All Relations between Depression and prefrontal cortex

Publication Sentence Publish Date Extraction Date Species
Zhimei Niu, Andreana Haley, Alexandra Clark, Audrey Duart. Age exacerbates the negative effect of depression on executive functioning in racial and ethnic minorities. Research square. 2023-12-04. PMID:38045357. collectively, these results suggest that the negative impact of depression on executive functioning and prefrontal cortex volumes integrity may be exacerbated by age and that historically minoritized people may be particularly sensitive to this double jeopardy. 2023-12-04 2023-12-10 human
Robin Fh Cash, Andrew Zalesk. Neuroimaging informed TMS and personalized targeting: evidence, controversies and opportunities. Biological psychiatry. 2023-12-01. PMID:38040047. in this review we outline the motivation for target site personalization, preliminary support (mostly in depression), convergent evidence from other brain stimulation modalities, and generalizability beyond depression and the prefrontal cortex. 2023-12-01 2023-12-10 Not clear
Laith Alexander, Peter C T Hawkins, Jennifer W Evans, Mitul A Mehta, Carlos A Zarat. Preliminary evidence that ketamine alters anterior cingulate resting-state functional connectivity in depressed individuals. Translational psychiatry. vol 13. issue 1. 2023-12-01. PMID:38040678. across cingulate subregions, ketamine differentially modulated rsfc to the right insula and anterior ventromedial prefrontal cortex, compared to placebo, in trd vs. hv; changes to pgacc-insula connectivity correlated with improvements in depression scores. 2023-12-01 2023-12-10 human
C Hacker, M M Mocchi, J Xiao, B A Metzger, J A Adkinson, B R Pascuzzi, R C Mathura, D Oswalt, A Watrous, E Bartoli, A Allawala, V Pirtle, X Fan, I Danstrom, B Shofty, G Banks, Y Zhang, M Armenta-Salas, K Mirpour, N Provenza, S Mathew, J Cohn, D Borton, W Goodman, N Pouratian, S A Sheth, K R Bijank. Aperiodic neural activity is a biomarker for depression severity. medRxiv : the preprint server for health sciences. 2023-11-24. PMID:37986996. the correlation between depression severity scores and aperiodic slope is significant in n=5 subjects, indicating that flatter (less negative) slopes correspond to reduced depression severity, especially in the ventromedial prefrontal cortex. 2023-11-24 2023-11-28 human
Mark C Eldaief, Stephanie McMains, David Izquierdo-Garcia, Mohammad Daneshzand, Aapo Nummenmaa, Rodrigo M Brag. Network-specific metabolic and haemodynamic effects elicited by non-invasive brain stimulation. Nature mental health. vol 1. issue 5. 2023-11-20. PMID:37982031. repetitive transcranial magnetic stimulation (tms), when applied to the dorsolateral prefrontal cortex (dlpfc), treats depression. 2023-11-20 2023-11-29 Not clear
Sabrina K Segal, Charles L Weber, Alexander M Kaplan, Narin Wongngamnit, Aaron G Avallone, Kartiki U Churi, Andrew D Davalt, Christopher G Ivan. Letter to the editor: A novel sequential bilateral neurostimulation approach for treatment-resistant depression involving high-frequency repetitive transcranial magnetic stimulation to the left dorsolateral prefrontal cortex and intermittent theta burst to the right dorsolateral prefrontal cortex. Brain stimulation. 2023-11-19. PMID:37981064. letter to the editor: a novel sequential bilateral neurostimulation approach for treatment-resistant depression involving high-frequency repetitive transcranial magnetic stimulation to the left dorsolateral prefrontal cortex and intermittent theta burst to the right dorsolateral prefrontal cortex. 2023-11-19 2023-11-29 Not clear
Jin Zhang, Weifen Li, Qi Yue, Luping Liu, Sheng-Tao Hou, Jun J. Rapamycin exerts an antidepressant effect and enhances myelination in the prefrontal cortex of chronic restraint stress mice. Neuroscience. 2023-11-05. PMID:37926147. myelination loss was recently found in the prefrontal cortex (pfc) of patients with depression and animal models, but the mechanism of this loss is unclear. 2023-11-05 2023-11-08 mouse
