All Relations between Epilepsy, Temporal Lobe and dentate gyrus

Publication Sentence Publish Date Extraction Date Species
Antoine D Madar, Jesse A Pfammatter, Jessica Bordenave, Erin I Plumley, Swetha Ravi, Michael Cowie, Eli P Wallace, Bruce P Hermann, Rama K Maganti, Mathew V Jone. Deficits in Behavioral and Neuronal Pattern Separation in Temporal Lobe Epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 46. 2021-11-28. PMID:34620720. in temporal lobe epilepsy, the ability of the dentate gyrus to limit excitatory cortical input to the hippocampus breaks down, leading to seizures. 2021-11-28 2023-08-13 mouse
Catarina Orcinha, Antje Kilias, Enya Paschen, Marie Follo, Carola A Haa. Reelin Is Required for Maintenance of Granule Cell Lamination in the Healthy and Epileptic Hippocampus. Frontiers in molecular neuroscience. vol 14. 2021-09-07. PMID:34483838. one characteristic feature of mesial temporal lobe epilepsy is granule cell dispersion (gcd), a pathological widening of the granule cell layer in the dentate gyrus. 2021-09-07 2023-08-13 mouse
Xin-Li Xiao, Xiao-Lin Wu, Peng-Bo Yang, Hai-Bo Hu, Yu Chen, Min-Li, Kai-Wei Si, Feng Wu, Jian-Xin Li. Status epilepticus induced Gadd45b is required for augmented dentate neurogenesis. Stem cell research. vol 49. 2021-06-21. PMID:33279798. in animal models with temporal lobe epilepsy (tle), the status epilepticus (se) leads to a dramatic increase in number of newly born neuron in the subgranular zone (sgz) of dentate gyrus. 2021-06-21 2023-08-13 mouse
Hajnalka Ábrahám, Judit E Molnár, Noémi Sóki, Csilla Gyimesi, Zsolt Horváth, József Janszky, Tamás Dóczi, László Seres. Etiology-related Degree of Sprouting of Parvalbumin-immunoreactive Axons in the Human Dentate Gyrus in Temporal Lobe Epilepsy. Neuroscience. vol 448. 2021-05-14. PMID:32931846. etiology-related degree of sprouting of parvalbumin-immunoreactive axons in the human dentate gyrus in temporal lobe epilepsy. 2021-05-14 2023-08-13 human
Hajnalka Ábrahám, Judit E Molnár, Noémi Sóki, Csilla Gyimesi, Zsolt Horváth, József Janszky, Tamás Dóczi, László Seres. Etiology-related Degree of Sprouting of Parvalbumin-immunoreactive Axons in the Human Dentate Gyrus in Temporal Lobe Epilepsy. Neuroscience. vol 448. 2021-05-14. PMID:32931846. in the present study, we examined parvalbumin-immunoreactive cells and axons in the dentate gyrus of surgically resected tissues of therapy-resistant temporal lobe epilepsy (tle) patients with different etiologies. 2021-05-14 2023-08-13 human
Stephen Beesley, Thomas Sullenberger, Roshan Ailani, Cameron D'Orio, Mathew S Crockett, Sanjay S Kuma. d-Serine Intervention In The Medial Entorhinal Area Alters TLE-Related Pathology In CA1 Hippocampus Via The Temporoammonic Pathway. Neuroscience. vol 453. 2021-05-14. PMID:33197499. entrainment of the hippocampus by the medial entorhinal area (mea) in temporal lobe epilepsy (tle), the most common type of drug-resistant epilepsy in adults, is believed to be mediated primarily through the perforant pathway (pp), which connects stellate cells in layer (l) ii of the mea with granule cells of the dentate gyrus (dg) to drive the hippocampal tri-synaptic circuit. 2021-05-14 2023-08-13 rat
