Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Gary W Mathern, P David Adelson, Leslie D Cahan, Joao P Leit. Hippocampal neuron damage in human epilepsy: Meyer's hypothesis revisited. Progress in brain research. vol 135. 2002-08-22. PMID:12143344. |
to address this question, this study examined hippocampal specimens from temporal lobe epilepsy patients (tle; n = 572) and those with extra-temporal seizures and pathologies (n = 73) for qualitative signs of hippocampal sclerosis and quantitative neuron loss using cell counting techniques. |
2002-08-22 |
2023-08-12 |
human |
b' Reetta K\\xc3\\xa4lvi\\xc3\\xa4inen, Tuuli Salmenper\\xc3\\xa. Do recurrent seizures cause neuronal damage? A series of studies with MRI volumetry in adults with partial epilepsy. Progress in brain research. vol 135. 2002-08-22. PMID:12143348.' |
hippocampal sclerosis is found in 60-70% of patients with intractable temporal lobe epilepsy (tle). |
2002-08-22 |
2023-08-12 |
Not clear |
William H Theodore, William D Gaillar. Neuroimaging and the progression of epilepsy. Progress in brain research. vol 135. 2002-08-22. PMID:12143351. |
in patients with temporal lobe epilepsy, structural magnetic resonance imaging (mri) has shown volume reductions ipsilateral to the epileptic focus in hippocampal and extrahippocampal regions; the former, in cross-sectional studies, increase with increasing epilepsy duration. |
2002-08-22 |
2023-08-12 |
human |
S Heckers, C Konrad. Hippocampal neurons in schizophrenia. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 5-6. 2002-08-06. PMID:12111476. |
neuropsychiatric disorders such as temporal lobe epilepsy, amnesia, and the dementias are associated with structural and functional abnormalities of specific hippocampal neurons. |
2002-08-06 |
2023-08-12 |
Not clear |
Carola A Haas, Oliver Dudeck, Matthias Kirsch, Csaba Huszka, Gunda Kann, Stefan Pollak, Josef Zentner, Michael Frotsche. Role for reelin in the development of granule cell dispersion in temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 14. 2002-08-06. PMID:12122039. |
here we show that a decreased expression of reelin mrna by hippocampal cajal-retzius cells correlates with the extent of migration defects in the dentate gyrus of patients with temporal lobe epilepsy. |
2002-08-06 |
2023-08-12 |
Not clear |
Xia Zhang, Shu-Sen Cui, Amy E Wallace, Darren K Hannesson, Larry C Schmued, Deborah M Saucier, William G Honer, Michael E Corcora. Relations between brain pathology and temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 14. 2002-08-06. PMID:12122066. |
temporal lobe epilepsy, the most common type of epilepsy in adult humans, is characterized clinically by the progressive development of spontaneous recurrent seizures of temporal lobe origin and pathologically by hippocampal neuronal loss and mossy fiber sprouting. |
2002-08-06 |
2023-08-12 |
rat |
Regula S Briellmann, Samuel F Berkovic, Ari Syngeniotis, Mark A King, Graeme D Jackso. Seizure-associated hippocampal volume loss: a longitudinal magnetic resonance study of temporal lobe epilepsy. Annals of neurology. vol 51. issue 5. 2002-07-31. PMID:12112114. |
seizure-associated hippocampal volume loss: a longitudinal magnetic resonance study of temporal lobe epilepsy. |
2002-07-31 |
2023-08-12 |
Not clear |
Regula S Briellmann, Samuel F Berkovic, Ari Syngeniotis, Mark A King, Graeme D Jackso. Seizure-associated hippocampal volume loss: a longitudinal magnetic resonance study of temporal lobe epilepsy. Annals of neurology. vol 51. issue 5. 2002-07-31. PMID:12112114. |
this longitudinal quantitative magnetic resonance imaging study of 24 patients with mild temporal lobe epilepsy shows an ipsilateral hippocampal volume decrease of 9% (range, -30 to +0.5%; p = 0.002, paired t test) over a period of 3.5 +/- 0.7 years. |
2002-07-31 |
2023-08-12 |
Not clear |
Kitti Kaiboriboon, R Edward Hoga. Hippocampal shape analysis in status epilepticus associated with acute encephalitis. AJNR. American journal of neuroradiology. vol 23. issue 6. 2002-07-24. PMID:12063233. |
regional volume loss was most accentuated in the medial and lateral aspects of the hippocampal head; the loss was similar to shape changes in hippocampal sclerosis of chronic temporal lobe epilepsy. |
2002-07-24 |
2023-08-12 |
Not clear |
A Djamshidian, R Grassl, M Seltenhammer, T Czech, C Baumgartner, M Schmidbauer, W Ulrich, F Zimpric. Altered expression of voltage-dependent calcium channel alpha(1) subunits in temporal lobe epilepsy with Ammon's horn sclerosis. Neuroscience. vol 111. issue 1. 2002-07-18. PMID:11955712. |
