| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Priyanka Pahwa, Tanveer Singh, Rajesh Kumar Goe. Anticonvulsant Effect of Asparagus racemosus Willd. in a Mouse Model of Catamenial Epilepsy. Neurochemical research. 2021-10-08. PMID:34623565. |
four hours after ptz, animals were assessed for depression like phenotypes followed by euthanasia and separation of brain parts (cortex and hippocampus). |
2021-10-08 |
2023-08-13 |
mouse |
| Agustin Melo-Carrillo, Andrew M Strassman, Aaron J Schain, Ron S Broide, Brian B Cai, Catherine Rhéaume, Amy D Brideau-Andersen, Sait Ashina, Yadira Flores-Montanez, Mitchell F Brin, Rami Burstei. OnabotulinumtoxinA affects cortical recovery period but not occurrence or propagation of cortical spreading depression in rats with compromised blood-brain barrier. Pain. vol 162. issue 9. 2021-09-13. PMID:34448754. |
we report (1) that scalp (head) but not lumbar (back) injections of bont-a shorten the period of profound depression of spontaneous cortical activity that follows a pinprick-induced cortical spreading depression (csd); (2) that neither scalp nor lumbar injections prevent the induction, occurrence, propagation, or spreading velocity of a single wave of csd; (3) that cleaved snap25-one of the most convincing tools to determine the anatomical targeting of bont-a treatment-could easily be detected in pericranial muscles at the injection sites and in nerve fibers of the intracranial dura, but not within any cortical area affected by the csd; (4) that the absence of cleaved snap25 within the cortex and pia is unrelated to whether the blood-brain barrier is intact or compromised; and (5) that bont-a does not alter vascular responses to csd. |
2021-09-13 |
2023-08-13 |
rat |
| Laura E Maglio, José A Noriega-Prieto, Irene B Maroto, Jesús Martin-Cortecero, Antonio Muñoz-Callejas, Marta Callejo-Móstoles, David Fernández de Sevill. IGF-1 facilitates extinction of conditioned fear. eLife. vol 10. 2021-09-10. PMID:33792539. |
here, we show that igf-1 induces a long-lasting depression of the medium and slow post-spike afterhyperpolarization (mahp and sahp), increasing the excitability of layer 5 pyramidal neurons of the rat infralimbic cortex. |
2021-09-10 |
2023-08-13 |
rat |
| Hayrunnisa Bola. Thalamocortical network interruption: A fresh view for migraine symptoms Turkish journal of medical sciences. vol 50. issue SI-2. 2021-08-20. PMID:32421284. |
accordingly, cortical spreading depression (csd), implicated in migraine pathophysiology can be seen as a tool to disconnect thalamocortical network by functionally eliminating cerebral cortex. |
2021-08-20 |
2023-08-13 |
Not clear |
| Tsubasa Takizawa, Cenk Ayata, Shih-Pin Che. Therapeutic implications of cortical spreading depression models in migraine. Progress in brain research. vol 255. 2021-07-28. PMID:33008510. |
cortical spreading depression (csd) is a wave of near-complete depolarization of neurons and glial cells that slowly propagates along the cortex creating the perception of aura. |
2021-07-28 |
2023-08-13 |
Not clear |
| Lukas Frase, Lydia Mertens, Arno Krahl, Kriti Bhatia, Bernd Feige, Sven P Heinrich, Stefan Vestring, Christoph Nissen, Katharina Domschke, Michael Bach, Claus Norman. Transcranial direct current stimulation induces long-term potentiation-like plasticity in the human visual cortex. Translational psychiatry. vol 11. issue 1. 2021-06-18. PMID:33414402. |
the results demonstrate that tdcs can directly induce ltp-like plasticity in the human cortex and suggest a mechanism of action of tdcs relying on the restoration of dysregulated synaptic plasticity in psychiatric disorders such as depression and schizophrenia. |
2021-06-18 |
2023-08-13 |
human |
