| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hayrunnisa Bolay, Doga Vuralli, Peter J Goadsb. Aura and Head pain: relationship and gaps in the translational models. The journal of headache and pain. vol 20. issue 1. 2020-01-07. PMID:31481015. |
cortical spreading depression (csd) is recognized as the biological substrate of migraine aura and experimental animal studies have provided mechanisms that possibly link csd to the activation of trigeminal neurons mediating lateralized head pain. |
2020-01-07 |
2023-08-13 |
human |
| Mieko Sugiura, Koichi Shibata, Satoshi Saito, Yoshiko Nishimura, Koichi Takahashi, Hiroshi Sakur. [A case of spontaneous intracranial hypotension with transient neurological symptoms]. Rinsho shinkeigaku = Clinical neurology. vol 59. issue 8. 2019-12-16. PMID:31341129. |
the repeated transient neurologic symptoms suggesting migraine aura may have originated from csah, which in turn led to cortical spreading depression. |
2019-12-16 |
2023-08-13 |
Not clear |
| Alan J McComas, Adrian R M Upto. Transcranial Magnetic Stimulation in Migraine: A New Therapy and New Insights into Pathogenesis. Critical reviews in biomedical engineering. vol 44. issue 5. 2019-11-20. PMID:29199598. |
in relation to the pathogenesis of migraine, the prompt relief of symptoms often observed with tms is considered incompatible with an underlying neuroinflammatory process and with spreading depression as a cause of aura. |
2019-11-20 |
2023-08-13 |
Not clear |
| Qin Huang, Rui Liu, Shen Gui, Jinling Lu, Pengcheng L. Bilateral sensory disturbance after cortical spreading depression revealed by fluorescence imaging of voltage-sensitive dye. Journal of biophotonics. vol 11. issue 7. 2019-10-21. PMID:29512922. |
cortical spreading depression (csd), a propagation wave of transient neuronal and glial depolarization followed by suppression of spontaneous brain activity, has been hypothesized to be the underlying mechanism of migraine aura and triggers the headache attack. |
2019-10-21 |
2023-08-13 |
mouse |
| Aaron J Schain, Agustin Melo-Carrillo, David Borsook, Jaime Grutzendler, Andrew M Strassman, Rami Burstei. Activation of pial and dural macrophages and dendritic cells by cortical spreading depression. Annals of neurology. vol 83. issue 3. 2019-07-31. PMID:29394508. |
cortical spreading depression (csd) has long been implicated in migraine attacks with aura. |
2019-07-31 |
2023-08-13 |
Not clear |
| David Gaist, Anders Hougaard, Ellen Garde, Nina Linde Reislev, Rikke Wiwie, Pernille Iversen, Camilla Gøbel Madsen, Morten Blaabjerg, Helle Hvilsted Nielsen, Thomas Krøigård, Kamilla Østergaard, Kirsten Ohm Kyvik, Jacob Hjelmborg, Kristoffer Madsen, Hartwig Roman Siebner, Messoud Ashin. Migraine with visual aura associated with thicker visual cortex. Brain : a journal of neurology. vol 141. issue 3. 2019-06-27. PMID:29360944. |
however, recent mri studies have reported increased cortical thickness of visual and somatosensory areas in patients with migraine with aura, suggesting that such structural alterations were either due to increased neuronal density in the areas involved, or a result of multiple episodes of cortical spreading depression as part of aura attacks. |
2019-06-27 |
2023-08-13 |
human |
| Marta Vila-Pueyo, Lauren C Strother, Malak Kefel, Peter J Goadsby, Philip R Hollan. Divergent influences of the locus coeruleus on migraine pathophysiology. Pain. vol 160. issue 2. 2019-06-26. PMID:30371556. |
in addition, we explored the susceptibility to cortical spreading depression initiation, the presumed underlying phenomenon of migraine aura. |
2019-06-26 |
2023-08-13 |
Not clear |
| Gretchen E Tietjen, Stuart A Collin. Hypercoagulability and Migraine. Headache. vol 58. issue 1. 2019-03-27. PMID:28181217. |
the theory that micro-emboli induced ischemia provokes cortical spreading depression (ie, symptomatic aura) in migraineurs but transient ischemic attacks in others highlights a potential role for hypercoagulability as a link between migraine (with aura) and stroke. |
2019-03-27 |
2023-08-13 |
Not clear |
| Nazia Karsan, Eric B Gonzales, Gregory Dusso. Targeted Acid-Sensing Ion Channel Therapies for Migraine. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 15. issue 2. 2019-03-13. PMID:29549622. |
their expression within areas of interest in the brain in migraine, such as the hypothalamus and pag, their demonstrated involvement in preclinical models of meningeal afferent signaling, and their role in cortical spreading depression (the electrophysiological correlate of migraine aura), has enhanced research interest into these channels as potential therapeutic targets in migraine. |
2019-03-13 |
2023-08-13 |
Not clear |
| Liwen Jiang, Yan Wang, Yuewei Xu, Dongqing Ma, Minyan Wan. The Transient Receptor Potential Ankyrin Type 1 Plays a Critical Role in Cortical Spreading Depression. Neuroscience. vol 382. 2019-03-07. PMID:29719223. |
