| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jerome Engel, Charles Wilson, Anatol Bragi. Advances in understanding the process of epileptogenesis based on patient material: what can the patient tell us? Epilepsia. vol 44 Suppl 12. 2004-02-12. PMID:14641562. |
most current parallel human/animal invasive research has been focused on temporal lobe epilepsy, and particularly that form associated with hippocampal sclerosis, the most common human epileptogenic lesion. |
2004-02-12 |
2023-08-12 |
human |
| Jerome Engel, Charles Wilson, Anatol Bragi. Advances in understanding the process of epileptogenesis based on patient material: what can the patient tell us? Epilepsia. vol 44 Suppl 12. 2004-02-12. PMID:14641562. |
recent in vivo and in vitro parallel, reiterative investigations in patients with mesial temporal lobe epilepsy, and in rats with intrahippocampal kainate-induced hippocampal seizures, have revealed the presence of interictal epileptiform events, termed "fast ripples," which appear to be unique in tissue capable of generating spontaneous seizures. |
2004-02-12 |
2023-08-12 |
human |
| Ognen A C Petroff, Laura D Errante, Jung H Kim, Dennis D Spence. N-acetyl-aspartate, total creatine, and myo-inositol in the epileptogenic human hippocampus. Neurology. vol 60. issue 10. 2004-01-29. PMID:12771256. |
mesial temporal lobe epilepsy (mtle) is characterized by hippocampal atrophy, decreased n-acetyl-aspartate, and a low n-acetyl-aspartate/total creatine ratio, often attributed to neuron loss and gliosis. |
2004-01-29 |
2023-08-12 |
human |
| Gregory Y Chan. Antecedent to hippocampal sclerosis and temporal lobe epilepsy? Neurology. vol 61. issue 11. 2004-01-28. PMID:14663065. |
antecedent to hippocampal sclerosis and temporal lobe epilepsy? |
2004-01-28 |
2023-08-12 |
Not clear |
| Albert J Becker, Jian Chen, Alexander Zien, Dmitry Sochivko, Sabine Normann, Johannes Schramm, Christian E Elger, Otmar D Wiestler, Ingmar Blümck. Correlated stage- and subfield-associated hippocampal gene expression patterns in experimental and human temporal lobe epilepsy. The European journal of neuroscience. vol 18. issue 10. 2004-01-26. PMID:14656328. |
correlated stage- and subfield-associated hippocampal gene expression patterns in experimental and human temporal lobe epilepsy. |
2004-01-26 |
2023-08-12 |
human |
| Albert J Becker, Jian Chen, Alexander Zien, Dmitry Sochivko, Sabine Normann, Johannes Schramm, Christian E Elger, Otmar D Wiestler, Ingmar Blümck. Correlated stage- and subfield-associated hippocampal gene expression patterns in experimental and human temporal lobe epilepsy. The European journal of neuroscience. vol 18. issue 10. 2004-01-26. PMID:14656328. |
a number of genes (n = 18) differentially expressed during the chronic epileptic stage showed corresponding expression patterns in hippocampal subfields of patients with pharmacoresistant temporal lobe epilepsy (n = 5 temporal lobe epilepsy patients; u133a microarrays, affymetrix; covering 22284 human sequences). |
2004-01-26 |
2023-08-12 |
human |
| C Solinas, R S Briellmann, A S Harvey, L A Mitchell, S F Berkovi. Hypertensive encephalopathy: antecedent to hippocampal sclerosis and temporal lobe epilepsy? Neurology. vol 60. issue 9. 2004-01-23. PMID:12743248. |
hypertensive encephalopathy: antecedent to hippocampal sclerosis and temporal lobe epilepsy? |
2004-01-23 |
2023-08-12 |
Not clear |
