| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M J Koepp, C Labb\\xc3\\xa9, M P Richardson, D J Brooks, W Van Paesschen, V J Cunningham, J S Dunca. Regional hippocampal [11C]flumazenil PET in temporal lobe epilepsy with unilateral and bilateral hippocampal sclerosis. Brain : a journal of neurology. vol 120 ( Pt 10). 1997-12-10. PMID:9365376. |
reduction of cbzr binding was consistently over and above loss of hippocampal volume indicating that atrophy is not the sole determinant of cbzr loss in mesial temporal lobe epilepsy. |
1997-12-10 |
2023-08-12 |
Not clear |
| K S Hand, V H Baird, W Van Paesschen, M J Koepp, T Revesz, M Thom, W F Harkness, J S Duncan, N G Bower. Central benzodiazepine receptor autoradiography in hippocampal sclerosis. British journal of pharmacology. vol 122. issue 2. 1997-12-08. PMID:9313947. |
hippocampal tissue was obtained at surgery from 8 patients with intractable temporal lobe epilepsy (tle) due to hs and autopsies of 6 neurologically normal controls. |
1997-12-08 |
2023-08-12 |
Not clear |
| M Esclapez, J C Hirsch, R Khazipov, Y Ben-Ari, C Bernar. Operative GABAergic inhibition in hippocampal CA1 pyramidal neurons in experimental epilepsy. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 22. 1997-12-04. PMID:9342378. |
patch-clamp recordings of ca1 interneurons and pyramidal cells were performed in hippocampal slices from kainate- or pilocarpine-treated rat models of temporal lobe epilepsy. |
1997-12-04 |
2023-08-12 |
rat |
| G von Campe, D D Spencer, N C de Laneroll. Morphology of dentate granule cells in the human epileptogenic hippocampus. Hippocampus. vol 7. issue 5. 1997-12-04. PMID:9347345. |
hippocampal dentate granule cells in temporal lobe epilepsy (tle) patients with mesial sclerosis (mtle) are reported to be hyperexcitable compared to those in patients with a mass lesion outside the hippocampus (matle) (williamson, clin neurosci 1994;2: 47-52). |
1997-12-04 |
2023-08-12 |
human |
| B Szelies, G Weber-Luxenburger, G Pawlik, J Kessler, V Holthoff, R Mielke, K Herholz, B Bauer, K Wienhard, W D Heis. MRI-guided flumazenil- and FDG-PET in temporal lobe epilepsy. NeuroImage. vol 3. issue 2. 1997-12-02. PMID:9345482. |
in temporal lobe epilepsy (tle) patients without lesions, major hippocampal sclerosis, or atrophy on magnetic resonance imaging (mri), the localizing power of [11c]flumazenil (fmz) and 2-[18f]fluoro-2-deoxy-d-glucose (fdg) was compared using high-resolution positron emission tomography (pet) studies and individually coregistered mri scans. |
1997-12-02 |
2023-08-12 |
Not clear |
| J J Wasenko, A M Gharagozloo, M V Smith, D Thoma. High resolution MR technique in the diagnosis of mesial temporal sclerosis. Correlative MRI and pathological features. Clinical imaging. vol 21. issue 5. 1997-11-20. PMID:9316749. |
mesial temporal sclerosis, otherwise known as hippocampal sclerosis, is the most common entity associated with medically intractable temporal lobe epilepsy. |
1997-11-20 |
2023-08-12 |
Not clear |
| W B Barr, M Ashtari, N Schau. Bilateral reductions in hippocampal volume in adults with epilepsy and a history of febrile seizures. Journal of neurology, neurosurgery, and psychiatry. vol 63. issue 4. 1997-11-19. PMID:9343124. |
to examine the degree and frequency of reductions in hippocampal volume in patients with temporal lobe epilepsy with and without a history of febrile seizures. |
1997-11-19 |
2023-08-12 |
Not clear |
| M Weckesser, A Hufnagel, K Ziemons, M Griessmeier, F Sonnenberg, T Hackl\\xc3\\xa4nder, K J Langen, M Holschbach, C E Elger, H M\\xc3\\xbcller-G\\xc3\\xa4rtne. Effect of partial volume correction on muscarinic cholinergic receptor imaging with single-photon emission tomography in patients with temporal lobe epilepsy. European journal of nuclear medicine. vol 24. issue 9. 1997-11-18. PMID:9283110. |
animal experiments and preliminary results in humans have indicated alterations of hippocampal muscarinic acetylcholine receptors (machr) in temporal lobe epilepsy. |
1997-11-18 |
2023-08-12 |
Not clear |
| M Weckesser, A Hufnagel, K Ziemons, M Griessmeier, F Sonnenberg, T Hackl\\xc3\\xa4nder, K J Langen, M Holschbach, C E Elger, H M\\xc3\\xbcller-G\\xc3\\xa4rtne. Effect of partial volume correction on muscarinic cholinergic receptor imaging with single-photon emission tomography in patients with temporal lobe epilepsy. European journal of nuclear medicine. vol 24. issue 9. 1997-11-18. PMID:9283110. |
patients with temporal lobe epilepsy often present with a reduction in hippocampal volume. |
1997-11-18 |
2023-08-12 |
Not clear |
| M Weckesser, A Hufnagel, K Ziemons, M Griessmeier, F Sonnenberg, T Hackl\\xc3\\xa4nder, K J Langen, M Holschbach, C E Elger, H M\\xc3\\xbcller-G\\xc3\\xa4rtne. Effect of partial volume correction on muscarinic cholinergic receptor imaging with single-photon emission tomography in patients with temporal lobe epilepsy. European journal of nuclear medicine. vol 24. issue 9. 1997-11-18. PMID:9283110. |