| Nicholas H Neufeld, Antonia N Kaczkurkin, Aristeidis Sotiras, Benoit H Mulsant, Erin W Dickie, Alastair J Flint, Barnett S Meyers, George S Alexopoulos, Anthony J Rothschild, Ellen M Whyte, Linda Mah, Jay Nierenberg, Matthew J Hoptman, Christos Davatzikos, Theodore D Satterthwaite, Aristotle N Voinesko. Structural brain networks in remitted psychotic depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 7. 2021-05-27. PMID:32109935. |
we compared patients with remitted psychotic depression to healthy controls and found that patients had significantly thinner cortex in five structural covariance networks (insular-limbic, occipito-temporal, temporal, parahippocampal-limbic, and inferior fronto-temporal), confirming our hypothesis that affected brain networks would incorporate cortico-limbic regions. |
2021-05-27 |
2023-08-13 |
human |
| Maria Vomero, Maria Francisca Porto Cruz, Elena Zucchini, Francesca Ciarpella, Emanuela Delfino, Stefano Carli, Christian Boehler, Maria Asplund, Davide Ricci, Luciano Fadiga, Thomas Stieglit. Conformable polyimide-based μECoGs: Bringing the electrodes closer to the signal source. Biomaterials. vol 255. 2021-05-14. PMID:32569863. |
a finite element model was used to quantify the depression of the cortex following the application of devices mechanically above or below conformability threshold. |
2021-05-14 |
2023-08-13 |
rat |
| Vasilios Kafetzopoulos, Nikolaos Kokras, Nuno Sousa, Katerina Antoniou, Ioannis Sotiropoulos, Christina Dall. Nucleus Reuniens Lesion and Antidepressant Treatment Prevent Hippocampal Neurostructural Alterations Induced by Chronic Mild Stress in Male Rats. Neuroscience. vol 454. 2021-05-14. PMID:32828941. |
the hippocampus-prefrontal cortex circuit plays a major role in stress and in the neurobiology of depression and its treatment. |
2021-05-14 |
2023-08-13 |
rat |
| Vasilios Kafetzopoulos, Nikolaos Kokras, Nuno Sousa, Katerina Antoniou, Ioannis Sotiropoulos, Christina Dall. Nucleus Reuniens Lesion and Antidepressant Treatment Prevent Hippocampal Neurostructural Alterations Induced by Chronic Mild Stress in Male Rats. Neuroscience. vol 454. 2021-05-14. PMID:32828941. |
the present findings highlight the importance of hippocampal-prefrontal cortex communication in chronic stress effects on hippocampal neuroplasticity and contribute to the elucidation of the role of re in neurostructural changes underlying stress-driven depression and its treatment. |
2021-05-14 |
2023-08-13 |
rat |
| Yao Wang, Gaoyuan Dong, Limeng Shi, Tianshun Yang, Ruijuan Chen, Huiquan Wang, Guang Ha. Depression of auditory cortex excitability by transcranial alternating current stimulation. Neuroscience letters. vol 742. 2021-04-29. PMID:33359048. |
depression of auditory cortex excitability by transcranial alternating current stimulation. |
2021-04-29 |
2023-08-13 |
human |
| Hidenori Aizawa, Weinan Sun, Kaori Sugiyama, Yukiko Itou, Tomomi Aida, Wanpeng Cui, Saori Toyoda, Haruhi Terai, Michiko Yanagisawa, Kohichi Tanak. Glial glutamate transporter GLT-1 determines susceptibility to spreading depression in the mouse cerebral cortex. Glia. vol 68. issue 12. 2021-04-06. PMID:32585762. |
glial glutamate transporter glt-1 determines susceptibility to spreading depression in the mouse cerebral cortex. |
2021-04-06 |
2023-08-13 |
mouse |
| Sarah Zerimech, Oana Chever, Paolo Scalmani, Lara Pizzamiglio, Fabrice Duprat, Massimo Mantegazz. Cholinergic modulation inhibits cortical spreading depression in mouse neocortex through activation of muscarinic receptors and decreased excitatory/inhibitory drive. Neuropharmacology. vol 166. 2021-04-02. PMID:31945385. |
cortical spreading depression (csd) is a wave of transient network hyperexcitability leading to long lasting depolarization and block of firing, which initiates focally and slowly propagates in the cerebral cortex. |
