Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Tushar Deshpande, Tingsong Li, Lukas Henning, Zhou Wu, Julia Müller, Gerald Seifert, Christian Steinhäuser, Peter Bedne. Constitutive deletion of astrocytic connexins aggravates kainate-induced epilepsy. Glia. vol 68. issue 10. 2021-11-11. PMID:32240558. |
loss of interastrocytic gap junction (gj) coupling has been observed in the sclerotic hippocampus of patients with mesial temporal lobe epilepsy (mtle) and in mouse models of mtle, leading to the suggestion that it plays a causative role in the pathogenesis. |
2021-11-11 |
2023-08-13 |
mouse |
Akhila Ajith, Supratim Mondal, Sutirtha Chattopadhyay, Anubhav Kumar, Yeswanth Sthanikam, Ari George Chacko, Krishna Prabhu, Geeta Chacko, Harshad Arvind Vanjare, Ramanna Valmiki Rajesh, Shibdas Banerje. Mass Spectrometry Imaging Deciphers Dysregulated Lipid Metabolism in the Human Hippocampus Affected by Temporal Lobe Epilepsy. ACS chemical neuroscience. vol 12. issue 21. 2021-11-11. PMID:34657435. |
mass spectrometry imaging deciphers dysregulated lipid metabolism in the human hippocampus affected by temporal lobe epilepsy. |
2021-11-11 |
2023-08-13 |
human |
Akhila Ajith, Supratim Mondal, Sutirtha Chattopadhyay, Anubhav Kumar, Yeswanth Sthanikam, Ari George Chacko, Krishna Prabhu, Geeta Chacko, Harshad Arvind Vanjare, Ramanna Valmiki Rajesh, Shibdas Banerje. Mass Spectrometry Imaging Deciphers Dysregulated Lipid Metabolism in the Human Hippocampus Affected by Temporal Lobe Epilepsy. ACS chemical neuroscience. vol 12. issue 21. 2021-11-11. PMID:34657435. |
temporal lobe epilepsy (tle) is the most prevalent form of human epilepsy, often accompanied by neurodegeneration in the hippocampus. |
2021-11-11 |
2023-08-13 |
human |
Sarah S El-Sayed, Mohammed F El-Yamany, Hesham A Salem, Ayman E El-Saha. New insights into the effects of vinpocetine against neurobehavioral comorbidities in a rat model of temporal lobe epilepsy via the downregulation of the hippocampal PI3K/mTOR signalling pathway. The Journal of pharmacy and pharmacology. vol 73. issue 5. 2021-11-08. PMID:33772295. |
new insights into the effects of vinpocetine against neurobehavioral comorbidities in a rat model of temporal lobe epilepsy via the downregulation of the hippocampal pi3k/mtor signalling pathway. |
2021-11-08 |
2023-08-13 |
rat |
b' Estefan\\xc3\\xada Conde-Blanco, Sa\\xc3\\xbcl Pascual-Diaz, Mar Carre\\xc3\\xb1o, Emma Mu\\xc3\\xb1oz-Moreno, Jos\\xc3\\xa9 Carlos Pariente, Teresa Boget, Isabel Manzanares, Antonio Donaire, Mar\\xc3\\xada Centeno, Francesc Graus, Nuria Bargall\\xc3\\xb. Volumetric and shape analysis of the hippocampus in temporal lobe epilepsy with GAD65 antibodies compared with non-immune epilepsy. Scientific reports. vol 11. issue 1. 2021-11-08. PMID:33986308.' |
volumetric and shape analysis of the hippocampus in temporal lobe epilepsy with gad65 antibodies compared with non-immune epilepsy. |
2021-11-08 |
2023-08-13 |
Not clear |
Yiwei Zhang, Wanchen Dou, Zhentao Zuo, Hui You, Yuelei Lv, Bo Hou, Lin Shi, Feng Fen. Brain volume and perfusion asymmetry in temporal lobe epilepsy with and without hippocampal sclerosis. Neurological research. vol 43. issue 4. 2021-11-05. PMID:33320070. |
brain volume and perfusion asymmetry in temporal lobe epilepsy with and without hippocampal sclerosis. |
2021-11-05 |
2023-08-13 |
Not clear |
Fatemeh Fadaie, Hyo M Lee, Benoit Caldairou, Ravnoor S Gill, Viviane Sziklas, Joelle Crane, Boris C Bernhardt, Seok-Jun Hong, Andrea Bernasconi, Neda Bernascon. Atypical functional connectome hierarchy impacts cognition in temporal lobe epilepsy. Epilepsia. vol 62. issue 11. 2021-11-02. PMID:34490890. |
