| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xu Wang, Chi Ma, Cai-Yun Liu, Guang-Jian Li, Ding Zhao, Dong-Feng Ha. Neuronal NMDAR Currents of the Hippocampus and Learning Performance in Autoimmune Anti-NMDAR Encephalitis and Involvement of TNF-α and IL-6. Frontiers in neurology. vol 10. 2020-10-01. PMID:31297084. |
the purpose of the study examined the effects of pro-inflammatory tumor necrosis factor-α (tnf-α) and interleukin-6 (il-6) on neuronal nmdar currents of the hippocampus in rats with anti-nmdar encephalitis and we further determined the role played by tnf-α and il-6 in modulating learning performance. |
2020-10-01 |
2023-08-13 |
rat |
| Michele Romoli, Paraskevi Krashia, Arjune Sen, Diego Franciotta, Matteo Gastaldi, Annalisa Nobili, Andrea Mancini, Elena Nardi Cesarini, Pasquale Nigro, Nicola Tambasco, Nicola B Mercuri, Lucilla Parnetti, Massimiliano Di Filippo, Marcello D'Amelio, Sarosh R Irani, Cinzia Costa, Paolo Calabres. Hippocampal epileptogenesis in autoimmune encephalitis. Annals of clinical and translational neurology. vol 6. issue 11. 2020-09-21. PMID:31617317. |
hippocampal epileptogenesis in autoimmune encephalitis. |
2020-09-21 |
2023-08-13 |
Not clear |
| Franz Marxreiter, Kathrin Utz, Johannes Carolus Magnus Schlachetzki, Frank Seifert, Manuel Schmidt, Arnd Doerfler, Stefan Schwab, Thomas Schen. Transient naming deficits associated with insular lesions in a patient with encephalitis. Neurocase. vol 25. issue 6. 2020-06-01. PMID:31532322. |
we describe a patient with acute herpes simplex encephalitis with left-hemispheric hippocampal, parahippocampal and insular lesions. |
2020-06-01 |
2023-08-13 |
Not clear |
| Hiroaki Miyahara, Kouki Miyakawa, Haruto Nishida, Shinji Yano, Tomoko Sonoda, So-Ichi Suenobu, Tatsuro Izumi, Tsutomu Daa, Kenji Ihar. Unique cell tropism of HHV-6B in an infantile autopsy case of primary HHV-6B encephalitis. Neuropathology : official journal of the Japanese Society of Neuropathology. 2019-11-20. PMID:29582466. |
human herpes virus 6 (hhv-6) is known to cause primary encephalitis in the frontal lobes/cerebral hemisphere or reactivated encephalitis in the hippocampus, but the pathogenesis remains unclear. |
2019-11-20 |
2023-08-13 |
human |
| Josephine Heine, Harald Prüss, Ute A Kopp, Florian Wegner, Florian Then Bergh, Thomas Münte, Klaus-Peter Wandinger, Friedemann Paul, Thorsten Bartsch, Carsten Fink. Beyond the limbic system: disruption and functional compensation of large-scale brain networks in patients with anti-LGI1 encephalitis. Journal of neurology, neurosurgery, and psychiatry. vol 89. issue 11. 2019-10-03. PMID:29886429. |
hippocampal inflammation in anti-lgi1 encephalitis causes memory deficits, seizures and behavioural abnormalities. |
2019-10-03 |
2023-08-13 |
Not clear |
| Inken Waltl, Christopher Käufer, Sonja Bröer, Chintan Chhatbar, Luca Ghita, Ingo Gerhauser, Muneeb Anjum, Ulrich Kalinke, Wolfgang Lösche. Macrophage depletion by liposome-encapsulated clodronate suppresses seizures but not hippocampal damage after acute viral encephalitis. Neurobiology of disease. vol 110. 2019-09-06. PMID:29208406. |
macrophage depletion by liposome-encapsulated clodronate suppresses seizures but not hippocampal damage after acute viral encephalitis. |
2019-09-06 |
2023-08-13 |
mouse |