Sebastian Krick, Janusz L Koob, Sylvia Latarnik, Lukas J Volz, Gereon R Fink, Christian Grefkes, Anne K Rehm. Neuroanatomy of post-stroke depression: the association between symptom clusters and lesion location. Brain communications. vol 5. issue 5. 2023-11-01. PMID:37908237. we found that global depression severity, irrespective of individual symptom domains, was primarily linked to right hemispheric lesions in the dorsolateral prefrontal cortex and inferior frontal gyrus. 2023-11-01 2023-11-08 Not clear
Zixuan Ren, Linlin Mu, Lijin Wang, Lingling Xia, Peipei Song, Yan Wang, Junda Li, Fan Duan, Haonan Li, Huajun Tang, Wenjuan Wang, Lin Zhu, Lei Zhang, Xun Song, Yujing Wang, Wei Zhao, Yuqiong Zhu, Ze Wang, Wenyi Shao, Xiaochu Zhang, Dongliang Jia. Predictive role of impulsivity, anxiety, and depression in the efficacy of intermittent theta burst transcranial magnetic stimulation modalities for treating methamphetamine use disorder: A randomized clinical trial. Journal of substance use and addiction treatment. 2023-10-22. PMID:37866441. stimulation of the left dorsolateral prefrontal cortex in mud patients by intermittent theta burst repetitive transcranial magnetic stimulation (itbs-rtms) is effective in reducing cravings, impulsive behavior, anxiety, and depression. 2023-10-22 2023-11-08 Not clear
Lorenzo Lazzerini-Ospri, Jesse J Zhan, Michael B Thomsen, Hui Wang, Fany Messanvi, Johann du Hoffmann, Kevin Cravedi, Ruchi Komal, Yogita Chudasama, Haiqing Zhao, Samer Hatta. Light affects the prefrontal cortex via intrinsically photosensitive retinal ganglion cells. bioRxiv : the preprint server for biology. 2023-10-09. PMID:37808740. the ventromedial prefrontal cortex (vmpfc) is a part of the limbic system engaged in the regulation of social, emotional and cognitive states, which are characteristically impaired in disorders of the brain such as schizophrenia and depression. 2023-10-09 2023-10-15 mouse
Baile Ning, Zhifang Wang, Jiangshan He, Qian Wu, Qiyue Deng, Qing Yang, Jing Gao, Wen Fu, Ying Deng, Bingxin Wu, Xichang Huang, Jilin Mei, Fan Jiang, Wenbin F. The rapid antidepressant effect of acupuncture on two animal models of depression by inhibiting M1-Ach receptors regulates synaptic plasticity in the prefrontal cortex. Brain research. 2023-10-02. PMID:37783259. the rapid antidepressant effect of acupuncture on two animal models of depression by inhibiting m1-ach receptors regulates synaptic plasticity in the prefrontal cortex. 2023-10-02 2023-10-07 Not clear
Marte Christine Ørbo, Ole K Grønli, Camilla Larsen, Torgil R Vangberg, Oddgeir Friborg, Zsolt Turi, Matthias Mittner, Gabor Csifcsak, Per M Aslakse. The antidepressant effect of intermittent theta burst stimulation (iTBS): study protocol for a randomized double-blind sham-controlled trial. Trials. vol 24. issue 1. 2023-10-02. PMID:37784199. intermittent theta burst stimulation (itbs) when applied over the left dorsolateral prefrontal cortex (dlpfc) has been shown to be equally effective and safe to treat depression compared to traditional repetitive transcranial magnetic stimulation (rtms) paradigms. 2023-10-02 2023-10-07 Not clear
Pei Dai, Zhao-Xia Wang, Hui-Xian Yu, Chang-Bin Liu, Si-Hao Liu, Hao Zhan. The Effect of Continuous Theta Burst Stimulation over the Right Dorsolateral Prefrontal Cortex on Cognitive Function and Emotional Regulation in Patients with Cerebral Small Vessel Disease. Brain sciences. vol 13. issue 9. 2023-09-28. PMID:37759910. the purpose of this study was to investigate the effect of continuous theta burst stimulation (ctbs) over the right dorsolateral prefrontal cortex (dlpfc) on the cognitive function and hamilton depression (hamd) scores in patients with csvd. 2023-09-28 2023-10-07 Not clear
