| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Burak Uzay, Buket Donmez-Demir, Sinem Yilmaz Ozcan, Emine Eren Kocak, Muge Yemisci, Yasemin Gursoy Ozdemir, Turgay Dalkara, Hulya Karata. The effect of P2X7 antagonism on subcortical spread of optogenetically-triggered cortical spreading depression and neuroinflammation. The journal of headache and pain. vol 25. issue 1. 2024-07-24. PMID:39044141. |
cortical spreading depression (csd), the electrophysiological equivalent of migraine aura, results in opening of pannexin 1 megachannels that release atp and triggers parenchymal neuroinflammatory signaling cascade in the cortex. |
2024-07-24 |
2024-07-26 |
Not clear |
| Martin Kaag Rasmussen, Kjeld Møllgård, Peter A R Bork, Pia Weikop, Tina Esmail, Lylia Drici, Nicolai J Wewer Albrechtsen, Jonathan Frederik Carlsen, Nguyen P T Huynh, Nima Ghitani, Matthias Mann, Steven A Goldman, Yuki Mori, Alexander T Chesler, Maiken Nedergaar. Trigeminal ganglion neurons are directly activated by influx of CSF solutes in a migraine model. Science (New York, N.Y.). vol 385. issue 6704. 2024-07-04. PMID:38963846. |
classical migraine patients experience aura, which is transient neurological deficits associated with cortical spreading depression (csd), preceding headache attacks. |
2024-07-04 |
2024-07-11 |
mouse |
| Meng-Fan Yang, Dong-Xue Ren, Xue Pan, Chang-Xin Li, Sui-Yi X. The Role of Astrocytes in Migraine with Cortical Spreading Depression: Protagonists or Bystanders? A Narrative Review. Pain and therapy. 2024-05-14. PMID:38743247. |
cortical spreading depression (csd) is a slow wave of cortical depolarization closely associated with migraines with an aura. |
2024-05-14 |
2024-05-27 |
Not clear |
| Tzu-Ting Liu, Shih-Pin Chen, Shuu-Jiun Wang, Jiin-Cherng Ye. Vagus nerve stimulation inhibits cortical spreading depression via glutamate-dependent TrkB activation mechanism in the nucleus tractus solitarius. Cephalalgia : an international journal of headache. vol 44. issue 2. 2024-02-08. PMID:38329067. |
vagus nerve stimulation (vns) was recently found to inhibit cortical spreading depression (csd), the underlying mechanism of migraine aura, through activation of the nucleus tractus solitarius (nts), locus coeruleus (lc) and dorsal raphe nucleus (drn). |
2024-02-08 |
2024-02-10 |
Not clear |
| Tatiana M Medvedeva, Maria P Smirnova, Irina V Pavlova, Lyudmila V Vinogradov. Different vulnerability of fast and slow cortical oscillations to suppressive effect of spreading depolarization: state-dependent features potentially relevant to pathogenesis of migraine aura. The journal of headache and pain. vol 25. issue 1. 2024-01-15. PMID:38225575. |
sweeping across the cortex, the electrocorticographic depression is supposed to underlie spreading negative symptoms of migraine aura. |
2024-01-15 |
2024-01-18 |
Not clear |
| Tatiana M Medvedeva, Maria P Smirnova, Irina V Pavlova, Lyudmila V Vinogradov. Different vulnerability of fast and slow cortical oscillations to suppressive effect of spreading depolarization: state-dependent features potentially relevant to pathogenesis of migraine aura. The journal of headache and pain. vol 25. issue 1. 2024-01-15. PMID:38225575. |
main information about the suppressive effect of sd on cortical oscillations was obtained in anesthetized animals while ictal recordings in conscious patients failed to detect eeg depression during migraine aura. |
2024-01-15 |
2024-01-18 |
Not clear |
| Margarita Sanchez Del Rio, Fred Michael Cutre. Pathophysiology of migraine aura. Handbook of clinical neurology. vol 198. 2023-12-03. PMID:38043972. |
investigations during physiologically induced visual auras suggest that the phenomenon of cortical spreading depression or its human equivalent underpins the migraine aura. |
2023-12-03 |
2023-12-10 |
human |
| Peter J Koehler, Christopher J Boe. History of migraine. Handbook of clinical neurology. vol 198. 2023-12-03. PMID:38043968. |
aura and cortical spreading depression were studied in the early 1940s and related to spreading oligemia in the 1980s. |
2023-12-03 |
2023-12-10 |
human |
| Marina Vitale, Angelita Tottene, Maral Zarin Zadeh, K C Brennan, Daniela Pietrobo. Mechanisms of initiation of cortical spreading depression. The journal of headache and pain. vol 24. issue 1. 2023-08-08. PMID:37553625. |
there is increasing evidence from human and animal studies that cortical spreading depression (csd) is the neurophysiological correlate of migraine aura and a trigger of migraine pain mechanisms. |
2023-08-08 |
2023-08-16 |
mouse |
| Adrian Scutelnic, Hristina Drangova, Antonia Klein, Nedelina Slavova, Morin Beyeler, Julian Lippert, Norbert Silimon, Thomas R Meinel, Marcel Arnold, Urs Fischer, Franz Riederer, Heinrich P Mattle, Simon Jung, Christoph J Schanki. Changes of migraine aura with advancing age of patients. The journal of headache and pain. vol 24. issue 1. 2023-08-01. PMID:37528414. |
experimental studies indicate a decrease in the magnitude of cortical spreading depression (csd), the pathophysiological correlate of migraine aura, with advancing age. |
2023-08-01 |
2023-08-14 |
Not clear |