drug-resistant temporal lobe epilepsy (tle) is typically associated with hippocampal pathology. |
2021-11-02 |
2023-08-13 |
Not clear |
D I Pitskhelauri, E S Kudieva, A G Melikyan, P A Vlasov, M I Kamenetskaya, O S Zaitsev, A B Kozlova, N M Eliseeva, L V Shishkina, G V Danilov, I A Nagorskaya, A Z Sanikidze, T V Melnikova-Pitskhelauri, I N Pronin, A N Konovalo. [Surgical treatment of drug-resistant epilepsy following hippocampal sclerosis]. Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko. vol 85. issue 5. 2021-11-02. PMID:34714001. |
surgery is an effective approach for drug-resistant temporal lobe epilepsy following hippocampal sclerosis. |
2021-11-02 |
2023-08-13 |
Not clear |
Tih-Shih Lee, Alexander Y Li, Amedeo Rapuano, John Mantis, Tore Eid, Thomas N Seyfried, Nihal C de Laneroll. Gene expression in the epileptic (EL) mouse hippocampus. Neurobiology of disease. vol 147. 2021-11-01. PMID:33153970. |
the neuropathology of hippocampal seizure foci in human temporal lobe epilepsy (tle) and several animal models of epilepsy reveal extensive neuronal loss along with astrocyte and microglial activation. |
2021-11-01 |
2023-08-13 |
mouse |
Masashi Mizutani, Daichi Sone, Terunori Sano, Yukio Kimura, Norihide Maikusa, Yoko Shigemoto, Yuichi Goto, Masaki Takao, Masaki Iwasaki, Hiroshi Matsuda, Noriko Sato, Yuko Sait. Histopathological validation and clinical correlates of hippocampal subfield volumetry based on T2-weighted MRI in temporal lobe epilepsy with hippocampal sclerosis. Epilepsy research. vol 177. 2021-11-01. PMID:34521044. |
histopathological validation and clinical correlates of hippocampal subfield volumetry based on t2-weighted mri in temporal lobe epilepsy with hippocampal sclerosis. |
2021-11-01 |
2023-08-13 |
Not clear |
Masashi Mizutani, Daichi Sone, Terunori Sano, Yukio Kimura, Norihide Maikusa, Yoko Shigemoto, Yuichi Goto, Masaki Takao, Masaki Iwasaki, Hiroshi Matsuda, Noriko Sato, Yuko Sait. Histopathological validation and clinical correlates of hippocampal subfield volumetry based on T2-weighted MRI in temporal lobe epilepsy with hippocampal sclerosis. Epilepsy research. vol 177. 2021-11-01. PMID:34521044. |
the objectives of this study were 1) to histologically validate the hippocampal subfield volumetry based on t2-weighted mri, and 2) to explore its clinical impact on postsurgical memory function and seizure outcome in temporal lobe epilepsy (tle) with hippocampal sclerosis (hs). |
2021-11-01 |
2023-08-13 |
Not clear |
Yoko Shigemoto, Noriko Sato, Daichi Sone, Norihide Maikusa, Tensho Yamao, Yukio Kimura, Emiko Chiba, Fumio Suzuki, Hiroyuki Fujii, Yutaro Takayama, Masaki Iwasaki, Eiji Nakagawa, Hiroshi Matsud. Single-subject gray matter networks in temporal lobe epilepsy patients with hippocampal sclerosis. Epilepsy research. vol 177. 2021-11-01. PMID:34534926. |
single-subject gray matter networks in temporal lobe epilepsy patients with hippocampal sclerosis. |
2021-11-01 |
2023-08-13 |
Not clear |
Benoit Caldairou, Niels A Foit, Carlotta Mutti, Fatemeh Fadaie, Ravnoor Gill, Hyo Min Lee, Theo Demerath, Horst Urbach, Andreas Schulze-Bonhage, Andrea Bernasconi, Neda Bernascon. MRI-Based Machine Learning Prediction Framework to Lateralize Hippocampal Sclerosis in Patients With Temporal Lobe Epilepsy. Neurology. vol 97. issue 16. 2021-10-29. PMID:34475125. |
mri-based machine learning prediction framework to lateralize hippocampal sclerosis in patients with temporal lobe epilepsy. |
2021-10-29 |
2023-08-13 |
Not clear |
