Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Sandra Scheuer, Marcus Ising, Manfred Uhr, Yvonne Otto, Kai von Klitzing, Annette Maria Klei. FKBP5 polymorphisms moderate the influence of adverse life events on the risk of anxiety and depressive disorders in preschool children. Journal of psychiatric research. vol 72. 2016-09-16. PMID:26521051. |
results indicate that genetic variation in fkbp5 influences the risk of anxiety and/or depressive disorders in preschool age by altering the sensitivity to the deleterious effects of mild to moderate adverse events. |
2016-09-16 |
2023-08-13 |
Not clear |
Sandra Scheuer, Marcus Ising, Manfred Uhr, Yvonne Otto, Kai von Klitzing, Annette Maria Klei. FKBP5 polymorphisms moderate the influence of adverse life events on the risk of anxiety and depressive disorders in preschool children. Journal of psychiatric research. vol 72. 2016-09-16. PMID:26521051. |
fkbp5 polymorphisms moderate the influence of adverse life events on the risk of anxiety and depressive disorders in preschool children. |
2016-09-16 |
2023-08-13 |
Not clear |
Sandra Scheuer, Marcus Ising, Manfred Uhr, Yvonne Otto, Kai von Klitzing, Annette Maria Klei. FKBP5 polymorphisms moderate the influence of adverse life events on the risk of anxiety and depressive disorders in preschool children. Journal of psychiatric research. vol 72. 2016-09-16. PMID:26521051. |
in case of severe life events, the fkbp5 genotype does not seem to play a role, suggesting that severe life events might influence directly the risk of anxiety and/or depressive disorders independent of an fkbp5 genotype-dependent vulnerability. |
2016-09-16 |
2023-08-13 |
Not clear |
Sandra Scheuer, Marcus Ising, Manfred Uhr, Yvonne Otto, Kai von Klitzing, Annette Maria Klei. FKBP5 polymorphisms moderate the influence of adverse life events on the risk of anxiety and depressive disorders in preschool children. Journal of psychiatric research. vol 72. 2016-09-16. PMID:26521051. |
all fkbp5 polymorphisms showed significant interactions with mild to moderate life events, but not with severe life events, in predicting the risk of anxiety and/or depressive disorders (p = 0.003-0.019). |
2016-09-16 |
2023-08-13 |
Not clear |
Aleksandra Szczepankiewicz, Anna Leszczyńska-Rodziewicz, Joanna Pawlak, Beata Narozna, Aleksandra Rajewska-Rager, Monika Wilkosc, Dorota Zaremba, Malgorzata Maciukiewicz, Joanna Twarowska-Hause. FKBP5 polymorphism is associated with major depression but not with bipolar disorder. Journal of affective disorders. vol 164. 2014-10-28. PMID:24856550. |
we hypothesized that genetic variants within the fkbp5 - gene encoding co-chaperone protein essential in gr signaling - may influence the susceptibility to major depressive disorder and bipolar disorder. |
2014-10-28 |
2023-08-13 |
Not clear |
Katarzyna A Ellsworth, Irene Moon, Bruce W Eckloff, Brooke L Fridley, Gregory D Jenkins, Anthony Batzler, Joanna M Biernacka, Ryan Abo, Abra Brisbin, Yuan Ji, Scott Hebbring, Eric D Wieben, David A Mrazek, Richard M Weinshilboum, Liewei Wan. FKBP5 genetic variation: association with selective serotonin reuptake inhibitor treatment outcomes in major depressive disorder. Pharmacogenetics and genomics. vol 23. issue 3. 2013-07-05. PMID:23324805. |
the aim of this study was to comprehensively assess the role of genetic variation in fkbp5, identified by both sanger and next generation dna resequencing, as well as genome-wide single nucleotide polymorphisms (snps) associated with fkbp5 expression in the response to the selective serotonin reuptake inhibitor (ssri) treatment of major depressive disorder. |
2013-07-05 |
2023-08-12 |
Not clear |
Katarzyna A Ellsworth, Irene Moon, Bruce W Eckloff, Brooke L Fridley, Gregory D Jenkins, Anthony Batzler, Joanna M Biernacka, Ryan Abo, Abra Brisbin, Yuan Ji, Scott Hebbring, Eric D Wieben, David A Mrazek, Richard M Weinshilboum, Liewei Wan. FKBP5 genetic variation: association with selective serotonin reuptake inhibitor treatment outcomes in major depressive disorder. Pharmacogenetics and genomics. vol 23. issue 3. 2013-07-05. PMID:23324805. |
fkbp5 genetic variation: association with selective serotonin reuptake inhibitor treatment outcomes in major depressive disorder. |
2013-07-05 |
2023-08-12 |
Not clear |
John C O'Leary, Sheetal Dharia, Laura J Blair, Sarah Brady, Amelia G Johnson, Melinda Peters, Joyce Cheung-Flynn, Marc B Cox, Gabriel de Erausquin, Edwin J Weeber, Umesh K Jinwal, Chad A Dicke. A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51. PloS one. vol 6. issue 9. 2012-02-28. PMID:21935478. |
single nucleotide polymorphisms (snps) in the fkbp5 gene associate with increased recurrence of depressive episodes, increased susceptibility to post-traumatic stress disorder, bipolar disorder, attempt of suicide, and major depressive disorder in hiv patients. |
2012-02-28 |
2023-08-12 |
mouse |
Erick T Tatro, Timothy B Nguyen, Chad A Bousman, Eliezer Masliah, Igor Grant, J Hampton Atkinson, Ian P Everal. Correlation of major depressive disorder symptoms with FKBP5 but not FKBP4 expression in human immunodeficiency virus-infected individuals. Journal of neurovirology. vol 16. issue 5. 2011-02-07. PMID:20726698. |
correlation of major depressive disorder symptoms with fkbp5 but not fkbp4 expression in human immunodeficiency virus-infected individuals. |
2011-02-07 |
2023-08-12 |
human |