Huiqin Wang, Xueying Yang, Huaqing Lai, Yang Sun, Xu Yan, Qidi Ai, Meiyu Lin, Songwei Yang, Yantao Yang, Shifeng Chu, Zhenzhen Wang, Naihong Che. Novel antidepressant mechanism of hypericin: Role of connexin 43-based gap junctions. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 167. 2023-09-21. PMID:37734259. suppression of gap junctions by bilateral injection of carbenoxolone (cbx) in the prefrontal cortex of rats significantly inhibited the restoration of gap junctional dysfunction in depression by hypericin. 2023-09-21 2023-10-07 rat
Anna Alwani, Katarzyna Maziarz, Gabriela Burda, Monika Jankowska-Kiełtyka, Adam Roman, Gabriela Łyszczarz, Safak Er, Justyna Barut, Olga Barczyk-Woźnicka, Elżbieta Pyza, Grzegorz Kreiner, Irena Nalepa, Piotr Chmielar. Investigating the potential effects of α-synuclein aggregation on susceptibility to chronic stress in a mouse Parkinson's disease model. Pharmacological reports : PR. 2023-09-19. PMID:37725330. pd is also associated with the formation of lbs in brain areas responsible for emotional and cognitive regulation such as the amygdala and prefrontal cortex, and concurrent depression prevalence in pd patients. 2023-09-19 2023-10-07 mouse
Ofelia Limón-Morales, Kenia Morales-Quintero, Marcela Arteaga-Silva, Tania Molina-Jiménez, Marco Cerbón, Herlinda Bonilla-Jaim. Alterations of learning and memory are accompanied by alterations in the expression of 5-HT receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male treatment with clomipramine in male rats. Behavioural brain research. 2023-09-15. PMID:37714467. in addition, depression is characterized by a decreased functioning of the serotonergic system due to changes in the activity or expression of its receptors including, most significantly, 5-ht1a, 5-ht2a, and 5-ht3 in brain regions that regulate mood, emotions, and memory, such as the prefrontal cortex, hippocampus, and amygdala. 2023-09-15 2023-10-07 rat
Xiaoxu Fan, Madaline Mocchi, Bailey Pascuzzi, Jiayang Xiao, Brian A Metzger, Raissa K Mathura, Carl Hacker, Joshua A Adkinson, Eleonora Bartoli, Salma Elhassa, Andrew J Watrous, Yue Zhang, Wayne Goodman, Nader Pouratian, Kelly R Bijank. Brain mechanisms underlying the emotion processing bias in treatment-resistant depression. bioRxiv : the preprint server for biology. 2023-09-11. PMID:37693557. here, we had a unique opportunity to record stereotactic electroencephalography (seeg) signals in the amygdala and prefrontal cortex (pfc) from 5 treatment-resistant depression (trd) patients and 12 epilepsy patients (as control) while they participated in an affective bias task in which happy and sad faces were rated. 2023-09-11 2023-10-07 Not clear
S A Codeluppi, M Xu, Y Bansal, A E Lepack, V Duric, M Chow, J Muir, R C Bagot, P Licznerski, S L Wilber, G Sanacora, E Sibille, R S Duman, C Pittenger, M Banas. Prefrontal cortex astroglia modulate anhedonia-like behavior. Molecular psychiatry. 2023-09-11. PMID:37696873. reductions of astroglia expressing glial fibrillary acidic protein (gfap) are consistently found in the prefrontal cortex (pfc) of patients with depression and in rodent chronic stress models. 2023-09-11 2023-10-07 Not clear
Arshad Ghaffari-Nasab, Gonja Javani, Gisou Mohaddes, Mohammad Reza Alipou. Aging impairs recovery from stress-induced depression in male rats possibly by alteration of microRNA-101 expression and Rac1/RhoA pathway in the prefrontal cortex. Biogerontology. 2023-08-29. PMID:37642806. aging impairs recovery from stress-induced depression in male rats possibly by alteration of microrna-101 expression and rac1/rhoa pathway in the prefrontal cortex. 2023-08-29 2023-09-07 rat
Hyunsoo Shin, Hyeonseok Jeong, Wooseok Ryu, Geunhu Lee, Jaeho Lee, Doyu Kim, In-Uk Song, Yong-An Chung, Sungon Le. Robotic transcranial magnetic stimulation in the treatment of depression: a pilot study. Scientific reports. vol 13. issue 1. 2023-08-28. PMID:37640754. the results from clinical and neuroimaging assessments indicated comparable improvements in depression severity and rcbf in the left dorsolateral prefrontal cortex between the robotic and manual rtms groups. 2023-08-28 2023-09-07 Not clear