| Holger Haselmann, Francesco Mannara, Christian Werner, Jesús Planagumà, Federico Miguez-Cabello, Lars Schmidl, Benedikt Grünewald, Mar Petit-Pedrol, Knut Kirmse, Joseph Classen, Fatih Demir, Nikolaj Klöcker, David Soto, Sören Doose, Josep Dalmau, Stefan Hallermann, Christian Gei. Human Autoantibodies against the AMPA Receptor Subunit GluA2 Induce Receptor Reorganization and Memory Dysfunction. Neuron. vol 100. issue 1. 2019-08-05. PMID:30146304. |
autoantibodies to ampa receptors have been identified in humans with autoimmune encephalitis and severe defects of hippocampal function. |
2019-08-05 |
2023-08-13 |
mouse |
| Zhuangzhuang Chen, Di Zhong, Guozhong L. The role of microglia in viral encephalitis: a review. Journal of neuroinflammation. vol 16. issue 1. 2019-08-05. PMID:30967139. |
on the other hand, microglia mediate presynaptic membrane damage in the hippocampus through complement, resulting in long-term memory impairment and cognitive dysfunction in patients with encephalitis. |
2019-08-05 |
2023-08-13 |
Not clear |
| Annika Hanert, Julius Rave, Oliver Granert, Martin Ziegler, Anya Pedersen, Jan Born, Carsten Finke, Thorsten Bartsc. Hippocampal Dentate Gyrus Atrophy Predicts Pattern Separation Impairment in Patients with LGI1 Encephalitis. Neuroscience. vol 400. 2019-06-21. PMID:30625332. |
hippocampal dentate gyrus atrophy predicts pattern separation impairment in patients with lgi1 encephalitis. |
2019-06-21 |
2023-08-13 |
human |
| Annika Hanert, Julius Rave, Oliver Granert, Martin Ziegler, Anya Pedersen, Jan Born, Carsten Finke, Thorsten Bartsc. Hippocampal Dentate Gyrus Atrophy Predicts Pattern Separation Impairment in Patients with LGI1 Encephalitis. Neuroscience. vol 400. 2019-06-21. PMID:30625332. |
in anti-leucine-rich, glioma-inactivated 1 (lgi1) encephalitis it has been shown in animal models and human imaging studies that hippocampal dg and ca3 are preferentially involved in the pathophysiology process. |
2019-06-21 |
2023-08-13 |
human |
| Annika Hanert, Julius Rave, Oliver Granert, Martin Ziegler, Anya Pedersen, Jan Born, Carsten Finke, Thorsten Bartsc. Hippocampal Dentate Gyrus Atrophy Predicts Pattern Separation Impairment in Patients with LGI1 Encephalitis. Neuroscience. vol 400. 2019-06-21. PMID:30625332. |
thus, in order to elucidate the structure-function relationship and contribution of hippocampal subfields to pattern separation, we examined patients (n = 15, age range: 36-77 years) with the rare lgi1 encephalitis showing lesions to hippocampal subfields. |
2019-06-21 |
2023-08-13 |
human |
| Elane N Magn. Proliferative hippocampal activity in a group of patients with Rasmussen's encephalitis: Neuronal, glial, and BDNF tissue expression correlations. Epilepsy & behavior : E&B. vol 82. 2019-02-21. PMID:29579552. |
proliferative hippocampal activity in a group of patients with rasmussen's encephalitis: neuronal, glial, and bdnf tissue expression correlations. |
2019-02-21 |
2023-08-13 |
human |
| Neşe Ayşit-Altuncu, Canan Ulusoy, Gürkan Öztürk, Erdem Tüzü. Effect of LGI1 antibody-positive IgG on hippocampal neuron survival: a preliminary study. Neuroreport. vol 29. issue 11. 2019-02-20. PMID:29771820. |
many patients with anti-lgi1 encephalitis develop permanent hippocampal neuron loss and chronic neuropsychiatric symptoms, suggesting that lgi antibodies (ab) might have a neurotoxic action. |