cortical spreading depression (csd) is known as an underlying cause of migraine aura. |
2019-03-07 |
2023-08-13 |
mouse |
| Hale Yapıcı-Eser, Buket Dönmez-Demir, Kıvılcım Kılıç, Emine Eren-Koçak, Turgay Dalkar. Stress modulates cortical excitability via α-2 adrenergic and glucocorticoid receptors: As assessed by spreading depression. Experimental neurology. vol 307. 2019-02-20. PMID:29856967. |
since stress increases extracellular glutamate and predisposes to migraine with aura attacks, we aimed to study the effect of stress on cortical spreading depression (csd), the biological substrate of migraine aura and a measure of cortical excitability. |
2019-02-20 |
2023-08-13 |
mouse |
| Lyudmila V Vinogradov. Initiation of spreading depression by synaptic and network hyperactivity: Insights into trigger mechanisms of migraine aura. Cephalalgia : an international journal of headache. vol 38. issue 6. 2019-02-08. PMID:28750590. |
initiation of spreading depression by synaptic and network hyperactivity: insights into trigger mechanisms of migraine aura. |
2019-02-08 |
2023-08-13 |
Not clear |
| Lyudmila V Vinogradov. Initiation of spreading depression by synaptic and network hyperactivity: Insights into trigger mechanisms of migraine aura. Cephalalgia : an international journal of headache. vol 38. issue 6. 2019-02-08. PMID:28750590. |
background cortical spreading depression (sd) is thought to underlie migraine aura but mechanisms of triggering sd in the structurally normal, well-nourished cortex of migraine patients remain unknown. |
2019-02-08 |
2023-08-13 |
Not clear |
| Virginie Chauvel, Sylvie Multon, Jean Schoene. Estrogen-dependent effects of 5-hydroxytryptophan on cortical spreading depression in rat: Modelling the serotonin-ovarian hormone interaction in migraine aura. Cephalalgia : an international journal of headache. vol 38. issue 3. 2019-01-25. PMID:28145727. |
estrogen-dependent effects of 5-hydroxytryptophan on cortical spreading depression in rat: modelling the serotonin-ovarian hormone interaction in migraine aura. |
2019-01-25 |
2023-08-13 |
rat |
| Virginie Chauvel, Sylvie Multon, Jean Schoene. Estrogen-dependent effects of 5-hydroxytryptophan on cortical spreading depression in rat: Modelling the serotonin-ovarian hormone interaction in migraine aura. Cephalalgia : an international journal of headache. vol 38. issue 3. 2019-01-25. PMID:28145727. |
background cortical spreading depression (csd) is the likely culprit of the migraine aura. |
2019-01-25 |
2023-08-13 |
rat |
| Geneviève Demarquay, Anne Ducros, Alexandra Montavont, François Mauguier. Migraine with brainstem aura: Why not a cortical origin? Cephalalgia : an international journal of headache. vol 38. issue 10. 2019-01-25. PMID:29073774. |
this hypothesis would explain the co-occurrence of typical and brainstem aura during attacks and would fit with the theory of cortical spreading depression. |
2019-01-25 |
2023-08-13 |
Not clear |
| Buket Dönmez-Demir, Muge Yemisci, Kıvılcım Kılıç, Yasemin Gürsoy-Özdemir, Figen Söylemezoğlu, Michael Moskowitz, Turgay Dalkar. Microembolism of single cortical arterioles can induce spreading depression and ischemic injury; a potential trigger for migraine and related MRI lesions. Brain research. vol 1679. 2018-08-09. PMID:29183666. |
single mouse penetrating arteriole - pa), can induce cortical spreading depression (csd), the putative cause of migraine aura and, hence, trigger an ma attack. |
2018-08-09 |
2023-08-13 |
mouse |
| Shih-Pin Chen, Cenk Ayat. Novel Therapeutic Targets Against Spreading Depression. Headache. vol 57. issue 9. 2018-06-04. PMID:28842982. |
cortical spreading depression (sd) is an intense wave of neuronal and glial depolarization underlying migraine aura, and a headache trigger, which has been used as an experimental platform for drug screening in migraine. |
2018-06-04 |
2023-08-13 |
Not clear |
| Stuart M Cain, Barry Bohnet, Jeffrey LeDue, Andrew C Yung, Esperanza Garcia, John R Tyson, Sascha R A Alles, Huili Han, Arn M J M van den Maagdenberg, Piotr Kozlowski, Brian A MacVicar, Terrance P Snutc. In vivo imaging reveals that pregabalin inhibits cortical spreading depression and propagation to subcortical brain structures. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 9. 2018-04-10. PMID:28223480. |
migraine is characterized by severe headaches that can be preceded by an aura likely caused by cortical spreading depression (sd). |
2018-04-10 |
2023-08-13 |
mouse |
| Domenico Chirchiglia, Michele Andreucci, Attilio Della Torre, Serena Marianna Lavano, Pasquale Chirchiglia, Angelo Lavan. New-onset hemodialysis-related headache presenting as migraine aura. Neurologia i neurochirurgia polska. vol 51. issue 5. 2018-03-20. PMID:28688801. |
role of trigeminal-vascular system and cortical spreading depression as regards the aura could be considered, through the activation of neuroinflammatory events, lastly causing migraine aura. |
2018-03-20 |
2023-08-13 |
Not clear |