| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Leonardo Afonso Dos Santos, Eric Cretaz, Helena Bellini, Adriana Munhoz Carneiro, José Gallucci-Neto, Leda Leme Tallib, André Russowsky Brunon. No changes in plasma Brain-Derived Neurotrophic Factor (BDNF) levels in Treatment-Resistant Depression patients submitted to Convulsive Therapies. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). 2025-03-16. PMID:40089989. |
no changes in plasma brain-derived neurotrophic factor (bdnf) levels in treatment-resistant depression patients submitted to convulsive therapies. |
2025-03-16 |
2025-03-19 |
Not clear |
| Unai Sarriés-Serrano, Lluis Miquel-Rio, Noemí Santana, Verónica Paz, María Sancho-Alonso, Luis F Callado, J Javier Meana, Analia Bortolozz. Impaired unfolded protein response, BDNF and synuclein markers in postmortem dorsolateral prefrontal cortex and caudate nucleus of patients with depression and Parkinson's disease. Progress in neuro-psychopharmacology & biological psychiatry. 2025-02-27. PMID:40015617. |
impaired unfolded protein response, bdnf and synuclein markers in postmortem dorsolateral prefrontal cortex and caudate nucleus of patients with depression and parkinson's disease. |
2025-02-27 |
2025-03-02 |
Not clear |
| Brenda Viridiana Rabago-Barajas, Miguel Ángel Macías-Islas, Ana Miriam Saldaña-Cruz, Jesús Emmanuel Arana-Yepez, Eva Maria Olivas-Flores, Adriana Aguayo-Areli. Association of the Val66Met Polymorphism of the BDNF Gene with the Depression in a Mexican Population with Multiple Sclerosis. Life (Basel, Switzerland). vol 15. issue 2. 2025-02-26. PMID:40003622. |
association of the val66met polymorphism of the bdnf gene with the depression in a mexican population with multiple sclerosis. |
2025-02-26 |
2025-02-28 |
Not clear |
| Vijay Kumar, Gaurav Dosh. Investigating the antidepressant effects of amantadine combined with amitriptyline in a chronic unpredictable mild stress model in mice. Neuroscience letters. 2025-02-21. PMID:39983862. |
bdnf is crucial for neuroplasticity, synaptic regulation, and neuronal survival and its reduced level is linked to the development of depression. |
2025-02-21 |
2025-02-24 |
mouse |
| Long Li, Jin Wang, Shanbo Ma, Meiling Zheng, Feiyan Wang, Xiaodi Guo, Shan Miao, Xiaopeng Sh. Pharmacological mechanism of Shaoyao Gancao Decoction in the treatment of depression based on bioinformatics and animal experiment. Heliyon. vol 10. issue 15. 2025-02-17. PMID:39959777. |
through the production of lps depression model mice, drug treatment, behavioral test and hippocampal tissue sample detection, it was found that shaoyao gancao decoction can regulate the levels of il-10, tnf- α, bdnf, smad3, fgfr1 and fgfr2 to improve depression, which can provide a theoretical basis for exploring the efficacy of shaoyao gancao decoction in the treatment of depression. |
2025-02-17 |
2025-02-23 |
mouse |
| Weronika Zwolińska, Karolina Bilska, Maria Skibińska, Natalia Pytlińska, Agnieszka Słopień, Monika Dmitrzak-Węglar. BDNF and proBDNF serum levels during antidepressant treatment in adolescent girls with a first-lifetime episode of depression: A prospective case-controlled study. Journal of affective disorders. 2025-02-17. PMID:39961447. |
bdnf and probdnf serum levels during antidepressant treatment in adolescent girls with a first-lifetime episode of depression: a prospective case-controlled study. |
2025-02-17 |
2025-02-23 |
human |
| Weronika Zwolińska, Karolina Bilska, Maria Skibińska, Natalia Pytlińska, Agnieszka Słopień, Monika Dmitrzak-Węglar. BDNF and proBDNF serum levels during antidepressant treatment in adolescent girls with a first-lifetime episode of depression: A prospective case-controlled study. Journal of affective disorders. 2025-02-17. PMID:39961447. |