2019-02-20 |
2023-08-13 |
mouse |
| Neşe Ayşit-Altuncu, Canan Ulusoy, Gürkan Öztürk, Erdem Tüzü. Effect of LGI1 antibody-positive IgG on hippocampal neuron survival: a preliminary study. Neuroreport. vol 29. issue 11. 2019-02-20. PMID:29771820. |
to investigate this hypothesis, purified serum igg of three patients with anti-lgi1 encephalitis and six healthy controls were incubated with cultured primary hippocampal neurons obtained from newborn mice. |
2019-02-20 |
2023-08-13 |
mouse |
| Christopher Käufer, Chintan Chhatbar, Sonja Bröer, Inken Waltl, Luca Ghita, Ingo Gerhauser, Ulrich Kalinke, Wolfgang Lösche. Chemokine receptors CCR2 and CX3CR1 regulate viral encephalitis-induced hippocampal damage but not seizures. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 38. 2018-10-10. PMID:30181265. |
viral encephalitis is a major risk factor for the development of seizures, epilepsy, and hippocampal damage with associated cognitive impairment, markedly reducing quality of life in survivors. |
2018-10-10 |
2023-08-13 |
Not clear |
| Christopher Käufer, Chintan Chhatbar, Sonja Bröer, Inken Waltl, Luca Ghita, Ingo Gerhauser, Ulrich Kalinke, Wolfgang Lösche. Chemokine receptors CCR2 and CX3CR1 regulate viral encephalitis-induced hippocampal damage but not seizures. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 38. 2018-10-10. PMID:30181265. |
the mechanisms underlying seizures and hippocampal neurodegeneration developing during and after viral encephalitis are only incompletely understood, hampering the development of preventive treatments. |
2018-10-10 |
2023-08-13 |
Not clear |
| Nicola Warren, Theo Theodoros, Stefan Blu. Atypical N-methyl-D-aspartate receptor encephalitis and a hippocampal tumour. The Australian and New Zealand journal of psychiatry. vol 51. issue 4. 2018-08-16. PMID:27670828. |
atypical n-methyl-d-aspartate receptor encephalitis and a hippocampal tumour. |
2018-08-16 |
2023-08-13 |
Not clear |
| Charles L Howe, Reghann G LaFrance-Corey, Emma N Goddery, Renee K Johnson, Kanish Mirchi. Neuronal CCL2 expression drives inflammatory monocyte infiltration into the brain during acute virus infection. Journal of neuroinflammation. vol 14. issue 1. 2018-07-27. PMID:29202854. |
theiler's murine encephalomyelitis virus (tmev) infection of c57bl/6 mice is a model of viral encephalitis in which the compromise results in hippocampal damage and permanent neurological sequelae. |
2018-07-27 |
2023-08-13 |
mouse |
| Stoyan Popkirov, Fatme Seval Ismail, Wenke Grönheit, Monika Kapauer, Jörg Wellmer, Christian G Bie. Progressive hippocampal sclerosis after viral encephalitis: Potential role of NMDA receptor antibodies. Seizure. vol 51. 2018-06-15. PMID:28750305. |
progressive hippocampal sclerosis after viral encephalitis: potential role of nmda receptor antibodies. |
2018-06-15 |
2023-08-13 |
Not clear |
| Stoyan Popkirov, Fatme Seval Ismail, Wenke Grönheit, Monika Kapauer, Jörg Wellmer, Christian G Bie. Progressive hippocampal sclerosis after viral encephalitis: Potential role of NMDA receptor antibodies. Seizure. vol 51. 2018-06-15. PMID:28750305. |
survivors of viral encephalitis can develop refractory epilepsy and hippocampal sclerosis. |
2018-06-15 |
2023-08-13 |
Not clear |