2021-04-02 |
2023-08-13 |
mouse |
| Bernard J Hanseeuw, Victoria Jonas, Jonathan Jackson, Rebecca A Betensky, Dorene M Rentz, Keith A Johnson, Reisa A Sperling, Nancy J Donova. Association of anxiety with subcortical amyloidosis in cognitively normal older adults. Molecular psychiatry. vol 25. issue 10. 2021-03-31. PMID:30116029. |
higher pib-pet measures in the subcortex (striatum, amygdala, and thalamus), but not in the cortex, were associated with greater anxiety, adjusting for demographics, cognition, and depression. |
2021-03-31 |
2023-08-13 |
human |
| Julia Marie Naman Thomas, Michael Brian Glut. Reconstruction of Mastoid Cortex Defects with Hydroxyapatite Cement for Negative Sequelae of Mastoidectomy. The Annals of otology, rhinology, and laryngology. vol 130. issue 4. 2021-03-18. PMID:32819142. |
mastoid cortex defects resulting from mastoidectomy surgery can rarely lead to negative sequelae, including unsightly post-auricular depression and discomfort. |
2021-03-18 |
2023-08-13 |
Not clear |
| Aaron Tan, Sara Costi, Laurel S Morris, Nicholas T Van Dam, Marin Kautz, Alexis E Whitton, Allyson K Friedman, Katherine A Collins, Gabriella Ahle, Nisha Chadha, Brian Do, Diego A Pizzagalli, Dan V Iosifescu, Eric J Nestler, Ming-Hu Han, James W Murroug. Effects of the KCNQ channel opener ezogabine on functional connectivity of the ventral striatum and clinical symptoms in patients with major depressive disorder. Molecular psychiatry. vol 25. issue 6. 2021-03-09. PMID:30385872. |
improvement in depression was associated with decreased functional connectivity between the ventral caudate and clusters within the mid-cingulate cortex and posterior cingulate cortex (n = 14, voxel-wise p < 0.005). |
2021-03-09 |
2023-08-13 |
human |
| Naijun Yuan, Kairui Tang, Xiaoli Da, Hua Gan, Liangliang He, Xiaojuan Li, Qingyu Ma, Jiaxu Che. Integrating Clinical and Genomic Analyses of Hippocampal-Prefrontal Circuit Disorder in Depression. Frontiers in genetics. vol 11. 2021-02-23. PMID:33613615. |
hippocampus (hip)-prefrontal cortex (pfc) neural circuit abnormalities have been confirmed to exist in mdd; however, the gene-related molecular features of this circuit in the context of depression remain unclear. |
2021-02-23 |
2023-08-13 |
Not clear |
| Azadeh Yazdi, Mohammadmahdi Doostmohammadi, Farshid Pourhossein Majarshin, Siamak Behesht. Betahistine, prevents kindling, ameliorates the behavioral comorbidities and neurodegeneration induced by pentylenetetrazole. Epilepsy & behavior : E&B. vol 105. 2021-01-04. PMID:32062106. |
also, it decreased cell death in the hippocampus and cortex, ameliorated the memory deficit and depression induced by ptz in the kindled animals. |
2021-01-04 |
2023-08-13 |
mouse |
| Nicolas R Bolo, Alan M Jacobson, Gail Musen, Matcheri S Keshavan, Donald C Simonso. Acute Hyperglycemia Increases Brain Pregenual Anterior Cingulate Cortex Glutamate Concentrations in Type 1 Diabetes. Diabetes. vol 69. issue 7. 2020-12-30. PMID:32295804. |
using proton mrs, we measured glutamate concentrations in acc and occipital lobe cortex (occ) in 13 subjects with t1d without major depression (hba |
2020-12-30 |
2023-08-13 |
human |
| Nicholas L Balderston, Camille Roberts, Emily M Beydler, Zhi-De Deng, Thomas Radman, Bruce Luber, Sarah H Lisanby, Monique Ernst, Christian Grillo. A generalized workflow for conducting electric field-optimized, fMRI-guided, transcranial magnetic stimulation. Nature protocols. vol 15. issue 11. 2020-11-27. PMID:33005039. |
transcranial magnetic stimulation (tms) is a noninvasive method to stimulate the cerebral cortex that has applications in psychiatry, such as in the treatment of depression and anxiety. |
2020-11-27 |
2023-08-13 |
human |