| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J R Kelly, M T Crockett, L Alexander, M Haran, A Baker, L Burke, C Brennan, V O'Kean. Psychedelic science in post-COVID-19 psychiatry. Irish journal of psychological medicine. vol 38. issue 2. 2021-06-24. PMID:32811575. |
the compass pathways (compass) phase 2b double-blind trial of psilocybin therapy in antidepressant-free, treatment-resistant depression (trd) is underway to determine the safety, efficacy and optimal dose of psilocybin. |
2021-06-24 |
2023-08-13 |
Not clear |
| N L Mason, K P C Kuypers, F Müller, J Reckweg, D H Y Tse, S W Toennes, N R P W Hutten, J F A Jansen, P Stiers, A Feilding, J G Ramaeker. Me, myself, bye: regional alterations in glutamate and the experience of ego dissolution with psilocybin. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 12. 2021-06-23. PMID:32446245. |
there is growing interest in the therapeutic utility of psychedelic substances, like psilocybin, for disorders characterized by distortions of the self-experience, like depression. |
2021-06-23 |
2023-08-13 |
Not clear |
| Meghan Hibicke, Alexus N Landry, Hannah M Kramer, Zoe K Talman, Charles D Nichol. Psychedelics, but Not Ketamine, Produce Persistent Antidepressant-like Effects in a Rodent Experimental System for the Study of Depression. ACS chemical neuroscience. vol 11. issue 6. 2021-05-24. PMID:32133835. |
psilocybin shows efficacy to alleviate depression in human clinical trials for six or more months after only one or two treatments. |
2021-05-24 |
2023-08-13 |
human |
| Meghan Hibicke, Alexus N Landry, Hannah M Kramer, Zoe K Talman, Charles D Nichol. Psychedelics, but Not Ketamine, Produce Persistent Antidepressant-like Effects in a Rodent Experimental System for the Study of Depression. ACS chemical neuroscience. vol 11. issue 6. 2021-05-24. PMID:32133835. |
to address these questions, we tested psilocybin, lysergic acid diethylamide (lsd), and ketamine in a rat model for depression. |
2021-05-24 |
2023-08-13 |
human |
| Alan K Davis, Frederick S Barrett, Darrick G May, Mary P Cosimano, Nathan D Sepeda, Matthew W Johnson, Patrick H Finan, Roland R Griffith. Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder: A Randomized Clinical Trial. JAMA psychiatry. vol 78. issue 5. 2021-05-06. PMID:33146667. |
recent evidence suggests that 1 or 2 administrations of psilocybin with psychological support produces antidepressant effects in patients with cancer and in those with treatment-resistant depression. |
2021-05-06 |
2023-08-13 |
Not clear |
| Robin Carhart-Harris, Bruna Giribaldi, Rosalind Watts, Michelle Baker-Jones, Ashleigh Murphy-Beiner, Roberta Murphy, Jonny Martell, Allan Blemings, David Erritzoe, David J Nut. Trial of Psilocybin versus Escitalopram for Depression. The New England journal of medicine. vol 384. issue 15. 2021-04-27. PMID:33852780. |
trial of psilocybin versus escitalopram for depression. |
2021-04-27 |
2023-08-13 |
Not clear |
| Robin Carhart-Harris, Bruna Giribaldi, Rosalind Watts, Michelle Baker-Jones, Ashleigh Murphy-Beiner, Roberta Murphy, Jonny Martell, Allan Blemings, David Erritzoe, David J Nut. Trial of Psilocybin versus Escitalopram for Depression. The New England journal of medicine. vol 384. issue 15. 2021-04-27. PMID:33852780. |
psilocybin may have antidepressant properties, but direct comparisons between psilocybin and established treatments for depression are lacking. |
2021-04-27 |
2023-08-13 |
Not clear |
| Stephen Ross, Gabrielle Agin-Liebes, Sharon Lo, Richard J Zeifman, Leila Ghazal, Julia Benville, Silvia Franco Corso, Christian Bjerre Real, Jeffrey Guss, Anthony Bossis, Sarah E Menneng. Acute and Sustained Reductions in Loss of Meaning and Suicidal Ideation Following Psilocybin-Assisted Psychotherapy for Psychiatric and Existential Distress in Life-Threatening Cancer. ACS pharmacology & translational science. vol 4. issue 2. 2021-04-17. PMID:33860185. |
these preliminary results implicate psilocybin treatment as a potentially effective alternative to existing antidepressant medications in patients with cancer that are also suicidal, and warrant further investigation in participants with elevated levels of depression and suicidality. |
2021-04-17 |
2023-08-13 |
human |
| Jose Carlos Bouso, Genís Ona, Rafael G Dos Santos, Jaime E C Halla. Psychedelic Medicines in Major Depression: Progress and Future Challenges. Advances in experimental medicine and biology. vol 1305. 2021-04-12. PMID:33834416. |
partly because of the need of innovative treatments in psychiatry, several studies have assessed the safety and efficacy of drugs like psilocybin or ayahuasca for a wide range of mental disorders, including major depression. |
2021-04-12 |
2023-08-13 |
Not clear |