Ahmad Alhourani, Kenneth N Fish, Thomas A Wozny, Vivek Sudhakar, Ronald L Hamilton, R Mark Richardso. GABA bouton subpopulations in the human dentate gyrus are differentially altered in mesial temporal lobe epilepsy. Journal of neurophysiology. vol 123. issue 1. 2021-05-10. PMID:31800363. gaba bouton subpopulations in the human dentate gyrus are differentially altered in mesial temporal lobe epilepsy. 2021-05-10 2023-08-13 human
Ahmad Alhourani, Kenneth N Fish, Thomas A Wozny, Vivek Sudhakar, Ronald L Hamilton, R Mark Richardso. GABA bouton subpopulations in the human dentate gyrus are differentially altered in mesial temporal lobe epilepsy. Journal of neurophysiology. vol 123. issue 1. 2021-05-10. PMID:31800363. multiple studies have found evidence of abnormal dentate gyrus network circuitry in human mesial temporal lobe epilepsy (mtle). 2021-05-10 2023-08-13 human
Jasmin Weninger, Maurice Meseke, Shaleen Rana, Eckart Förste. Heat-Shock Induces Granule Cell Dispersion and Microgliosis in Hippocampal Slice Cultures. Frontiers in cell and developmental biology. vol 9. 2021-03-12. PMID:33693000. granule cell dispersion (gcd) has been found in the dentate gyrus (dg) of patients with temporal lobe epilepsy (tle) and a history of febrile seizures but was also recently observed in pediatric patients that did not suffer from epilepsy. 2021-03-12 2023-08-13 Not clear
Wenbiao Xiao, Zhiquan Yang, Xiaoxin Yan, Li Feng, Lili Long, Tian Tu, Na Deng, Wenjuan Chen, Bo Xiao, Hongyu Long, Yi Zen. iTRAQ-Based Proteomic Analysis of Dentate Gyrus in Temporal Lobe Epilepsy With Hippocampal Sclerosis. Frontiers in neurology. vol 11. 2021-02-12. PMID:33569037. itraq-based proteomic analysis of dentate gyrus in temporal lobe epilepsy with hippocampal sclerosis. 2021-02-12 2023-08-13 Not clear
Guillermo González-H, Itzel Jatziri Contreras-García, Karla Sánchez-Huerta, Claudio M T Queiroz, Luis Ricardo Gallardo Gudiño, Julieta G Mendoza-Torreblanca, Sergio R Zamudi. Levetiracetam Reduced the Basal Excitability of the Dentate Gyrus without Restoring Impaired Synaptic Plasticity in Rats with Temporal Lobe Epilepsy. Brain sciences. vol 10. issue 9. 2020-10-27. PMID:32933015. levetiracetam reduced the basal excitability of the dentate gyrus without restoring impaired synaptic plasticity in rats with temporal lobe epilepsy. 2020-10-27 2023-08-13 rat
Justin J Botterill, Yi-Ling Lu, John J LaFrancois, Hannah L Bernstein, David Alcantara-Gonzalez, Swati Jain, Paige Leary, Helen E Scharfma. An Excitatory and Epileptogenic Effect of Dentate Gyrus Mossy Cells in a Mouse Model of Epilepsy. Cell reports. vol 29. issue 9. 2020-10-20. PMID:31775052. the sparse activity of hippocampal dentate gyrus (dg) granule cells (gcs) is thought to be critical for cognition and behavior, whereas excessive dg activity may contribute to disorders such as temporal lobe epilepsy (tle). 2020-10-20 2023-08-13 mouse
Esther Krook-Magnuso. The Gate and the Source? The Dentate Gyrus Takes Central Stage in Temporal Lobe Epilepsy. Epilepsy currents. vol 17. issue 1. 2020-10-01. PMID:28331472. the dentate gyrus takes central stage in temporal lobe epilepsy. 2020-10-01 2023-08-13 Not clear
