| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G L Almeida, D M Corcos, Z Hasa. Horizontal-plane arm movements with direction reversals performed by normal individuals and individuals with down syndrome. Journal of neurophysiology. vol 84. issue 4. 2000-11-30. PMID:11024088. |
horizontal-plane arm movements with direction reversals performed by normal individuals and individuals with down syndrome. |
2000-11-30 |
2023-08-12 |
human |
| G L Almeida, D M Corcos, Z Hasa. Horizontal-plane arm movements with direction reversals performed by normal individuals and individuals with down syndrome. Journal of neurophysiology. vol 84. issue 4. 2000-11-30. PMID:11024088. |
we examined the systematic variation in shoulder and elbow torque, as well as movement kinematics, for horizontal-plane arm movements with direction reversals performed by normal individuals and individuals with down syndrome. |
2000-11-30 |
2023-08-12 |
human |
| G Barbi, I Kennerknecht, G Wöhr, D Avramopoulos, G Karadima, M B Peterse. Mirror-symmetric duplicated chromosome 21q with minor proximal deletion, and with neocentromere in a child without the classical Down syndrome phenotype. American journal of medical genetics. vol 91. issue 2. 2000-04-21. PMID:10748409. |
although trisomic for almost the entire 21q arm, our patient shows no classical down syndrome phenotype, but only a few minor anomalies found in trisomy 21 and in monosomy of proximal 21q, respectively. |
2000-04-21 |
2023-08-12 |
human |
| P S Ohr, J W Fage. Contingency learning in 9-month-old infants with Down syndrome. American journal of mental retardation : AJMR. vol 99. issue 1. 1994-11-28. PMID:7946255. |
the ability of ten 9-month-old infants with down syndrome to acquire a contingency in which arm movements were reinforced with auditory and visual stimulation was assessed. |
1994-11-28 |
2023-08-12 |
Not clear |
| B L Marrone, E W Campbell, S L Anzick, K Shera, M Campbell, T M Yoshida, M K McCormick, L Deave. Mapping of low-frequency chimeric yeast artificial chromosome libraries from human chromosomes 16 and 21 by fluorescence in situ hybridization and quantitative image analysis. Genomics. vol 21. issue 1. 1994-10-19. PMID:8088788. |
yacs mapped onto chromosome 21 were selected to provide subregional location and ordering of known and unknown markers on the long arm of chromosome 21, particularly in the down syndrome region (q22). |
1994-10-19 |
2023-08-12 |
human |
| G Cadoret, A Beute. Early development of reaching in Down syndrome infants. Early human development. vol 36. issue 3. 1994-09-16. PMID:8062782. |
arm movements were recorded at 5, 7 and 9 months for the control group and 7, 9 and 11 months for the group with down syndrome. |
1994-09-16 |
2023-08-12 |
Not clear |
| G Cadoret, A Beute. Early development of reaching in Down syndrome infants. Early human development. vol 36. issue 3. 1994-09-16. PMID:8062782. |
arm velocity increased significantly with age in the control group, but not in the down syndrome group. |
1994-09-16 |
2023-08-12 |
Not clear |
| G Cadoret, A Beute. Early development of reaching in Down syndrome infants. Early human development. vol 36. issue 3. 1994-09-16. PMID:8062782. |
the deviations from a straight line and the changes in the plane of motion suggest that down syndrome infants have more difficulty in controlling their arm movements. |
1994-09-16 |
2023-08-12 |
Not clear |
| G Annerén, B Edma. Down syndrome--a gene dosage disease caused by trisomy of genes within a small segment of the long arm of chromosome 21, exemplified by the study of effects from the superoxide-dismutase type 1 (SOD-1) gene. APMIS. Supplementum. vol 40. 1994-03-23. PMID:8311993. |
down syndrome--a gene dosage disease caused by trisomy of genes within a small segment of the long arm of chromosome 21, exemplified by the study of effects from the superoxide-dismutase type 1 (sod-1) gene. |
1994-03-23 |
2023-08-12 |
human |
| K H Pitetti, M Climstein, M J Mays, P J Barret. Isokinetic arm and leg strength of adults with Down syndrome: a comparative study. Archives of physical medicine and rehabilitation. vol 73. issue 9. 1992-10-01. PMID:1387522. |
isokinetic arm and leg strength of adults with down syndrome: a comparative study. |
1992-10-01 |
2023-08-11 |
human |
| K H Pitetti, M Climstein, M J Mays, P J Barret. Isokinetic arm and leg strength of adults with Down syndrome: a comparative study. Archives of physical medicine and rehabilitation. vol 73. issue 9. 1992-10-01. PMID:1387522. |