| Sara J Tai, Elizabeth M Nielson, Molly Lennard-Jones, Riikka-Liisa Johanna Ajantaival, Rachel Winzer, William A Richards, Frederick Reinholdt, Brian D Richards, Peter Gasser, Ekaterina Malievskai. Development and Evaluation of a Therapist Training Program for Psilocybin Therapy for Treatment-Resistant Depression in Clinical Research. Frontiers in psychiatry. vol 12. 2021-03-03. PMID:33643087. |
development and evaluation of a therapist training program for psilocybin therapy for treatment-resistant depression in clinical research. |
2021-03-03 |
2023-08-13 |
Not clear |
| Lea J Mertens, Matthew B Wall, Leor Roseman, Lysia Demetriou, David J Nutt, Robin L Carhart-Harri. Therapeutic mechanisms of psilocybin: Changes in amygdala and prefrontal functional connectivity during emotional processing after psilocybin for treatment-resistant depression. Journal of psychopharmacology (Oxford, England). vol 34. issue 2. 2021-01-11. PMID:31941394. |
therapeutic mechanisms of psilocybin: changes in amygdala and prefrontal functional connectivity during emotional processing after psilocybin for treatment-resistant depression. |
2021-01-11 |
2023-08-13 |
Not clear |
| Lea J Mertens, Matthew B Wall, Leor Roseman, Lysia Demetriou, David J Nutt, Robin L Carhart-Harri. Therapeutic mechanisms of psilocybin: Changes in amygdala and prefrontal functional connectivity during emotional processing after psilocybin for treatment-resistant depression. Journal of psychopharmacology (Oxford, England). vol 34. issue 2. 2021-01-11. PMID:31941394. |
psilocybin has shown promise as a treatment for depression but its therapeutic mechanisms are not properly understood. |
2021-01-11 |
2023-08-13 |
Not clear |
| Ana Sofia Vargas, Ângelo Luís, Mário Barroso, Eugenia Gallardo, Luísa Pereir. Psilocybin as a New Approach to Treat Depression and Anxiety in the Context of Life-Threatening Diseases-A Systematic Review and Meta-Analysis of Clinical Trials. Biomedicines. vol 8. issue 9. 2020-10-20. PMID:32899469. |
psilocybin as a new approach to treat depression and anxiety in the context of life-threatening diseases-a systematic review and meta-analysis of clinical trials. |
2020-10-20 |
2023-08-13 |
Not clear |
| Ana Sofia Vargas, Ângelo Luís, Mário Barroso, Eugenia Gallardo, Luísa Pereir. Psilocybin as a New Approach to Treat Depression and Anxiety in the Context of Life-Threatening Diseases-A Systematic Review and Meta-Analysis of Clinical Trials. Biomedicines. vol 8. issue 9. 2020-10-20. PMID:32899469. |
recent research indicates that psilocybin may constitute a valid approach to treat depression and anxiety associated to life-threatening diseases. |
2020-10-20 |
2023-08-13 |
Not clear |
| David Nutt, David Erritzoe, Robin Carhart-Harri. Psychedelic Psychiatry's Brave New World. Cell. vol 181. issue 1. 2020-10-16. PMID:32243793. |
outcomes of neuroscience and clinical research into 5-hydroxytryptamine 2a (5-ht2a) receptor agonists, such as psilocybin, show promise for addressing a range of serious disorders, including depression and addiction. |
2020-10-16 |
2023-08-13 |
Not clear |
| Ananya Mahapatra, Rishi Gupt. Role of psilocybin in the treatment of depression. Therapeutic advances in psychopharmacology. vol 7. issue 1. 2020-10-01. PMID:28101325. |
role of psilocybin in the treatment of depression. |
2020-10-01 |
2023-08-13 |
Not clear |
| Tara C Malone, Sarah E Mennenga, Jeffrey Guss, Samantha K Podrebarac, Lindsey T Owens, Anthony P Bossis, Alexander B Belser, Gabrielle Agin-Liebes, Michael P Bogenschutz, Stephen Ros. Individual Experiences in Four Cancer Patients Following Psilocybin-Assisted Psychotherapy. Frontiers in pharmacology. vol 9. 2020-10-01. PMID:29666578. |
a double-blind controlled trial was performed, where 29 patients with cancer-related anxiety and depression were randomly assigned to treatment with single-dose psilocybin (0.3 mg/kg) or niacin in conjunction with psychotherapy. |
2020-10-01 |
2023-08-13 |
human |
| Taylor Lyons, Robin Lester Carhart-Harri. More Realistic Forecasting of Future Life Events After Psilocybin for Treatment-Resistant Depression. Frontiers in psychology. vol 9. 2020-10-01. PMID:30369890. |
more realistic forecasting of future life events after psilocybin for treatment-resistant depression. |
2020-10-01 |
2023-08-13 |
Not clear |
| Leor Roseman, David J Nutt, Robin L Carhart-Harri. Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression. Frontiers in pharmacology. vol 8. 2020-09-29. PMID:29387009. |
quality of acute psychedelic experience predicts therapeutic efficacy of psilocybin for treatment-resistant depression. |
2020-09-29 |
2023-08-13 |
Not clear |
| Kristin Heuschkel, Kim P C Kuyper. Depression, Mindfulness, and Psilocybin: Possible Complementary Effects of Mindfulness Meditation and Psilocybin in the Treatment of Depression. A Review. Frontiers in psychiatry. vol 11. 2020-09-28. PMID:32296353. |
depression, mindfulness, and psilocybin: possible complementary effects of mindfulness meditation and psilocybin in the treatment of depression. |
2020-09-28 |
2023-08-13 |
Not clear |