Benoit Caldairou, Niels A Foit, Carlotta Mutti, Fatemeh Fadaie, Ravnoor Gill, Hyo Min Lee, Theo Demerath, Horst Urbach, Andreas Schulze-Bonhage, Andrea Bernasconi, Neda Bernascon. MRI-Based Machine Learning Prediction Framework to Lateralize Hippocampal Sclerosis in Patients With Temporal Lobe Epilepsy. Neurology. vol 97. issue 16. 2021-10-29. PMID:34475125. |
mri fails to reveal hippocampal pathology in 30% to 50% of temporal lobe epilepsy (tle) surgical candidates. |
2021-10-29 |
2023-08-13 |
Not clear |
Kan Deng, Rushi Zou, Bingsheng Huang, Ping Zeng, Dong Liang, Lifei Huang, Guo Bin, Dongfang Zou, Hongwu Zeng, Jian Zhan. Abnormalities of Cortical Thickness in Pediatric Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis. Current medical imaging. vol 16. issue 9. 2021-10-26. PMID:33135613. |
abnormalities of cortical thickness in pediatric mesial temporal lobe epilepsy with hippocampal sclerosis. |
2021-10-26 |
2023-08-13 |
Not clear |
Kan Deng, Rushi Zou, Bingsheng Huang, Ping Zeng, Dong Liang, Lifei Huang, Guo Bin, Dongfang Zou, Hongwu Zeng, Jian Zhan. Abnormalities of Cortical Thickness in Pediatric Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis. Current medical imaging. vol 16. issue 9. 2021-10-26. PMID:33135613. |
mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs) is the most common intractable seizure type of pediatric epilepsy, with alterations in the cortex across the whole brain. |
2021-10-26 |
2023-08-13 |
Not clear |
Dong Ah Lee, Ho-Joon Lee, Hyung Chan Kim, Kang Min Par. Temporal lobe epilepsy with or without hippocampal sclerosis: Structural and functional connectivity using advanced MRI techniques. Journal of neuroimaging : official journal of the American Society of Neuroimaging. vol 31. issue 5. 2021-10-26. PMID:34110654. |
temporal lobe epilepsy with or without hippocampal sclerosis: structural and functional connectivity using advanced mri techniques. |
2021-10-26 |
2023-08-13 |
Not clear |
Dong Ah Lee, Ho-Joon Lee, Hyung Chan Kim, Kang Min Par. Temporal lobe epilepsy with or without hippocampal sclerosis: Structural and functional connectivity using advanced MRI techniques. Journal of neuroimaging : official journal of the American Society of Neuroimaging. vol 31. issue 5. 2021-10-26. PMID:34110654. |
the aim of this study was to investigate the differences in structural connectivity based on diffusion tensor imaging (dti) and functional connectivity based on arterial spin labeling (asl) mri between temporal lobe epilepsy (tle) patients with and without hippocampal sclerosis (hs). |
2021-10-26 |
2023-08-13 |
Not clear |
Soumil Dey, Aparna Banerjee Dixit, Manjari Tripathi, Ramesh Sharanappa Doddamani, Mehar Chand Sharma, Sanjeev Lalwani, Poodipedi Sarat Chandra, Jyotirmoy Banerje. Altered hippocampal kynurenine pathway metabolism contributes to hyperexcitability in human mesial temporal lobe epilepsy-hippocampal sclerosis. British journal of pharmacology. vol 178. issue 19. 2021-10-25. PMID:33990935. |
glutamate receptor-mediated enhanced excitatory neurotransmission is typically associated with mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs). |
2021-10-25 |
2023-08-13 |
human |
Karl Roessler, Burkhard S Kasper, Julia Shawarba, Katrin Walther, Roland Coras, Sebastian Brandner, Fabian Winter, Hajo Hamer, Ingmar Blumcke, Michael Buchfelde. Operative variations in temporal lobe epilepsy surgery and seizure and memory outcome in 226 patients suffering from hippocampal sclerosis. Neurological research. vol 43. issue 11. 2021-10-22. PMID:34156329. |
operative variations in temporal lobe epilepsy surgery and seizure and memory outcome in 226 patients suffering from hippocampal sclerosis. |
2021-10-22 |
2023-08-13 |
Not clear |