| Sabine Furtinger, Susanne Pirker, Thomas Czech, Christoph Baumgartner, Günther Sper. Increased expression of gamma-aminobutyric acid type B receptors in the hippocampus of patients with temporal lobe epilepsy. Neuroscience letters. vol 352. issue 2. 2004-01-23. PMID:14625043. |
increased expression of gamma-aminobutyric acid type b receptors in the hippocampus of patients with temporal lobe epilepsy. |
2004-01-23 |
2023-08-12 |
Not clear |
| Sabine Furtinger, Susanne Pirker, Thomas Czech, Christoph Baumgartner, Günther Sper. Increased expression of gamma-aminobutyric acid type B receptors in the hippocampus of patients with temporal lobe epilepsy. Neuroscience letters. vol 352. issue 2. 2004-01-23. PMID:14625043. |
we investigated changes in the mrna expression of the gaba(b) receptor subtypes gaba(b)-r1 and gaba(b)-r2 and of gaba(b) receptor binding in the hippocampus of patients with temporal lobe epilepsy (tle) compared with post-mortem controls. |
2004-01-23 |
2023-08-12 |
Not clear |
| J Zámecník, P Krsek, P Marusic, R Druga, V Benes, M Tichý, V Komáre. [Microscopic disorders of cortical development of the brain and its etiopathogenic importance for detection in patients with temporal epilepsy associated with hippocampal sclerosis]. Ceskoslovenska patologie. vol 39. issue 4. 2004-01-21. PMID:14663930. |
hippocampal sclerosis represents a common structural basis of temporal lobe epilepsy. |
2004-01-21 |
2023-08-12 |
Not clear |
| Mark P Richardson, Bryan A Strange, John S Duncan, Raymond J Dola. Preserved verbal memory function in left medial temporal pathology involves reorganisation of function to right medial temporal lobe. NeuroImage. vol 20 Suppl 1. 2004-01-16. PMID:14597304. |
temporal lobe epilepsy, a common disease, is frequently the consequence of a characteristic hippocampal pathology termed hippocampal sclerosis, which may also affect the amygdala. |
2004-01-16 |
2023-08-12 |
Not clear |
| R Walz, R M R P S Castro, T R Velasco, V Alexandre, M H Lopes, J P Leite, A C Santos, J A Assirati, L Wichert-Ana, V C Terra-Bustamante, M M Bianchin, P C Maciag, K B Ribeiro, R Guarnieri, D Araújo, O Cabalero, R Moura, A C M Salim, K Kindlmann, M C Landemberger, W Marques, R M F Fernandes, L N Serafini, H R Machado, C G Carlotti, R R Brentani, A C Sakamoto, V R Martin. Surgical outcome in mesial temporal sclerosis correlates with prion protein gene variant. Neurology. vol 61. issue 9. 2004-01-14. PMID:14610121. |
mesial temporal lobe epilepsy related to hippocampal sclerosis (mtle-hs) is the most common surgically remediable epileptic syndrome. |
2004-01-14 |
2023-08-12 |
Not clear |
| Andrea Straessle, Fabienne Loup, Dimitrula Arabadzisz, Gordon V Ohning, Jean-Marc Fritsch. Rapid and long-term alterations of hippocampal GABAB receptors in a mouse model of temporal lobe epilepsy. The European journal of neuroscience. vol 18. issue 8. 2003-12-23. PMID:14622182. |
rapid and long-term alterations of hippocampal gabab receptors in a mouse model of temporal lobe epilepsy. |
2003-12-23 |
2023-08-12 |
mouse |
| Stefan Vielhaber, Alexei P Kudin, Tatiana A Kudina, Detlef Stiller, Henning Scheich, Ariel Schoenfeld, Helmut Feistner, Hans-Jochen Heinze, Christian E Elger, Wolfram S Kun. Hippocampal N-acetyl aspartate levels do not mirror neuronal cell densities in creatine-supplemented epileptic rats. The European journal of neuroscience. vol 18. issue 8. 2003-12-23. PMID:14622190. |
here, we used the pilocarpine model of temporal lobe epilepsy to determine whether creatine administration is able to attenuate the epilepsy-associated decrease in hippocampal n-acetyl aspartate (naa) concentrations, impairment of mitochondrial function and neuronal cell loss. |