the aim of this study was to investigate the influence of hippocampal atrophy on the quantification of machr with single photon emission tomography (spet) in patients with temporal lobe epilepsy. |
1997-11-18 |
2023-08-12 |
Not clear |
| M Guentchev, J A Hainfellner, G R Trabattoni, H Budk. Distribution of parvalbumin-immunoreactive neurons in brain correlates with hippocampal and temporal cortical pathology in Creutzfeldt-Jakob disease. Journal of neuropathology and experimental neurology. vol 56. issue 10. 1997-10-31. PMID:9329455. |
we studied hippocampus and temporal cortex from human cjd and control autopsy brains and surgical cryptogenic temporal lobe epilepsy specimens for distribution and density of parvalbumin (pv) and calbindin-d28k (cal) -positive neurons that are subpopulations of gabaergic neurons. |
1997-10-31 |
2023-08-12 |
human |
| P S Buckmaster, F E Dude. Neuron loss, granule cell axon reorganization, and functional changes in the dentate gyrus of epileptic kainate-treated rats. The Journal of comparative neurology. vol 385. issue 3. 1997-10-28. PMID:9300766. |
these findings from the dentate gyrus of epileptic kainate-treated rats are strikingly similar to those reported for human temporal lobe epilepsy, and they suggest that neuron loss and axon reorganization in the temporal hippocampus may be important in epileptogenesis. |
1997-10-28 |
2023-08-12 |
human |
| D H Lowenstei. Recent advances related to basic mechanisms of epileptogenesis. Epilepsy research. Supplement. vol 11. 1997-10-24. PMID:9294727. |
the most substantial progress has been made in work related to temporal lobe epilepsy (tle), where the biochemical, electrophysiological and anatomical changes in the hippocampus have been intensively studied. |
1997-10-24 |
2023-08-12 |
mouse |
| D Lurton, E A Cavalheir. Neuropeptide-Y immunoreactivity in the pilocarpine model of temporal lobe epilepsy. Experimental brain research. vol 116. issue 1. 1997-10-23. PMID:9305828. |
neuropeptide-y (npy) is expressed by granule cells and mossy fibres of the hippocampal dentate gyrus during experimental temporal lobe epilepsy (tle). |
1997-10-23 |
2023-08-12 |
Not clear |
| J Bengzon, Z Kokaia, E Elm\\xc3\\xa9r, A Nanobashvili, M Kokaia, O Lindval. Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 19. 1997-10-21. PMID:9294228. |
we hypothesize that these processes, occurring early during epileptogenesis, are primary events in the development of hippocampal pathology in animals and possibly also in patients suffering from temporal lobe epilepsy. |
1997-10-21 |
2023-08-12 |
human |
| J Jolkkonen, K K\\xc3\\xa4hk\\xc3\\xb6nen, A Pitk\\xc3\\xa4ne. Cholinergic deafferentation exacerbates seizure-induced loss of somatostatin-immunoreactive neurons in the rat hippocampus. Neuroscience. vol 80. issue 2. 1997-10-17. PMID:9284343. |
the loss of somatostatin-immunoreactive neurons and the sprouting of mossy fibers are typical histopathological abnormalities in the hippocampus in experimental and human temporal lobe epilepsy. |
1997-10-17 |
2023-08-12 |
human |
| M J Koepp, M P Richardson, C Labb\\xc3\\xa9, D J Brooks, V J Cunningham, J Ashburner, W Van Paesschen, T Revesz, J S Dunca. 11C-flumazenil PET, volumetric MRI, and quantitative pathology in mesial temporal lobe epilepsy. Neurology. vol 49. issue 3. 1997-10-10. PMID:9305338. |
using statistical parametric mapping and 11c-flumazenil (fmz) pet we have previously shown reduction of central benzodiazepine receptor (cbzr) binding restricted to the hippocampus in mesial temporal lobe epilepsy (mtle) due to hippocampal sclerosis (hs). |
1997-10-10 |
2023-08-12 |
Not clear |
| C Schwarzer, K Tsunashima, C Wanzenb\\xc3\\xb6ck, K Fuchs, W Sieghart, G Sper. GABA(A) receptor subunits in the rat hippocampus II: altered distribution in kainic acid-induced temporal lobe epilepsy. Neuroscience. vol 80. issue 4. 1997-10-07. PMID:9284056. |
gaba(a) receptor subunits in the rat hippocampus ii: altered distribution in kainic acid-induced temporal lobe epilepsy. |
1997-10-07 |
2023-08-12 |
human |
| S Kar, D Seto, S Dor\\xc3\\xa9, J G Chabot, R Quirio. Systemic administration of kainic acid induces selective time dependent decrease in [125I]insulin-like growth factor I, [125I]insulin-like growth factor II and [125I]insulin receptor binding sites in adult rat hippocampal formation. Neuroscience. vol 80. issue 4. 1997-10-07. PMID:9284059. |
administration of kainic acid evokes acute seizure in hippocampal pathways that results in a complex sequence of functional and structural alterations resembling human temporal lobe epilepsy. |
1997-10-07 |
2023-08-12 |
human |
| P S Mangan, E H Bertra. Shortened-duration GABA(A) receptor-mediated synaptic potentials underlie enhanced CA1 excitability in a chronic model of temporal lobe epilepsy. Neuroscience. vol 80. issue 4. 1997-10-07. PMID:9284063. |
intracellular recording techniques were used to examine gaba(a) receptor-mediated synaptic inhibition in pyramidal cells of the ca1 region of the rat hippocampus in the post-self sustaining limbic status epilepticus model of temporal lobe epilepsy. |
1997-10-07 |
2023-08-12 |
rat |