to further characterise their role in temporal lobe epilepsy associated with ammon's horn sclerosis, we investigated the immunohistochemical distribution of five different voltage-dependent calcium channel alpha(1) subunits (alpha(1a), alpha(1b), alpha(1c), alpha(1d), alpha(1e)) in 14 hippocampal specimens of patients with ammon's horn sclerosis in comparison with eight autopsy control cases. |
2002-07-18 |
2023-08-12 |
Not clear |
Kazue Igarashi, Hirokazu Oguni, Makiko Osawa, Yutaka Awaya, Motoichiro Kato, Masaru Mimura, Haruo Kashim. Wisconsin card sorting test in children with temporal lobe epilepsy. Brain & development. vol 24. issue 3. 2002-07-16. PMID:11934515. |
to search for the origin of frontal lobe dysfunction identified by the wisconsin card sorting test (wcst) in temporal lobe epilepsy (tle) patients, we investigated the wcst performance among 19 children with tle (with hippocampal atrophy (ha group n=12), without structural lesions (nsl group n=7)), 15 patients with frontal lobe epilepsy (fle group), and age-matched normal controls (n group). |
2002-07-16 |
2023-08-12 |
Not clear |
S Dupon. [MRI exploration of partial epilepsy]. Revue neurologique. vol 158. issue 5 Pt 2. 2002-07-16. PMID:11997747. |
hippocampal sclerosis is a typical example of an epilepsy-related brain anomaly (mesial temporal lobe epilepsy) whose diagnosis has been changed by mri. |
2002-07-16 |
2023-08-12 |
Not clear |
S Dupon. [MRI exploration of partial epilepsy]. Revue neurologique. vol 158. issue 5 Pt 2. 2002-07-16. PMID:11997747. |
reliable diagnosis of hippocampal sclerosis can now be achieved with mri, contributing to the diagnosis of mesial temporal lobe epilepsy. |
2002-07-16 |
2023-08-12 |
Not clear |
James W Wheless, Howard L Ki. Adolescent seizures and epilepsy syndromes. Epilepsia. vol 43 Suppl 3. 2002-07-12. PMID:12060005. |
finally, although temporal lobe epilepsy associated with hippocampal sclerosis may have its origin in childhood, often the child does not come to surgical evaluation until adolescence or young adulthood. |
2002-07-12 |
2023-08-12 |
Not clear |
James W Wheless, Howard L Ki. Adolescent seizures and epilepsy syndromes. Epilepsia. vol 43 Suppl 3. 2002-07-12. PMID:12060005. |
applying these same criteria to children and adolescents reveals that hippocampal sclerosis is the most common lesion responsible for their intractable temporal lobe epilepsy. |
2002-07-12 |
2023-08-12 |
Not clear |
Paul S Buckmaster, Mary O Smith, Christine L Buckmaster, Richard A LeCouteur, F Edward Dude. Absence of temporal lobe epilepsy pathology in dogs with medically intractable epilepsy. Journal of veterinary internal medicine. vol 16. issue 1. 2002-07-11. PMID:11822812. |
temporal lobe epilepsy is the most common type of epilepsy in adult humans, it is frequently resistant to anticonvulsant therapy, and it is commonly associated with characteristic neuropathological abnormalities in the hippocampal dentate gyrus. |
2002-07-11 |
2023-08-12 |
Not clear |
M Z Gören, F Onat, C Ozkara, E Ozyurt, E Eşkazan, R Ake. GABA and L-glutamic acid release in en bloc resection slices of human hippocampus: an in vitro microdialysis study. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 22. issue 4. 2002-07-08. PMID:11808852. |
microdialysis experiments were performed using the hippocampal head region removed from patients with medically intractable seizures, who underwent surgery for mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs). |
2002-07-08 |
2023-08-12 |
human |
Maria Thom, Sanjay M Sisodiya, Andrew Beckett, Lillian Martinian, Woan-Ru Lin, William Harkness, Tejal N Mitchell, John Craig, John Duncan, Francesco Scaravill. Cytoarchitectural abnormalities in hippocampal sclerosis. Journal of neuropathology and experimental neurology. vol 61. issue 6. 2002-07-08. PMID:12071634. |
hippocampal sclerosis (hs) is the most common pathological substrate for temporal lobe epilepsy with a characteristic pattern of loss of principle neurons primarily in ca1 and hilar subfields. |
2002-07-08 |
2023-08-12 |
human |
F R Tang, W L Lee, T T Ye. Expression of the group I metabotropic glutamate receptor in the hippocampus of patients with mesial temporal lobe epilepsy. Journal of neurocytology. vol 30. issue 5. 2002-07-01. PMID:11951051. |
expression of the group i metabotropic glutamate receptor in the hippocampus of patients with mesial temporal lobe epilepsy. |
2002-07-01 |
2023-08-12 |
Not clear |
F R Tang, W L Lee, T T Ye. Expression of the group I metabotropic glutamate receptor in the hippocampus of patients with mesial temporal lobe epilepsy. Journal of neurocytology. vol 30. issue 5. 2002-07-01. PMID:11951051. |
we postulate that in patients with mesial temporal lobe epilepsy, mglur1 may increase hippocampal excitability through postsynaptic activation, and mglur5 may do so through both pre- and post-synaptic mechanisms. |
2002-07-01 |
2023-08-12 |
Not clear |