as one of the most promising biomarkers in depression course and treatment, the brain-derived neurotrophic factor (bdnf) has been identified as a possible predictor of antidepressant treatment outcomes in the adult population. |
2025-02-17 |
2025-02-23 |
human |
| Eli-Eelika Esvald, Andra Moistus, Karin Lehe, Annela Avarlaid, Anastassia Šubina, Liis Kuusemets, Jürgen Tuvikene, Tõnis Timmus. Stimulus-dependent expression of The Journal of neuroscience : the official journal of the Society for Neuroscience. 2025-02-13. PMID:39947922. |
an imbalance in bdnf levels can lead to a wide range of diseases, including depression and neurodevelopmental disorders. |
2025-02-13 |
2025-02-16 |
Not clear |
| Samantha Timoteo Oliveira da Fonseca, Cláudia Cristina Alves, Clarissa Tavares Dias, Cristiano Mendes-da-Silv. Probiotics and undernourishment impact on brain 5-Hydroxytryptamine system and neurotrophin BDNF in rats: Risk of depression and anxiety? Nutrition (Burbank, Los Angeles County, Calif.). vol 132. 2025-02-04. PMID:39904121. |
probiotics and undernourishment impact on brain 5-hydroxytryptamine system and neurotrophin bdnf in rats: risk of depression and anxiety? |
2025-02-04 |
2025-02-07 |
rat |
| Gilberto Uriel Rosas-Sánchez, León Jesús Germán-Ponciano, Gabriel Guillen-Ruiz, Jonathan Cueto-Escobedo, Ana Karen Limón-Vázquez, Juan Francisco Rodríguez-Landa, César Soria-Fregoz. Neuroplasticity and Mechanisms of Action of Acute and Chronic Treatment with Antidepressants in Preclinical Studies. Biomedicines. vol 12. issue 12. 2025-01-14. PMID:39767650. |
antidepressants increase the synaptic availability of monoamines (monoaminergic hypothesis) such as 5-ht, na, and gamma-aminobutyric acid (gaba) by inhibiting their reuptake or degradation and activating intracellular signaling pathways such as the responsive element binding protein (camp-creb) cascade, which regulates the expression of genes related to neuroplasticity and neurogenesis, such as brain-derived neurotrophic factor (bdnf), in various brain structures implicated in depression. |
2025-01-14 |
2025-01-16 |
Not clear |
| Amine Bahi, Jean-Luc Dreye. Hippocampal Viral-Mediated Urokinase Plasminogen Activator (uPA) Overexpression Mitigates Stress-Induced Anxiety and Depression in Rats by Increasing Brain-Derived Neurotrophic Factor (BDNF) Levels. Biomolecules. vol 14. issue 12. 2025-01-08. PMID:39766310. |
hippocampal viral-mediated urokinase plasminogen activator (upa) overexpression mitigates stress-induced anxiety and depression in rats by increasing brain-derived neurotrophic factor (bdnf) levels. |
2025-01-08 |
2025-01-13 |
rat |
| Dawood Hossaini, Adam Khan Alipour, Meysam Sajjadi, Mustafa Ansari, Murtaza Haidar. Biotin Mitigates Alcohol Withdrawal-Induced Anxiety and Depression by Regulating Serotonin Metabolism, BDNF, Inflammation, and Oxidative Stress in Rats. Neuropsychopharmacology reports. vol 45. issue 1. 2025-01-04. PMID:39754400. |
biotin mitigates alcohol withdrawal-induced anxiety and depression by regulating serotonin metabolism, bdnf, inflammation, and oxidative stress in rats. |
2025-01-04 |
2025-01-08 |
rat |
| Simone Pardossi, Andrea Fagiolini, Alessandro Cuom. Variations in BDNF and Their Role in the Neurotrophic Antidepressant Mechanisms of Ketamine and Esketamine: A Review. International journal of molecular sciences. vol 25. issue 23. 2024-12-17. PMID:39684808. |
currently, the limited number of studies suggests the need for further research, including larger sample sizes and investigations of bdnf and intranasal esketamine, which has been approved by several regulatory agencies for the treatment of treatment-resistant depression. |
2024-12-17 |
2024-12-21 |
human |