Ji Min Lee, Jungwan Hong, Gyeong Joon Moon, Un Ju Jung, So-Yoon Won, Sang Ryong Ki. Morin Prevents Granule Cell Dispersion and Neurotoxicity Experimental neurobiology. vol 27. issue 3. 2020-10-01. PMID:30022874. morin prevents granule cell dispersion and neurotoxicity an abnormal reorganization of the dentate gyrus and neurotoxic events are important phenotypes in the hippocampus of patients with temporal lobe epilepsy (tle). 2020-10-01 2023-08-13 mouse
Helen E Scharfma. The Dentate Gyrus and Temporal Lobe Epilepsy: An "Exciting" Era. Epilepsy currents. vol 19. issue 4. 2020-10-01. PMID:31232111. the dentate gyrus and temporal lobe epilepsy: an "exciting" era. 2020-10-01 2023-08-13 Not clear
Helen E Scharfma. The Dentate Gyrus and Temporal Lobe Epilepsy: An "Exciting" Era. Epilepsy currents. vol 19. issue 4. 2020-10-01. PMID:31232111. this review describes developments in epilepsy research during the last 3 to 4 decades that focused on the dentate gyrus (dg) and its role in temporal lobe epilepsy (tle). 2020-10-01 2023-08-13 Not clear
Sehwan Kim, Un Ju Jung, Yong-Seok Oh, Min-Tae Jeon, Hyung-Jun Kim, Won-Ho Shin, Jungwan Hong, Sang Ryong Ki. Beneficial Effects of Silibinin Against Kainic Acid-induced Neurotoxicity in the Hippocampus Experimental neurobiology. vol 26. issue 5. 2020-09-30. PMID:29093635. our results indicated that silibinin-treatment could reduce seizure susceptibility and frequency of spontaneous recurrent seizures (srs) induced by ka administration, and attenuate granule cell dispersion (gcd), a morphological alteration characteristic of the dentate gyrus (dg) in temporal lobe epilepsy (tle). 2020-09-30 2023-08-13 mouse
Tao Xu, Xinyuan Yu, Jing Deng, Shu Ou, Xi Liu, Teng Wang, Ying Liu, Juan Yang, Changhong Tan, Jinxian Yuan, Yangmei Che. CXCR7 regulates epileptic seizures by controlling the synaptic activity of hippocampal granule cells. Cell death & disease. vol 10. issue 11. 2020-08-26. PMID:31672961. here, we found that cxcr7 was upregulated in the hippocampal dentate gyrus (dg) of mice subjected to kainic acid (ka)-induced epilepsy and in the brain tissues of patients with temporal lobe epilepsy. 2020-08-26 2023-08-13 mouse
Sergio R Zamudio, Luz A Pichardo-Macías, Verónica Díaz-Villegas, Itzel L Flores-Navarrete, Sonia Guzmán-Velázque. Subchronic cerebrolysin treatment alleviates cognitive impairments and dendritic arborization alterations of granular neurons in the hippocampal dentate gyrus of rats with temporal lobe epilepsy. Epilepsy & behavior : E&B. vol 97. 2020-07-23. PMID:31207446. subchronic cerebrolysin treatment alleviates cognitive impairments and dendritic arborization alterations of granular neurons in the hippocampal dentate gyrus of rats with temporal lobe epilepsy. 2020-07-23 2023-08-13 rat
Jae Young Kwon, Un Ju Jung, Dong Woon Kim, Sehwan Kim, Gyeong Joon Moon, Jungwan Hong, Min-Tae Jeon, Minsang Shin, Jeong Ho Chang, Sang Ryong Ki. Beneficial Effects of Hesperetin in a Mouse Model of Temporal Lobe Epilepsy. Journal of medicinal food. vol 21. issue 12. 2020-05-12. PMID:30136878. abnormal reorganization of the dentate gyrus and neuroinflammation in the hippocampus represent characteristic phenotypes of patients suffering from temporal lobe epilepsy. 2020-05-12 2023-08-13 mouse