2003-12-23 |
2023-08-12 |
human |
| En-Ju D Lin, Cristina Richichi, Deborah Young, Kristin Baer, Annamaria Vezzani, Matthew J Durin. Recombinant AAV-mediated expression of galanin in rat hippocampus suppresses seizure development. The European journal of neuroscience. vol 18. issue 7. 2003-12-19. PMID:14622242. |
the seizure suppression effect of galanin expression in the hippocampus by viral vectors may lead to novel therapeutic strategies for the treatment and management of intractable seizures with focal onset such as temporal lobe epilepsy. |
2003-12-19 |
2023-08-12 |
rat |
| L Tebartz van Elst, E S Krishnamoorthy, D Bäumer, C Selai, A von Gunten, N Gene-Cos, D Ebert, M R Trimbl. Psychopathological profile in patients with severe bilateral hippocampal atrophy and temporal lobe epilepsy: evidence in support of the Geschwind syndrome? Epilepsy & behavior : E&B. vol 4. issue 3. 2003-12-05. PMID:12791331. |
psychopathological profile in patients with severe bilateral hippocampal atrophy and temporal lobe epilepsy: evidence in support of the geschwind syndrome? |
2003-12-05 |
2023-08-12 |
Not clear |
| L Tebartz van Elst, E S Krishnamoorthy, D Bäumer, C Selai, A von Gunten, N Gene-Cos, D Ebert, M R Trimbl. Psychopathological profile in patients with severe bilateral hippocampal atrophy and temporal lobe epilepsy: evidence in support of the Geschwind syndrome? Epilepsy & behavior : E&B. vol 4. issue 3. 2003-12-05. PMID:12791331. |
to test the hypothesis that bilateral symmetrical severe volume loss of the hippocampi is of causal relevance to these psychiatric syndromes rather than an epiphenomenon we assessed the psychopathology in a group of patients with temporal lobe epilepsy (tle) and very severe bilateral symmetrical hippocampal atrophy and compared it with that of a patient control group. |
2003-12-05 |
2023-08-12 |
Not clear |
| Hanna B Laurén, Asla Pitkänen, Jari Nissinen, Sanna L Soini, Esa R Korpi, Irma E Holopaine. Selective changes in gamma-aminobutyric acid type A receptor subunits in the hippocampus in spontaneously seizing rats with chronic temporal lobe epilepsy. Neuroscience letters. vol 349. issue 1. 2003-12-04. PMID:12946586. |
selective changes in gamma-aminobutyric acid type a receptor subunits in the hippocampus in spontaneously seizing rats with chronic temporal lobe epilepsy. |
2003-12-04 |
2023-08-12 |
rat |
| Hanna B Laurén, Asla Pitkänen, Jari Nissinen, Sanna L Soini, Esa R Korpi, Irma E Holopaine. Selective changes in gamma-aminobutyric acid type A receptor subunits in the hippocampus in spontaneously seizing rats with chronic temporal lobe epilepsy. Neuroscience letters. vol 349. issue 1. 2003-12-04. PMID:12946586. |
we have used the in situ hybridization technique to study gaba(a) receptor alpha2, alpha4, beta3 and gamma2 subunit mrna expression in the hippocampus of spontaneously seizing rats with chronic temporal lobe epilepsy. |
2003-12-04 |
2023-08-12 |
rat |
| Hanna B Laurén, Asla Pitkänen, Jari Nissinen, Sanna L Soini, Esa R Korpi, Irma E Holopaine. Selective changes in gamma-aminobutyric acid type A receptor subunits in the hippocampus in spontaneously seizing rats with chronic temporal lobe epilepsy. Neuroscience letters. vol 349. issue 1. 2003-12-04. PMID:12946586. |
our results suggest that gaba(a) receptor undergoes region selective subunit changes during epileptogenesis in the hippocampus of rats with chronic temporal lobe epilepsy. |
2003-12-04 |
2023-08-12 |
rat |