| Yuchen Fan, Xinchi Luan, Xuezhe Wang, Hongchi Li, Hongjiao Zhao, Sheng Li, Xiaoxuan Li, Zhenkang Qi. Exploring the Association between BDNF related Signaling Pathways and Depression: A Literature Review. Brain research bulletin. 2024-11-28. PMID:39608613. |
exploring the association between bdnf related signaling pathways and depression: a literature review. |
2024-11-28 |
2024-12-01 |
Not clear |
| Yuchen Fan, Xinchi Luan, Xuezhe Wang, Hongchi Li, Hongjiao Zhao, Sheng Li, Xiaoxuan Li, Zhenkang Qi. Exploring the Association between BDNF related Signaling Pathways and Depression: A Literature Review. Brain research bulletin. 2024-11-28. PMID:39608613. |
at present, the pathogenesis of multiple depression is not fully clear, but its occurrence can be related to biological or environmental pathways, among which brain-derived neurotrophic factor (bdnf) can unequivocally act on two downstream receptors, tyrosine kinase receptor (trkb) and the p75 neurotrophin receptor (p75ntr), then affect the related signal pathways, affecting the occurrence and development of depression. |
2024-11-28 |
2024-12-01 |
Not clear |
| Yuchen Fan, Xinchi Luan, Xuezhe Wang, Hongchi Li, Hongjiao Zhao, Sheng Li, Xiaoxuan Li, Zhenkang Qi. Exploring the Association between BDNF related Signaling Pathways and Depression: A Literature Review. Brain research bulletin. 2024-11-28. PMID:39608613. |
in this review, we mainly summarized the signaling pathways associated with bdnf and classified them according to different receptors and related molecules, providing promising insights and future directions in the treatment of depression. |
2024-11-28 |
2024-12-01 |
Not clear |
| Zhuohang Xian, Liangjing Tian, Zhixuan Yao, Lei Cao, Zhilin Jia, Gangqin L. Mechanism of N6-Methyladenosine Modification in the Pathogenesis of Depression. Molecular neurobiology. 2024-11-17. PMID:39551913. |
in this review, we describe the underlying molecular mechanisms between m6a and depression from several aspects including inflammation, stress, neuroplasticity including neurogenesis, and brain structure, which contain the interactions of m6a with cytokines, the hpa axis, bdnf, and other biological molecules or mechanisms in detail. |
2024-11-17 |
2024-11-22 |
Not clear |
| Luisa Maria Rivera, Glorieuse Uwizeye, Hannah Stolrow, Brock Christensen, Julienne Rutherford, Zaneta Thaye. Prenatal exposure to genocide and subsequent adverse childhood events are associated with DNA methylation of SLC6A4, BDNF, and PRDM8 in early adulthood in Rwanda. Scientific reports. vol 14. issue 1. 2024-11-13. PMID:39537739. |
methylation in bdnf and slc6a4 correlated with depression and anxiety symptoms. |
2024-11-13 |
2024-11-17 |
Not clear |
| Cong-Ya Chen, Yu-Fei Wang, Lan Lei, Yi Zhan. MicroRNA-specific targets for neuronal plasticity, neurotransmitters, neurotrophic factors, and gut microbes in the pathogenesis and therapeutics of depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 136. 2024-11-12. PMID:39521033. |
conclusively, mirnas are involved in the pathology of depression by causing structural and functional changes in synapses, mediating neuronal regeneration, differentiation, and apoptosis, regulating the gut microbes and the expression of various neurotransmitters and bdnf, and mediating inflammatory and immune responses. |
2024-11-12 |
2024-11-17 |
Not clear |
| Celeste Yin-Chieh Wu, Yulan Zhang, Peyton Howard, Fang Huang, Reggie Hui-Chao Le. ACSL3 is a promising therapeutic target for alleviating anxiety and depression in Alzheimer's disease. GeroScience. 2024-11-12. PMID:39532829. |
upregulation of acsl3 via adenovirus in aged 3xtg-ad mice led to increased protein levels of brain-derived neurotrophic factor (bdnf) and vascular endothelial growth factor c (vegf-c) (via brain histology, capillary-based immunoassay), resulting in alleviation of depression and anxiety symptoms. |
2024-11-12 |
2024-11-17 |
mouse |