this study compared isokinetic arm (elbow flexion and extension) and leg (knee flexion and extension) strength of individuals with down syndrome (ds), with mental retardation without ds (nds), and sedentary young adults with no mental retardation (nmr). |
1992-10-01 |
2023-08-11 |
human |
| C J Epstei. The consequences of chromosome imbalance. American journal of medical genetics. Supplement. vol 7. 1991-04-16. PMID:2149968. |
therefore, it remains likely that loci present on many parts of the long arm of chromosome 21 play a role in the development of the overall phenotype of down syndrome. |
1991-04-16 |
2023-08-11 |
Not clear |
| Z Rahmani, J L Blouin, N Creau-Goldberg, P C Watkins, J F Mattei, M Poissonnier, M Prieur, Z Chettouh, A Nicole, A Auria. Critical role of the D21S55 region on chromosome 21 in the pathogenesis of Down syndrome. Proceedings of the National Academy of Sciences of the United States of America. vol 86. issue 15. 1989-09-12. PMID:2527368. |
these patients belong to two groups of down syndrome patients characterized by different partial trisomies 21: (i) duplication of the long arm, proximal to 21q22.2, and (ii) duplication of the end of the chromosome, distal to 21q22.2 we assessed the copy number of five chromosome 21 sequences (sod1, d21s17, d21s55, ets2, and d21s15) and found that d21s55 was duplicated in both cases. |
1989-09-12 |
2023-08-11 |
Not clear |
| R L Neve, G D Stewart, P Newcomb, M L Van Keuren, D Patterson, H A Drabkin, D M Kurni. Human chromosome 21-encoded cDNA clones. Gene. vol 49. issue 3. 1987-06-09. PMID:3569920. |
two were localized to the proximal long arm of chromosome 21, two to the distal portion of the long arm, and one to the region of 21q22 implicated in the pathology of down syndrome. |
1987-06-09 |
2023-08-11 |
human |
| C J Epstei. Developmental genetics. Experientia. vol 42. issue 10. 1986-11-26. PMID:3021509. |
all whole arm trisomies and monosomies of the mouse can be produced experimentally, and of special interest is mouse trisomy 16 which has been developed as an animal model of human trisomy 21 (down syndrome). |
1986-11-26 |
2023-08-11 |
mouse |
| H H Kazazian, S E Antonarakis, C Wong, S P Trusko, G Stetten, M Oliver, M J Potter, J F Gusella, P C Watkin. Ring chromosome 21: characterization of DNA sequences at sites of breakage and reunion. Annals of the New York Academy of Sciences. vol 450. 1985-08-06. PMID:3160292. |
since the child lacks the classical phenotype of down syndrome, further studies of the dna distal to the breakpoint on the long arm of chromosome 21 may help us to elucidate "genes" important to the phenotype of down syndrome. |
1985-08-06 |
2023-08-11 |
Not clear |
| S E Antonarakis, S D Kittur, C Metaxotou, P C Watkins, A S Pate. Analysis of DNA haplotypes suggests a genetic predisposition to trisomy 21 associated with DNA sequences on chromosome 21. Proceedings of the National Academy of Sciences of the United States of America. vol 82. issue 10. 1985-06-25. PMID:2987923. |
the chromosomes 21 from 20 greek families with a down syndrome child and 27 control greek families have been examined for dna polymorphism haplotypes by using four common polymorphic sites adjacent to two closely linked single-copy dna sequences (namely pw228c and pw236b), which map somewhere near the proximal long arm of chromosome 21. |
1985-06-25 |
2023-08-11 |
Not clear |
| L Crippa, J Ballaman, E Enge. [Partial trisomy for the segment 21(q11----qter) resulting from a de novo translocation between chromosomes 5 and 21]. Annales de genetique. vol 27. issue 3. 1984-12-26. PMID:6239590. |
a 3 1/2-year-old boy is described whose down syndrome resulted from partial 21 trisomy through unbalanced de novo translocation between the long arm of chromosome 21 and the short arm end of a no. |
1984-12-26 |
2023-08-12 |
Not clear |
| K S Reddy, I M Thomas, H S Narayana. A case of nondisjunction of chromosome 21 (47,X,Yqs,+21) in an Indian family with Yqs. Annales de genetique. vol 27. issue 3. 1984-12-26. PMID:6334487. |
a mentally retarded male with few down syndrome features showed a satellited long arm of y (yqs) and trisomy 21. |
1984-12-26 |
2023-08-12 |
Not clear |
| S A Latt, D M Kurnit, G P Bruns, R R Schreck, C C Morton, L M Kunkel, M Lalande, J Aldridge, R Neve, U Tantravah. Molecular genetic approaches to human diseases involving mental retardation. American journal of mental deficiency. vol 88. issue 5. 1984-07-19. PMID:6731492. |
examples of such diseases include the lesch-nyhan syndrome, phenylketonuria, the fragile x syndrome, down syndrome, and those associated with deletions or duplications of subchromosomal regions, e.g., the proximal short arm of human chromosome #15. |
1984-07-19 |
2023-08-12 |
human |