| Daisuke Danno, Kumiko Ishizaki, Shoji Kikui, Takao Takeshim. Treatment of hemiplegic migraine with anti-calcitonin gene-related peptide monoclonal antibodies: A case series in a tertiary-care headache center. Headache. 2023-06-27. PMID:37366160. |
the mechanism underlying the improvement in aura symptoms in our patients is not clear; however, we speculate that a small amount of cgrp mabs have a direct mode of action in the central nervous system; alternatively, blocking the cgrp pathway in the periphery may secondarily inhibit cortical spreading depression. |
2023-06-27 |
2023-08-14 |
Not clear |
| Andreia Morais, Tao Qin, Cenk Ayata, Andrea M Harriot. Inhibition of persistent sodium current reduces spreading depression-evoked allodynia in a mouse model of migraine with aura. Pain. 2023-06-15. PMID:37318029. |
cortical spreading depression (sd) is a slow wave of neuronal and glial depolarization that underlies the migraine aura. |
2023-06-15 |
2023-08-14 |
mouse |
| Chiho Kudo, Andrea M Harriott, Michael A Moskowitz, Christian Waeber, Cenk Ayat. Estrogen modulation of cortical spreading depression. The journal of headache and pain. vol 24. issue 1. 2023-05-26. PMID:37237336. |
cortical spreading depression (csd), a transient neuronal and glial depolarization that propagates slowly across the cerebral cortex, is the putative electrophysiological event underlying migraine aura and a headache trigger. |
2023-05-26 |
2023-08-14 |
Not clear |
| Ákos Menyhárt, Armand Rafael Bálint, Péter Kozák, Ferenc Bari, Eszter Farka. Nimodipine accelerates the restoration of functional hyperemia during spreading oligemia. Journal of neurochemistry. 2023-02-22. PMID:36810711. |
spreading depolarization (sd) is assumed to be the pathophysiological correlate of migraine aura, leading to spreading depression of activity and a long-lasting vasoconstriction known as spreading oligemia. |
2023-02-22 |
2023-08-14 |
mouse |
| Chenghui Pi, Wenjing Tang, Zhishuai Li, Yang Liu, Qi Jing, Wei Dai, Tao Wang, Chunxiao Yang, Shengyuan Y. Cortical pain induced by optogenetic cortical spreading depression: from whole brain activity mapping. Molecular brain. vol 15. issue 1. 2022-12-05. PMID:36471383. |
cortical spreading depression (csd) is an electrophysiological event underlying migraine aura. |
2022-12-05 |
2023-08-14 |
Not clear |
| Msallam Abbas Abdulhussein, Zaid Abdi Alkareem Alyasseri, Husam Jasim Mohammed, Xingwei A. Lack of Habituation in Migraine Patients Based on High-Density EEG Analysis Using the Steady State of Visual Evoked Potential. Entropy (Basel, Switzerland). vol 24. issue 11. 2022-11-24. PMID:36421543. |
several studies indicated that the reason for migraine aura is cortical spreading depression (csd) but did not clarify its impact on migraine without aura and lack of habituation. |
2022-11-24 |
2023-08-14 |
human |
| Sahin Hanalioglu, Aslihan Taskiran-Sag, Hulya Karatas, Buket Donmez-Demir, Sinem Yilmaz-Ozcan, Emine Eren-Kocak, Yasemin Gursoy-Ozdemir, Turgay Dalkar. Cortical spreading depression can be triggered by sensory stimulation in primed wild type mouse brain: a mechanistic insight to migraine aura generation. The journal of headache and pain. vol 23. issue 1. 2022-08-19. PMID:35986251. |
cortical spreading depression can be triggered by sensory stimulation in primed wild type mouse brain: a mechanistic insight to migraine aura generation. |
2022-08-19 |
2023-08-14 |
mouse |
| Sahin Hanalioglu, Aslihan Taskiran-Sag, Hulya Karatas, Buket Donmez-Demir, Sinem Yilmaz-Ozcan, Emine Eren-Kocak, Yasemin Gursoy-Ozdemir, Turgay Dalkar. Cortical spreading depression can be triggered by sensory stimulation in primed wild type mouse brain: a mechanistic insight to migraine aura generation. The journal of headache and pain. vol 23. issue 1. 2022-08-19. PMID:35986251. |
unlike the spontaneously appearing aura in migraineurs, experimentally, cortical spreading depression (csd), the neurophysiological correlate of aura is induced by non-physiological stimuli. |
2022-08-19 |
2023-08-14 |
mouse |
| Zachariah Bertels, Isaac J Dripps, Pal Shah, Laura S Moye, Alycia F Tipton, Kendra Siegersma, Amynah A Pradha. Delta opioid receptors in Nav1.8 expressing peripheral neurons partially regulate the effect of delta agonist in models of migraine and opioid-induced hyperalgesia. Neurobiology of pain (Cambridge, Mass.). vol 12. 2022-07-21. PMID:35859654. |
regardless of genotype, snc80 continued to inhibit conditioned place aversion associated with nitroglycerin and decreased cortical spreading depression events associated with migraine aura. |
2022-07-21 |
2023-08-14 |
mouse |
| Laurence Bourgeais-Rambur, Laurianne Beynac, Jean-Charles Mariani, Mickael Tanter, Thomas Deffieux, Zsolt Lenkei, Luis Villanuev. Altered cortical trigeminal fields excitability by spreading depolarization revealed with The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-07-11. PMID:35817577. |
altered cortical trigeminal fields excitability by spreading depolarization revealed with spreading depolarization (sd), usually termed cortical spreading depression has been proposed as the pathophysiological substrate of migraine aura and as an endogenous trigger of headache pain. |
2022-07-11 |
2023-08-14 |
Not clear |