| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ida Kupcova, Lubos Danisovic, Sona Bernatova, Stefan Harsany. Analysis of Salivary Neuropeptides in Anxiety and Depression Using the Luminex MAGPIX® System. Cureus. vol 16. issue 8. 2024-09-30. PMID:39347144. |
anxiety and depressive disorders are highly prevalent mental health conditions, affecting millions worldwide. advancements in neurobiology have identified the effects of various neuropeptides in modulating mood and stress responses. some of the well-researched neuropeptides in plasma are oxytocin (oxt), alpha-melanocyte-stimulating hormone (alpha-msh), beta-endorphin, neurotensin, and substance p. in this study, we used methods of liquid biopsy to acquire saliva samples to analyze the concentrations of neuropeptides associated with depression. |
2024-09-30 |
2024-10-02 |
Not clear |
| Sophie Béraud-Dufour, Chistelle Devader, Fabienne Massa, Morgane Roulot, Thierry Coppola, Jean Mazell. Focal Adhesion Kinase-Dependent Role of the Soluble Form of Neurotensin Receptor-3/Sortilin in Colorectal Cancer Cell Dissociation. International journal of molecular sciences. vol 17. issue 11. 2017-03-30. PMID:27834811. |
the aim of the present review is to unravel the mechanisms of action of the soluble form of the neurotensin (nt) receptor-3 (ntsr3), also called sortilin, in numerous physiopathological processes including cancer development, cardiovascular diseases and depression. |
2017-03-30 |
2023-08-13 |
Not clear |
| Elisabeth Piccart, Nicholas A Courtney, Sarah Y Branch, Christopher P Ford, Michael J Beckstea. Neurotensin Induces Presynaptic Depression of D2 Dopamine Autoreceptor-Mediated Neurotransmission in Midbrain Dopaminergic Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 31. 2015-11-05. PMID:26245975. |
neurotensin induces presynaptic depression of d2 dopamine autoreceptor-mediated neurotransmission in midbrain dopaminergic neurons. |
2015-11-05 |
2023-08-13 |
mouse |
| Jean Costenti. [The importance of in vivo pharmacology in fundamental research on psychotropic drugs and their biological targets]. Therapie. vol 59. issue 1. 2004-07-21. PMID:15199668. |
each one of these approaches has been illustrated by an example developed within the rouen neuropsychopharmacology unit: the psychobehavioural spectrum of mice with invalidation of the gene coding for adenosine a2a receptors; the abolition of either nociceptin orl1 receptors or neurotensin ntr2 receptors in order to characterise their functions; the concentration, by controlled breeding in mice, of a phenotype corresponding to that of depression. |
2004-07-21 |
2023-08-12 |
mouse |
| b' A A Math\\xc3\\xa. Neuropeptides and electroconvulsive treatment. The journal of ECT. vol 15. issue 1. 1999-06-01. PMID:10189619.' |
neuropeptides: corticotropin releasing factor (crf), neuropeptide y (npy) and somatostatin (sts) have been associated with depression and anxiety, while neurotensin (nt), calcitonin gene-related peptide (cgrp) and tachykinins [neurokinin a (nka) and substance p (sp)] are presumed to also play a role in the function of the dopaminergic system. |
1999-06-01 |
2023-08-12 |
human |
| A A Mathé, P A Jimenez, E Theodorsson, C Stenfor. Neuropeptide Y, neurokinin A and neurotensin in brain regions of Fawn Hooded "depressed", Wistar, and Sprague Dawley rats. Effects of electroconvulsive stimuli. Progress in neuro-psychopharmacology & biological psychiatry. vol 22. issue 3. 1998-08-31. PMID:9612849. |
concentrations of neuropeptide y (npy)-, neurokinin a (nka)- and neurotensin (nt)-like immunoreactivity (-li) were measured in brain tissues of fawn hooded (fh) (a model of depression), wistar (w) (control for depression) and sprague dawley (sd) rats (control for strain) with the aim to explore possible associations between neuropeptides and models of depression. |
1998-08-31 |
2023-08-12 |
rat |
| T M Saleh, S B Kombian, J A Zidichouski, Q J Pittma. Cholecystokinin and neurotensin inversely modulate excitatory synaptic transmission in the parabrachial nucleus in vitro. Neuroscience. vol 77. issue 1. 1997-05-02. PMID:9044371. |
paired-pulse depression was also enhanced and decreased by neurotensin and cholecystokinin, respectively. |
1997-05-02 |
2023-08-12 |
rat |
| L Cervo, C Rossi, E Tatarczynska, R Samani. Antidepressant-like effect of neurotensin administered in the ventral tegmental area in the forced swimming test. Psychopharmacology. vol 109. issue 3. 1995-02-14. PMID:1365637. |
the significance of these findings for a role of endogenous neurotensin in depression remains to be clarified. |
1995-02-14 |
2023-08-11 |
rat |
| C B Nemeroff, G Bissett. Involvement of non-opioid peptides in the pathogenesis of neurological and psychiatric disorders: evidence from CSF and post-mortem studies. Progress in clinical and biological research. vol 192. 1986-02-07. PMID:2934745. |
although much attention has been focused on the opioid peptides, substantial data strongly support the hypothesis that non-opioid peptides such as somatostatin, neurotensin and substance p are altered in a diverse number of neuropsychiatric disorders including alzheimer's disease, huntington's chorea, parkinson's disease, major depression and schizophrenia. |
1986-02-07 |
2023-08-11 |
Not clear |
| A Pazos, M López, J Flóre. Different mechanisms are involved in the respiratory depression and analgesia induced by neurotensin in rats. European journal of pharmacology. vol 98. issue 1. 1984-06-06. PMID:6714297. |
different mechanisms are involved in the respiratory depression and analgesia induced by neurotensin in rats. |
1984-06-06 |
2023-08-12 |
rat |
| J A Biggins, E K Perry, J R McDermott, A I Smith, R H Perry, J A Edwardso. Post mortem levels of thyrotropin-releasing hormone and neurotensin in the amygdala in Alzheimer's disease, schizophrenia and depression. Journal of the neurological sciences. vol 58. issue 1. 1983-06-10. PMID:6405015. |
the levels of neurotensin and thyrotropin-releasing hormone (trh) in normal post mortem human amygdala have been compared with those in cases of schizophrenia, alzheimer's disease and depression. |
1983-06-10 |
2023-08-12 |
human |
| J A Biggins, E K Perry, J R McDermott, A I Smith, R H Perry, J A Edwardso. Post mortem levels of thyrotropin-releasing hormone and neurotensin in the amygdala in Alzheimer's disease, schizophrenia and depression. Journal of the neurological sciences. vol 58. issue 1. 1983-06-10. PMID:6405015. |
post mortem levels of thyrotropin-releasing hormone and neurotensin in the amygdala in alzheimer's disease, schizophrenia and depression. |
1983-06-10 |
2023-08-12 |
human |