-08-13 |
rat |
| Eugene Chun, Argyle V Bumanglag, Sara N Burke, Robert S Slovite. Targeted hippocampal GABA neuron ablation by Stable Substance P-saporin causes hippocampal sclerosis and chronic epilepsy in rats. Epilepsia. vol 60. issue 5. 2020-04-27. PMID:30963545. |
in this study, hippocampal gaba neurons were targeted for selective elimination to determine whether a focal hippocampal gabaergic defect in an otherwise normal brain can initiate cryptogenic temporal lobe epilepsy with hippocampal sclerosis. |
2020-04-27 |
2023-08-13 |
rat |
| Eugene Chun, Argyle V Bumanglag, Sara N Burke, Robert S Slovite. Targeted hippocampal GABA neuron ablation by Stable Substance P-saporin causes hippocampal sclerosis and chronic epilepsy in rats. Epilepsia. vol 60. issue 5. 2020-04-27. PMID:30963545. |
these data suggest that hippocampal gabaergic dysfunction is epileptogenic and can produce the defining features of cryptogenic temporal lobe epilepsy. |
2020-04-27 |
2023-08-13 |
rat |
| Jana Desloovere, Paul Boon, Lars E Larsen, Caroline Merckx, Marie-Gabrielle Goossens, Chris Van den Haute, Veerle Baekelandt, Dimitri De Bundel, Evelien Carrette, Jean Delbeke, Alfred Meurs, Kristl Vonck, Wytse Wadman, Robrecht Raed. Long-term chemogenetic suppression of spontaneous seizures in a mouse model for temporal lobe epilepsy. Epilepsia. vol 60. issue 11. 2020-04-15. PMID:31608439. |
in this study, we evaluated the effect of chemogenetic suppression of excitatory pyramidal and granule cell neurons of the sclerotic hippocampus in the intrahippocampal mouse model (ihka) for temporal lobe epilepsy. |
2020-04-15 |
2023-08-13 |
mouse |
| Wendy Klement, Marine Blaquiere, Emma Zub, Frederic deBock, Fabien Boux, Emmanuel Barbier, Etienne Audinat, Mireille Lerner-Natoli, Nicola March. A pericyte-glia scarring develops at the leaky capillaries in the hippocampus during seizure activity. Epilepsia. vol 60. issue 7. 2020-04-14. PMID:31135065. |
here, we tested the hypothesis that a pericyte-glia scar forms around the outer wall of hippocampal capillaries in a model of temporal lobe epilepsy associated with hippocampal sclerosis. |
2020-04-14 |
2023-08-13 |
Not clear |
| Elisabeth Roggenhofer, Emiliano Santarnecchi, Sandrine Muller, Ferath Kherif, Roland Wiest, Margitta Seeck, Bogdan Dragansk. Trajectories of brain remodeling in temporal lobe epilepsy. Journal of neurology. vol 266. issue 12. 2020-04-14. PMID:31549200. |
we acquired mris from a large cohort of mesial temporal lobe epilepsy patients with or without hippocampus sclerosis on radiological examination. |
2020-04-14 |
2023-08-13 |
Not clear |
| Elisabeth Roggenhofer, Emiliano Santarnecchi, Sandrine Muller, Ferath Kherif, Roland Wiest, Margitta Seeck, Bogdan Dragansk. Trajectories of brain remodeling in temporal lobe epilepsy. Journal of neurology. vol 266. issue 12. 2020-04-14. PMID:31549200. |
the main effect of disease was associated with continuous hippocampus volume loss ipsilateral to the seizure onset zone in both temporal lobe epilepsy cohorts. |
2020-04-14 |
2023-08-13 |
Not clear |